Karyopharm TherapeuticsKPTI
13F holders, Q1 2024 (March 31)114holders
5famous investors
$1.51avg. 13F price*
At the end of Q1 2024, 114 institutions reported holding Karyopharm Therapeutics Inc. (KPTI) in their 13F filings. The largest holders were BlackRock Inc. ($14.3M), Vanguard Group Inc. ($12.6M) and Avidity Partners Management LP ($12.5M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Karyopharm Therapeutics Inc.
- CUSIP
- 48576U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 18 | $8.1M |
| Exits | 20 | $2.4M |
Ownership 114 holders
| BlackRock Inc. | 0.00% | Reduce -6.2% | 9,447,678 | $14.3M |
| Vanguard Group Inc. | 0.00% | Reduce -4.3% | 8,338,401 | $12.6M |
| Avidity Partners Management LP | 0.45% | No change | 8,298,570 | $12.5M |
| Palo Alto Investors LP | 0.87% | No change | 5,102,193 | $7.7M |
| Eversept Partners, LP | 0.57% | New | 5,016,320 | $7.6M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Add +110.4% | 3,500,000 | $5.3M |
| Citadel Advisors | 0.00% | Add +0.1% | 3,105,069 | $4.7M |
| Marshall Wace, LLP | 0.01% | Add +34.7% | 2,595,599 | $3.9M |
| Geode Capital Management, LLC | 0.00% | Add +5.8% | 2,520,105 | $3.8M |
| State Street Corp. | 0.00% | Add +11.3% | 2,285,788 | $3.5M |
| BNP Paribas Financial Markets | 0.00% | Add +0.3% | 1,773,758 | $2.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +16.3% | 1,508,262 | $2.3M |
| C WorldWide Group Holding A/S | 0.03% | No change | 1,500,000 | $2.3M |
| JPMorgan Chase & Co. | 0.00% | Add +16.6% | 1,377,584 | $2.1M |
| Deutsche Bank AG | 0.00% | Reduce -0.1% | 1,324,977 | $2.0M |
| Gsa Capital Partners LLP | 0.16% | Reduce -44.4% | 1,299,151 | $2.0M |
| Millennium Management | 0.00% | Reduce -22.7% | 1,185,879 | $1.8M |
| AlphaCentric Advisors LLC | 1.02% | No change | 1,125,000 | $1.7M |
| D. E. Shaw & Co. | 0.00% | Add +56.0% | 962,825 | $1.5M |
| Northern Trust Corp. | 0.00% | Reduce -3.8% | 958,805 | $1.4M |
| Renaissance Technologies | 0.00% | Reduce -53.8% | 906,800 | $1.4M |
| Barclays PLC | 0.00% | Reduce -8.0% | 892,815 | $1.3M |
| Altium Capital Management LLC | 0.50% | No change | 740,000 | $1.1M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Reduce -10.0% | 722,327 | $1.1M |
| Silverarc Capital Management, LLC | 0.24% | Reduce -0.6% | 558,466 | $843K |
| Macquarie Group Ltd. | 0.00% | Add +31.6% | 500,000 | $755K |
| Nuveen Asset Management, LLC | 0.00% | Add +8.4% | 492,365 | $743K |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.0% | 487,060 | $735K |
| Birchview Capital, LP | 0.58% | No change | 469,832 | $709K |
| Ikarian Capital, LLC | 0.17% | Add +2.3% | 409,355 | $618K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -1.0% | 387,520 | $585K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 309,909 | $468K |
| Morgan Stanley | 0.00% | Reduce -65.1% | 294,787 | $445K |
| FMR LLC | 0.00% | Add +2.1% | 273,808 | $413K |
| UBS Group AG | 0.00% | Reduce -44.2% | 254,933 | $385K |
| Atom Investors LP | 0.05% | Add +12.8% | 244,397 | $369K |
| XTX Topco Ltd | 0.05% | Add +394.4% | 242,841 | $367K |
| Panagora Asset Management Inc. | 0.00% | Add +1.1% | 229,924 | $347K |
| Exchange Traded Concepts, LLC | 0.01% | Add +83.5% | 212,638 | $321K |
| Alliancebernstein L.P. | 0.00% | No change | 192,810 | $291K |
| DAFNA Capital Management LLC | 0.07% | No change | 192,678 | $291K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -34.5% | 189,500 | $286K |
| Jane Street Group, LLC | 0.00% | Reduce -37.7% | 171,650 | $259K |
| Bank of America Corp. | 0.00% | Reduce -48.5% | 157,915 | $238K |
| Rhumbline Advisers | 0.00% | Add +4.3% | 144,028 | $217K |
| Royal Bank of Canada | 0.00% | Add +79.5% | 137,012 | $207K |
| Woodline Partners LP | 0.00% | Add +14.9% | 134,112 | $203K |
| AQR Capital Management | 0.00% | Reduce -79.0% | 125,826 | $190K |
| T. Rowe Price Associates Inc. | 0.00% | Add +9.2% | 95,091 | $144K |
| Boothbay Fund Management, LLC | 0.00% | Add +11.4% | 91,091 | $138K |
| Susquehanna International Group, LLP | 0.00% | Reduce -2.5% | 76,599 | $116K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +7.2% | 76,317 | $115K |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -8.2% | 27,015 | $105K |
| MetLife Investment Management, LLC | 0.00% | New | 60,551 | $91K |
| American International Group, Inc. | 0.00% | Reduce -0.8% | 55,816 | $84K |
| Simplex Trading, LLC | 0.00% | Add +166.6% | 55,985 | $84K |
| HSBC Holdings PLC | 0.00% | Add +18.3% | 53,563 | $81K |
| State of Wyoming | 0.01% | Add +66.4% | 47,307 | $71K |
| Bleakley Financial Group, LLC | 0.00% | Add +16.0% | 44,011 | $66K |
| Simplicity Wealth,LLC | 0.00% | New | 44,011 | $66K |
| Sei Investments Co. | 0.00% | New | 40,000 | $60K |
| Voya Investment Management LLC | 0.00% | Reduce -14.7% | 38,802 | $59K |
| Group One Trading LLC | 0.00% | Add +21.9% | 37,132 | $56K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 35,868 | $54K |
| Kennedy Investment Group, Inc. | 0.03% | No change | 35,000 | $53K |
| Wells Fargo & Company | 0.00% | Add +15.4% | 33,898 | $51K |
| Principal Financial Group Inc. | 0.00% | Add +5.5% | 33,165 | $50K |
| Focus Partners Wealth | 0.00% | New | 45,930 | $50K |
| ELCO Management Co., LLC | 0.03% | Add +41.4% | 31,901 | $48K |
| Freedom Investment Management, Inc. | 0.00% | New | 29,197 | $44K |
| Engineers Gate Manager LP | 0.00% | No change | 28,700 | $43K |
| Invesco Ltd. | 0.00% | Reduce -1.8% | 27,969 | $42K |
| Banque Cantonale Vaudoise | 0.00% | No change | 25,000 | $38K |
| Commonwealth Equity Services, LLC | 0.00% | New | 25,406 | $38K |
| Prelude Capital Management, LLC | 0.00% | New | 23,500 | $35K |
| New York State Common Retirement Fund | 0.00% | Add +9.2% | 21,150 | $32K |
| Baird Financial Group, Inc. | 0.00% | Add +50.7% | 20,800 | $31K |
| ProShare Advisors LLC | 0.00% | Add +8.6% | 20,348 | $31K |
| Prudential Financial Inc. | 0.00% | Reduce -21.0% | 19,615 | $30K |
| Citigroup Inc. | 0.00% | Add +15.2% | 18,924 | $29K |
| Diversified Trust Co. | 0.00% | No change | 18,580 | $28K |
| Winthrop Advisory Group LLC | 0.00% | New | 15,000 | $23K |
| Corient Private Wealth LP | 0.00% | Reduce -0.7% | 13,900 | $21K |
| Legal & General Group Plc | 0.00% | No change | 13,735 | $21K |
| Two Sigma Investments, LP | 0.00% | Reduce -90.4% | 13,691 | $21K |
| California State Teachers Retirement System | 0.00% | Reduce -38.9% | 11,387 | $17K |
| Snowden Capital Advisors LLC | 0.00% | No change | 11,000 | $17K |
| Two Sigma Securities, LLC | 0.00% | Reduce -47.9% | 10,208 | $15K |
| Janney Montgomery Scott LLC | 0.00% | No change | 10,000 | $15K |
| Osaic Holdings, Inc. | 0.00% | Add +33.4% | 8,595 | $13K |
| Metropolitan Life Insurance Co | 0.00% | New | 6,231 | $9K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 6,194 | $9K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 3,000 | $5K |
| Amalgamated Bank | 0.00% | Reduce -83.1% | 2,478 | $4K |
| Founders Capital Management | 0.00% | No change | 2,000 | $3K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -85.9% | 1,637 | $2K |
| Mb, Levis & Associates, LLC | 0.00% | No change | 1,500 | $2K |
| ADAR1 Capital Management, LLC | 0.00% | New | 1,479 | $2K |
| Harbour Investments, Inc. | 0.00% | No change | 1,300 | $2K |
| Headlands Technologies LLC | 0.00% | New | 1,242 | $2K |
"% of holder's portfolio" is KPTI's weight in each manager's 13F, not the share of Karyopharm Therapeutics Inc. the manager owns.