Design TherapeuticsDSGN
13F holders, Q2 2026 (June 30)136holders +11
27new positions
16sold out
6famous investors
$14.47avg. 13F price*
At the end of Q2 2026, 136 institutions reported holding Design Therapeutics Inc. (DSGN) in their 13F filings, up 11 from Q1 2026. 27 opened new positions and 16 sold out. The largest holders were SR One Capital Management, LP ($94.4M), Logos Global Management LP ($43.4M) and Baker Bros. Advisors LP ($38.8M). 6 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Design Therapeutics Inc.
- CUSIP
- 25056L103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $61.8M |
| Exits | 16 | $46.0M |
All 13F filers, Q1 2026 → Q2 2026: 12,033,814 shares bought and 6,719,669 shares sold, net +5,314,145 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 136 holders
| SR One Capital Management, LP | 9.09% | No change | 6,526,476 | $94.4M |
| Logos Global Management LP | 1.87% | Add +53.9% | 3,000,000 | $43.4M |
| Baker Bros. Advisors LP | 0.19% | Add +3.6% | 2,678,430 | $38.8M |
| Driehaus Capital Management LLC | 0.22% | Add +52.5% | 2,661,115 | $38.5M |
| BlackRock, Inc. | 0.00% | Add +24.7% | 2,660,024 | $38.5M |
| Point72 Asset Management | 0.05% | Reduce -13.1% | 2,366,453 | $34.2M |
| Trails Edge Capital Partners, LP | 4.60% | Add +134.9% | 2,001,282 | $29.0M |
| Frazier Life Sciences Management, L.P. | 0.57% | New | 1,809,854 | $26.2M |
| Vivo Capital, LLC | 2.13% | No change | 1,612,903 | $23.3M |
| Vanguard Capital Management LLC | 0.00% | Add +16.4% | 1,571,022 | $22.7M |
| Caption Management, LLC | 0.59% | Add +1189.5% | 1,118,098 | $16.2M |
| Almitas Capital LLC | 3.56% | Reduce -32.9% | 1,026,893 | $14.9M |
| Geode Capital Management, LLC | 0.00% | Add +38.4% | 958,417 | $13.9M |
| Sofinnova Investments, Inc. | 0.67% | New | 865,135 | $12.5M |
| FMR LLC | 0.00% | Reduce -2.8% | 776,462 | $11.2M |
| Morgan Stanley | 0.00% | Add +16.6% | 765,425 | $11.1M |
| State Street Corp. | 0.00% | Add +11.6% | 736,221 | $10.7M |
| Woodline Partners LP | 0.03% | Reduce -27.2% | 700,354 | $10.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +60.9% | 694,743 | $10.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +30.1% | 656,584 | $9.5M |
| Jacobs Levy Equity Management, Inc. | 0.03% | Add +95.5% | 565,597 | $8.2M |
| Acadian Asset Management LLC | 0.01% | Reduce -12.8% | 537,479 | $7.8M |
| Siren, L.L.C. | 0.15% | New | 523,212 | $7.6M |
| Qube Research & Technologies Ltd | 0.01% | Add +1178.6% | 437,079 | $6.3M |
| Renaissance Technologies | 0.01% | Reduce -5.0% | 387,913 | $5.6M |
| Kennedy Capital Management LLC | 0.10% | Add +41.4% | 384,036 | $5.6M |
| Northern Trust Corp. | 0.00% | Add +17.6% | 353,197 | $5.1M |
| Algert Global LLC | 0.05% | Add +44.6% | 296,085 | $4.3M |
| Acuta Capital Partners, LLC | 2.85% | Add +93.7% | 282,564 | $4.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +12.3% | 271,264 | $3.9M |
| Vanguard Portfolio Management LLC | 0.00% | Add +81.5% | 251,442 | $3.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +17.7% | 230,202 | $3.3M |
| Prudential Financial Inc. | 0.00% | Add +389.4% | 224,170 | $3.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -58.4% | 195,645 | $2.8M |
| Eversept Partners, LP | 0.15% | New | 190,000 | $2.7M |
| KVP Capital Advisors, LP | 1.96% | New | 185,000 | $2.7M |
| J. Goldman & Co LP | 0.09% | New | 176,770 | $2.6M |
| Millennium Management | 0.00% | Add +35.6% | 147,714 | $2.1M |
| Raymond James Financial Inc. | 0.00% | Add +27.7% | 138,521 | $2.0M |
| Balyasny Asset Management L.P. | 0.00% | New | 111,103 | $1.6M |
| Elmind Capital, LP | 0.39% | Reduce -48.1% | 107,900 | $1.6M |
| Nuveen, LLC | 0.00% | Reduce -17.4% | 104,734 | $1.5M |
| DAFNA Capital Management LLC | 0.28% | New | 102,600 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Add +15.6% | 92,069 | $1.3M |
| China Universal Asset Management Co., Ltd. | 0.08% | Add +156.2% | 89,940 | $1.3M |
| Citadel Advisors | 0.00% | Reduce -64.6% | 81,971 | $1.2M |
| SummitTX Capital, L.P. | 0.03% | New | 80,663 | $1.2M |
| American Century Companies Inc. | 0.00% | Add +17.0% | 76,825 | $1.1M |
| Palumbo Wealth Management LLC | 0.22% | Add +0.5% | 71,744 | $1.0M |
| AQR Capital Management | 0.00% | Add +174.0% | 71,114 | $1.0M |
| Ameriprise Financial Inc. | 0.00% | Add +93.2% | 67,598 | $978K |
| Russell Investments Group, Ltd. | 0.00% | Add +162.8% | 66,859 | $967K |
| Alps Advisors Inc. | 0.00% | Add +26.3% | 63,391 | $917K |
| State of Wisconsin Investment Board | 0.00% | Add +20.4% | 59,249 | $857K |
| STRS Ohio | 0.00% | Add +13.0% | 50,500 | $731K |
| Verdad Advisers, LP | 0.66% | Reduce -48.5% | 47,557 | $688K |
| Bank of America Corp. | 0.00% | Add +88.0% | 43,728 | $633K |
| ExodusPoint Capital Management, LP | 0.01% | New | 41,286 | $597K |
| Rhumbline Advisers | 0.00% | Add +9.4% | 38,132 | $552K |
| Vanguard Global Advisers, LLC | 0.00% | Add +200.1% | 35,534 | $514K |
| UBS Group AG | 0.00% | Add +103.4% | 34,761 | $503K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | New | 33,375 | $483K |
| Two Sigma Investments, LP | 0.00% | Add +102.0% | 32,925 | $476K |
| Canada Pension Plan Investment Board | 0.00% | Reduce -46.0% | 32,600 | $472K |
| Oppenheimer & Co. Inc. | 0.01% | New | 32,087 | $464K |
| Alliancebernstein L.P. | 0.00% | Reduce -6.3% | 43,230 | $460K |
| Deutsche Bank AG | 0.00% | Add +48.3% | 30,613 | $443K |
| Virtus Investment Advisers, LLC | 0.10% | New | 29,827 | $432K |
| Squarepoint Ops LLC | 0.00% | Reduce -65.6% | 29,630 | $429K |
| Trexquant Investment LP | 0.00% | Reduce -76.0% | 28,150 | $407K |
| Wells Fargo & Company | 0.00% | Add +211.0% | 28,072 | $406K |
| Corient Private Wealth LP | 0.00% | No change | 27,169 | $393K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -48.1% | 27,000 | $391K |
| Quantinno Capital Management LP | 0.00% | Add +90.4% | 26,901 | $389K |
| T. Rowe Price Associates Inc. | 0.00% | Add +56.4% | 25,606 | $371K |
| Sei Investments Co. | 0.00% | Reduce -82.9% | 22,740 | $329K |
| XTX Topco Ltd | 0.00% | Reduce -63.3% | 22,383 | $324K |
| AlphaCentric Advisors LLC | 0.26% | Add +1.4% | 21,537 | $312K |
| Invesco Ltd. | 0.00% | Reduce -84.9% | 21,429 | $310K |
| Public Employees Retirement System of Ohio | 0.00% | Add +36.3% | 20,700 | $300K |
| MetLife Investment Management, LLC | 0.00% | Add +35.1% | 20,609 | $298K |
| Wellington Management Group LLP | 0.00% | New | 19,400 | $281K |
| JPMorgan Chase & Co. | 0.00% | Add +19.6% | 16,904 | $241K |
| Citigroup Inc. | 0.00% | Add +272.5% | 15,880 | $230K |
| Creative Planning | 0.00% | New | 15,844 | $229K |
| Susquehanna International Group, LLP | 0.00% | New | 15,650 | $226K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 14,824 | $215K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +24.7% | 14,171 | $205K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 12,910 | $187K |
| Susquehanna Fundamental Investments, LLC | 0.00% | New | 12,553 | $182K |
| Royal Bank of Canada | 0.00% | Add +7.8% | 12,254 | $178K |
| Barclays PLC | 0.00% | Reduce -79.0% | 11,707 | $169K |
| New York State Common Retirement Fund | 0.00% | Add +434.4% | 10,826 | $157K |
| Gsa Capital Partners LLP | 0.01% | New | 10,328 | $149K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +49.3% | 9,849 | $143K |
| BNP Paribas Financial Markets | 0.00% | Reduce -88.6% | 5,751 | $83K |
| Clearstead Advisors, LLC | 0.00% | Add +819.7% | 5,610 | $81K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +217.7% | 4,908 | $71K |
| Rockefeller Capital Management L.P. | 0.00% | No change | 3,684 | $53K |
| Caz Investments LP | 0.02% | No change | 3,500 | $51K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +89.8% | 3,025 | $44K |
| Legal & General Group Plc | 0.00% | Add +43.8% | 2,987 | $43K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +8.7% | 2,793 | $40K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -6.0% | 2,793 | $40K |
| State of Wyoming | 0.00% | New | 2,566 | $37K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,816 | $26K |
| GAMMA Investing LLC | 0.00% | Reduce -1.5% | 1,450 | $21K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +125800.0% | 1,259 | $18K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -4.9% | 1,209 | $17K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | No change | 1,143 | $17K |
| Allied Private Wealth LLC | 0.01% | — | 880 | $13K |
| Private Wealth Management Group, LLC | 0.00% | No change | 533 | $8K |
| California State Teachers Retirement System | 0.00% | Reduce -74.1% | 335 | $5K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 268 | $4K |
| Stone House Investment Management, LLC | 0.00% | No change | 239 | $3K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 239 | $3K |
| Osaic Holdings, Inc. | 0.00% | Reduce -26.5% | 225 | $3K |
| Larson Financial Group LLC | 0.00% | No change | 181 | $3K |
| Arax Advisory Partners | 0.00% | New | 180 | $3K |
| Simplex Trading, LLC | 0.00% | New | 172 | $2K |
| Optiver Holding B.V. | 0.00% | Reduce -28.6% | 160 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -86.3% | 108 | $2K |
| Allworth Financial LP | 0.00% | Reduce -26.1% | 96 | $1K |
| Versant Capital Management, Inc | 0.00% | New | 86 | $1K |
| National Bank of Canada | 0.00% | Add +822.2% | 83 | $1K |
| Silver Grove Financial Group, Inc. | 0.00% | New | 58 | $839 |
| Quarry LP | 0.00% | New | 31 | $449 |
| US Bancorp \de | 0.00% | Reduce -57.4% | 26 | $376 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +150.0% | 25 | $362 |
| Rothschild Investment LLC | 0.00% | Reduce -4.3% | 22 | $318 |
| Farther Finance Advisors, LLC | 0.00% | Reduce -94.8% | 20 | $289 |
| True Wealth Design, LLC | 0.00% | Add +1700.0% | 18 | $261 |
| SBI Securities Co., Ltd. | 0.00% | New | 10 | $145 |
| SJS Investment Consulting Inc. | 0.00% | New | 4 | $58 |
| Essential Partners LLC | 0.00% | No change | 1 | $14 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 12 | $0 |
"% of holder's portfolio" is DSGN's weight in each manager's 13F, not the share of Design Therapeutics Inc. the manager owns.