Eton PharmaceuticalsETON

13F holders, Q2 2026 (June 30)
164holders +48
53new positions
5sold out
5famous investors
$36.19avg. 13F price*

At the end of Q2 2026, 164 institutions reported holding Eton Pharmaceuticals Inc. (ETON) in their 13F filings, up 48 from Q1 2026. 53 opened new positions and 5 sold out. The largest holders were Opaleye Management Inc. ($103.5M), EcoR1 Capital, LLC ($78.6M) and BlackRock, Inc. ($68.6M). 5 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Eton Pharmaceuticals Inc.
CUSIP
29772L108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 44Q1 2024Q2 2024: 45Q2 2024Q3 2024: 48Q3 2024Q4 2024: 71Q4 2024Q1 2025: 86Q1 2025Q2 2025: 87Q2 2025Q3 2025: 103Q3 2025Q4 2025: 104Q4 2025Q1 2026: 116Q1 2026Q2 2026: 164Q2 2026

Total Exit/New Position Q1 2026 → Q2 2026

InstitutionsTotal Value
New Positions53$37.9M
Exits5$5.5M

All 13F filers, Q1 2026 → Q2 2026: 3,258,659 shares bought and 1,247,314 shares sold, net +2,011,345 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 164 holders

Opaleye Management Inc. 9.38% No change 2,860,000 $103.5M
EcoR1 Capital, LLC 3.90% No change 2,171,938 $78.6M
BlackRock, Inc. 0.00% Add +10.4% 1,895,833 $68.6M
Nantahala Capital Management, LLC 2.58% No change 1,175,951 $42.6M
Vanguard Capital Management LLC 0.00% Reduce -1.8% 976,570 $35.4M
Morgan Stanley 0.00% Add +60.7% 767,972 $27.8M
State Street Corp. 0.00% Add +32.4% 701,786 $25.4M
Geode Capital Management, LLC 0.00% Add +12.9% 652,303 $23.6M
Oberweis Asset Management Inc./ 0.38% Add +14.2% 501,600 $18.2M
National Philanthropic Trust 0.26% No change 492,112 $17.8M
Westside Investment Management, Inc. 2.05% Reduce -7.9% 431,160 $15.6M
Pillsbury Lake Capital LLC 3.85% Add +6.1% 387,157 $14.0M
Nuveen, LLC 0.00% Add +548.3% 375,707 $13.6M
BNP Paribas Financial Markets 0.01% Add +6.7% 322,466 $11.7M
Woodline Partners LP 0.03% Add +82.1% 310,879 $11.3M
Thompson Siegel & Walmsley LLC 0.19% Reduce -26.8% 297,232 $10.8M
Northern Trust Corp. 0.00% Add +7.6% 255,849 $9.3M
Marshall Wace, LLP 0.01% Add +201.2% 249,182 $9.0M
Panoramic Capital, LLC 3.24% Add +12.5% 208,192 $7.5M
Vanguard Portfolio Management LLC 0.00% Add +28.2% 194,591 $7.0M
JPMorgan Chase & Co. 0.00% Add +12.8% 191,635 $7.0M
D. E. Shaw & Co. 0.00% New 188,452 $6.8M
Jane Street Group, LLC 0.00% Add +94.6% 185,697 $6.7M
Lumbard & Kellner, LLC 1.93% Reduce 0.0% 175,909 $6.4M
Cannell Capital LLC 4.32% Reduce -50.1% 170,747 $6.2M
Norges Bank 0.00% — 169,500 $6.1M
Vanguard Fiduciary Trust Co. 0.00% Add +2.3% 168,539 $6.1M
Informed Momentum Co LLC 0.51% Add +225.0% 158,045 $5.7M
Prospect Capital Advisors, LLC 2.58% New 157,200 $5.7M
Aristides Capital LLC 1.35% Reduce -21.8% 145,410 $5.3M
Bank of America Corp. 0.00% Reduce -1.5% 142,257 $5.1M
Prelude Capital Management, LLC 0.37% Reduce -27.1% 137,572 $5.0M
Goldman Sachs Group Inc. 0.00% Reduce -39.0% 132,583 $4.8M
Bank of New York Mellon Corp 0.00% Add +6.3% 118,249 $4.3M
Two Sigma Investments, LP 0.00% Add +9.3% 116,291 $4.2M
Wells Fargo & Company 0.00% Add +1099.5% 114,655 $4.2M
Wasatch Advisors LP 0.02% New 92,742 $3.4M
Bridge City Capital, LLC 0.73% Add +316.7% 88,132 $3.2M
Walleye Capital LLC 0.02% Add +5.2% 86,249 $3.1M
Charles Schwab Investment Management Inc. 0.00% Add +12.0% 77,032 $2.8M
Wellington Management Group LLP 0.00% Add +8.5% 76,103 $2.8M
Diametric Capital, LP 0.28% Reduce -53.4% 73,101 $2.6M
Numerai GP LLC 0.21% Add +87.7% 70,114 $2.5M
UBS Group AG 0.00% Reduce -61.3% 65,424 $2.4M
Squarepoint Ops LLC 0.00% New 59,562 $2.2M
Boothbay Fund Management, LLC 0.04% Add +3.4% 57,516 $2.1M
Barclays PLC 0.00% Add +13.8% 56,181 $2.0M
HighTower Advisors, LLC 0.00% Add +187.2% 52,907 $1.9M
Renaissance Technologies 0.00% Reduce -68.0% 52,300 $1.9M
Citadel Advisors 0.00% Reduce -54.6% 48,969 $1.8M
Polen Capital Management LLC 0.01% Add +50.6% 45,379 $1.6M
Point72 Asset Management 0.00% New 44,918 $1.6M
Aquatic Capital Management LLC 0.05% Add +263.1% 43,794 $1.6M
Dimensional Fund Advisors LP 0.00% New 42,484 $1.5M
HSBC Holdings PLC 0.00% New 40,974 $1.5M
Anchor Capital Advisors LLC 0.04% Reduce -0.6% 40,619 $1.5M
Sei Investments Co. 0.00% Reduce -40.2% 34,698 $1.3M
Jefferies Financial Group Inc. 0.01% New 34,027 $1.2M
Rhumbline Advisers 0.00% Add +9.7% 33,703 $1.2M
Y-Intercept (Hong Kong) Ltd 0.02% New 33,542 $1.2M
Invesco Ltd. 0.00% Add +46.0% 33,384 $1.2M
New York State Common Retirement Fund 0.00% Add +304.7% 32,779 $1.2M
Blair William & Co. 0.00% Add +0.1% 32,419 $1.2M
Riggs Asset Managment Co. Inc. 0.21% New 32,046 $1.2M
Sigma Planning Corp 0.03% New 30,000 $1.1M
American Century Companies Inc. 0.00% Add +144.2% 29,125 $1.1M
Juncture Wealth Strategies, LLC 0.27% Add +50.4% 28,849 $1.0M
Deutsche Bank AG 0.00% Add +25.5% 26,522 $960K
STRS Ohio 0.00% New 23,600 $854K
Guilbault Capital LLC 0.85% Add +1.0% 23,460 $849K
T. Rowe Price Associates Inc. 0.00% Add +24.3% 21,932 $794K
Prudential Financial Inc. 0.00% New 21,133 $765K
Citigroup Inc. 0.00% Add +722.3% 20,952 $758K
Essex Investment Management Co. LLC 0.10% Reduce -0.3% 20,131 $729K
State of Wisconsin Investment Board 0.00% Add +4.8% 19,544 $707K
First Trust Advisors LP 0.00% New 19,477 $705K
Alliancebernstein L.P. 0.00% New 28,250 $697K
Navellier & Associates Inc. 0.05% New 18,010 $652K
Bank of Nova Scotia 0.00% Add +14.7% 17,200 $623K
CHICAGO TRUST Co NA 0.09% No change 16,700 $605K
Man Group plc 0.00% New 16,152 $585K
Gotham Asset Management 0.00% New 15,982 $579K
Los Angeles Capital Management LLC 0.00% Add +52.6% 15,675 $567K
MetLife Investment Management, LLC 0.00% Add +0.9% 15,673 $567K
Acadian Asset Management LLC 0.00% New 15,013 $541K
PDT Partners, LLC 0.03% No change 14,891 $539K
Susquehanna International Group, LLP 0.00% Reduce -57.4% 14,505 $525K
Vanguard Global Advisers, LLC 0.00% Add +57.5% 14,165 $513K
LPL Financial LLC 0.00% New 14,017 $507K
Connor, Clark & Lunn Investment Management Ltd. 0.00% Reduce -69.2% 13,150 $476K
Raymond James Financial Inc. 0.00% Add +1.6% 12,444 $450K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +2.1% 12,296 $445K
Legato Capital Management LLC 0.03% New 11,521 $417K
Quantum Private Wealth, LLC 0.11% No change 11,500 $416K
Menard Financial Group LLC 0.21% New 10,642 $385K
&partners 0.00% New 10,000 $362K
Mackenzie Financial Corp. 0.00% New 9,590 $347K
Envestnet Asset Management Inc. 0.00% Reduce -10.8% 9,582 $347K
BRC Group Holdings, Inc. 0.08% New 9,383 $340K
Virtu Financial LLC 0.01% New 9,102 $329K
Granite Investment Partners, LLC 0.02% No change 8,479 $307K
Russell Investments Group, Ltd. 0.00% Add +205.9% 8,167 $296K
Brevan Howard Capital Management LP 0.00% Reduce -64.7% 7,955 $288K
Canada Pension Plan Investment Board 0.00% New 7,900 $286K
Mutual Advisors, LLC 0.01% New 7,561 $274K
Intech Investment Management LLC 0.00% New 7,423 $269K
Voleon Capital Management LP 0.00% Reduce -45.6% 7,227 $262K
Jain Global LLC 0.00% Reduce -12.9% 7,221 $261K
Police & Firemen's Retirement System of New Jersey 0.00% No change 7,209 $261K
Legal & General Group Plc 0.00% Add +206.1% 7,131 $258K
Manufacturers Life Insurance Company, The 0.00% New 6,996 $253K
State of Alaska, Department of Revenue 0.00% No change 6,943 $250K
Quantinno Capital Management LP 0.00% New 6,661 $241K
Profund Advisors LLC 0.01% New 6,534 $237K
Anchyra Partners LLC 0.05% New 6,081 $220K
XTX Topco Ltd 0.00% Reduce -88.5% 5,965 $216K
Northwestern Mutual Wealth Management Co. 0.00% Reduce -25.0% 5,625 $204K
BankChampaign, National Association 0.16% New 5,590 $202K
Quantbot Technologies LP 0.01% Reduce -41.6% 4,550 $165K
China Universal Asset Management Co., Ltd. 0.01% Reduce -8.4% 4,360 $158K
Kemnay Advisory Services Inc. 0.02% New 3,716 $135K
State of Wyoming 0.01% Reduce -68.9% 2,950 $107K
Persistent Asset Partners Ltd 0.03% New 2,493 $90K
Ameritas Investment Partners, Inc. 0.00% Add +11.8% 2,423 $88K
New York State Teachers Retirement System 0.00% New 2,334 $84K
FMR LLC 0.00% Add +39.9% 2,125 $77K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -12.4% 1,225 $44K
Toth Financial Advisory Corp. 0.00% New 1,200 $43K
Truvestments Capital LLC 0.01% No change 1,183 $43K
Caitong International Asset Management Co., Ltd 0.00% Add +3408.3% 842 $30K
Royal Bank of Canada 0.00% Add +6138.5% 811 $29K
SBI Securities Co., Ltd. 0.00% Add +171.9% 715 $26K
Tower Research Capital LLC (TRC) 0.00% Reduce -38.4% 712 $26K
GF Fund Management Co. LTD. 0.00% Reduce -4.7% 569 $21K
Federated Hermes, Inc. 0.00% New 474 $17K
Nisa Investment Advisors, LLC 0.00% New 438 $16K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% No change 368 $13K
California State Teachers Retirement System 0.00% Reduce -74.1% 360 $13K
Osaic Holdings, Inc. 0.00% Add +56.5% 313 $11K
Parallel Advisors, LLC 0.00% No change 303 $11K
Jones Financial Companies LLLP 0.00% Reduce -28.3% 251 $9K
Pinnacle Wealth Planning Services, Inc. 0.00% New 212 $8K
Group One Trading LLC 0.00% New 155 $6K
Farther Finance Advisors, LLC 0.00% No change 123 $5K
Sterling Capital Management LLC 0.00% Reduce -43.7% 94 $3K
Institute for Wealth Management, LLC. 0.00% New 73 $3K
Versant Capital Management, Inc 0.00% New 61 $2K
MassMutual Private Wealth & Trust, FSB 0.00% New 52 $2K
PNC Financial Services Group, Inc. 0.00% Reduce -76.5% 42 $2K
Aster Capital Management (DIFC) Ltd 0.00% New 35 $1K
Investors Portfolio Services LLC 0.00% No change 34 $1K
Keating Financial Advisory Services, Inc. 0.00% Add +3300.0% 34 $1K
Hughes Financial Services, LLC 0.00% Add +26.9% 33 $1K
Covestor Ltd 0.00% Reduce -42.9% 16 $1K
Quarry LP 0.00% New 26 $941
Allworth Financial LP 0.00% New 23 $833
GAMMA Investing LLC 0.00% No change 21 $760
US Bancorp \de 0.00% No change 19 $688
Larson Financial Group LLC 0.00% New 11 $398
Arax Advisory Partners 0.00% New 10 $362
EverSource Wealth Advisors, LLC 0.00% Reduce -76.3% 9 $326
National Bank of Canada 0.00% New 4 $144
Rothschild Investment LLC 0.00% New 1 $36
Essential Partners LLC 0.00% New 1 $36

"% of holder's portfolio" is ETON's weight in each manager's 13F, not the share of Eton Pharmaceuticals Inc. the manager owns.