Iovance BiotherapeuticsIOVA

13F holders, Q4 2025 (December 31)
263holders +10
43new positions
36sold out
6famous investors
$2.73avg. 13F price*

At the end of Q4 2025, 263 institutions reported holding Iovance Biotherapeutics Inc. (IOVA) in their 13F filings, up 10 from Q3 2025. 43 opened new positions and 36 sold out. The largest holders were BlackRock, Inc. ($80.6M), MHR Fund Management LLC ($79.1M) and Vanguard Group Inc. ($74.3M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Iovance Biotherapeutics Inc.
CUSIP
462260100
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 273Q1 2024Q2 2024: 295Q2 2024Q3 2024: 286Q3 2024Q4 2024: 301Q4 2024Q1 2025: 302Q1 2025Q2 2025: 254Q2 2025Q3 2025: 253Q3 2025Q4 2025: 263Q4 2025Q1 2026: 286Q1 2026Q2 2026: 293Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions43$10.6M
Exits36$7.7M

All 13F filers, Q3 2025 → Q4 2025: 61,539,415 shares bought and 13,220,758 shares sold, net +48,318,657 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 263 holders

BlackRock, Inc. 0.00% Add +13.7% 29,518,125 $80.6M
MHR Fund Management LLC 6.81% No change 28,967,103 $79.1M
Vanguard Group Inc. 0.00% Add +13.1% 27,207,079 $74.3M
State Street Corp. 0.00% Add +51.5% 20,161,445 $55.0M
Bank of America Corp. 0.00% Add +127.4% 14,277,813 $39.0M
Invenomic Capital Management LP 1.58% Add +13.4% 11,959,505 $32.6M
Morgan Stanley 0.00% Add +64.7% 9,191,840 $25.1M
Goldman Sachs Group Inc. 0.00% Add +30.9% 8,607,564 $23.5M
Long Focus Capital Management, LLC 1.17% Reduce -5.7% 8,600,000 $23.5M
Geode Capital Management, LLC 0.00% Add +16.4% 7,991,640 $21.8M
Palo Alto Investors LP 2.70% Reduce -6.6% 7,116,676 $19.4M
Millennium Management 0.01% Add +49.2% 6,585,532 $18.0M
Susquehanna International Group, LLP 0.02% Add +49.7% 4,948,614 $13.5M
Two Sigma Investments, LP 0.02% Add +60.5% 4,397,989 $12.0M
HRT Financial LP 0.04% Add +1078.3% 4,356,010 $11.9M
D. E. Shaw & Co. 0.01% Add +4925.4% 3,829,795 $10.5M
Jane Street Group, LLC 0.01% Add +153.5% 3,583,810 $9.8M
Citadel Advisors 0.01% Reduce -17.7% 3,143,091 $8.6M
Two Sigma Advisers, LP 0.02% Add +184.7% 3,015,000 $8.2M
JPMorgan Chase & Co. 0.00% Add +145.3% 3,001,502 $8.2M
Charles Schwab Investment Management Inc. 0.00% Add +9.9% 2,753,343 $7.5M
Northern Trust Corp. 0.00% Add +4.8% 2,579,594 $7.0M
Wells Fargo & Company 0.00% Add +31.4% 1,993,337 $5.4M
Orion Investment Co 1.54% Add +0.3% 1,856,934 $5.1M
Rhenman & Partners Asset Management AB 0.41% Add +45.3% 1,595,327 $4.4M
Dimensional Fund Advisors LP 0.00% Reduce -45.5% 1,539,110 $4.2M
B Group, Inc. 3.03% No change 1,500,000 $4.1M
Rice Hall James & Associates, LLC 0.21% Reduce -1.8% 1,425,088 $3.9M
Nuveen, LLC 0.00% Add +10.8% 1,385,988 $3.8M
C WorldWide Group Holding A/S 0.06% No change 1,260,000 $3.4M
Invesco Ltd. 0.00% Add +32.4% 1,251,665 $3.4M
T. Rowe Price Associates Inc. 0.00% Reduce -42.1% 1,191,828 $3.3M
Barclays PLC 0.00% Add +20.3% 1,127,157 $3.1M
Mirador Capital Partners LP 0.39% Add +100.9% 1,034,544 $2.8M
Bank of New York Mellon Corp 0.00% Add +18.4% 955,467 $2.6M
Susquehanna Portfolio Strategies, LLC 0.04% Add +0.3% 914,449 $2.5M
Gsa Capital Partners LLP 0.21% Add +1002.0% 872,985 $2.4M
Walleye Capital LLC 0.01% Add +2143.2% 822,754 $2.2M
UBS Group AG 0.00% Reduce -18.4% 764,154 $2.1M
Aberdeen Group plc 0.00% Add +25.1% 759,522 $2.1M
Rafferty Asset Management, LLC 0.01% Add +46.3% 706,450 $1.9M
Deutsche Bank AG 0.00% Add +7.0% 690,416 $1.9M
QVT Financial LP 0.18% No change 678,564 $1.9M
Renaissance Technologies 0.00% New 651,000 $1.8M
Voleon Capital Management LP 0.04% Add +350.3% 630,257 $1.7M
Healthcare of Ontario Pension Plan Trust Fund 0.00% Add +379.8% 628,537 $1.7M
LPL Financial LLC 0.00% Add +1.9% 623,072 $1.7M
Royal Bank of Canada 0.00% Reduce -60.9% 608,459 $1.7M
Swiss National Bank 0.00% Add +17.1% 606,456 $1.7M
Woodline Partners LP 0.01% No change 567,680 $1.5M
Qube Research & Technologies Ltd 0.00% New 564,519 $1.5M
DekaBank Deutsche Girozentrale 0.00% No change 100,000 $1.5M
Brevan Howard Capital Management LP 0.03% Add +93.2% 525,519 $1.4M
XTX Topco Ltd 0.04% Add +148.4% 522,934 $1.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -2.5% 469,706 $1.3M
Rhumbline Advisers 0.00% Add +17.1% 461,284 $1.3M
Cresset Asset Management, LLC 0.01% Add +140.3% 457,786 $1.2M
Raiffeisen Bank International AG 0.02% Add +87.5% 450,000 $1.2M
Algert Global LLC 0.02% New 433,999 $1.2M
Hennion & Walsh Asset Management, Inc. 0.04% Reduce -24.6% 410,206 $1.1M
Raymond James Financial Inc. 0.00% Add +20.3% 404,441 $1.1M
CM Management, LLC 0.92% Reduce -42.9% 400,000 $1.1M
Stifel Financial Corp. 0.00% Reduce -5.7% 329,815 $900K
Simplex Trading, LLC 0.03% Add +16.6% 329,063 $898K
Quadrature Capital Ltd 0.01% New 318,703 $870K
Kennondale Capital Management LLC 0.64% No change 318,188 $869K
Jain Global LLC 0.01% New 312,096 $852K
Virtus Investment Advisers, LLC 0.23% Add +61.5% 310,641 $848K
Corsair Capital Management, L.P. 0.14% New 300,000 $819K
California State Teachers Retirement System 0.00% Add +18.0% 295,997 $808K
ExodusPoint Capital Management, LP 0.01% Add +568.2% 281,477 $768K
Profund Advisors LLC 0.02% Add +149.7% 260,660 $712K
Alliancebernstein L.P. 0.00% No change 258,890 $707K
Legal & General Group Plc 0.00% Add +1.6% 258,676 $706K
Manufacturers Life Insurance Company, The 0.00% Add +2.8% 231,443 $637K
Scientech Research LLC 0.36% New 211,477 $577K
Russell Investments Group, Ltd. 0.00% Add +195.7% 198,043 $541K
Parametrica Management Ltd 0.82% No change 195,878 $535K
Leonteq Securities AG 0.03% Add +105.3% 195,000 $532K
Engineers Gate Manager LP 0.01% New 194,691 $532K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +26.9% 183,968 $504K
HSBC Holdings PLC 0.00% Add +651.5% 180,541 $497K
Capital Fund Management S.A. 0.00% Reduce -39.9% 181,074 $494K
Tudor Investment Corporation 0.00% Add +47.4% 179,494 $490K
MetLife Investment Management, LLC 0.00% Add +20.5% 170,782 $466K
Group One Trading LLC 0.01% Reduce -60.8% 168,677 $460K
EFG International AG 0.01% — 168,000 $459K
Creative Planning 0.00% Add +59.9% 158,653 $433K
Baird Financial Group, Inc. 0.00% Reduce -2.5% 157,540 $430K
Perceptive Advisors LLC 0.01% New 152,714 $417K
Quantitative Investment Management, LLC 0.04% New 138,583 $378K
Intech Investment Management LLC 0.00% Add +8.7% 136,763 $373K
Intellectus Partners, LLC 0.07% Add +1.1% 132,446 $362K
Portland Investment Counsel Inc. 0.11% No change 130,000 $355K
American Century Companies Inc. 0.00% Add +353.5% 129,088 $352K
MML Investors Services, LLC 0.00% New 111,848 $305K
AQR Capital Management 0.00% Add +9.1% 110,591 $302K
Sugar Maple Asset Management, LLC 0.20% New 110,000 $300K
State of Wisconsin Investment Board 0.00% Reduce -4.4% 109,997 $300K
Sei Investments Co. 0.00% Add +268.6% 105,636 $288K
Citigroup Inc. 0.00% Reduce -74.2% 105,540 $288K
Osaic Holdings, Inc. 0.00% Reduce -4.0% 102,155 $279K
Quinn Opportunity Partners LLC 0.01% Reduce -40.6% 95,000 $259K
VARCOV Co. 0.10% — 92,806 $253K
Janus Henderson Group PLC 0.00% No change 91,341 $250K
Tower Research Capital LLC (TRC) 0.01% Add +381.0% 91,348 $249K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% Reduce -20.4% 98,605 $248K
Los Angeles Capital Management LLC 0.00% Add +381.9% 119,860 $234K
Arizona State Retirement System 0.00% Add +8.4% 85,490 $233K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% Reduce -0.1% 82,250 $225K
Police & Firemen's Retirement System of New Jersey 0.00% Reduce -0.9% 76,002 $207K
ProShare Advisors LLC 0.00% Add +28.1% 73,733 $201K
New York State Common Retirement Fund 0.00% No change 72,101 $197K
Cetera Investment Advisers 0.00% Reduce -7.0% 70,674 $193K
Headlands Technologies LLC 0.02% New 70,662 $193K
Balyasny Asset Management L.P. 0.00% Reduce -24.9% 68,038 $186K
Grandfield & Dodd, LLC 0.01% Reduce -15.3% 65,930 $180K
State Board of Administration of Florida Retirement System 0.00% No change 65,451 $179K
WealthTrust Axiom LLC 0.05% Add +62.5% 65,000 $177K
China Universal Asset Management Co., Ltd. 0.01% Add +2.0% 64,686 $177K
KLP Kapitalforvaltning As 0.00% No change 62,400 $170K
Haven Capital Group, Inc. 0.15% Reduce -21.7% 59,143 $161K
SG Americas Securities, LLC 0.00% Add +59.3% 55,389 $151K
Man Group plc 0.00% Add +6.1% 54,521 $149K
Voya Investment Management LLC 0.00% Add +13.3% 53,477 $146K
TD Asset Management Inc 0.00% Reduce -61.8% 53,452 $146K
Centurion Wealth Management LLC 0.03% Reduce -1.3% 52,384 $143K
Commonwealth Equity Services, LLC 0.00% Reduce -0.3% 51,499 $141K
PNC Financial Services Group, Inc. 0.00% Reduce -0.4% 50,848 $139K
Rockefeller Capital Management L.P. 0.00% Add +187.6% 50,726 $138K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +47.1% 49,914 $136K
B. Riley Wealth Advisors, Inc. 0.01% Add +14.3% 48,000 $131K
Caitong International Asset Management Co., Ltd 0.03% Add +658.9% 47,277 $129K
Assenagon Asset Management S.A. 0.00% No change 46,842 $128K
Captrust Financial Advisors 0.00% Add +13.5% 46,812 $128K
Teacher Retirement System of Texas 0.00% Reduce -30.5% 45,047 $123K
LMR Partners LLP 0.00% No change 41,211 $113K
CANADA LIFE ASSURANCE Co 0.00% Add +20.4% 40,958 $112K
Chicago Partners Investment Group LLC 0.00% Add +0.0% 40,589 $107K
Neuberger Berman Group LLC 0.00% Add +16.8% 39,072 $107K
Victory Capital Management Inc. 0.00% Add +15.7% 38,993 $106K
Traphagen Investment Advisors LLC 0.01% No change 38,962 $106K
Delaney Dennis R 0.05% No change 38,000 $104K
Cambridge Investment Research Advisors, Inc. 0.00% Reduce -31.4% 37,893 $103K
Carnegie Investment Counsel 0.00% Reduce -2.7% 36,000 $98K
R Squared Ltd 0.04% Add +115.3% 34,533 $94K
Diversify Wealth Management, LLC 0.00% No change 40,000 $94K
Penbrook Management LLC 0.06% New 33,945 $93K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +164.8% 33,357 $91K
Gould Asset Management LLC 0.02% Add +170.4% 31,735 $87K
FMR LLC 0.00% Reduce -28.7% 31,073 $85K
Intrepid Family Office LLC 0.08% Reduce -25.0% 30,000 $82K
Optiver Holding B.V. 0.00% Add +3035.5% 29,568 $81K
Cim Investment Management Inc. 0.02% No change 29,423 $80K
GRIMES & Co WEALTH MANAGEMENT, LLC 0.00% Reduce -32.3% 29,338 $80K
First Manhattan Co. Llc. 0.00% Reduce -46.6% 28,998 $79K
DRW Securities, LLC 0.01% New 28,558 $78K
Pictet Asset Management Holding SA 0.00% No change 27,122 $74K
BNP Paribas Financial Markets 0.00% Reduce -50.7% 26,787 $73K
Farallon Capital Management, L.L.C. 0.00% No change 26,000 $71K
Flputnam Investment Management Co. 0.00% Add +27.9% 25,950 $71K
Ameritas Investment Partners, Inc. 0.00% Add +16.5% 25,414 $69K
Squarepoint Ops LLC 0.00% Reduce -42.9% 25,001 $68K
Xponance LLC 0.00% Add +19.4% 24,288 $66K
Wealth Enhancement Advisory Services, LLC 0.00% Reduce -10.0% 25,150 $64K
Brookstone Capital Management 0.00% Reduce -1.0% 22,683 $62K
Jump Financial, LLC 0.00% New 22,062 $60K
PVG Asset Management Corp. 0.12% Add +2.8% 20,960 $57K
Cibc World Markets Corp. 0.00% — 20,344 $56K
One68 Global Capital, LLC 0.65% New 20,000 $55K
Shay Capital LLC 0.01% New 20,000 $55K
Destination Wealth Management 0.00% New 20,000 $55K
Clearstead Advisors, LLC 0.00% No change 20,000 $55K
Adams Wealth Management 0.01% No change 19,227 $53K
CacheTech Inc. 0.01% No change 19,227 $53K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +37.9% 19,290 $53K
Envestnet Asset Management Inc. 0.00% Reduce -69.5% 19,209 $52K
HighTower Advisors, LLC 0.00% Add +67.9% 19,089 $52K
Legato Capital Management LLC 0.00% Add +9.6% 18,478 $50K
Sterling Capital Management LLC 0.00% Reduce -1.6% 17,725 $48K
Prudential Financial Inc. 0.00% Reduce -49.3% 17,665 $48K
Dynamic Technology Lab Private Ltd 0.01% New 16,872 $46K
Public Employees Retirement Association of Colorado 0.00% No change 16,764 $46K
Mackenzie Financial Corp. 0.00% Reduce -6.4% 16,360 $45K
Pathstone Holdings, LLC 0.00% New 16,273 $44K
Beacon Financial Advisory LLC 0.01% Reduce -20.0% 16,195 $44K
Bayesian Capital Management, LP 0.10% New 15,300 $42K
Xcelsior Advisor Partners LLC 0.02% — 15,150 $41K
Two Sigma Securities, LLC 0.01% New 14,040 $38K
HBK Sorce Advisory LLC 0.00% Add +8.7% 15,027 $38K
Swiss Life Asset Management Ltd 0.00% Add +19.8% 13,267 $36K
Choreo, LLC 0.00% Add +29.5% 13,069 $36K
Principal Financial Group Inc. 0.00% Reduce -99.6% 13,248 $36K
Rathbones Group PLC 0.00% Reduce -2.3% 12,854 $35K
Jacobs Levy Equity Management, Inc. 0.00% New 12,788 $35K
Vanguard Personalized Indexing Management, LLC 0.00% New 12,637 $34K
XML Financial, LLC 0.00% No change 12,500 $34K
Mgo One Seven LLC 0.00% Add +12.9% 12,458 $34K
Regions Financial Corp. 0.00% No change 12,000 $33K
Walleye Trading LLC 0.00% New 11,952 $33K
Arcadia Wealth Management, Inc. 0.02% Reduce -25.7% 11,700 $32K
SBI Securities Co., Ltd. 0.00% Add +169.1% 11,568 $32K
M&T Bank Corp 0.00% New 11,464 $31K
Calton & Associates, Inc. 0.00% Add +10.6% 11,206 $31K
Motley Fool Asset Management LLC 0.00% New 10,760 $29K
Granite Investment Partners, LLC 0.00% New 10,638 $29K
Arcataur Capital Management LLC 0.01% New 10,600 $29K
Steward Partners Investment Advisory, LLC 0.00% No change 10,497 $29K
Jones Financial Companies LLLP 0.00% Add +97.3% 10,341 $28K
Kestra Advisory Services, LLC 0.00% Reduce -16.4% 10,191 $28K
Federated Hermes, Inc. 0.00% Reduce -36.8% 9,551 $26K
Amalgamated Bank 0.00% Add +1.6% 9,661 $26K
Farther Finance Advisors, LLC 0.00% Reduce -44.4% 8,131 $22K
GF Fund Management Co. LTD. 0.00% Add +0.6% 7,830 $21K
FNY Investment Advisers, LLC 0.01% Reduce -8.5% 8,010 $21K
Comerica Bank 0.00% No change 7,230 $20K
Federation des caisses Desjardins du Quebec 0.00% No change 5,250 $14K
NewEdge Advisors, LLC 0.00% No change 4,935 $13K
Wealth Enhancement Trust Services, Inc. 0.00% — 4,000 $11K
Cwm, LLC 0.00% Reduce -18.1% 3,674 $10K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +44.0% 3,196 $9K
MAI Capital Management 0.00% Add +49.5% 3,141 $9K
Summit Securities Group LLC 0.00% New 2,819 $8K
GAMMA Investing LLC 0.00% New 2,813 $8K
Keating Financial Advisory Services, Inc. 0.00% — 2,500 $7K
Smartleaf Asset Management LLC 0.00% New 2,090 $6K
Northwestern Mutual Wealth Management Co. 0.00% No change 1,880 $5K
Valley National Advisers Inc. 0.00% New 1,680 $4K
Torren Management, LLC 0.00% — 1,348 $4K
Nisa Investment Advisors, LLC 0.00% Reduce -60.7% 1,278 $3K
US Bancorp \de 0.00% No change 1,147 $3K
Huntington National Bank 0.00% Add +114500.0% 1,146 $3K
Daiwa Securities Group Inc. 0.00% No change 1,006 $3K
Bell Investment Advisors, Inc 0.00% New 1,070 $3K
Hurley Capital, LLC 0.00% No change 1,000 $3K
First United Bank & Trust 0.00% No change 1,000 $3K
Navalign, LLC 0.00% New 1,000 $3K
Hoey Investments, Inc. 0.00% Reduce -50.0% 1,000 $3K
Signaturefd, LLC 0.00% Add +330.8% 784 $2K
Allworth Financial LP 0.00% Reduce -88.0% 783 $2K
EverSource Wealth Advisors, LLC 0.00% Reduce -0.9% 532 $1K
Essential Partners LLC 0.00% Reduce -3.5% 384 $1K
Rothschild Investment LLC 0.00% Reduce -1.1% 346 $945
AlphaQuest LLC 0.00% No change 315 $860
TD Private Client Wealth LLC 0.00% New 314 $857
Shelton Wealth Management, LLC 0.00% No change 300 $819
Parkside Financial Bank & Trust 0.00% New 300 $819
Optima Capital LLC 0.00% New 242 $661
Assetmark, Inc. 0.00% Reduce -98.4% 183 $500
Basecamp Wealth Advisors LLC 0.00% — 150 $410
North Star Investment Management Corp. 0.00% No change 125 $341
Caitlin John, LLC 0.00% No change 70 $191
Arax Advisory Partners 0.00% Reduce -95.2% 61 $167
IFP Advisors, Inc 0.00% Reduce -32.9% 51 $139
Basepoint Wealth LLC 0.00% New 49 $133
Aster Capital Management (DIFC) Ltd 0.00% New 25 $68
Inspire Investing, LLC 0.00% New 11 $30
Pier 88 Investment Partners LLC 0.00% No change 10 $27
Smallwood Wealth Investment Management, LLC 0.00% No change 9 $24
Dunhill Financial, LLC 0.00% New 3 $9
Hazlett, Burt & Watson, Inc. 0.00% No change 100 $0
Avion Wealth 0.00% No change 268 $0
Covestor Ltd 0.00% No change 24 $0

"% of holder's portfolio" is IOVA's weight in each manager's 13F, not the share of Iovance Biotherapeutics Inc. the manager owns.