Enliven TherapeuticsELVN

13F holders, Q4 2025 (December 31)
126holders −8
17new positions
26sold out
4famous investors
$15.40avg. 13F price*

At the end of Q4 2025, 126 institutions reported holding Enliven Therapeutics Inc. (ELVN) in their 13F filings, down 8 from Q3 2025. 17 opened new positions and 26 sold out. The largest holders were Orbimed Advisors LLC ($122.6M), FMR LLC ($109.5M) and Commodore Capital LP ($72.3M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Enliven Therapeutics Inc.
CUSIP
29337E102
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 74Q1 2024Q2 2024: 93Q2 2024Q3 2024: 102Q3 2024Q4 2024: 113Q4 2024Q1 2025: 121Q1 2025Q2 2025: 124Q2 2025Q3 2025: 134Q3 2025Q4 2025: 126Q4 2025Q1 2026: 170Q1 2026Q2 2026: 212Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions17$25.7M
Exits26$58.9M

All 13F filers, Q3 2025 → Q4 2025: 7,166,732 shares bought and 4,913,259 shares sold, net +2,253,473 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 126 holders

Orbimed Advisors LLC 2.51% No change 7,959,538 $122.6M
FMR LLC 0.01% Reduce -0.3% 7,107,635 $109.5M
Commodore Capital LP 4.81% No change 4,692,809 $72.3M
Vestal Point Capital, LP 2.16% Add +230.2% 3,830,000 $59.0M
Fairmount Funds Management LLC 4.35% No change 3,711,444 $57.2M
BlackRock, Inc. 0.00% Add +2.7% 3,613,326 $55.6M
Polar Capital Holdings Plc 0.25% Add +13.5% 3,513,680 $54.1M
Venrock Adviser, LLC 2.45% No change 3,226,331 $49.7M
Vanguard Group Inc. 0.00% Add +9.7% 2,801,665 $43.1M
Janus Henderson Group PLC 0.01% Reduce -6.8% 1,671,724 $25.7M
Point72 Asset Management 0.04% Add +44.6% 1,504,601 $23.2M
Novo Holdings A/S 1.77% Add +3.8% 1,480,000 $22.8M
Citadel Advisors 0.02% Add +22.7% 1,424,344 $21.9M
Capital Research Global Investors 0.00% Reduce -0.8% 1,304,346 $20.1M
Pictet Asset Management Holding SA 0.02% Reduce -6.8% 1,303,235 $20.1M
State Street Corp. 0.00% Add +9.1% 1,052,862 $16.2M
Geode Capital Management, LLC 0.00% Reduce -3.3% 1,048,722 $16.2M
Soleus Capital Management, L.P. 0.67% New 1,025,000 $15.8M
Blackstone Inc. 0.06% Reduce -27.7% 954,946 $14.7M
Rock Springs Capital Management LP 0.63% Add +16.4% 798,405 $12.3M
5AM Venture Management, LLC 3.74% No change 772,477 $11.9M
Candriam S.C.A. 0.03% Reduce -25.7% 453,019 $7.0M
Spruce Street Capital LP 2.27% — 446,084 $6.9M
Morgan Stanley 0.00% Add +59.4% 411,823 $6.3M
Dimensional Fund Advisors LP 0.00% Add +148.6% 398,893 $6.1M
Marshall Wace, LLP 0.01% Add +9.2% 371,906 $5.7M
Charles Schwab Investment Management Inc. 0.00% Reduce -2.2% 355,192 $5.5M
Northern Trust Corp. 0.00% Reduce -10.7% 352,239 $5.4M
Logos Global Management LP 0.35% No change 340,000 $5.2M
Patient Square Capital LP 1.02% Add +22.8% 308,141 $4.7M
Woodline Partners LP 0.02% Add +0.2% 301,023 $4.6M
Millennium Management 0.00% Reduce -22.1% 296,947 $4.6M
Baker Bros. Advisors LP 0.02% Add +136.3% 271,406 $4.2M
Goldman Sachs Group Inc. 0.00% Reduce -9.6% 237,204 $3.7M
Sphera Funds Management LTD. 0.73% Add +36.0% 226,765 $3.5M
Exome Asset Management LLC 1.69% New 222,308 $3.4M
Trails Edge Capital Partners, LP 0.76% — 199,306 $3.1M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +459.9% 194,735 $3.0M
Avidity Partners Management LP 0.62% No change 140,300 $2.2M
Wellington Management Group LLP 0.00% Add +19.6% 129,876 $2.0M
Bank of New York Mellon Corp 0.00% Reduce -4.4% 110,569 $1.7M
Nuveen, LLC 0.00% Reduce -2.6% 105,448 $1.6M
Jane Street Group, LLC 0.00% New 101,971 $1.6M
Seven Fleet Capital Management LP 1.04% — 99,953 $1.5M
HighVista Strategies LLC 0.33% Reduce -68.2% 82,536 $1.3M
Barclays PLC 0.00% Reduce -1.1% 69,875 $1.1M
Lighthouse Investment Partners, LLC 0.03% New 65,000 $1.0M
Swiss National Bank 0.00% Add +1.7% 64,273 $990K
XTX Topco Ltd 0.02% Add +472.6% 60,702 $935K
ExodusPoint Capital Management, LP 0.01% Add +25.5% 60,415 $930K
UBS Group AG 0.00% Reduce -27.2% 57,868 $891K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +6.8% 55,210 $850K
Prelude Capital Management, LLC 0.06% New 52,578 $810K
Rhumbline Advisers 0.00% Reduce -16.0% 50,509 $778K
Susquehanna Portfolio Strategies, LLC 0.01% Add +53.6% 48,741 $751K
American Century Companies Inc. 0.00% Add +297.9% 45,792 $705K
Jump Financial, LLC 0.01% New 45,354 $698K
Wells Fargo & Company 0.00% Add +66.7% 43,056 $663K
Alliancebernstein L.P. 0.00% No change 36,840 $567K
Prudential Financial Inc. 0.00% New 35,580 $548K
Bank of America Corp. 0.00% Add +38.9% 32,711 $504K
California State Teachers Retirement System 0.00% Add +58.4% 32,206 $496K
Deutsche Bank AG 0.00% Add +24.7% 31,420 $484K
ADAR1 Capital Management, LLC 0.03% New 30,000 $462K
Tudor Investment Corporation 0.00% Add +82.0% 29,673 $457K
Aquatic Capital Management LLC 0.01% New 27,955 $431K
Legal & General Group Plc 0.00% Reduce -19.9% 27,059 $417K
Invesco Ltd. 0.00% Add +7.0% 24,720 $381K
MetLife Investment Management, LLC 0.00% No change 24,556 $378K
T. Rowe Price Associates Inc. 0.00% Reduce -89.7% 23,800 $367K
Squarepoint Ops LLC 0.00% Reduce -42.1% 20,763 $320K
JPMorgan Chase & Co. 0.00% Reduce -16.6% 20,701 $319K
State of Wisconsin Investment Board 0.00% Reduce -57.2% 20,398 $314K
Franklin Resources Inc. 0.00% Reduce -95.3% 20,167 $311K
Manufacturers Life Insurance Company, The 0.00% Reduce -56.1% 19,336 $298K
Ameriprise Financial Inc. 0.00% Reduce -84.6% 18,949 $292K
Citigroup Inc. 0.00% Add +57.4% 18,489 $285K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -6.4% 18,287 $282K
Intech Investment Management LLC 0.00% Add +15.6% 16,729 $258K
Virtus Investment Advisers, LLC 0.07% Add +172.7% 15,778 $243K
Axq Capital, LP 0.05% New 14,244 $219K
SG Americas Securities, LLC 0.00% Reduce -36.9% 14,035 $216K
Fox Run Management, L.L.C. 0.03% New 12,432 $191K
Police & Firemen's Retirement System of New Jersey 0.00% Add +1.1% 11,162 $172K
Canada Pension Plan Investment Board 0.00% New 10,800 $166K
State Board of Administration of Florida Retirement System 0.00% No change 10,480 $161K
AlphaQuest LLC 0.01% Add +119.9% 10,337 $159K
Landscape Capital Management, L.L.C. 0.01% No change 10,301 $159K
Profund Advisors LLC 0.00% New 10,179 $157K
BNP Paribas Financial Markets 0.00% Add +5.8% 9,672 $149K
China Universal Asset Management Co., Ltd. 0.01% Reduce -6.9% 9,671 $149K
New York State Common Retirement Fund 0.00% Reduce -39.7% 9,097 $140K
Los Angeles Capital Management LLC 0.00% New 5,409 $130K
KLP Kapitalforvaltning As 0.00% No change 6,800 $105K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% New 6,163 $95K
Ameritas Investment Partners, Inc. 0.00% No change 3,449 $53K
Russell Investments Group, Ltd. 0.00% Reduce -14.3% 3,121 $48K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +25.9% 2,884 $44K
Simplex Trading, LLC 0.00% Add +1467.5% 2,649 $41K
Tower Research Capital LLC (TRC) 0.00% Add +46.2% 2,304 $35K

"% of holder's portfolio" is ELVN's weight in each manager's 13F, not the share of Enliven Therapeutics Inc. the manager owns.

Show all 126 holders