InsmedINSM
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 438 institutions reported holding Insmed Inc. (INSM) in their 13F filings, up 24 from Q3 2024. 49 opened new positions and 43 sold out. The largest holders were Vanguard Group Inc. ($1.3B), BlackRock, Inc. ($1.1B) and Darwin Global Management, Ltd. ($894.8M). 8 famous investors held it, including Stanley Druckenmiller (1.2% of Duquesne Family Office's portfolio), George Soros (0.8% of Soros Fund Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Insmed Inc.
- CUSIP
- 457669307
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 49 | $192.7M |
| Exits | 43 | $235.3M |
All 13F filers, Q3 2024 → Q4 2024: 18,579,689 shares bought and 14,975,395 shares sold, net +3,604,294 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 438 holders
| Vanguard Group Inc. | 0.02% | Add +6.3% | 18,218,973 | $1.3B |
| BlackRock, Inc. | 0.02% | Add +7.1% | 16,032,944 | $1.1B |
| Darwin Global Management, Ltd. | 84.75% | Add +23.5% | 12,960,538 | $894.8M |
| T. Rowe Price Associates Inc. | 0.10% | Add +1.0% | 12,704,410 | $877.1M |
| Capital International Investors | 0.09% | Add +9.1% | 7,116,997 | $491.4M |
| State Street Corp. | 0.02% | Reduce -1.2% | 6,106,153 | $421.6M |
| Baker Bros. Advisors LP | 3.74% | Add +13.4% | 5,006,863 | $345.7M |
| FMR LLC | 0.02% | Reduce -32.5% | 4,856,249 | $335.3M |
| Geode Capital Management, LLC | 0.02% | Add +7.2% | 4,087,143 | $282.2M |
| JPMorgan Chase & Co. | 0.02% | Reduce -0.6% | 3,286,248 | $226.9M |
| Artisan Partners Limited Partnership | 0.33% | Add +8.4% | 3,126,339 | $215.8M |
| RTW Investments, LP | 3.15% | Reduce -7.9% | 3,014,558 | $208.1M |
| Ameriprise Financial Inc. | 0.05% | Add +10.4% | 2,850,097 | $196.8M |
| FIL Ltd | 0.17% | Add +8.1% | 2,638,160 | $182.1M |
| William Blair Investment Management, LLC | 0.41% | Add +0.5% | 2,433,443 | $168.0M |
| Alliancebernstein L.P. | 0.06% | Reduce -3.5% | 2,363,561 | $163.2M |
| Macquarie Group Ltd. | 0.19% | Add +1.2% | 2,313,159 | $159.7M |
| Franklin Resources Inc. | 0.04% | Reduce -20.6% | 2,160,103 | $149.1M |
| T. Rowe Price Investment Management, Inc. | 0.08% | Reduce -12.9% | 1,982,707 | $136.9M |
| Pictet Asset Management Holding SA | 0.15% | Add +5.2% | 1,959,718 | $135.3M |
| Clearbridge Investments, LLC | 0.11% | Add +3.9% | 1,878,450 | $129.7M |
| Norges Bank | 0.02% | Add +10.7% | 1,833,810 | $126.6M |
| Principal Financial Group Inc. | 0.07% | Reduce -2.9% | 1,817,643 | $125.5M |
| Northern Trust Corp. | 0.02% | Add +19.9% | 1,750,642 | $120.9M |
| Goldman Sachs Group Inc. | 0.02% | Add +23.5% | 1,720,049 | $118.8M |
| Adage Capital Partners Gp, L.L.C. | 0.20% | Add +59.6% | 1,647,562 | $113.7M |
| Montanova Capital, LLC | 4.12% | Reduce -1.5% | 1,611,561 | $111.3M |
| Palo Alto Investors LP | 17.15% | Reduce -17.4% | 1,603,465 | $110.7M |
| Integral Health Asset Management, LLC | 9.46% | Add +6.9% | 1,550,000 | $107.0M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +7.1% | 1,546,607 | $106.8M |
| Hood River Capital Management LLC | 1.56% | Add +3.6% | 1,525,628 | $105.3M |
| Lord, Abbett & Co. LLC | 0.33% | Reduce -0.9% | 1,457,210 | $100.6M |
| Janus Henderson Group PLC | 0.05% | Reduce -2.9% | 1,445,696 | $99.8M |
| Bank of New York Mellon Corp | 0.02% | Reduce -2.2% | 1,438,466 | $99.3M |
| Morgan Stanley | 0.01% | Add +2.3% | 1,351,365 | $93.3M |
| Nuveen Asset Management, LLC | 0.02% | Add +19.4% | 1,266,630 | $87.4M |
| Loomis Sayles & Co. L P | 0.10% | Reduce -2.9% | 1,174,791 | $81.1M |
| GW&K Investment Management, LLC | 0.67% | Reduce -1.6% | 1,135,393 | $78.4M |
| Bank of America Corp. | 0.01% | Reduce -4.0% | 1,107,666 | $76.5M |
| Eventide Asset Management, LLC | 1.38% | Add +21.5% | 1,100,993 | $76.0M |
| Marshall Wace, LLP | 0.09% | Add +38.0% | 1,064,215 | $73.5M |
| Invesco Ltd. | 0.01% | Reduce -4.4% | 1,016,090 | $70.2M |
| Westfield Capital Management Co. LP | 0.28% | Add +272.8% | 938,551 | $64.8M |
| Alyeska Investment Group, L.P. | 0.24% | Add +25.2% | 935,779 | $64.6M |
| Vestal Point Capital, LP | 3.68% | Reduce -43.8% | 900,000 | $62.1M |
| American Century Companies Inc. | 0.03% | Add +12.3% | 812,780 | $56.1M |
| Jennison Associates LLC | 0.03% | Add +0.6% | 773,813 | $53.4M |
| Wellington Management Group LLP | 0.01% | Reduce -21.8% | 752,226 | $51.9M |
| Polar Capital Holdings Plc | 0.28% | Add +7.3% | 730,000 | $50.4M |
| Novo Holdings A/S | 3.03% | No change | 724,666 | $50.0M |
| Millennium Management | 0.04% | Add +23.8% | 699,006 | $48.3M |
| Holocene Advisors, LP | 0.15% | New | 687,712 | $47.5M |
| Emerald Advisers, LLC | 1.83% | Reduce -0.8% | 684,636 | $47.3M |
| TimesSquare Capital Management, LLC | 0.69% | Add +41.4% | 684,384 | $47.2M |
| Brown Advisory Inc. | 0.06% | New | 662,997 | $45.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.11% | Add +28.6% | 654,901 | $45.2M |
| Long Focus Capital Management, LLC | 3.44% | Add +3.5% | 650,800 | $44.9M |
| Cormorant Asset Management, LP | 2.46% | Add +30.0% | 650,000 | $44.9M |
| Summit Partners Public Asset Management, LLC | 1.48% | Add +10.5% | 638,848 | $44.1M |
| Two Sigma Investments, LP | 0.10% | Reduce -25.9% | 593,996 | $41.0M |
| Duquesne Family Office | 1.15% | Add +2867.3% | 593,470 | $41.0M |
| Fiera Capital Corp | 0.13% | Reduce -1.8% | 581,854 | $40.2M |
| Rock Springs Capital Management LP | 1.45% | Reduce -19.5% | 550,000 | $38.0M |
| Voya Investment Management LLC | 0.05% | Reduce -26.4% | 548,867 | $37.9M |
| Ensign Peak Advisors, Inc | 0.06% | Add +9.3% | 529,049 | $36.5M |
| TD Asset Management Inc | 0.03% | Add +2.7% | 526,890 | $36.4M |
| Assenagon Asset Management S.A. | 0.07% | Reduce -38.7% | 525,193 | $36.3M |
| Eagle Health Investments LP | 8.69% | No change | 513,700 | $35.5M |
| D. E. Shaw & Co. | 0.04% | Add +662.4% | 508,787 | $35.1M |
| Deutsche Bank AG | 0.01% | Add +76.6% | 488,966 | $33.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +15.1% | 486,847 | $33.6M |
| First Light Asset Management, LLC | 3.11% | Reduce -31.8% | 470,192 | $32.5M |
| Soros Fund Management | 0.79% | Reduce -4.9% | 455,089 | $31.4M |
| Candriam S.C.A. | 0.18% | Reduce -4.8% | 453,520 | $31.3M |
| Logos Global Management LP | 3.64% | New | 450,000 | $31.1M |
| First Turn Management, LLC | 5.53% | Add +25.4% | 446,980 | $30.9M |
| Susquehanna International Group, LLP | 0.05% | Add +69.9% | 444,435 | $30.7M |
| Frontier Capital Management Co. LLC | 0.29% | Reduce -26.8% | 435,006 | $30.0M |
| Allspring Global Investments Holdings, LLC | 0.05% | Add +8.4% | 423,094 | $29.6M |
| Victory Capital Management Inc. | 0.03% | Reduce -9.9% | 410,577 | $28.3M |
| UBS Group AG | 0.01% | Add +30.9% | 405,725 | $28.0M |
| Emerald Mutual Fund Advisers Trust | 1.68% | Reduce -17.9% | 400,624 | $27.7M |
| MPM Bioimpact LLC | 3.82% | Reduce -36.7% | 389,611 | $26.9M |
| Qube Research & Technologies Ltd | 0.04% | Reduce -20.5% | 389,033 | $26.9M |
| Fred Alger Management, LLC | 0.13% | Reduce -14.8% | 385,460 | $26.6M |
| Silverarc Capital Management, LLC | 5.75% | Add +7.1% | 372,230 | $25.7M |
| Raymond James Financial Inc. | 0.01% | — | 363,446 | $25.1M |
| Sei Investments Co. | 0.03% | Add +8.7% | 362,616 | $25.0M |
| Barclays PLC | 0.01% | Add +6.7% | 354,436 | $24.5M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -4.4% | 350,939 | $24.2M |
| B Group, Inc. | 14.77% | — | 350,000 | $24.2M |
| Caption Management, LLC | 1.00% | Add +253.2% | 348,994 | $24.1M |
| C WorldWide Group Holding A/S | 0.29% | No change | 343,110 | $23.7M |
| Octagon Capital Advisors LP | 3.90% | Reduce -24.0% | 332,000 | $22.9M |
| Two Sigma Advisers, LP | 0.05% | Reduce -16.9% | 326,500 | $22.5M |
| Citadel Advisors | 0.02% | Reduce -3.8% | 323,735 | $22.4M |
| Swiss National Bank | 0.01% | Add +6.2% | 321,100 | $22.2M |
| Soleus Capital Management, L.P. | 1.67% | Add +958.0% | 320,272 | $22.1M |
| New York State Common Retirement Fund | 0.03% | Add +8.5% | 317,753 | $21.9M |
| Panagora Asset Management Inc. | 0.10% | Add +9.2% | 317,162 | $21.9M |
"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.