Karyopharm TherapeuticsKPTI

13F holders, Q1 2025 (March 31)
2holders −85
0new positions
42sold out
$3.74avg. 13F price*

At the end of Q1 2025, 2 institutions reported holding Karyopharm Therapeutics Inc. (KPTI) in their 13F filings, down 85 from Q4 2024. 0 opened new positions and 42 sold out. The largest holders were Palo Alto Investors LP ($1.2M) and Birchview Capital, LP ($105K).

Company
Karyopharm Therapeutics Inc.
CUSIP
48576U106
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 114Q1 2024Q2 2024: 114Q2 2024Q3 2024: 91Q3 2024Q4 2024: 87Q4 2024Q1 2025: 2Q1 2025Q2 2025: 1Q2 2025Q3 2025: 1Q3 2025Q1 2026: 1Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions0$0
Exits42$5.5M

All 13F filers, Q4 2024 → Q1 2025: 13,081,228 shares sold, net −13,081,228 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 2 holders

Palo Alto Investors LP 0.23% Reduce -93.4% 324,032 $1.2M
Birchview Capital, LP 0.09% Reduce -93.3% 27,985 $105K

"% of holder's portfolio" is KPTI's weight in each manager's 13F, not the share of Karyopharm Therapeutics Inc. the manager owns.