Enliven TherapeuticsELVN
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 126 institutions reported holding Enliven Therapeutics Inc. (ELVN) in their 13F filings, down 8 from Q3 2025. 17 opened new positions and 26 sold out. The largest holders were Orbimed Advisors LLC ($122.6M), FMR LLC ($109.5M) and Commodore Capital LP ($72.3M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Enliven Therapeutics Inc.
- CUSIP
- 29337E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 17 | $25.7M |
| Exits | 26 | $58.9M |
All 13F filers, Q3 2025 → Q4 2025: 7,166,732 shares bought and 4,913,259 shares sold, net +2,253,473 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 126 holders
| Orbimed Advisors LLC | 2.51% | No change | 7,959,538 | $122.6M |
| FMR LLC | 0.01% | Reduce -0.3% | 7,107,635 | $109.5M |
| Commodore Capital LP | 4.81% | No change | 4,692,809 | $72.3M |
| Vestal Point Capital, LP | 2.16% | Add +230.2% | 3,830,000 | $59.0M |
| Fairmount Funds Management LLC | 4.35% | No change | 3,711,444 | $57.2M |
| BlackRock, Inc. | 0.00% | Add +2.7% | 3,613,326 | $55.6M |
| Polar Capital Holdings Plc | 0.25% | Add +13.5% | 3,513,680 | $54.1M |
| Venrock Adviser, LLC | 2.45% | No change | 3,226,331 | $49.7M |
| Vanguard Group Inc. | 0.00% | Add +9.7% | 2,801,665 | $43.1M |
| Janus Henderson Group PLC | 0.01% | Reduce -6.8% | 1,671,724 | $25.7M |
| Point72 Asset Management | 0.04% | Add +44.6% | 1,504,601 | $23.2M |
| Novo Holdings A/S | 1.77% | Add +3.8% | 1,480,000 | $22.8M |
| Citadel Advisors | 0.02% | Add +22.7% | 1,424,344 | $21.9M |
| Capital Research Global Investors | 0.00% | Reduce -0.8% | 1,304,346 | $20.1M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -6.8% | 1,303,235 | $20.1M |
| State Street Corp. | 0.00% | Add +9.1% | 1,052,862 | $16.2M |
| Geode Capital Management, LLC | 0.00% | Reduce -3.3% | 1,048,722 | $16.2M |
| Soleus Capital Management, L.P. | 0.67% | New | 1,025,000 | $15.8M |
| Blackstone Inc. | 0.06% | Reduce -27.7% | 954,946 | $14.7M |
| Rock Springs Capital Management LP | 0.63% | Add +16.4% | 798,405 | $12.3M |
| 5AM Venture Management, LLC | 3.74% | No change | 772,477 | $11.9M |
| Candriam S.C.A. | 0.03% | Reduce -25.7% | 453,019 | $7.0M |
| Spruce Street Capital LP | 2.27% | — | 446,084 | $6.9M |
| Morgan Stanley | 0.00% | Add +59.4% | 411,823 | $6.3M |
| Dimensional Fund Advisors LP | 0.00% | Add +148.6% | 398,893 | $6.1M |
| Marshall Wace, LLP | 0.01% | Add +9.2% | 371,906 | $5.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.2% | 355,192 | $5.5M |
| Northern Trust Corp. | 0.00% | Reduce -10.7% | 352,239 | $5.4M |
| Logos Global Management LP | 0.35% | No change | 340,000 | $5.2M |
| Patient Square Capital LP | 1.02% | Add +22.8% | 308,141 | $4.7M |
| Woodline Partners LP | 0.02% | Add +0.2% | 301,023 | $4.6M |
| Millennium Management | 0.00% | Reduce -22.1% | 296,947 | $4.6M |
| Baker Bros. Advisors LP | 0.02% | Add +136.3% | 271,406 | $4.2M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -9.6% | 237,204 | $3.7M |
| Sphera Funds Management LTD. | 0.73% | Add +36.0% | 226,765 | $3.5M |
| Exome Asset Management LLC | 1.69% | New | 222,308 | $3.4M |
| Trails Edge Capital Partners, LP | 0.76% | — | 199,306 | $3.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +459.9% | 194,735 | $3.0M |
| Avidity Partners Management LP | 0.62% | No change | 140,300 | $2.2M |
| Wellington Management Group LLP | 0.00% | Add +19.6% | 129,876 | $2.0M |
| Bank of New York Mellon Corp | 0.00% | Reduce -4.4% | 110,569 | $1.7M |
| Nuveen, LLC | 0.00% | Reduce -2.6% | 105,448 | $1.6M |
| Jane Street Group, LLC | 0.00% | New | 101,971 | $1.6M |
| Seven Fleet Capital Management LP | 1.04% | — | 99,953 | $1.5M |
| HighVista Strategies LLC | 0.33% | Reduce -68.2% | 82,536 | $1.3M |
| Barclays PLC | 0.00% | Reduce -1.1% | 69,875 | $1.1M |
| Lighthouse Investment Partners, LLC | 0.03% | New | 65,000 | $1.0M |
| Swiss National Bank | 0.00% | Add +1.7% | 64,273 | $990K |
| XTX Topco Ltd | 0.02% | Add +472.6% | 60,702 | $935K |
| ExodusPoint Capital Management, LP | 0.01% | Add +25.5% | 60,415 | $930K |
| UBS Group AG | 0.00% | Reduce -27.2% | 57,868 | $891K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +6.8% | 55,210 | $850K |
| Prelude Capital Management, LLC | 0.06% | New | 52,578 | $810K |
| Rhumbline Advisers | 0.00% | Reduce -16.0% | 50,509 | $778K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Add +53.6% | 48,741 | $751K |
| American Century Companies Inc. | 0.00% | Add +297.9% | 45,792 | $705K |
| Jump Financial, LLC | 0.01% | New | 45,354 | $698K |
| Wells Fargo & Company | 0.00% | Add +66.7% | 43,056 | $663K |
| Alliancebernstein L.P. | 0.00% | No change | 36,840 | $567K |
| Prudential Financial Inc. | 0.00% | New | 35,580 | $548K |
| Bank of America Corp. | 0.00% | Add +38.9% | 32,711 | $504K |
| California State Teachers Retirement System | 0.00% | Add +58.4% | 32,206 | $496K |
| Deutsche Bank AG | 0.00% | Add +24.7% | 31,420 | $484K |
| ADAR1 Capital Management, LLC | 0.03% | New | 30,000 | $462K |
| Tudor Investment Corporation | 0.00% | Add +82.0% | 29,673 | $457K |
| Aquatic Capital Management LLC | 0.01% | New | 27,955 | $431K |
| Legal & General Group Plc | 0.00% | Reduce -19.9% | 27,059 | $417K |
| Invesco Ltd. | 0.00% | Add +7.0% | 24,720 | $381K |
| MetLife Investment Management, LLC | 0.00% | No change | 24,556 | $378K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -89.7% | 23,800 | $367K |
| Squarepoint Ops LLC | 0.00% | Reduce -42.1% | 20,763 | $320K |
| JPMorgan Chase & Co. | 0.00% | Reduce -16.6% | 20,701 | $319K |
| State of Wisconsin Investment Board | 0.00% | Reduce -57.2% | 20,398 | $314K |
| Franklin Resources Inc. | 0.00% | Reduce -95.3% | 20,167 | $311K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -56.1% | 19,336 | $298K |
| Ameriprise Financial Inc. | 0.00% | Reduce -84.6% | 18,949 | $292K |
| Citigroup Inc. | 0.00% | Add +57.4% | 18,489 | $285K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -6.4% | 18,287 | $282K |
| Intech Investment Management LLC | 0.00% | Add +15.6% | 16,729 | $258K |
| Virtus Investment Advisers, LLC | 0.07% | Add +172.7% | 15,778 | $243K |
| Axq Capital, LP | 0.05% | New | 14,244 | $219K |
| SG Americas Securities, LLC | 0.00% | Reduce -36.9% | 14,035 | $216K |
| Fox Run Management, L.L.C. | 0.03% | New | 12,432 | $191K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +1.1% | 11,162 | $172K |
| Canada Pension Plan Investment Board | 0.00% | New | 10,800 | $166K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 10,480 | $161K |
| AlphaQuest LLC | 0.01% | Add +119.9% | 10,337 | $159K |
| Landscape Capital Management, L.L.C. | 0.01% | No change | 10,301 | $159K |
| Profund Advisors LLC | 0.00% | New | 10,179 | $157K |
| BNP Paribas Financial Markets | 0.00% | Add +5.8% | 9,672 | $149K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -6.9% | 9,671 | $149K |
| New York State Common Retirement Fund | 0.00% | Reduce -39.7% | 9,097 | $140K |
| Los Angeles Capital Management LLC | 0.00% | New | 5,409 | $130K |
| KLP Kapitalforvaltning As | 0.00% | No change | 6,800 | $105K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | New | 6,163 | $95K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,449 | $53K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -14.3% | 3,121 | $48K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +25.9% | 2,884 | $44K |
| Simplex Trading, LLC | 0.00% | Add +1467.5% | 2,649 | $41K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +46.2% | 2,304 | $35K |
"% of holder's portfolio" is ELVN's weight in each manager's 13F, not the share of Enliven Therapeutics Inc. the manager owns.