InsmedINSM
13F holders, Q2 2025 (June 30)516holders +75
127new positions
50sold out
10famous investors
$100.53avg. 13F price*
At the end of Q2 2025, 516 institutions reported holding Insmed Inc. (INSM) in their 13F filings, up 75 from Q1 2025. 127 opened new positions and 50 sold out. The largest holders were Darwin Global Management, Ltd. ($1.9B), Vanguard Group Inc. ($1.8B) and JPMorgan Chase & Co. ($1.6B). 10 famous investors held it, including Stanley Druckenmiller (5.8% of Duquesne Family Office's portfolio), Lee Ainslie (1.2% of Maverick Capital's portfolio) and David E. Shaw (0.4% of D. E. Shaw & Co.'s portfolio).
- Company
- Insmed Inc.
- CUSIP
- 457669307
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 127 | $878.6M |
| Exits | 50 | $380.2M |
All 13F filers, Q1 2025 → Q2 2025: 43,637,089 shares bought and 32,608,666 shares sold, net +11,028,423 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 516 holders
| Darwin Global Management, Ltd. | 80.75% | Add +25.6% | 19,344,621 | $1.9B |
| Vanguard Group Inc. | 0.03% | Reduce -3.4% | 17,644,492 | $1.8B |
| JPMorgan Chase & Co. | 0.11% | Add +146.1% | 15,636,399 | $1.6B |
| T. Rowe Price Associates Inc. | 0.13% | Reduce -13.1% | 11,230,705 | $1.1B |
| BlackRock, Inc. | 0.02% | Reduce -30.6% | 11,142,432 | $1.1B |
| Baker Bros. Advisors LP | 7.53% | Add +43.4% | 7,712,900 | $776.2M |
| Capital International Investors | 0.13% | Add +3.9% | 7,478,859 | $752.7M |
| FMR LLC | 0.03% | Add +50.0% | 5,093,261 | $512.6M |
| State Street Corp. | 0.02% | Reduce -25.6% | 4,277,888 | $430.5M |
| D. E. Shaw & Co. | 0.37% | Add +365.7% | 3,422,619 | $344.5M |
| Geode Capital Management, LLC | 0.02% | Reduce -22.1% | 3,340,707 | $336.3M |
| Artisan Partners Limited Partnership | 0.50% | Add +3.0% | 3,314,341 | $333.6M |
| RTW Investments, LP | 4.42% | Add +2.3% | 3,084,558 | $310.4M |
| Ameriprise Financial Inc. | 0.07% | Add +0.2% | 2,957,973 | $297.7M |
| Adage Capital Partners Gp, L.L.C. | 0.48% | Reduce -17.0% | 2,859,452 | $287.8M |
| Franklin Resources Inc. | 0.06% | Add +9.4% | 2,350,133 | $236.5M |
| Janus Henderson Group PLC | 0.11% | Add +48.4% | 2,293,142 | $230.8M |
| Duquesne Family Office | 5.79% | Add +64.6% | 2,253,435 | $226.8M |
| Millennium Management | 0.20% | Add +212.4% | 2,121,717 | $213.5M |
| Holocene Advisors, LP | 0.50% | Reduce -0.5% | 2,016,806 | $203.0M |
| Norges Bank | 0.02% | Add +11.0% | 1,934,899 | $194.7M |
| Invesco Ltd. | 0.03% | Add +5.9% | 1,896,333 | $190.8M |
| Goldman Sachs Group Inc. | 0.03% | Add +29.1% | 1,810,895 | $182.2M |
| Deep Track Capital, LP | 5.66% | Add +587.0% | 1,750,000 | $176.1M |
| William Blair Investment Management, LLC | 0.44% | Reduce -28.0% | 1,665,602 | $167.6M |
| Integral Health Asset Management, LLC | 15.04% | Add +3.2% | 1,600,000 | $161.0M |
| Pictet Asset Management Holding SA | 0.16% | Reduce -22.8% | 1,553,628 | $156.2M |
| Lord, Abbett & Co. LLC | 0.52% | Add +14.5% | 1,545,859 | $155.6M |
| Citadel Advisors | 0.14% | Add +309.1% | 1,533,277 | $154.3M |
| Orbis Allan Gray Ltd | 0.75% | New | 1,524,134 | $153.4M |
| Clearbridge Investments, LLC | 0.12% | Reduce -22.1% | 1,424,562 | $143.4M |
| Jane Street Group, LLC | 0.22% | Add +985.9% | 1,352,922 | $136.2M |
| Principal Financial Group Inc. | 0.07% | Reduce -23.2% | 1,348,027 | $135.7M |
| Alliancebernstein L.P. | 0.04% | Reduce -44.6% | 1,343,212 | $135.2M |
| Westfield Capital Management Co. LP | 0.57% | Reduce -4.8% | 1,339,288 | $134.8M |
| Charles Schwab Investment Management Inc. | 0.02% | Reduce -18.9% | 1,299,568 | $130.8M |
| GW&K Investment Management, LLC | 1.15% | Reduce -7.5% | 1,274,316 | $128.2M |
| Bank of America Corp. | 0.01% | Reduce -9.3% | 1,226,737 | $123.5M |
| Bank of New York Mellon Corp | 0.02% | Add +3.5% | 1,197,473 | $120.5M |
| Eventide Asset Management, LLC | 2.11% | Add +1.3% | 1,196,494 | $120.4M |
| FIL Ltd | 0.10% | Reduce -51.2% | 1,165,464 | $117.3M |
| Wellington Management Group LLP | 0.02% | Reduce -5.2% | 1,159,699 | $116.7M |
| Macquarie Group Ltd. | 0.14% | Reduce -52.1% | 1,130,923 | $113.8M |
| Marshall Wace, LLP | 0.13% | Add +59.9% | 1,113,361 | $112.0M |
| Qube Research & Technologies Ltd | 0.15% | New | 1,082,050 | $108.9M |
| Morgan Stanley | 0.01% | Reduce -1.5% | 1,043,791 | $105.0M |
| Summit Partners Public Asset Management, LLC | 3.96% | Add +43.2% | 1,008,937 | $101.5M |
| Northern Trust Corp. | 0.01% | Reduce -42.4% | 969,800 | $97.6M |
| Hood River Capital Management LLC | 1.26% | Reduce -42.3% | 899,603 | $90.5M |
| TimesSquare Capital Management, LLC | 1.27% | Reduce -17.9% | 873,491 | $87.9M |
| Palo Alto Investors LP | 18.52% | Reduce -12.4% | 865,113 | $87.1M |
| Maverick Capital | 1.24% | Add +89.2% | 804,133 | $80.9M |
| Loomis Sayles & Co. L P | 0.10% | Reduce -21.4% | 793,569 | $79.9M |
| Raymond James Financial Inc. | 0.03% | Add +91.8% | 784,551 | $79.0M |
| BNP Paribas Financial Markets | 0.06% | Add +63.4% | 754,160 | $75.9M |
| Artia Global Partners LP | 19.48% | Add +136.5% | 752,712 | $75.8M |
| Fiera Capital Corp | 0.26% | Add +29.1% | 748,037 | $75.3M |
| HRT Financial LP | 0.32% | New | 729,597 | $73.4M |
| Nwi Management LP | 6.65% | Add +60.0% | 720,000 | $72.5M |
| Jennison Associates LLC | 0.04% | Reduce -4.4% | 715,606 | $72.0M |
| Deerfield Management Company, L.P. | 1.43% | Add +53.0% | 700,700 | $70.5M |
| Polar Capital Holdings Plc | 0.37% | Reduce -4.2% | 697,960 | $70.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +29.0% | 695,961 | $70.0M |
| Novo Holdings A/S | 4.83% | Reduce -6.2% | 680,000 | $68.4M |
| Perceptive Advisors LLC | 2.46% | Add +27.7% | 650,252 | $65.4M |
| Alyeska Investment Group, L.P. | 0.22% | Reduce -17.9% | 603,702 | $60.8M |
| Nuveen, LLC | 0.02% | Reduce -49.1% | 588,987 | $59.3M |
| Brown Advisory Inc. | 0.08% | Reduce -13.8% | 579,846 | $58.4M |
| Ensign Peak Advisors, Inc | 0.10% | Reduce -4.2% | 564,389 | $56.8M |
| Cormorant Asset Management, LP | 4.05% | Add +2.9% | 540,000 | $54.3M |
| Rock Springs Capital Management LP | 3.30% | Add +1.8% | 525,000 | $52.8M |
| Long Focus Capital Management, LLC | 3.38% | Reduce -17.5% | 520,200 | $52.4M |
| Alkeon Capital Management LLC | 0.24% | New | 500,000 | $50.3M |
| Point72 Asset Management | 0.12% | New | 490,667 | $49.4M |
| Affinity Asset Advisors, LLC | 7.37% | Add +239.3% | 475,000 | $47.8M |
| Castle Hook Partners LP | 0.67% | New | 452,656 | $45.6M |
| Candriam S.C.A. | 0.26% | Reduce -3.7% | 438,688 | $44.2M |
| Sei Investments Co. | 0.05% | Add +9.5% | 433,628 | $43.6M |
| Eagle Health Investments LP | 10.65% | Reduce -3.3% | 428,600 | $43.1M |
| Royal Bank of Canada | 0.01% | Add +74.4% | 427,801 | $43.1M |
| New York State Common Retirement Fund | 0.06% | Add +20.3% | 427,753 | $43.0M |
| Dimensional Fund Advisors LP | 0.01% | Add +10.7% | 411,744 | $41.4M |
| Voya Investment Management LLC | 0.05% | Reduce -30.4% | 407,679 | $41.0M |
| TD Asset Management Inc | 0.03% | Reduce -21.3% | 395,194 | $39.8M |
| Two Sigma Investments, LP | 0.07% | Reduce -7.5% | 376,508 | $37.9M |
| First Turn Management, LLC | 7.00% | Reduce -7.2% | 372,672 | $37.5M |
| Envestnet Asset Management Inc. | 0.01% | Add +12.5% | 365,827 | $36.8M |
| Patient Square Capital LP | 13.02% | Add +8.6% | 358,800 | $36.1M |
| Swiss National Bank | 0.02% | Add +5.5% | 347,400 | $35.0M |
| Weiss Asset Management LP | 0.64% | New | 339,825 | $34.2M |
| Los Angeles Capital Management LLC | 0.12% | Add +2637.5% | 330,800 | $33.3M |
| Sofinnova Investments, Inc. | 2.15% | Add +3.2% | 313,923 | $31.6M |
| Voloridge Investment Management, LLC | 0.12% | Add +11594.2% | 313,053 | $31.5M |
| Aberdeen Group plc | 0.05% | Reduce -7.9% | 309,749 | $31.2M |
| Renaissance Technologies | 0.04% | New | 308,687 | $31.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.07% | Reduce -50.8% | 302,065 | $30.4M |
| Allspring Global Investments Holdings, LLC | 0.05% | Reduce -30.6% | 304,310 | $29.7M |
| UBS Group AG | 0.01% | Reduce -38.6% | 293,454 | $29.5M |
| Cubist Systematic Strategies, LLC | 0.31% | New | 283,102 | $28.5M |
| C WorldWide Group Holding A/S | 0.37% | Reduce -15.6% | 271,110 | $27.3M |
"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.