Enanta PharmaceuticalsENTA
13F holders, Q4 2025 (December 31)132holders +10
33new positions
24sold out
6famous investors
$15.77avg. 13F price*
At the end of Q4 2025, 132 institutions reported holding Enanta Pharmaceuticals Inc. (ENTA) in their 13F filings, up 10 from Q3 2025. 33 opened new positions and 24 sold out. The largest holders were Janus Henderson Group PLC ($58.8M), BlackRock, Inc. ($48.5M) and Farallon Capital Management, L.L.C. ($43.7M). 6 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Enanta Pharmaceuticals Inc.
- CUSIP
- 29251M106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $51.4M |
| Exits | 24 | $18.8M |
All 13F filers, Q3 2025 → Q4 2025: 9,520,485 shares bought and 2,464,311 shares sold, net +7,056,174 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 132 holders
| Janus Henderson Group PLC | 0.03% | Add +91.6% | 3,729,659 | $58.8M |
| BlackRock, Inc. | 0.00% | Add +67.8% | 3,076,282 | $48.5M |
| Farallon Capital Management, L.L.C. | 0.23% | Add +30.6% | 2,772,262 | $43.7M |
| Krensavage Asset Management, LLC | 15.41% | Add +30.8% | 2,766,390 | $43.6M |
| Vanguard Group Inc. | 0.00% | Add +18.7% | 2,301,794 | $36.3M |
| Deep Track Capital, LP | 0.70% | New | 1,956,867 | $30.9M |
| Acadian Asset Management LLC | 0.02% | Add +2.1% | 885,126 | $13.9M |
| Millennium Management | 0.01% | Reduce -29.3% | 670,428 | $10.6M |
| Geode Capital Management, LLC | 0.00% | Add +30.9% | 645,791 | $10.2M |
| Renaissance Technologies | 0.02% | Add +33.9% | 642,200 | $10.1M |
| State Street Corp. | 0.00% | Add +11.0% | 523,715 | $8.3M |
| Point72 Asset Management | 0.01% | Add +46.3% | 438,939 | $6.9M |
| Hillsdale Investment Management Inc. | 0.18% | New | 422,300 | $6.7M |
| Spruce Street Capital LP | 2.03% | — | 389,687 | $6.1M |
| Marshall Wace, LLP | 0.01% | Add +39.9% | 385,276 | $6.1M |
| Morgan Stanley | 0.00% | Add +20.3% | 339,918 | $5.4M |
| Two Sigma Investments, LP | 0.01% | Add +370.1% | 285,448 | $4.5M |
| Invesco Ltd. | 0.00% | Add +325.2% | 253,811 | $4.0M |
| AQR Capital Management | 0.00% | Add +3.5% | 234,835 | $3.7M |
| Northern Trust Corp. | 0.00% | Add +17.4% | 229,889 | $3.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +31.5% | 218,816 | $3.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +31.3% | 218,636 | $3.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -21.6% | 211,614 | $3.3M |
| D. E. Shaw & Co. | 0.00% | Reduce -25.7% | 167,714 | $2.6M |
| Two Sigma Advisers, LP | 0.00% | Add +14.6% | 143,300 | $2.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.8% | 112,964 | $1.8M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +34.1% | 103,903 | $1.6M |
| Stonepine Capital Management, LLC | 1.25% | Reduce -67.2% | 100,000 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +404.0% | 99,884 | $1.6M |
| Sei Investments Co. | 0.00% | Add +33.8% | 98,782 | $1.6M |
| Citadel Advisors | 0.00% | New | 93,158 | $1.5M |
| Nuveen, LLC | 0.00% | Reduce -47.8% | 86,056 | $1.4M |
| Opaleye Management Inc. | 0.16% | New | 75,000 | $1.2M |
| Bank of New York Mellon Corp | 0.00% | Add +20.0% | 72,588 | $1.1M |
| PDT Partners, LLC | 0.07% | Reduce -19.6% | 69,197 | $1.1M |
| Panagora Asset Management Inc. | 0.00% | New | 66,990 | $1.1M |
| Bank of America Corp. | 0.00% | Add +120.3% | 65,978 | $1.0M |
| Squarepoint Ops LLC | 0.00% | New | 65,966 | $1.0M |
| Diadema Partners LP | 0.61% | New | 65,138 | $1.0M |
| Wellington Management Group LLP | 0.00% | New | 63,219 | $997K |
| Barclays PLC | 0.00% | Add +32.1% | 54,989 | $867K |
| Campbell & CO Investment Adviser LLC | 0.04% | Add +187.2% | 54,149 | $854K |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 52,728 | $832K |
| Susquehanna Fundamental Investments, LLC | 0.03% | No change | 50,434 | $795K |
| Assenagon Asset Management S.A. | 0.00% | Reduce -15.4% | 45,877 | $723K |
| Man Group plc | 0.00% | Add +9.2% | 43,847 | $691K |
| ADAR1 Capital Management, LLC | 0.05% | New | 41,357 | $652K |
| Informed Momentum Co LLC | 0.07% | New | 40,952 | $646K |
| Prudential Financial Inc. | 0.00% | New | 40,015 | $631K |
| Sio Capital Management, LLC | 0.10% | New | 40,000 | $631K |
| Bank of Montreal | 0.00% | Add +10.7% | 37,484 | $591K |
| Ieq Capital, LLC | 0.00% | Reduce -3.5% | 36,385 | $574K |
| American Century Companies Inc. | 0.00% | Reduce -30.5% | 33,764 | $532K |
| Alliancebernstein L.P. | 0.00% | No change | 33,740 | $532K |
| Quantinno Capital Management LP | 0.00% | Reduce -9.8% | 33,495 | $528K |
| State of Wyoming | 0.06% | New | 32,887 | $519K |
| Franklin Resources Inc. | 0.00% | New | 32,720 | $516K |
| Qube Research & Technologies Ltd | 0.00% | Add +171.7% | 32,389 | $511K |
| Wells Fargo & Company | 0.00% | Add +96.9% | 30,716 | $484K |
| Hudson Bay Capital Management LP | 0.00% | New | 30,000 | $473K |
| Bridgeway Capital Management, LLC | 0.01% | No change | 29,700 | $468K |
| Rhumbline Advisers | 0.00% | Reduce -6.7% | 28,849 | $455K |
| Thrivent Financial for Lutherans | 0.00% | Reduce -16.6% | 28,376 | $448K |
| Portland Global Advisors LLC | 0.04% | No change | 24,275 | $383K |
| Deutsche Bank AG | 0.00% | Add +4.6% | 24,107 | $380K |
| Headlands Technologies LLC | 0.03% | New | 22,596 | $356K |
| Cwm, LLC | 0.00% | Add +0.1% | 20,666 | $326K |
| State of Wisconsin Investment Board | 0.00% | New | 18,608 | $293K |
| Persistent Asset Partners Ltd | 0.13% | New | 17,466 | $275K |
| T. Rowe Price Associates Inc. | 0.00% | Add +42.0% | 14,410 | $228K |
| MetLife Investment Management, LLC | 0.00% | Add +119.7% | 14,408 | $227K |
| AlphaQuest LLC | 0.01% | Add +39.0% | 14,178 | $224K |
| Virtu Financial LLC | 0.01% | New | 13,967 | $220K |
| Jump Financial, LLC | 0.00% | New | 13,900 | $219K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +30.5% | 12,668 | $200K |
| Jain Global LLC | 0.00% | New | 12,543 | $198K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -30.2% | 11,483 | $182K |
| Kingsview Wealth Management, LLC | 0.00% | New | 10,653 | $168K |
| Susquehanna International Group, LLP | 0.00% | Reduce -91.1% | 10,467 | $165K |
| Fox Run Management, L.L.C. | 0.02% | New | 10,182 | $161K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +0.7% | 10,721 | $146K |
| Canada Pension Plan Investment Board | 0.00% | New | 8,900 | $140K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 6,676 | $105K |
| New York State Common Retirement Fund | 0.00% | Reduce -21.9% | 6,071 | $96K |
| UBS Group AG | 0.00% | Reduce -66.7% | 5,092 | $80K |
| Clearstead Trust, LLC | 0.01% | No change | 5,064 | $80K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -46.2% | 4,703 | $74K |
| FMR LLC | 0.00% | Add +141.6% | 4,312 | $68K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +333.9% | 3,584 | $57K |
| STRS Ohio | 0.00% | New | 3,200 | $50K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 2,529 | $40K |
| Legal & General Group Plc | 0.00% | Add +43.1% | 2,438 | $38K |
| Seven Fleet Capital Management LP | 0.02% | — | 2,270 | $36K |
| Meeder Asset Management Inc. | 0.00% | New | 2,025 | $32K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,973 | $31K |
| California State Teachers Retirement System | 0.00% | Add +33.7% | 1,679 | $26K |
| Sterling Capital Management LLC | 0.00% | Add +13.0% | 1,572 | $25K |
| Essential Partners LLC | 0.01% | No change | 1,516 | $24K |
| Versant Capital Management, Inc | 0.00% | No change | 1,424 | $22K |
| Citigroup Inc. | 0.00% | Reduce -32.4% | 1,422 | $22K |
| GAMMA Investing LLC | 0.00% | No change | 1,331 | $21K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 1,148 | $18K |
| Simplex Trading, LLC | 0.00% | Add +8.8% | 922 | $15K |
| Amalgamated Bank | 0.00% | Add +28.5% | 857 | $14K |
| Royal Bank of Canada | 0.00% | Reduce -25.5% | 880 | $13K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -1.5% | 786 | $12K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -61.5% | 721 | $11K |
| True Wealth Design, LLC | 0.00% | No change | 645 | $10K |
| GF Fund Management Co. LTD. | 0.00% | Add +26.1% | 565 | $9K |
| Rockefeller Capital Management L.P. | 0.00% | New | 514 | $8K |
| Smartleaf Asset Management LLC | 0.00% | No change | 410 | $7K |
| IFP Advisors, Inc | 0.00% | No change | 396 | $6K |
| Comerica Bank | 0.00% | No change | 367 | $6K |
| Red Tortoise LLC | 0.00% | No change | 364 | $6K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -60.0% | 340 | $5K |
| Optiver Holding B.V. | 0.00% | No change | 258 | $4K |
| Rothschild Investment LLC | 0.00% | Reduce -4.5% | 253 | $4K |
| Allworth Financial LP | 0.00% | Reduce -2.1% | 228 | $4K |
| Johnson Financial Group, Inc. | 0.00% | No change | 188 | $3K |
| Farther Finance Advisors, LLC | 0.00% | No change | 169 | $3K |
| Daiwa Securities Group Inc. | 0.00% | New | 96 | $2K |
| Torren Management, LLC | 0.00% | — | 120 | $2K |
| Parkside Financial Bank & Trust | 0.00% | No change | 71 | $1K |
| Los Angeles Capital Management LLC | 0.00% | New | 103 | $1K |
| Sunbelt Securities, Inc. | 0.00% | No change | 63 | $994 |
| Parallel Advisors, LLC | 0.00% | New | 51 | $804 |
| Osaic Holdings, Inc. | 0.00% | Reduce -79.5% | 18 | $284 |
| Raffa Wealth Management, LLC | 0.00% | No change | 11 | $173 |
| MAI Capital Management | 0.00% | New | 7 | $111 |
| Arax Advisory Partners | 0.00% | Reduce -99.9% | 6 | $95 |
| SBI Securities Co., Ltd. | 0.00% | No change | 1 | $16 |
| Covestor Ltd | 0.00% | Reduce -6.3% | 15 | $0 |
"% of holder's portfolio" is ENTA's weight in each manager's 13F, not the share of Enanta Pharmaceuticals Inc. the manager owns.