Heron TherapeuticsHRTX
13F holders, Q4 2025 (December 31)170holders −2
21new positions
25sold out
5famous investors
$1.32avg. 13F price*
At the end of Q4 2025, 170 institutions reported holding Heron Therapeutics Inc. (HRTX) in their 13F filings, down 2 from Q3 2025. 21 opened new positions and 25 sold out. The largest holders were Rubric Capital Management LP ($39.1M), Clearline Capital LP ($15.9M) and Adage Capital Partners Gp, L.L.C. ($14.5M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Heron Therapeutics Inc.
- CUSIP
- 427746102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $1.5M |
| Exits | 25 | $9.3M |
All 13F filers, Q3 2025 → Q4 2025: 23,443,191 shares bought and 19,693,537 shares sold, net +3,749,654 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 170 holders
| Rubric Capital Management LP | 0.47% | Add +3.3% | 30,046,828 | $39.1M |
| Clearline Capital LP | 1.20% | Add +26.0% | 12,235,239 | $15.9M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Add +9.2% | 11,185,325 | $14.5M |
| BlackRock, Inc. | 0.00% | Add +2.3% | 10,218,236 | $13.3M |
| Vanguard Group Inc. | 0.00% | Add +16.1% | 9,820,384 | $12.8M |
| Velan Capital Investment Management LP | 6.62% | No change | 8,753,290 | $11.4M |
| Millennium Management | 0.01% | Add +2785.2% | 7,169,908 | $9.3M |
| Palisade Capital Management, LP | 0.27% | Reduce -13.7% | 6,326,113 | $8.2M |
| Tang Capital Management LLC | 0.40% | Add +81.2% | 6,250,000 | $8.1M |
| Tejara Capital Ltd | 2.77% | Add +11.8% | 5,131,426 | $6.7M |
| Geode Capital Management, LLC | 0.00% | Add +12.0% | 4,081,222 | $5.3M |
| State Street Corp. | 0.00% | Add +3.5% | 3,778,043 | $4.9M |
| JW Asset Management, LLC | 1.55% | Add +11.5% | 3,671,073 | $4.8M |
| Congress Park Capital LLC | 1.19% | Add +6.1% | 3,067,475 | $4.0M |
| D. E. Shaw & Co. | 0.00% | Reduce -2.7% | 3,004,640 | $3.9M |
| Focus Partners Wealth | 0.00% | Add +697.6% | 148,470 | $3.6M |
| New York State Common Retirement Fund | 0.00% | No change | 2,576,716 | $3.3M |
| Citadel Advisors | 0.00% | Reduce -22.6% | 2,095,045 | $2.7M |
| UBS Group AG | 0.00% | Reduce -28.7% | 2,091,669 | $2.7M |
| Renaissance Technologies | 0.00% | Reduce -32.9% | 1,915,900 | $2.5M |
| Pale Fire Capital SE | 0.25% | Add +211.9% | 1,469,655 | $1.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +10.8% | 1,415,336 | $1.8M |
| Jane Street Group, LLC | 0.00% | Add +520.9% | 1,367,891 | $1.8M |
| Stonepine Capital Management, LLC | 1.27% | Add +45.6% | 1,237,802 | $1.6M |
| Monaco Asset Management SAM | 0.49% | Add +23.0% | 1,233,022 | $1.6M |
| Northern Trust Corp. | 0.00% | Reduce -5.7% | 1,091,411 | $1.4M |
| Two Sigma Investments, LP | 0.00% | Add +44.4% | 999,509 | $1.3M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -25.3% | 989,796 | $1.3M |
| Morgan Stanley | 0.00% | Reduce -61.0% | 963,851 | $1.3M |
| CM Management, LLC | 0.82% | No change | 750,000 | $975K |
| Orchard Capital Management, LLC | 0.77% | Add +0.5% | 680,432 | $885K |
| Squarepoint Ops LLC | 0.00% | Add +215.2% | 677,947 | $881K |
| Richmond Brothers, Inc. | 0.47% | No change | 572,118 | $744K |
| Two Sigma Advisers, LP | 0.00% | Add +185.4% | 519,571 | $675K |
| Nexpoint Asset Management, L.P. | 0.04% | No change | 475,750 | $618K |
| Panagora Asset Management Inc. | 0.00% | New | 440,252 | $572K |
| Bank of New York Mellon Corp | 0.00% | Add +1.5% | 418,477 | $544K |
| AQR Capital Management | 0.00% | Reduce -80.6% | 376,300 | $489K |
| Nuveen, LLC | 0.00% | No change | 347,065 | $451K |
| Susquehanna International Group, LLP | 0.00% | Add +3.4% | 340,246 | $442K |
| Invesco Ltd. | 0.00% | Add +33.0% | 307,861 | $400K |
| Barclays PLC | 0.00% | Add +8.5% | 303,209 | $394K |
| Apeiron RIA LLC | 0.07% | Add +16.6% | 259,968 | $359K |
| Palumbo Wealth Management LLC | 0.08% | Add +19.8% | 259,413 | $337K |
| Cyndeo Wealth Partners, LLC | 0.02% | No change | 248,087 | $323K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -65.4% | 242,000 | $315K |
| XTX Topco Ltd | 0.01% | Add +687.6% | 240,197 | $312K |
| Quadrature Capital Ltd | 0.00% | New | 227,784 | $296K |
| Los Angeles Capital Management LLC | 0.00% | Add +0.9% | 248,567 | $283K |
| Rhumbline Advisers | 0.00% | Reduce -9.5% | 203,319 | $264K |
| Alliancebernstein L.P. | 0.00% | No change | 198,550 | $258K |
| Wells Fargo & Company | 0.00% | Add +45.9% | 179,620 | $234K |
| Quinn Opportunity Partners LLC | 0.01% | No change | 175,344 | $228K |
| Group One Trading LLC | 0.01% | New | 145,167 | $189K |
| Capital Planning Advisors, LLC | 0.03% | No change | 144,095 | $187K |
| Gsa Capital Partners LLP | 0.02% | Add +34.8% | 135,089 | $176K |
| Bank of America Corp. | 0.00% | Reduce -81.6% | 134,445 | $175K |
| Raymond James Financial Inc. | 0.00% | Add +7.6% | 120,199 | $156K |
| Simplex Trading, LLC | 0.00% | Add +326.5% | 114,604 | $149K |
| Biltmore Family Office, LLC | 0.02% | No change | 100,000 | $130K |
| Integrated Wealth Concepts LLC | 0.00% | Reduce -2.5% | 95,174 | $124K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +12.3% | 94,009 | $122K |
| Deutsche Bank AG | 0.00% | Add +9.3% | 93,081 | $121K |
| MetLife Investment Management, LLC | 0.00% | Reduce -5.0% | 87,754 | $114K |
| Searle & Co. | 0.03% | No change | 86,250 | $112K |
| FMR LLC | 0.00% | Add +77.7% | 84,197 | $109K |
| Glenmede Trust Co. NA | 0.00% | — | 82,189 | $107K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 76,638 | $100K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -0.7% | 71,369 | $93K |
| Redwood Family Wealth LLC | 0.08% | — | 64,500 | $84K |
| JPMorgan Chase & Co. | 0.00% | Reduce -95.2% | 62,396 | $81K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -1.0% | 59,426 | $77K |
| Intech Investment Management LLC | 0.00% | Reduce -19.1% | 59,369 | $77K |
| State of Wyoming | 0.01% | New | 58,624 | $76K |
| Cornerstone Select Advisors, LLC | 0.05% | Reduce -1.7% | 58,070 | $75K |
| LPL Financial LLC | 0.00% | Add +10.4% | 55,889 | $73K |
| Headlands Technologies LLC | 0.01% | Add +158.3% | 51,287 | $67K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -6.4% | 48,659 | $63K |
| Atom Investors LP | 0.01% | New | 48,178 | $63K |
| Abel Hall, LLC | 0.01% | New | 46,176 | $60K |
| Captrust Financial Advisors | 0.00% | Reduce -15.1% | 41,590 | $54K |
| Prospera Financial Services Inc | 0.00% | Reduce -21.5% | 40,565 | $53K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 38,352 | $50K |
| Caitong International Asset Management Co., Ltd | 0.01% | Add +335.2% | 35,106 | $46K |
| Brevan Howard Capital Management LP | 0.00% | New | 35,036 | $46K |
| HSBC Holdings PLC | 0.00% | Reduce -0.2% | 33,381 | $44K |
| BNP Paribas Financial Markets | 0.00% | Reduce -91.3% | 32,870 | $43K |
| Concurrent Investment Advisors, LLC | 0.00% | New | 31,923 | $42K |
| King Wealth Management Group | 0.00% | Add +3.4% | 30,799 | $40K |
| Anfield Capital Management, LLC | 0.01% | No change | 30,000 | $39K |
| CoreCap Advisors, LLC | 0.00% | No change | 28,409 | $37K |
| ProShare Advisors LLC | 0.00% | Add +7.3% | 28,075 | $36K |
| Jones Financial Companies LLLP | 0.00% | Add +16.1% | 27,955 | $36K |
| Voya Investment Management LLC | 0.00% | No change | 27,653 | $36K |
| Valeo Financial Advisors, LLC | 0.00% | No change | 26,697 | $35K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -0.8% | 26,422 | $34K |
| ACT Advisors, LLC. | 0.01% | Add +0.9% | 25,808 | $34K |
| Parkway Wealth Management Group, LLC | 0.00% | — | 25,000 | $33K |
| SG Americas Securities, LLC | 0.00% | Add +39.1% | 24,377 | $32K |
| Victory Capital Management Inc. | 0.00% | Add +0.1% | 20,914 | $27K |
| Argent Advisors, Inc. | 0.01% | No change | 20,000 | $26K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +68.4% | 19,393 | $25K |
| Mariner, LLC | 0.00% | Reduce -47.1% | 18,999 | $25K |
| Advisory Services Network, LLC | 0.00% | Add +2383.4% | 18,874 | $25K |
| StoneX Group Inc. | 0.00% | New | 18,809 | $24K |
| Nicolet Advisory Services, LLC | 0.00% | No change | 16,000 | $24K |
| Capital Investment Counsel, Inc | 0.00% | New | 18,325 | $24K |
| Cerity Partners LLC | 0.00% | Reduce -67.0% | 17,063 | $22K |
| Ieq Capital, LLC | 0.00% | Reduce -78.5% | 16,988 | $22K |
| HighTower Advisors, LLC | 0.00% | Reduce -19.2% | 16,796 | $22K |
| J.W. Cole Advisors, Inc. | 0.00% | No change | 16,000 | $21K |
| Pekin Hardy Strauss, Inc. | 0.00% | New | 15,992 | $21K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 15,618 | $20K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +0.5% | 14,896 | $19K |
| Legal & General Group Plc | 0.00% | No change | 14,237 | $19K |
| Cetera Investment Advisers | 0.00% | No change | 13,997 | $18K |
| Cresset Asset Management, LLC | 0.00% | New | 13,390 | $17K |
| Mercer Global Advisors Inc. | 0.00% | Reduce -49.9% | 13,380 | $17K |
| Aigen Investment Management, LP | 0.00% | New | 12,717 | $17K |
| Sei Investments Co. | 0.00% | No change | 12,685 | $16K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -26.4% | 12,671 | $16K |
| Royal Bank of Canada | 0.00% | Add +97.8% | 11,793 | $16K |
| Two Sigma Securities, LLC | 0.00% | New | 12,136 | $16K |
| B. Riley Wealth Advisors, Inc. | 0.00% | No change | 12,117 | $16K |
| Xponance LLC | 0.00% | No change | 11,893 | $15K |
| DLK Investment Management, LLC | 0.01% | Reduce -47.3% | 11,690 | $15K |
| Ingalls & Snyder LLC | 0.00% | No change | 11,415 | $15K |
| Cwm, LLC | 0.00% | Reduce -76.4% | 10,628 | $14K |
| Venturi Wealth Management, LLC | 0.00% | No change | 10,500 | $14K |
| Red Door Wealth Management, LLC | 0.00% | New | 10,400 | $14K |
| HB Wealth Management, LLC | 0.00% | Reduce -10.2% | 10,301 | $13K |
| Cibc World Markets Corp. | 0.00% | — | 10,165 | $13K |
| XML Financial, LLC | 0.00% | No change | 10,000 | $13K |
| Lido Advisors, LLC | 0.00% | No change | 10,072 | $13K |
| HBK Sorce Advisory LLC | 0.00% | No change | 10,000 | $13K |
| California State Teachers Retirement System | 0.00% | Add +11.1% | 9,458 | $12K |
| Allworth Financial LP | 0.00% | Add +500.3% | 9,329 | $12K |
| Sterling Capital Management LLC | 0.00% | Reduce -15.3% | 7,976 | $10K |
| JTC Employer Solutions Trustee Ltd | 0.00% | No change | 6,500 | $8K |
| Osaic Holdings, Inc. | 0.00% | Add +27.7% | 4,968 | $6K |
| Comerica Bank | 0.00% | Reduce -1.4% | 4,951 | $6K |
| Amalgamated Bank | 0.00% | Add +19.3% | 4,827 | $6K |
| Global Retirement Partners, LLC | 0.00% | No change | 4,018 | $5K |
| Citigroup Inc. | 0.00% | Reduce -99.9% | 3,478 | $5K |
| Clearstead Advisors, LLC | 0.00% | Reduce -32.8% | 3,200 | $4K |
| Essential Partners LLC | 0.00% | Reduce -75.4% | 2,200 | $3K |
| N.E.W. Advisory Services LLC | 0.00% | No change | 1,619 | $2K |
| Bessemer Group Inc. | 0.00% | No change | 1,300 | $2K |
| Optiver Holding B.V. | 0.00% | Reduce -42.2% | 1,088 | $1K |
| Winch Advisory Services, LLC | 0.00% | No change | 1,000 | $1K |
| Harbour Investments, Inc. | 0.00% | New | 1,000 | $1K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 1,000 | $1K |
| GAMMA Investing LLC | 0.00% | New | 889 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -63.3% | 641 | $833 |
| New England Capital Financial Advisors LLC | 0.00% | No change | 475 | $618 |
| Rockefeller Capital Management L.P. | 0.00% | Add +580.3% | 415 | $539 |
| SJS Investment Consulting Inc. | 0.00% | No change | 400 | $520 |
| IFP Advisors, Inc | 0.00% | Reduce -30.0% | 361 | $469 |
| Lodestone Wealth Management LLC | 0.00% | New | 250 | $325 |
| Parallel Advisors, LLC | 0.00% | No change | 200 | $260 |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 188 | $244 |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 178 | $231 |
| Arax Advisory Partners | 0.00% | Reduce -99.6% | 129 | $168 |
| AdvisorNet Financial, Inc | 0.00% | No change | 110 | $143 |
| HighMark Wealth Management LLC | 0.00% | No change | 100 | $130 |
| Evermay Wealth Management LLC | 0.00% | No change | 100 | $130 |
| Fortitude Family Office, LLC | 0.00% | Reduce -11.2% | 79 | $103 |
| Rothschild Investment LLC | 0.00% | Add +71.9% | 55 | $72 |
| Farther Finance Advisors, LLC | 0.00% | New | 52 | $68 |
| SBI Securities Co., Ltd. | 0.00% | No change | 1 | $1 |
"% of holder's portfolio" is HRTX's weight in each manager's 13F, not the share of Heron Therapeutics Inc. the manager owns.