Karyopharm TherapeuticsKPTI
13F holders, Q2 2024 (June 30)114holders
26new positions
27sold out
5famous investors
$0.87avg. 13F price*
At the end of Q2 2024, 114 institutions reported holding Karyopharm Therapeutics Inc. (KPTI) in their 13F filings, unchanged from Q1 2024. 26 opened new positions and 27 sold out. The largest holders were Vanguard Group Inc. ($6.6M), Palo Alto Investors LP ($4.4M) and Eversept Partners, LP ($4.3M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Karyopharm Therapeutics Inc.
- CUSIP
- 48576U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024 → Q2 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $4.6M |
| Exits | 27 | $2.3M |
All 13F filers, Q1 2024 → Q2 2024: 11,612,389 shares bought and 18,888,753 shares sold, net −7,276,364 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 114 holders
| Vanguard Group Inc. | 0.00% | Reduce -8.2% | 7,654,482 | $6.6M |
| Palo Alto Investors LP | 0.51% | No change | 5,102,193 | $4.4M |
| Eversept Partners, LP | 0.33% | Reduce -0.6% | 4,987,180 | $4.3M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Add +23.4% | 4,319,842 | $3.7M |
| BlackRock Inc. | 0.00% | Reduce -55.9% | 4,169,788 | $3.6M |
| Citadel Advisors | 0.00% | Reduce -0.1% | 3,101,399 | $2.7M |
| Marshall Wace, LLP | 0.00% | Reduce -0.6% | 2,580,863 | $2.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +51.9% | 2,290,434 | $2.0M |
| BNP Paribas Financial Markets | 0.00% | Add +28.2% | 2,274,195 | $2.0M |
| Millennium Management | 0.00% | Add +76.5% | 2,092,426 | $1.8M |
| Avidity Partners Management LP | 0.07% | Reduce -75.7% | 2,018,500 | $1.8M |
| Jane Street Group, LLC | 0.00% | Add +803.0% | 1,549,976 | $1.3M |
| C WorldWide Group Holding A/S | 0.01% | No change | 1,500,000 | $1.3M |
| Opaleye Management Inc. | 0.29% | New | 1,425,000 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Reduce -48.0% | 1,311,536 | $1.1M |
| JPMorgan Chase & Co. | 0.00% | Reduce -7.4% | 1,275,859 | $1.1M |
| Deutsche Bank AG | 0.00% | Reduce -4.2% | 1,268,777 | $1.1M |
| Kennedy Capital Management LLC | 0.02% | New | 1,196,792 | $1.0M |
| AlphaCentric Advisors LLC | 0.72% | No change | 1,125,000 | $976K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Add +52.6% | 1,102,391 | $957K |
| Gsa Capital Partners LLP | 0.06% | Reduce -24.3% | 983,417 | $853K |
| Barclays PLC | 0.00% | Reduce -2.2% | 873,274 | $758K |
| Northern Trust Corp. | 0.00% | Reduce -9.2% | 870,167 | $755K |
| D. E. Shaw & Co. | 0.00% | Reduce -12.3% | 844,112 | $732K |
| Renaissance Technologies | 0.00% | Reduce -16.6% | 756,227 | $656K |
| AQR Capital Management | 0.00% | Add +494.5% | 748,020 | $649K |
| Altium Capital Management LLC | 0.27% | No change | 740,000 | $642K |
| Cubist Systematic Strategies, LLC | 0.01% | New | 568,975 | $494K |
| Silverarc Capital Management, LLC | 0.12% | No change | 558,466 | $485K |
| Superstring Capital Management LP | 0.58% | New | 534,485 | $464K |
| Macquarie Group Ltd. | 0.00% | Add +1.1% | 505,684 | $439K |
| Birchview Capital, LP | 0.38% | No change | 469,832 | $408K |
| State Street Corp. | 0.00% | Reduce -80.2% | 453,810 | $394K |
| Susquehanna International Group, LLP | 0.00% | Add +479.0% | 443,474 | $385K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 410,954 | $357K |
| Ikarian Capital, LLC | 0.11% | No change | 409,355 | $355K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -8.6% | 354,020 | $307K |
| Bank of America Corp. | 0.00% | Add +89.1% | 298,685 | $259K |
| FMR LLC | 0.00% | Add +7.1% | 293,213 | $254K |
| Bridgeway Capital Management, LLC | 0.01% | Add +39.6% | 264,500 | $229K |
| Atom Investors LP | 0.02% | Add +7.1% | 261,847 | $227K |
| Centiva Capital, LP | 0.01% | New | 203,600 | $177K |
| Morgan Stanley | 0.00% | Reduce -32.1% | 200,008 | $174K |
| DAFNA Capital Management LLC | 0.04% | No change | 192,678 | $167K |
| Acadian Asset Management LLC | 0.00% | New | 194,168 | $167K |
| Bank of New York Mellon Corp | 0.00% | Reduce -65.8% | 166,315 | $144K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.03% | New | 165,318 | $143K |
| Exchange Traded Concepts, LLC | 0.00% | Reduce -23.7% | 162,178 | $141K |
| Citigroup Inc. | 0.00% | Add +756.2% | 162,027 | $141K |
| HRT Financial LP | 0.00% | New | 147,536 | $128K |
| UBS Group AG | 0.00% | Reduce -44.8% | 140,678 | $122K |
| XTX Topco Ltd | 0.01% | Reduce -42.1% | 140,576 | $122K |
| Woodline Partners LP | 0.00% | No change | 134,112 | $116K |
| Qube Research & Technologies Ltd | 0.00% | New | 106,470 | $92K |
| T. Rowe Price Associates Inc. | 0.00% | Add +2.1% | 97,100 | $84K |
| Boothbay Fund Management, LLC | 0.00% | No change | 91,091 | $79K |
| State of Wyoming | 0.01% | Add +74.8% | 82,685 | $72K |
| Verition Fund Management LLC | 0.00% | New | 68,932 | $60K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 57,600 | $50K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | — | 56,945 | $49K |
| HSBC Holdings PLC | 0.00% | Reduce -0.9% | 53,091 | $48K |
| Royal Bank of Canada | 0.00% | Reduce -58.9% | 56,357 | $48K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -83.5% | 51,000 | $44K |
| Focus Partners Wealth | 0.00% | No change | 45,930 | $44K |
| Bleakley Financial Group, LLC | 0.00% | Add +11.7% | 49,160 | $43K |
| Simplicity Wealth,LLC | 0.00% | Add +11.7% | 49,160 | $43K |
| Invesco Ltd. | 0.00% | Add +44.8% | 40,511 | $35K |
| Sei Investments Co. | 0.00% | No change | 40,000 | $35K |
| Freedom Investment Management, Inc. | 0.00% | Add +31.3% | 38,326 | $33K |
| Baird Financial Group, Inc. | 0.00% | Add +76.9% | 36,800 | $32K |
| Point72 (DIFC) Ltd | 0.00% | New | 35,939 | $31K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +2049.3% | 35,184 | $31K |
| Kennedy Investment Group, Inc. | 0.02% | No change | 35,000 | $30K |
| Redwood Wealth Management Group, LLC | 0.02% | New | 34,030 | $30K |
| Engineers Gate Manager LP | 0.00% | No change | 28,700 | $25K |
| Catalyst Funds Management Pty Ltd | 0.01% | New | 28,600 | $25K |
| Jump Financial, LLC | 0.00% | New | 26,798 | $23K |
| Banque Cantonale Vaudoise | 0.00% | No change | 25,000 | $22K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -0.8% | 25,206 | $22K |
| Neuberger Berman Group LLC | 0.00% | New | 22,951 | $20K |
| Balyasny Asset Management L.P. | 0.00% | New | 22,562 | $20K |
| O'shaughnessy Asset Management, LLC | 0.00% | New | 21,941 | $19K |
| ELCO Management Co., LLC | 0.01% | Reduce -38.4% | 19,662 | $17K |
| Rhumbline Advisers | 0.00% | Reduce -88.6% | 16,431 | $14K |
| Paloma Partners Management Co | 0.00% | New | 15,435 | $13K |
| ProShare Advisors LLC | 0.00% | Reduce -25.4% | 15,170 | $13K |
| Winthrop Advisory Group LLC | 0.00% | No change | 15,000 | $13K |
| Victory Capital Management Inc. | 0.00% | New | 13,993 | $12K |
| Two Sigma Investments, LP | 0.00% | Add +1.3% | 13,866 | $12K |
| Corient Private Wealth LP | 0.00% | Reduce -2.2% | 13,600 | $12K |
| BLB&B Advisors, LLC | 0.00% | New | 11,150 | $10K |
| Snowden Capital Advisors LLC | 0.00% | No change | 11,000 | $10K |
| Scientech Research LLC | 0.00% | New | 10,950 | $10K |
| Janney Montgomery Scott LLC | 0.00% | No change | 10,000 | $9K |
| Osaic Holdings, Inc. | 0.00% | Reduce -16.1% | 7,213 | $6K |
| Cwm, LLC | 0.00% | Add +51966.7% | 6,248 | $5K |
| Quent Capital, LLC | 0.00% | New | 3,489 | $3K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 3,000 | $3K |
| Founders Capital Management | 0.00% | No change | 2,000 | $2K |
| Mb, Levis & Associates, LLC | 0.00% | No change | 1,500 | $1K |
"% of holder's portfolio" is KPTI's weight in each manager's 13F, not the share of Karyopharm Therapeutics Inc. the manager owns.