InsmedINSM
13F holders, Q1 2026 (March 31)675holders −3
89new positions
91sold out
9famous investors
$161.59avg. 13F price*
At the end of Q1 2026, 675 institutions reported holding Insmed Inc. (INSM) in their 13F filings, down 3 from Q4 2025. 89 opened new positions and 91 sold out. The largest holders were JPMorgan Chase & Co. ($3.7B), BlackRock, Inc. ($2.7B) and Darwin Global Management, Ltd. ($2.6B). 9 famous investors held it, including Stanley Druckenmiller (6.4% of Duquesne Family Office's portfolio), David E. Shaw (0.8% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.3% of Citadel Advisors's portfolio).
- Company
- Insmed Inc.
- CUSIP
- 457669307
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 89 | $664.4M |
| Exits | 91 | $434.7M |
All 13F filers, Q4 2025 → Q1 2026: 24,896,904 shares bought and 18,995,743 shares sold, net +5,901,161 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 675 holders
| JPMorgan Chase & Co. | 0.25% | Add +4.1% | 24,150,499 | $3.7B |
| BlackRock, Inc. | 0.05% | Add +10.7% | 16,678,146 | $2.7B |
| Darwin Global Management, Ltd. | 68.33% | Reduce -19.7% | 16,805,184 | $2.6B |
| FMR LLC | 0.11% | Add +32.6% | 13,160,167 | $2.2B |
| Vanguard Portfolio Management LLC | 0.09% | — | 10,371,802 | $1.7B |
| Vanguard Capital Management LLC | 0.04% | — | 9,642,131 | $1.6B |
| Baker Bros. Advisors LP | 6.97% | Add +12.6% | 7,421,111 | $1.2B |
| Artisan Partners Limited Partnership | 1.74% | Add +34.8% | 6,527,301 | $1.1B |
| Invesco Ltd. | 0.10% | Reduce -13.4% | 6,512,889 | $1.1B |
| D. E. Shaw & Co. | 0.78% | Add +29.3% | 5,625,825 | $919.9M |
| Capital International Investors | 0.22% | Add +8.6% | 5,595,194 | $914.9M |
| State Street Corp. | 0.03% | Add +6.7% | 5,551,699 | $907.8M |
| RTW Investments, LP | 7.88% | Add +0.0% | 4,842,880 | $791.9M |
| Geode Capital Management, LLC | 0.05% | Add +3.5% | 4,450,389 | $733.3M |
| T. Rowe Price Associates Inc. | 0.06% | Reduce -23.4% | 3,092,807 | $505.7M |
| Ameriprise Financial Inc. | 0.12% | Add +55.3% | 3,057,718 | $500.0M |
| Franklin Resources Inc. | 0.11% | Reduce -5.0% | 2,617,251 | $428.0M |
| Citadel Advisors | 0.26% | Add +88.6% | 2,182,571 | $356.9M |
| Orbis Allan Gray Ltd | 1.29% | Reduce -55.2% | 1,872,824 | $306.2M |
| UBS Group AG | 0.05% | Reduce -7.0% | 1,737,481 | $284.1M |
| Bank of America Corp. | 0.02% | Reduce -12.9% | 1,502,281 | $245.7M |
| Integral Health Asset Management, LLC | 12.98% | Add +20.0% | 1,500,000 | $245.3M |
| Westfield Capital Management Co. LP | 1.01% | Add +239.5% | 1,468,459 | $240.1M |
| Sei Investments Co. | 0.21% | Add +56.8% | 1,395,794 | $228.2M |
| Capital World Investors | 0.03% | New | 1,362,291 | $222.7M |
| Vanguard Fiduciary Trust Co. | 0.06% | — | 1,354,516 | $221.5M |
| Morgan Stanley | 0.01% | Reduce -18.4% | 1,331,542 | $217.7M |
| Northern Trust Corp. | 0.03% | Add +4.5% | 1,294,000 | $211.6M |
| Castle Hook Partners LP | 4.20% | Add +1.3% | 1,269,754 | $207.6M |
| Bank of New York Mellon Corp | 0.04% | Reduce -9.2% | 1,262,749 | $206.5M |
| Paradigm Biocapital Advisors LP | 4.19% | New | 1,254,488 | $205.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.04% | Add +28.8% | 1,215,025 | $198.7M |
| Millennium Management | 0.15% | Reduce -11.7% | 1,157,786 | $189.3M |
| Duquesne Family Office | 6.43% | Reduce -22.1% | 1,154,090 | $188.7M |
| Nomura Asset Management International Inc. | 0.32% | Reduce -3.3% | 1,143,739 | $187.0M |
| Pictet Asset Management Holding SA | 0.19% | Add +14.9% | 1,102,248 | $178.7M |
| Charles Schwab Investment Management Inc. | 0.03% | Add +4.1% | 1,069,390 | $174.9M |
| Fiera Capital Corp | 0.57% | Add +2.9% | 1,021,970 | $167.1M |
| Nwi Management LP | 10.14% | Add +2.6% | 1,014,000 | $165.8M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -24.3% | 942,646 | $154.1M |
| American Century Companies Inc. | 0.08% | Add +400.2% | 925,799 | $151.4M |
| Principal Financial Group Inc. | 0.08% | Add +18.8% | 916,464 | $149.9M |
| William Blair Investment Management, LLC | 0.49% | Reduce -26.1% | 902,666 | $147.6M |
| Adage Capital Partners Gp, L.L.C. | 0.23% | Add +200.0% | 900,000 | $147.2M |
| FIL Ltd | 0.11% | Reduce -1.1% | 828,947 | $135.5M |
| Amundi | 0.04% | Reduce -12.2% | 804,977 | $131.6M |
| Legal & General Group Plc | 0.03% | Add +45.7% | 787,079 | $128.7M |
| Raymond James Financial Inc. | 0.04% | Reduce -0.5% | 775,148 | $121.4M |
| Alliancebernstein L.P. | 0.04% | Add +7.2% | 688,734 | $119.9M |
| Hood River Capital Management LLC | 1.13% | Add +8.0% | 688,554 | $112.6M |
| AQR Capital Management | 0.05% | Add +44.3% | 675,485 | $108.8M |
| Summit Partners Public Asset Management, LLC | 4.94% | Reduce -28.1% | 653,445 | $106.9M |
| Clearbridge Investments, LLC | 0.09% | Reduce -21.4% | 643,435 | $105.2M |
| Artia Global Partners LP | 23.18% | Reduce -7.8% | 628,712 | $102.8M |
| Swiss National Bank | 0.06% | Add +8.1% | 625,912 | $102.3M |
| GW&K Investment Management, LLC | 0.90% | Add +29.1% | 623,048 | $101.9M |
| Jennison Associates LLC | 0.07% | Add +7.5% | 604,694 | $98.9M |
| BNP Paribas Financial Markets | 0.07% | Reduce -34.0% | 604,600 | $98.9M |
| Wells Fargo & Company | 0.02% | Add +1.8% | 597,384 | $97.7M |
| TimesSquare Capital Management, LLC | 1.62% | Add +19.2% | 584,798 | $95.6M |
| Deutsche Bank AG | 0.03% | Reduce -4.7% | 562,474 | $92.0M |
| Eventide Asset Management, LLC | 1.48% | Add +13.0% | 546,310 | $89.3M |
| Federated Hermes, Inc. | 0.14% | Reduce -14.9% | 538,257 | $88.0M |
| Nuveen, LLC | 0.02% | Reduce -17.8% | 534,750 | $87.4M |
| Royal Bank of Canada | 0.02% | Add +3.2% | 523,101 | $85.5M |
| Sumitomo Mitsui Trust Group, Inc. | 0.05% | Add +15.1% | 501,282 | $82.0M |
| Ensign Peak Advisors, Inc | 0.15% | Add +30.8% | 499,756 | $81.7M |
| Affinity Asset Advisors, LLC | 4.70% | Add +6.7% | 480,000 | $78.5M |
| Frontier Capital Management Co. LLC | 0.79% | Add +64.8% | 469,561 | $76.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.09% | Add +42.5% | 467,753 | $76.5M |
| Janus Henderson Group PLC | 0.03% | Reduce -47.6% | 419,304 | $68.6M |
| Samlyn Capital, LLC | 1.17% | Add +12.9% | 417,205 | $68.2M |
| Palo Alto Investors LP | 10.39% | Reduce -15.2% | 415,269 | $67.9M |
| Candriam S.C.A. | 0.34% | Add +0.2% | 401,735 | $65.7M |
| Dimensional Fund Advisors LP | 0.01% | Add +0.5% | 400,900 | $65.5M |
| Wellington Management Group LLP | 0.01% | Reduce -17.9% | 399,044 | $65.3M |
| Lord, Abbett & Co. LLC | 0.22% | Reduce -44.9% | 397,261 | $65.0M |
| Victory Capital Management Inc. | 0.04% | Reduce -38.7% | 396,245 | $64.8M |
| Polar Capital Holdings Plc | 0.26% | Add +6.9% | 368,107 | $60.2M |
| Gateway Investment Advisers LLC | 0.67% | No change | 365,000 | $59.7M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.05% | — | 360,075 | $58.9M |
| Sofinnova Investments, Inc. | 2.84% | Add +120.7% | 346,075 | $56.6M |
| California Public Employees Retirement System | 0.03% | Reduce -2.9% | 344,612 | $56.4M |
| Rock Springs Capital Management LP | 3.03% | Reduce -1.6% | 314,300 | $51.4M |
| Marshall Wace, LLP | 0.06% | Reduce -19.8% | 312,565 | $51.1M |
| National Pension Service | 0.04% | Add +11.2% | 311,881 | $51.0M |
| California State Teachers Retirement System | 0.05% | Reduce -2.3% | 303,182 | $49.6M |
| Nearwater Capital Markets, Ltd | 1.16% | Reduce -40.0% | 300,000 | $49.1M |
| Envestnet Asset Management Inc. | 0.01% | Add +8.6% | 299,925 | $49.0M |
| Bridgewater Associates | 0.22% | New | 295,579 | $48.3M |
| New York State Common Retirement Fund | 0.07% | Add +6.3% | 293,546 | $48.0M |
| Allspring Global Investments Holdings, LLC | 0.08% | Add +28.5% | 282,734 | $46.6M |
| ProShare Advisors LLC | 0.07% | Reduce -16.9% | 283,141 | $46.3M |
| Aberdeen Group plc | 0.07% | Add +9.4% | 277,016 | $45.3M |
| Barclays PLC | 0.02% | Reduce -38.0% | 275,731 | $45.1M |
| Rhumbline Advisers | 0.04% | Add +1.6% | 272,615 | $44.6M |
| Neuberger Berman Group LLC | 0.03% | Add +30.2% | 270,700 | $44.3M |
| Tang Capital Management LLC | 2.16% | Add +333.3% | 260,000 | $42.5M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.03% | Add +14.8% | 255,247 | $41.7M |
| First Turn Management, LLC | 4.54% | Reduce -6.0% | 248,475 | $40.6M |
"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.