Edgewise TherapeuticsEWTX

13F holders, Q1 2025 (March 31)
192holders −8
31new positions
38sold out
6famous investors
$22.04avg. 13F price*

At the end of Q1 2025, 192 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, down 8 from Q4 2024. 31 opened new positions and 38 sold out. The largest holders were Orbimed Advisors LLC ($330.5M), Ra Capital Management, L.P. ($196.0M) and Perceptive Advisors LLC ($144.0M). 6 famous investors held it, including Andreas Halvorsen (0.0% of Viking Global Investors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Edgewise Therapeutics Inc.
CUSIP
28036F105
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 129Q1 2024Q2 2024: 140Q2 2024Q3 2024: 177Q3 2024Q4 2024: 200Q4 2024Q1 2025: 192Q1 2025Q2 2025: 178Q2 2025Q3 2025: 173Q3 2025Q4 2025: 199Q4 2025Q1 2026: 214Q1 2026Q2 2026: 226Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions31$43.7M
Exits38$80.0M

All 13F filers, Q4 2024 → Q1 2025: 13,235,233 shares bought and 6,669,066 shares sold, net +6,566,167 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 192 holders

Orbimed Advisors LLC 7.94% No change 15,021,721 $330.5M
Ra Capital Management, L.P. 3.27% No change 8,909,091 $196.0M
Perceptive Advisors LLC 5.11% Add +143.8% 6,547,328 $144.0M
BlackRock, Inc. 0.00% Add +0.1% 6,485,008 $142.7M
Baker Bros. Advisors LP 1.52% No change 6,155,940 $135.4M
Janus Henderson Group PLC 0.07% Add +6.0% 5,282,154 $122.9M
Novo Holdings A/S 8.95% Add +7.0% 5,350,000 $117.7M
Paradigm Biocapital Advisors LP 4.45% Reduce -2.2% 4,394,556 $96.7M
Vanguard Group Inc. 0.00% Reduce -3.9% 4,294,404 $94.5M
Cormorant Asset Management, LP 6.83% Add +20.4% 4,101,992 $90.2M
Braidwell LP 2.82% Add +5.4% 2,458,808 $54.1M
Deerfield Management Company, L.P. 1.03% No change 2,078,509 $45.7M
First Light Asset Management, LLC 4.65% Add +137.3% 1,852,290 $40.8M
State Street Corp. 0.00% Add +0.1% 1,717,724 $37.8M
Siren, L.L.C. 2.11% Add +131.0% 1,696,444 $37.3M
Geode Capital Management, LLC 0.00% Add +3.4% 1,655,664 $36.4M
Bellevue Group AG 0.70% No change 1,428,929 $31.4M
Deep Track Capital, LP 1.00% Add +97.1% 1,400,000 $30.8M
Driehaus Capital Management LLC 0.29% Reduce -7.9% 1,375,742 $30.3M
MPM Bioimpact LLC 4.18% Add +2.4% 1,105,444 $24.3M
Woodline Partners LP 0.16% Add +93.4% 1,096,809 $24.1M
New Leaf Venture Partners, L.L.C. 50.47% No change 1,030,161 $22.7M
Artisan Partners Limited Partnership 0.03% Reduce -14.4% 917,222 $20.2M
American Century Companies Inc. 0.01% Add +1.2% 779,766 $17.2M
Bank of America Corp. 0.00% Add +1321.9% 695,426 $15.3M
Integral Health Asset Management, LLC 1.65% Add +22.7% 675,000 $14.8M
Dimensional Fund Advisors LP 0.00% Reduce -8.6% 667,499 $14.7M
Millennium Management 0.01% Reduce -30.8% 615,118 $13.5M
Northern Trust Corp. 0.00% Reduce -0.8% 606,692 $13.3M
Foresite Capital Management VI LLC 7.05% No change 585,000 $12.9M
Eventide Asset Management, LLC 0.25% New 568,310 $12.5M
Charles Schwab Investment Management Inc. 0.00% Reduce -3.0% 521,261 $11.5M
Viking Global Investors 0.03% Reduce -60.0% 490,035 $10.8M
Parkman Healthcare Partners LLC 1.11% Add +11.6% 425,407 $9.4M
Morgan Stanley 0.00% Reduce -6.3% 408,997 $9.0M
Qube Research & Technologies Ltd 0.01% Add +7.6% 397,573 $8.7M
Opaleye Management Inc. 1.98% Reduce -17.7% 395,000 $8.7M
Adage Capital Partners Gp, L.L.C. 0.02% Add +62.5% 390,000 $8.6M
Deutsche Bank AG 0.00% Add +36.3% 376,060 $8.3M
Goldman Sachs Group Inc. 0.00% Add +5.7% 366,644 $8.1M
Readystate Asset Management LP 0.72% Add +1591.0% 361,233 $7.9M
Sofinnova Investments, Inc. 0.57% Reduce -15.0% 342,218 $7.5M
Aberdeen Group plc 0.01% Add +75.8% 313,025 $6.9M
Pictet Asset Management Holding SA 0.01% Add +0.4% 302,513 $6.7M
Tang Capital Management LLC 0.37% No change 300,000 $6.6M
T. Rowe Price Associates Inc. 0.00% Add +915.1% 294,881 $6.5M
Voya Investment Management LLC 0.01% Reduce -1.2% 280,735 $6.2M
Ikarian Capital, LLC 2.01% New 280,000 $6.2M
Schonfeld Strategic Advisors LLC 0.04% Add +3.9% 278,973 $6.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -2.3% 272,857 $6.0M
Polar Capital Holdings Plc 0.03% New 250,000 $5.5M
UBS Group AG 0.00% Add +164.9% 243,896 $5.4M
Candriam S.C.A. 0.03% Reduce -11.1% 225,796 $5.0M
Kennedy Capital Management LLC 0.12% Reduce -5.0% 224,700 $4.9M
Granahan Investment Management, LLC 0.24% Reduce -27.4% 217,667 $4.8M
Bank of New York Mellon Corp 0.00% Reduce -0.1% 210,735 $4.6M
Caption Management, LLC 0.21% New 204,500 $4.5M
Nuveen, LLC 0.00% — 202,580 $4.5M
Amundi 0.00% Reduce -9.7% 308,633 $4.2M
FMR LLC 0.00% Reduce -25.0% 186,023 $4.1M
DAFNA Capital Management LLC 1.16% Reduce -2.1% 183,140 $4.0M
Moody Aldrich Partners LLC 0.84% Reduce -3.1% 182,095 $4.0M
Stempoint Capital LP 1.27% Add +35.8% 180,255 $4.0M
Susquehanna International Group, LLP 0.01% Add +457.1% 176,666 $3.9M
D. E. Shaw & Co. 0.00% Reduce -79.5% 140,548 $3.1M
Jennison Associates LLC 0.00% New 128,746 $2.8M
Balyasny Asset Management L.P. 0.01% Add +417.5% 120,910 $2.7M
Wellington Management Group LLP 0.00% Reduce -44.2% 113,303 $2.5M
Rhumbline Advisers 0.00% Add +6.3% 108,837 $2.4M
Barclays PLC 0.00% Reduce -18.8% 108,562 $2.4M
EFG Asset Management (North America) Corp. 0.38% Add +152.5% 104,386 $2.3M
Ally Bridge Group (NY) LLC 2.04% Add +23.4% 102,650 $2.3M
Neuberger Berman Group LLC 0.00% New 102,181 $2.2M
Twinbeech Capital LP 0.04% New 100,826 $2.2M
Citadel Advisors 0.00% Reduce -79.3% 97,278 $2.1M
JPMorgan Chase & Co. 0.00% Reduce -26.6% 91,368 $2.0M
HighVista Strategies LLC 0.77% Add +10.2% 91,207 $2.0M
Quantum Private Wealth, LLC 0.76% Add +23.4% 90,724 $2.0M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Reduce -0.7% 89,425 $2.0M
Acuta Capital Partners, LLC 2.18% Reduce -2.5% 85,454 $1.9M
Boothbay Fund Management, LLC 0.07% New 85,214 $1.9M
Schroder Investment Management Group 0.00% Reduce -14.9% 79,151 $1.8M
Swiss National Bank 0.00% Add +12.2% 82,600 $1.8M
Alliancebernstein L.P. 0.00% No change 77,260 $1.7M
Bridger Management, LLC 0.82% No change 74,700 $1.6M
Citigroup Inc. 0.00% Reduce -5.3% 74,307 $1.6M
Soleus Capital Management, L.P. 0.12% Reduce -60.6% 72,300 $1.6M
New York State Common Retirement Fund 0.00% Add +0.1% 71,450 $1.6M
Exome Asset Management LLC 1.41% Reduce -12.3% 71,438 $1.6M
State of Wisconsin Investment Board 0.00% Add +15.6% 71,132 $1.6M
Alps Advisors Inc. 0.01% Reduce -11.2% 67,975 $1.5M
DekaBank Deutsche Girozentrale 0.00% No change 80,000 $1.4M
Manufacturers Life Insurance Company, The 0.00% Add +41.9% 56,988 $1.3M
Legal & General Group Plc 0.00% Add +0.1% 50,348 $1.1M
Prelude Capital Management, LLC 0.11% Add +50.8% 49,995 $1.1M
Invesco Ltd. 0.00% Add +10.8% 48,130 $1.1M
Norges Bank 0.00% No change 47,755 $1.1M
Tudor Investment Corporation 0.01% Add +6.8% 46,804 $1.0M
Franklin Resources Inc. 0.00% Add +46.5% 46,287 $1.0M
Intech Investment Management LLC 0.01% Add +32.6% 46,208 $1.0M
Squarepoint Ops LLC 0.00% Add +73.6% 45,756 $1.0M
MetLife Investment Management, LLC 0.01% Reduce -1.6% 43,883 $965K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +6.0% 43,776 $963K
Sei Investments Co. 0.00% Reduce -17.7% 42,962 $945K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% New 40,014 $880K
Skandinaviska Enskilda Banken AB (publ) 0.00% New 37,591 $827K
Engineers Gate Manager LP 0.01% New 36,358 $800K
Corebridge Financial, Inc. 0.00% Reduce -0.1% 36,049 $793K
California State Teachers Retirement System 0.00% Reduce -4.3% 36,028 $793K
Wells Fargo & Company 0.00% Add +3.7% 35,158 $773K
Two Sigma Investments, LP 0.00% Reduce -73.4% 34,999 $770K
Verition Fund Management LLC 0.00% Reduce -25.2% 34,719 $764K
TD Asset Management Inc 0.00% New 33,200 $730K
Fred Alger Management, LLC 0.00% New 27,635 $608K
Handelsbanken Fonder AB 0.00% No change 21,800 $480K
Glenmede Trust Co. NA 0.00% Reduce -0.5% 21,809 $480K
ProShare Advisors LLC 0.00% Reduce -18.9% 20,203 $444K
ADAR1 Capital Management, LLC 0.09% New 20,000 $440K
China Universal Asset Management Co., Ltd. 0.04% Reduce -5.4% 18,993 $418K
Graham Capital Management, L.P. 0.02% Reduce -7.4% 17,047 $375K
State Board of Administration of Florida Retirement System 0.00% No change 16,870 $371K
Cibc World Markets Corp. 0.00% New 16,328 $359K
Walleye Capital LLC 0.00% Reduce -91.9% 16,178 $356K
Profund Advisors LLC 0.01% Add +5.0% 15,687 $345K
Police & Firemen's Retirement System of New Jersey 0.00% No change 15,453 $340K
Envestnet Asset Management Inc. 0.00% Add +4.9% 15,399 $339K
Jane Street Group, LLC 0.00% Reduce -51.7% 14,758 $325K
Ameriprise Financial Inc. 0.00% Reduce -41.7% 13,167 $290K
Creative Planning 0.00% New 13,073 $288K
SG Americas Securities, LLC 0.00% New 12,883 $283K
Group One Trading LLC 0.01% Add +2553.6% 12,631 $278K
Rafferty Asset Management, LLC 0.00% Add +2.6% 12,217 $269K
Arizona State Retirement System 0.00% Add +12.3% 12,201 $268K
Orion Porfolio Solutions, LLC 0.00% Reduce -2.5% 11,633 $256K
Orion Portfolio Solutions, LLC 0.00% Reduce -2.5% 11,633 $256K
Teacher Retirement System of Texas 0.00% Add +2.5% 11,421 $251K
Contravisory Investment Management, Inc. 0.05% New 10,209 $225K
Sfmg, LLC 0.02% No change 10,000 $220K
HSBC Holdings PLC 0.00% Reduce -8.2% 9,874 $219K
SummitTX Capital, L.P. 0.01% — 9,664 $213K
AQR Capital Management 0.00% Add +0.6% 9,419 $207K
AlphaQuest LLC 0.02% Add +324.8% 9,358 $206K
Tidal Investments LLC 0.00% New 9,220 $203K
Tower Research Capital LLC (TRC) 0.01% Add +116.5% 7,960 $175K
Ameritas Investment Partners, Inc. 0.01% No change 7,594 $167K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -10.4% 7,073 $156K
KLP Kapitalforvaltning As 0.00% No change 6,800 $150K
Virtus Investment Advisers, LLC 0.04% New 5,829 $128K
Royal Bank of Canada 0.00% Add +72.3% 5,729 $126K
BNP Paribas Financial Markets 0.00% Reduce -83.4% 5,504 $121K
STRS Ohio 0.00% Reduce -53.7% 3,800 $84K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +0.4% 3,168 $74K
US Bancorp \de 0.00% Reduce -2.9% 3,213 $71K
Caitong International Asset Management Co., Ltd 0.05% Add +55.6% 3,194 $70K
Allostery Investments LP 0.10% New 3,000 $66K
Public Employees Retirement Association of Colorado 0.00% No change 2,849 $63K
Amalgamated Bank 0.00% Add +0.4% 2,521 $55K
GF Fund Management Co. LTD. 0.00% Add +21.9% 2,424 $53K
Walleye Trading LLC 0.00% New 1,456 $32K
GAMMA Investing LLC 0.00% Add +6.5% 1,407 $31K
Quarry LP 0.01% Reduce -40.0% 1,200 $26K
BI Asset Management Fondsmaeglerselskab A/S 0.00% Reduce -86.9% 1,163 $26K
Nisa Investment Advisors, LLC 0.00% Add +0.7% 1,056 $23K
Crowley Wealth Management, Inc. 0.01% New 560 $12K
Signaturefd, LLC 0.00% Add +5.6% 492 $11K
Daiwa Securities Group Inc. 0.00% No change 344 $8K
MassMutual Private Wealth & Trust, FSB 0.00% New 356 $8K
Lindbrook Capital, LLC 0.00% Reduce -12.3% 285 $6K
Coldstream Capital Management Inc. 0.00% New 282 $6K
SBI Securities Co., Ltd. 0.00% No change 243 $5K
Summit Securities Group LLC 0.00% New 198 $4K
HighMark Wealth Management LLC 0.00% No change 165 $4K
Fortitude Family Office, LLC 0.00% No change 160 $4K
Parallel Advisors, LLC 0.00% Reduce -2.2% 133 $3K
Comerica Bank 0.00% Add +12.0% 121 $3K
Osaic Holdings, Inc. 0.00% Reduce -88.6% 121 $3K
Rothschild Investment LLC 0.00% Add +33.3% 120 $3K
Bfsg, LLC 0.00% Reduce -66.7% 100 $2K
Federated Hermes, Inc. 0.00% Reduce -25.2% 80 $2K
Sterling Capital Management LLC 0.00% No change 75 $2K
TD Private Client Wealth LLC 0.00% New 60 $1K
Cwm, LLC 0.00% Add +134.6% 61 $1K
Parkside Financial Bank & Trust 0.00% New 40 $880
Versant Capital Management, Inc 0.00% No change 40 $880
Jones Financial Companies LLLP 0.00% New 32 $745
Principal Securities, Inc. 0.00% No change 27 $721
Creative Financial Designs Inc. 0.00% New 31 $682
Stephens Consulting, LLC 0.00% New 30 $660
Smartleaf Asset Management LLC 0.00% No change 21 $488
Russell Investments Group, Ltd. 0.00% Reduce -99.9% 19 $418
Farther Finance Advisors, LLC 0.00% No change 8 $161
Covestor Ltd 0.00% No change 5 $0

"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.