Edgewise TherapeuticsEWTX
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 192 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, down 8 from Q4 2024. 31 opened new positions and 38 sold out. The largest holders were Orbimed Advisors LLC ($330.5M), Ra Capital Management, L.P. ($196.0M) and Perceptive Advisors LLC ($144.0M). 6 famous investors held it, including Andreas Halvorsen (0.0% of Viking Global Investors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Edgewise Therapeutics Inc.
- CUSIP
- 28036F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $43.7M |
| Exits | 38 | $80.0M |
All 13F filers, Q4 2024 → Q1 2025: 13,235,233 shares bought and 6,669,066 shares sold, net +6,566,167 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 192 holders
| Orbimed Advisors LLC | 7.94% | No change | 15,021,721 | $330.5M |
| Ra Capital Management, L.P. | 3.27% | No change | 8,909,091 | $196.0M |
| Perceptive Advisors LLC | 5.11% | Add +143.8% | 6,547,328 | $144.0M |
| BlackRock, Inc. | 0.00% | Add +0.1% | 6,485,008 | $142.7M |
| Baker Bros. Advisors LP | 1.52% | No change | 6,155,940 | $135.4M |
| Janus Henderson Group PLC | 0.07% | Add +6.0% | 5,282,154 | $122.9M |
| Novo Holdings A/S | 8.95% | Add +7.0% | 5,350,000 | $117.7M |
| Paradigm Biocapital Advisors LP | 4.45% | Reduce -2.2% | 4,394,556 | $96.7M |
| Vanguard Group Inc. | 0.00% | Reduce -3.9% | 4,294,404 | $94.5M |
| Cormorant Asset Management, LP | 6.83% | Add +20.4% | 4,101,992 | $90.2M |
| Braidwell LP | 2.82% | Add +5.4% | 2,458,808 | $54.1M |
| Deerfield Management Company, L.P. | 1.03% | No change | 2,078,509 | $45.7M |
| First Light Asset Management, LLC | 4.65% | Add +137.3% | 1,852,290 | $40.8M |
| State Street Corp. | 0.00% | Add +0.1% | 1,717,724 | $37.8M |
| Siren, L.L.C. | 2.11% | Add +131.0% | 1,696,444 | $37.3M |
| Geode Capital Management, LLC | 0.00% | Add +3.4% | 1,655,664 | $36.4M |
| Bellevue Group AG | 0.70% | No change | 1,428,929 | $31.4M |
| Deep Track Capital, LP | 1.00% | Add +97.1% | 1,400,000 | $30.8M |
| Driehaus Capital Management LLC | 0.29% | Reduce -7.9% | 1,375,742 | $30.3M |
| MPM Bioimpact LLC | 4.18% | Add +2.4% | 1,105,444 | $24.3M |
| Woodline Partners LP | 0.16% | Add +93.4% | 1,096,809 | $24.1M |
| New Leaf Venture Partners, L.L.C. | 50.47% | No change | 1,030,161 | $22.7M |
| Artisan Partners Limited Partnership | 0.03% | Reduce -14.4% | 917,222 | $20.2M |
| American Century Companies Inc. | 0.01% | Add +1.2% | 779,766 | $17.2M |
| Bank of America Corp. | 0.00% | Add +1321.9% | 695,426 | $15.3M |
| Integral Health Asset Management, LLC | 1.65% | Add +22.7% | 675,000 | $14.8M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -8.6% | 667,499 | $14.7M |
| Millennium Management | 0.01% | Reduce -30.8% | 615,118 | $13.5M |
| Northern Trust Corp. | 0.00% | Reduce -0.8% | 606,692 | $13.3M |
| Foresite Capital Management VI LLC | 7.05% | No change | 585,000 | $12.9M |
| Eventide Asset Management, LLC | 0.25% | New | 568,310 | $12.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.0% | 521,261 | $11.5M |
| Viking Global Investors | 0.03% | Reduce -60.0% | 490,035 | $10.8M |
| Parkman Healthcare Partners LLC | 1.11% | Add +11.6% | 425,407 | $9.4M |
| Morgan Stanley | 0.00% | Reduce -6.3% | 408,997 | $9.0M |
| Qube Research & Technologies Ltd | 0.01% | Add +7.6% | 397,573 | $8.7M |
| Opaleye Management Inc. | 1.98% | Reduce -17.7% | 395,000 | $8.7M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Add +62.5% | 390,000 | $8.6M |
| Deutsche Bank AG | 0.00% | Add +36.3% | 376,060 | $8.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +5.7% | 366,644 | $8.1M |
| Readystate Asset Management LP | 0.72% | Add +1591.0% | 361,233 | $7.9M |
| Sofinnova Investments, Inc. | 0.57% | Reduce -15.0% | 342,218 | $7.5M |
| Aberdeen Group plc | 0.01% | Add +75.8% | 313,025 | $6.9M |
| Pictet Asset Management Holding SA | 0.01% | Add +0.4% | 302,513 | $6.7M |
| Tang Capital Management LLC | 0.37% | No change | 300,000 | $6.6M |
| T. Rowe Price Associates Inc. | 0.00% | Add +915.1% | 294,881 | $6.5M |
| Voya Investment Management LLC | 0.01% | Reduce -1.2% | 280,735 | $6.2M |
| Ikarian Capital, LLC | 2.01% | New | 280,000 | $6.2M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +3.9% | 278,973 | $6.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -2.3% | 272,857 | $6.0M |
| Polar Capital Holdings Plc | 0.03% | New | 250,000 | $5.5M |
| UBS Group AG | 0.00% | Add +164.9% | 243,896 | $5.4M |
| Candriam S.C.A. | 0.03% | Reduce -11.1% | 225,796 | $5.0M |
| Kennedy Capital Management LLC | 0.12% | Reduce -5.0% | 224,700 | $4.9M |
| Granahan Investment Management, LLC | 0.24% | Reduce -27.4% | 217,667 | $4.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.1% | 210,735 | $4.6M |
| Caption Management, LLC | 0.21% | New | 204,500 | $4.5M |
| Nuveen, LLC | 0.00% | — | 202,580 | $4.5M |
| Amundi | 0.00% | Reduce -9.7% | 308,633 | $4.2M |
| FMR LLC | 0.00% | Reduce -25.0% | 186,023 | $4.1M |
| DAFNA Capital Management LLC | 1.16% | Reduce -2.1% | 183,140 | $4.0M |
| Moody Aldrich Partners LLC | 0.84% | Reduce -3.1% | 182,095 | $4.0M |
| Stempoint Capital LP | 1.27% | Add +35.8% | 180,255 | $4.0M |
| Susquehanna International Group, LLP | 0.01% | Add +457.1% | 176,666 | $3.9M |
| D. E. Shaw & Co. | 0.00% | Reduce -79.5% | 140,548 | $3.1M |
| Jennison Associates LLC | 0.00% | New | 128,746 | $2.8M |
| Balyasny Asset Management L.P. | 0.01% | Add +417.5% | 120,910 | $2.7M |
| Wellington Management Group LLP | 0.00% | Reduce -44.2% | 113,303 | $2.5M |
| Rhumbline Advisers | 0.00% | Add +6.3% | 108,837 | $2.4M |
| Barclays PLC | 0.00% | Reduce -18.8% | 108,562 | $2.4M |
| EFG Asset Management (North America) Corp. | 0.38% | Add +152.5% | 104,386 | $2.3M |
| Ally Bridge Group (NY) LLC | 2.04% | Add +23.4% | 102,650 | $2.3M |
| Neuberger Berman Group LLC | 0.00% | New | 102,181 | $2.2M |
| Twinbeech Capital LP | 0.04% | New | 100,826 | $2.2M |
| Citadel Advisors | 0.00% | Reduce -79.3% | 97,278 | $2.1M |
| JPMorgan Chase & Co. | 0.00% | Reduce -26.6% | 91,368 | $2.0M |
| HighVista Strategies LLC | 0.77% | Add +10.2% | 91,207 | $2.0M |
| Quantum Private Wealth, LLC | 0.76% | Add +23.4% | 90,724 | $2.0M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -0.7% | 89,425 | $2.0M |
| Acuta Capital Partners, LLC | 2.18% | Reduce -2.5% | 85,454 | $1.9M |
| Boothbay Fund Management, LLC | 0.07% | New | 85,214 | $1.9M |
| Schroder Investment Management Group | 0.00% | Reduce -14.9% | 79,151 | $1.8M |
| Swiss National Bank | 0.00% | Add +12.2% | 82,600 | $1.8M |
| Alliancebernstein L.P. | 0.00% | No change | 77,260 | $1.7M |
| Bridger Management, LLC | 0.82% | No change | 74,700 | $1.6M |
| Citigroup Inc. | 0.00% | Reduce -5.3% | 74,307 | $1.6M |
| Soleus Capital Management, L.P. | 0.12% | Reduce -60.6% | 72,300 | $1.6M |
| New York State Common Retirement Fund | 0.00% | Add +0.1% | 71,450 | $1.6M |
| Exome Asset Management LLC | 1.41% | Reduce -12.3% | 71,438 | $1.6M |
| State of Wisconsin Investment Board | 0.00% | Add +15.6% | 71,132 | $1.6M |
| Alps Advisors Inc. | 0.01% | Reduce -11.2% | 67,975 | $1.5M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 80,000 | $1.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +41.9% | 56,988 | $1.3M |
| Legal & General Group Plc | 0.00% | Add +0.1% | 50,348 | $1.1M |
| Prelude Capital Management, LLC | 0.11% | Add +50.8% | 49,995 | $1.1M |
| Invesco Ltd. | 0.00% | Add +10.8% | 48,130 | $1.1M |
| Norges Bank | 0.00% | No change | 47,755 | $1.1M |
| Tudor Investment Corporation | 0.01% | Add +6.8% | 46,804 | $1.0M |
| Franklin Resources Inc. | 0.00% | Add +46.5% | 46,287 | $1.0M |
| Intech Investment Management LLC | 0.01% | Add +32.6% | 46,208 | $1.0M |
| Squarepoint Ops LLC | 0.00% | Add +73.6% | 45,756 | $1.0M |
| MetLife Investment Management, LLC | 0.01% | Reduce -1.6% | 43,883 | $965K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +6.0% | 43,776 | $963K |
| Sei Investments Co. | 0.00% | Reduce -17.7% | 42,962 | $945K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | New | 40,014 | $880K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | New | 37,591 | $827K |
| Engineers Gate Manager LP | 0.01% | New | 36,358 | $800K |
| Corebridge Financial, Inc. | 0.00% | Reduce -0.1% | 36,049 | $793K |
| California State Teachers Retirement System | 0.00% | Reduce -4.3% | 36,028 | $793K |
| Wells Fargo & Company | 0.00% | Add +3.7% | 35,158 | $773K |
| Two Sigma Investments, LP | 0.00% | Reduce -73.4% | 34,999 | $770K |
| Verition Fund Management LLC | 0.00% | Reduce -25.2% | 34,719 | $764K |
| TD Asset Management Inc | 0.00% | New | 33,200 | $730K |
| Fred Alger Management, LLC | 0.00% | New | 27,635 | $608K |
| Handelsbanken Fonder AB | 0.00% | No change | 21,800 | $480K |
| Glenmede Trust Co. NA | 0.00% | Reduce -0.5% | 21,809 | $480K |
| ProShare Advisors LLC | 0.00% | Reduce -18.9% | 20,203 | $444K |
| ADAR1 Capital Management, LLC | 0.09% | New | 20,000 | $440K |
| China Universal Asset Management Co., Ltd. | 0.04% | Reduce -5.4% | 18,993 | $418K |
| Graham Capital Management, L.P. | 0.02% | Reduce -7.4% | 17,047 | $375K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,870 | $371K |
| Cibc World Markets Corp. | 0.00% | New | 16,328 | $359K |
| Walleye Capital LLC | 0.00% | Reduce -91.9% | 16,178 | $356K |
| Profund Advisors LLC | 0.01% | Add +5.0% | 15,687 | $345K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 15,453 | $340K |
| Envestnet Asset Management Inc. | 0.00% | Add +4.9% | 15,399 | $339K |
| Jane Street Group, LLC | 0.00% | Reduce -51.7% | 14,758 | $325K |
| Ameriprise Financial Inc. | 0.00% | Reduce -41.7% | 13,167 | $290K |
| Creative Planning | 0.00% | New | 13,073 | $288K |
| SG Americas Securities, LLC | 0.00% | New | 12,883 | $283K |
| Group One Trading LLC | 0.01% | Add +2553.6% | 12,631 | $278K |
| Rafferty Asset Management, LLC | 0.00% | Add +2.6% | 12,217 | $269K |
| Arizona State Retirement System | 0.00% | Add +12.3% | 12,201 | $268K |
| Orion Porfolio Solutions, LLC | 0.00% | Reduce -2.5% | 11,633 | $256K |
| Orion Portfolio Solutions, LLC | 0.00% | Reduce -2.5% | 11,633 | $256K |
| Teacher Retirement System of Texas | 0.00% | Add +2.5% | 11,421 | $251K |
| Contravisory Investment Management, Inc. | 0.05% | New | 10,209 | $225K |
| Sfmg, LLC | 0.02% | No change | 10,000 | $220K |
| HSBC Holdings PLC | 0.00% | Reduce -8.2% | 9,874 | $219K |
| SummitTX Capital, L.P. | 0.01% | — | 9,664 | $213K |
| AQR Capital Management | 0.00% | Add +0.6% | 9,419 | $207K |
| AlphaQuest LLC | 0.02% | Add +324.8% | 9,358 | $206K |
| Tidal Investments LLC | 0.00% | New | 9,220 | $203K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +116.5% | 7,960 | $175K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 7,594 | $167K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -10.4% | 7,073 | $156K |
| KLP Kapitalforvaltning As | 0.00% | No change | 6,800 | $150K |
| Virtus Investment Advisers, LLC | 0.04% | New | 5,829 | $128K |
| Royal Bank of Canada | 0.00% | Add +72.3% | 5,729 | $126K |
| BNP Paribas Financial Markets | 0.00% | Reduce -83.4% | 5,504 | $121K |
| STRS Ohio | 0.00% | Reduce -53.7% | 3,800 | $84K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 3,168 | $74K |
| US Bancorp \de | 0.00% | Reduce -2.9% | 3,213 | $71K |
| Caitong International Asset Management Co., Ltd | 0.05% | Add +55.6% | 3,194 | $70K |
| Allostery Investments LP | 0.10% | New | 3,000 | $66K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 2,849 | $63K |
| Amalgamated Bank | 0.00% | Add +0.4% | 2,521 | $55K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 2,424 | $53K |
| Walleye Trading LLC | 0.00% | New | 1,456 | $32K |
| GAMMA Investing LLC | 0.00% | Add +6.5% | 1,407 | $31K |
| Quarry LP | 0.01% | Reduce -40.0% | 1,200 | $26K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | Reduce -86.9% | 1,163 | $26K |
| Nisa Investment Advisors, LLC | 0.00% | Add +0.7% | 1,056 | $23K |
| Crowley Wealth Management, Inc. | 0.01% | New | 560 | $12K |
| Signaturefd, LLC | 0.00% | Add +5.6% | 492 | $11K |
| Daiwa Securities Group Inc. | 0.00% | No change | 344 | $8K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 356 | $8K |
| Lindbrook Capital, LLC | 0.00% | Reduce -12.3% | 285 | $6K |
| Coldstream Capital Management Inc. | 0.00% | New | 282 | $6K |
| SBI Securities Co., Ltd. | 0.00% | No change | 243 | $5K |
| Summit Securities Group LLC | 0.00% | New | 198 | $4K |
| HighMark Wealth Management LLC | 0.00% | No change | 165 | $4K |
| Fortitude Family Office, LLC | 0.00% | No change | 160 | $4K |
| Parallel Advisors, LLC | 0.00% | Reduce -2.2% | 133 | $3K |
| Comerica Bank | 0.00% | Add +12.0% | 121 | $3K |
| Osaic Holdings, Inc. | 0.00% | Reduce -88.6% | 121 | $3K |
| Rothschild Investment LLC | 0.00% | Add +33.3% | 120 | $3K |
| Bfsg, LLC | 0.00% | Reduce -66.7% | 100 | $2K |
| Federated Hermes, Inc. | 0.00% | Reduce -25.2% | 80 | $2K |
| Sterling Capital Management LLC | 0.00% | No change | 75 | $2K |
| TD Private Client Wealth LLC | 0.00% | New | 60 | $1K |
| Cwm, LLC | 0.00% | Add +134.6% | 61 | $1K |
| Parkside Financial Bank & Trust | 0.00% | New | 40 | $880 |
| Versant Capital Management, Inc | 0.00% | No change | 40 | $880 |
| Jones Financial Companies LLLP | 0.00% | New | 32 | $745 |
| Principal Securities, Inc. | 0.00% | No change | 27 | $721 |
| Creative Financial Designs Inc. | 0.00% | New | 31 | $682 |
| Stephens Consulting, LLC | 0.00% | New | 30 | $660 |
| Smartleaf Asset Management LLC | 0.00% | No change | 21 | $488 |
| Russell Investments Group, Ltd. | 0.00% | Reduce -99.9% | 19 | $418 |
| Farther Finance Advisors, LLC | 0.00% | No change | 8 | $161 |
| Covestor Ltd | 0.00% | No change | 5 | $0 |
"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.