Eton PharmaceuticalsETON
13F holders, Q2 2026 (June 30)At the end of Q2 2026, 164 institutions reported holding Eton Pharmaceuticals Inc. (ETON) in their 13F filings, up 48 from Q1 2026. 53 opened new positions and 5 sold out. The largest holders were Opaleye Management Inc. ($103.5M), EcoR1 Capital, LLC ($78.6M) and BlackRock, Inc. ($68.6M). 5 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Eton Pharmaceuticals Inc.
- CUSIP
- 29772L108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 53 | $37.9M |
| Exits | 5 | $5.5M |
All 13F filers, Q1 2026 → Q2 2026: 3,258,659 shares bought and 1,247,314 shares sold, net +2,011,345 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 164 holders
| Opaleye Management Inc. | 9.38% | No change | 2,860,000 | $103.5M |
| EcoR1 Capital, LLC | 3.90% | No change | 2,171,938 | $78.6M |
| BlackRock, Inc. | 0.00% | Add +10.4% | 1,895,833 | $68.6M |
| Nantahala Capital Management, LLC | 2.58% | No change | 1,175,951 | $42.6M |
| Vanguard Capital Management LLC | 0.00% | Reduce -1.8% | 976,570 | $35.4M |
| Morgan Stanley | 0.00% | Add +60.7% | 767,972 | $27.8M |
| State Street Corp. | 0.00% | Add +32.4% | 701,786 | $25.4M |
| Geode Capital Management, LLC | 0.00% | Add +12.9% | 652,303 | $23.6M |
| Oberweis Asset Management Inc./ | 0.38% | Add +14.2% | 501,600 | $18.2M |
| National Philanthropic Trust | 0.26% | No change | 492,112 | $17.8M |
| Westside Investment Management, Inc. | 2.05% | Reduce -7.9% | 431,160 | $15.6M |
| Pillsbury Lake Capital LLC | 3.85% | Add +6.1% | 387,157 | $14.0M |
| Nuveen, LLC | 0.00% | Add +548.3% | 375,707 | $13.6M |
| BNP Paribas Financial Markets | 0.01% | Add +6.7% | 322,466 | $11.7M |
| Woodline Partners LP | 0.03% | Add +82.1% | 310,879 | $11.3M |
| Thompson Siegel & Walmsley LLC | 0.19% | Reduce -26.8% | 297,232 | $10.8M |
| Northern Trust Corp. | 0.00% | Add +7.6% | 255,849 | $9.3M |
| Marshall Wace, LLP | 0.01% | Add +201.2% | 249,182 | $9.0M |
| Panoramic Capital, LLC | 3.24% | Add +12.5% | 208,192 | $7.5M |
| Vanguard Portfolio Management LLC | 0.00% | Add +28.2% | 194,591 | $7.0M |
| JPMorgan Chase & Co. | 0.00% | Add +12.8% | 191,635 | $7.0M |
| D. E. Shaw & Co. | 0.00% | New | 188,452 | $6.8M |
| Jane Street Group, LLC | 0.00% | Add +94.6% | 185,697 | $6.7M |
| Lumbard & Kellner, LLC | 1.93% | Reduce 0.0% | 175,909 | $6.4M |
| Cannell Capital LLC | 4.32% | Reduce -50.1% | 170,747 | $6.2M |
| Norges Bank | 0.00% | — | 169,500 | $6.1M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +2.3% | 168,539 | $6.1M |
| Informed Momentum Co LLC | 0.51% | Add +225.0% | 158,045 | $5.7M |
| Prospect Capital Advisors, LLC | 2.58% | New | 157,200 | $5.7M |
| Aristides Capital LLC | 1.35% | Reduce -21.8% | 145,410 | $5.3M |
| Bank of America Corp. | 0.00% | Reduce -1.5% | 142,257 | $5.1M |
| Prelude Capital Management, LLC | 0.37% | Reduce -27.1% | 137,572 | $5.0M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -39.0% | 132,583 | $4.8M |
| Bank of New York Mellon Corp | 0.00% | Add +6.3% | 118,249 | $4.3M |
| Two Sigma Investments, LP | 0.00% | Add +9.3% | 116,291 | $4.2M |
| Wells Fargo & Company | 0.00% | Add +1099.5% | 114,655 | $4.2M |
| Wasatch Advisors LP | 0.02% | New | 92,742 | $3.4M |
| Bridge City Capital, LLC | 0.73% | Add +316.7% | 88,132 | $3.2M |
| Walleye Capital LLC | 0.02% | Add +5.2% | 86,249 | $3.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +12.0% | 77,032 | $2.8M |
| Wellington Management Group LLP | 0.00% | Add +8.5% | 76,103 | $2.8M |
| Diametric Capital, LP | 0.28% | Reduce -53.4% | 73,101 | $2.6M |
| Numerai GP LLC | 0.21% | Add +87.7% | 70,114 | $2.5M |
| UBS Group AG | 0.00% | Reduce -61.3% | 65,424 | $2.4M |
| Squarepoint Ops LLC | 0.00% | New | 59,562 | $2.2M |
| Boothbay Fund Management, LLC | 0.04% | Add +3.4% | 57,516 | $2.1M |
| Barclays PLC | 0.00% | Add +13.8% | 56,181 | $2.0M |
| HighTower Advisors, LLC | 0.00% | Add +187.2% | 52,907 | $1.9M |
| Renaissance Technologies | 0.00% | Reduce -68.0% | 52,300 | $1.9M |
| Citadel Advisors | 0.00% | Reduce -54.6% | 48,969 | $1.8M |
| Polen Capital Management LLC | 0.01% | Add +50.6% | 45,379 | $1.6M |
| Point72 Asset Management | 0.00% | New | 44,918 | $1.6M |
| Aquatic Capital Management LLC | 0.05% | Add +263.1% | 43,794 | $1.6M |
| Dimensional Fund Advisors LP | 0.00% | New | 42,484 | $1.5M |
| HSBC Holdings PLC | 0.00% | New | 40,974 | $1.5M |
| Anchor Capital Advisors LLC | 0.04% | Reduce -0.6% | 40,619 | $1.5M |
| Sei Investments Co. | 0.00% | Reduce -40.2% | 34,698 | $1.3M |
| Jefferies Financial Group Inc. | 0.01% | New | 34,027 | $1.2M |
| Rhumbline Advisers | 0.00% | Add +9.7% | 33,703 | $1.2M |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 33,542 | $1.2M |
| Invesco Ltd. | 0.00% | Add +46.0% | 33,384 | $1.2M |
| New York State Common Retirement Fund | 0.00% | Add +304.7% | 32,779 | $1.2M |
| Blair William & Co. | 0.00% | Add +0.1% | 32,419 | $1.2M |
| Riggs Asset Managment Co. Inc. | 0.21% | New | 32,046 | $1.2M |
| Sigma Planning Corp | 0.03% | New | 30,000 | $1.1M |
| American Century Companies Inc. | 0.00% | Add +144.2% | 29,125 | $1.1M |
| Juncture Wealth Strategies, LLC | 0.27% | Add +50.4% | 28,849 | $1.0M |
| Deutsche Bank AG | 0.00% | Add +25.5% | 26,522 | $960K |
| STRS Ohio | 0.00% | New | 23,600 | $854K |
| Guilbault Capital LLC | 0.85% | Add +1.0% | 23,460 | $849K |
| T. Rowe Price Associates Inc. | 0.00% | Add +24.3% | 21,932 | $794K |
| Prudential Financial Inc. | 0.00% | New | 21,133 | $765K |
| Citigroup Inc. | 0.00% | Add +722.3% | 20,952 | $758K |
| Essex Investment Management Co. LLC | 0.10% | Reduce -0.3% | 20,131 | $729K |
| State of Wisconsin Investment Board | 0.00% | Add +4.8% | 19,544 | $707K |
| First Trust Advisors LP | 0.00% | New | 19,477 | $705K |
| Alliancebernstein L.P. | 0.00% | New | 28,250 | $697K |
| Navellier & Associates Inc. | 0.05% | New | 18,010 | $652K |
| Bank of Nova Scotia | 0.00% | Add +14.7% | 17,200 | $623K |
| CHICAGO TRUST Co NA | 0.09% | No change | 16,700 | $605K |
| Man Group plc | 0.00% | New | 16,152 | $585K |
| Gotham Asset Management | 0.00% | New | 15,982 | $579K |
| Los Angeles Capital Management LLC | 0.00% | Add +52.6% | 15,675 | $567K |
| MetLife Investment Management, LLC | 0.00% | Add +0.9% | 15,673 | $567K |
| Acadian Asset Management LLC | 0.00% | New | 15,013 | $541K |
| PDT Partners, LLC | 0.03% | No change | 14,891 | $539K |
| Susquehanna International Group, LLP | 0.00% | Reduce -57.4% | 14,505 | $525K |
| Vanguard Global Advisers, LLC | 0.00% | Add +57.5% | 14,165 | $513K |
| LPL Financial LLC | 0.00% | New | 14,017 | $507K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Reduce -69.2% | 13,150 | $476K |
| Raymond James Financial Inc. | 0.00% | Add +1.6% | 12,444 | $450K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.1% | 12,296 | $445K |
| Legato Capital Management LLC | 0.03% | New | 11,521 | $417K |
| Quantum Private Wealth, LLC | 0.11% | No change | 11,500 | $416K |
| Menard Financial Group LLC | 0.21% | New | 10,642 | $385K |
| &partners | 0.00% | New | 10,000 | $362K |
| Mackenzie Financial Corp. | 0.00% | New | 9,590 | $347K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -10.8% | 9,582 | $347K |
| BRC Group Holdings, Inc. | 0.08% | New | 9,383 | $340K |
| Virtu Financial LLC | 0.01% | New | 9,102 | $329K |
| Granite Investment Partners, LLC | 0.02% | No change | 8,479 | $307K |
| Russell Investments Group, Ltd. | 0.00% | Add +205.9% | 8,167 | $296K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -64.7% | 7,955 | $288K |
| Canada Pension Plan Investment Board | 0.00% | New | 7,900 | $286K |
| Mutual Advisors, LLC | 0.01% | New | 7,561 | $274K |
| Intech Investment Management LLC | 0.00% | New | 7,423 | $269K |
| Voleon Capital Management LP | 0.00% | Reduce -45.6% | 7,227 | $262K |
| Jain Global LLC | 0.00% | Reduce -12.9% | 7,221 | $261K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 7,209 | $261K |
| Legal & General Group Plc | 0.00% | Add +206.1% | 7,131 | $258K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 6,996 | $253K |
| State of Alaska, Department of Revenue | 0.00% | No change | 6,943 | $250K |
| Quantinno Capital Management LP | 0.00% | New | 6,661 | $241K |
| Profund Advisors LLC | 0.01% | New | 6,534 | $237K |
| Anchyra Partners LLC | 0.05% | New | 6,081 | $220K |
| XTX Topco Ltd | 0.00% | Reduce -88.5% | 5,965 | $216K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -25.0% | 5,625 | $204K |
| BankChampaign, National Association | 0.16% | New | 5,590 | $202K |
| Quantbot Technologies LP | 0.01% | Reduce -41.6% | 4,550 | $165K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -8.4% | 4,360 | $158K |
| Kemnay Advisory Services Inc. | 0.02% | New | 3,716 | $135K |
| State of Wyoming | 0.01% | Reduce -68.9% | 2,950 | $107K |
| Persistent Asset Partners Ltd | 0.03% | New | 2,493 | $90K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +11.8% | 2,423 | $88K |
| New York State Teachers Retirement System | 0.00% | New | 2,334 | $84K |
| FMR LLC | 0.00% | Add +39.9% | 2,125 | $77K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -12.4% | 1,225 | $44K |
| Toth Financial Advisory Corp. | 0.00% | New | 1,200 | $43K |
| Truvestments Capital LLC | 0.01% | No change | 1,183 | $43K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +3408.3% | 842 | $30K |
| Royal Bank of Canada | 0.00% | Add +6138.5% | 811 | $29K |
| SBI Securities Co., Ltd. | 0.00% | Add +171.9% | 715 | $26K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -38.4% | 712 | $26K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -4.7% | 569 | $21K |
| Federated Hermes, Inc. | 0.00% | New | 474 | $17K |
| Nisa Investment Advisors, LLC | 0.00% | New | 438 | $16K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | No change | 368 | $13K |
| California State Teachers Retirement System | 0.00% | Reduce -74.1% | 360 | $13K |
| Osaic Holdings, Inc. | 0.00% | Add +56.5% | 313 | $11K |
| Parallel Advisors, LLC | 0.00% | No change | 303 | $11K |
| Jones Financial Companies LLLP | 0.00% | Reduce -28.3% | 251 | $9K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 212 | $8K |
| Group One Trading LLC | 0.00% | New | 155 | $6K |
| Farther Finance Advisors, LLC | 0.00% | No change | 123 | $5K |
| Sterling Capital Management LLC | 0.00% | Reduce -43.7% | 94 | $3K |
| Institute for Wealth Management, LLC. | 0.00% | New | 73 | $3K |
| Versant Capital Management, Inc | 0.00% | New | 61 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 52 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -76.5% | 42 | $2K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 35 | $1K |
| Investors Portfolio Services LLC | 0.00% | No change | 34 | $1K |
| Keating Financial Advisory Services, Inc. | 0.00% | Add +3300.0% | 34 | $1K |
| Hughes Financial Services, LLC | 0.00% | Add +26.9% | 33 | $1K |
| Covestor Ltd | 0.00% | Reduce -42.9% | 16 | $1K |
| Quarry LP | 0.00% | New | 26 | $941 |
| Allworth Financial LP | 0.00% | New | 23 | $833 |
| GAMMA Investing LLC | 0.00% | No change | 21 | $760 |
| US Bancorp \de | 0.00% | No change | 19 | $688 |
| Larson Financial Group LLC | 0.00% | New | 11 | $398 |
| Arax Advisory Partners | 0.00% | New | 10 | $362 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -76.3% | 9 | $326 |
| National Bank of Canada | 0.00% | New | 4 | $144 |
| Rothschild Investment LLC | 0.00% | New | 1 | $36 |
| Essential Partners LLC | 0.00% | New | 1 | $36 |
"% of holder's portfolio" is ETON's weight in each manager's 13F, not the share of Eton Pharmaceuticals Inc. the manager owns.