Iovance BiotherapeuticsIOVA
13F holders, Q4 2025 (December 31)263holders +10
43new positions
36sold out
6famous investors
$2.73avg. 13F price*
At the end of Q4 2025, 263 institutions reported holding Iovance Biotherapeutics Inc. (IOVA) in their 13F filings, up 10 from Q3 2025. 43 opened new positions and 36 sold out. The largest holders were BlackRock, Inc. ($80.6M), MHR Fund Management LLC ($79.1M) and Vanguard Group Inc. ($74.3M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Iovance Biotherapeutics Inc.
- CUSIP
- 462260100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 43 | $10.6M |
| Exits | 36 | $7.7M |
All 13F filers, Q3 2025 → Q4 2025: 61,539,415 shares bought and 13,220,758 shares sold, net +48,318,657 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 263 holders
| BlackRock, Inc. | 0.00% | Add +13.7% | 29,518,125 | $80.6M |
| MHR Fund Management LLC | 6.81% | No change | 28,967,103 | $79.1M |
| Vanguard Group Inc. | 0.00% | Add +13.1% | 27,207,079 | $74.3M |
| State Street Corp. | 0.00% | Add +51.5% | 20,161,445 | $55.0M |
| Bank of America Corp. | 0.00% | Add +127.4% | 14,277,813 | $39.0M |
| Invenomic Capital Management LP | 1.58% | Add +13.4% | 11,959,505 | $32.6M |
| Morgan Stanley | 0.00% | Add +64.7% | 9,191,840 | $25.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +30.9% | 8,607,564 | $23.5M |
| Long Focus Capital Management, LLC | 1.17% | Reduce -5.7% | 8,600,000 | $23.5M |
| Geode Capital Management, LLC | 0.00% | Add +16.4% | 7,991,640 | $21.8M |
| Palo Alto Investors LP | 2.70% | Reduce -6.6% | 7,116,676 | $19.4M |
| Millennium Management | 0.01% | Add +49.2% | 6,585,532 | $18.0M |
| Susquehanna International Group, LLP | 0.02% | Add +49.7% | 4,948,614 | $13.5M |
| Two Sigma Investments, LP | 0.02% | Add +60.5% | 4,397,989 | $12.0M |
| HRT Financial LP | 0.04% | Add +1078.3% | 4,356,010 | $11.9M |
| D. E. Shaw & Co. | 0.01% | Add +4925.4% | 3,829,795 | $10.5M |
| Jane Street Group, LLC | 0.01% | Add +153.5% | 3,583,810 | $9.8M |
| Citadel Advisors | 0.01% | Reduce -17.7% | 3,143,091 | $8.6M |
| Two Sigma Advisers, LP | 0.02% | Add +184.7% | 3,015,000 | $8.2M |
| JPMorgan Chase & Co. | 0.00% | Add +145.3% | 3,001,502 | $8.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +9.9% | 2,753,343 | $7.5M |
| Northern Trust Corp. | 0.00% | Add +4.8% | 2,579,594 | $7.0M |
| Wells Fargo & Company | 0.00% | Add +31.4% | 1,993,337 | $5.4M |
| Orion Investment Co | 1.54% | Add +0.3% | 1,856,934 | $5.1M |
| Rhenman & Partners Asset Management AB | 0.41% | Add +45.3% | 1,595,327 | $4.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -45.5% | 1,539,110 | $4.2M |
| B Group, Inc. | 3.03% | No change | 1,500,000 | $4.1M |
| Rice Hall James & Associates, LLC | 0.21% | Reduce -1.8% | 1,425,088 | $3.9M |
| Nuveen, LLC | 0.00% | Add +10.8% | 1,385,988 | $3.8M |
| C WorldWide Group Holding A/S | 0.06% | No change | 1,260,000 | $3.4M |
| Invesco Ltd. | 0.00% | Add +32.4% | 1,251,665 | $3.4M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -42.1% | 1,191,828 | $3.3M |
| Barclays PLC | 0.00% | Add +20.3% | 1,127,157 | $3.1M |
| Mirador Capital Partners LP | 0.39% | Add +100.9% | 1,034,544 | $2.8M |
| Bank of New York Mellon Corp | 0.00% | Add +18.4% | 955,467 | $2.6M |
| Susquehanna Portfolio Strategies, LLC | 0.04% | Add +0.3% | 914,449 | $2.5M |
| Gsa Capital Partners LLP | 0.21% | Add +1002.0% | 872,985 | $2.4M |
| Walleye Capital LLC | 0.01% | Add +2143.2% | 822,754 | $2.2M |
| UBS Group AG | 0.00% | Reduce -18.4% | 764,154 | $2.1M |
| Aberdeen Group plc | 0.00% | Add +25.1% | 759,522 | $2.1M |
| Rafferty Asset Management, LLC | 0.01% | Add +46.3% | 706,450 | $1.9M |
| Deutsche Bank AG | 0.00% | Add +7.0% | 690,416 | $1.9M |
| QVT Financial LP | 0.18% | No change | 678,564 | $1.9M |
| Renaissance Technologies | 0.00% | New | 651,000 | $1.8M |
| Voleon Capital Management LP | 0.04% | Add +350.3% | 630,257 | $1.7M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | Add +379.8% | 628,537 | $1.7M |
| LPL Financial LLC | 0.00% | Add +1.9% | 623,072 | $1.7M |
| Royal Bank of Canada | 0.00% | Reduce -60.9% | 608,459 | $1.7M |
| Swiss National Bank | 0.00% | Add +17.1% | 606,456 | $1.7M |
| Woodline Partners LP | 0.01% | No change | 567,680 | $1.5M |
| Qube Research & Technologies Ltd | 0.00% | New | 564,519 | $1.5M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 100,000 | $1.5M |
| Brevan Howard Capital Management LP | 0.03% | Add +93.2% | 525,519 | $1.4M |
| XTX Topco Ltd | 0.04% | Add +148.4% | 522,934 | $1.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -2.5% | 469,706 | $1.3M |
| Rhumbline Advisers | 0.00% | Add +17.1% | 461,284 | $1.3M |
| Cresset Asset Management, LLC | 0.01% | Add +140.3% | 457,786 | $1.2M |
| Raiffeisen Bank International AG | 0.02% | Add +87.5% | 450,000 | $1.2M |
| Algert Global LLC | 0.02% | New | 433,999 | $1.2M |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Reduce -24.6% | 410,206 | $1.1M |
| Raymond James Financial Inc. | 0.00% | Add +20.3% | 404,441 | $1.1M |
| CM Management, LLC | 0.92% | Reduce -42.9% | 400,000 | $1.1M |
| Stifel Financial Corp. | 0.00% | Reduce -5.7% | 329,815 | $900K |
| Simplex Trading, LLC | 0.03% | Add +16.6% | 329,063 | $898K |
| Quadrature Capital Ltd | 0.01% | New | 318,703 | $870K |
| Kennondale Capital Management LLC | 0.64% | No change | 318,188 | $869K |
| Jain Global LLC | 0.01% | New | 312,096 | $852K |
| Virtus Investment Advisers, LLC | 0.23% | Add +61.5% | 310,641 | $848K |
| Corsair Capital Management, L.P. | 0.14% | New | 300,000 | $819K |
| California State Teachers Retirement System | 0.00% | Add +18.0% | 295,997 | $808K |
| ExodusPoint Capital Management, LP | 0.01% | Add +568.2% | 281,477 | $768K |
| Profund Advisors LLC | 0.02% | Add +149.7% | 260,660 | $712K |
| Alliancebernstein L.P. | 0.00% | No change | 258,890 | $707K |
| Legal & General Group Plc | 0.00% | Add +1.6% | 258,676 | $706K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +2.8% | 231,443 | $637K |
| Scientech Research LLC | 0.36% | New | 211,477 | $577K |
| Russell Investments Group, Ltd. | 0.00% | Add +195.7% | 198,043 | $541K |
| Parametrica Management Ltd | 0.82% | No change | 195,878 | $535K |
| Leonteq Securities AG | 0.03% | Add +105.3% | 195,000 | $532K |
| Engineers Gate Manager LP | 0.01% | New | 194,691 | $532K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +26.9% | 183,968 | $504K |
| HSBC Holdings PLC | 0.00% | Add +651.5% | 180,541 | $497K |
| Capital Fund Management S.A. | 0.00% | Reduce -39.9% | 181,074 | $494K |
| Tudor Investment Corporation | 0.00% | Add +47.4% | 179,494 | $490K |
| MetLife Investment Management, LLC | 0.00% | Add +20.5% | 170,782 | $466K |
| Group One Trading LLC | 0.01% | Reduce -60.8% | 168,677 | $460K |
| EFG International AG | 0.01% | — | 168,000 | $459K |
| Creative Planning | 0.00% | Add +59.9% | 158,653 | $433K |
| Baird Financial Group, Inc. | 0.00% | Reduce -2.5% | 157,540 | $430K |
| Perceptive Advisors LLC | 0.01% | New | 152,714 | $417K |
| Quantitative Investment Management, LLC | 0.04% | New | 138,583 | $378K |
| Intech Investment Management LLC | 0.00% | Add +8.7% | 136,763 | $373K |
| Intellectus Partners, LLC | 0.07% | Add +1.1% | 132,446 | $362K |
| Portland Investment Counsel Inc. | 0.11% | No change | 130,000 | $355K |
| American Century Companies Inc. | 0.00% | Add +353.5% | 129,088 | $352K |
| MML Investors Services, LLC | 0.00% | New | 111,848 | $305K |
| AQR Capital Management | 0.00% | Add +9.1% | 110,591 | $302K |
| Sugar Maple Asset Management, LLC | 0.20% | New | 110,000 | $300K |
| State of Wisconsin Investment Board | 0.00% | Reduce -4.4% | 109,997 | $300K |
| Sei Investments Co. | 0.00% | Add +268.6% | 105,636 | $288K |
"% of holder's portfolio" is IOVA's weight in each manager's 13F, not the share of Iovance Biotherapeutics Inc. the manager owns.