Kymera TherapeuticsKYMR
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 210 institutions reported holding Kymera Therapeutics Inc. (KYMR) in their 13F filings, unchanged from Q2 2025. 39 opened new positions and 37 sold out. The largest holders were Baker Bros. Advisors LP ($376.5M), Avoro Capital Advisors LLC ($359.4M) and FMR LLC ($332.8M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Kymera Therapeutics Inc.
- CUSIP
- 501575104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $142.0M |
| Exits | 37 | $82.0M |
All 13F filers, Q2 2025 → Q3 2025: 7,972,087 shares bought and 5,939,542 shares sold, net +2,032,545 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 210 holders
| Baker Bros. Advisors LP | 2.73% | No change | 6,651,429 | $376.5M |
| Avoro Capital Advisors LLC | 4.65% | Reduce -3.1% | 6,350,000 | $359.4M |
| FMR LLC | 0.02% | Add +8.2% | 5,879,611 | $332.8M |
| BVF Inc. | 12.63% | No change | 5,502,710 | $311.5M |
| Vanguard Group Inc. | 0.00% | Reduce -3.5% | 5,421,722 | $306.9M |
| Wellington Management Group LLP | 0.05% | Reduce -3.3% | 5,195,691 | $294.1M |
| T. Rowe Price Associates Inc. | 0.03% | Reduce -25.7% | 5,097,378 | $288.5M |
| Atlas Venture Life Science Advisors, LLC | 36.82% | No change | 4,896,462 | $277.1M |
| BlackRock, Inc. | 0.00% | Add +5.2% | 4,365,448 | $247.1M |
| Siren, L.L.C. | 7.59% | No change | 3,428,150 | $194.0M |
| State Street Corp. | 0.00% | Add +29.9% | 2,019,454 | $114.3M |
| Geode Capital Management, LLC | 0.00% | Add +7.0% | 1,276,766 | $72.3M |
| Capital Research Global Investors | 0.01% | No change | 1,262,182 | $71.4M |
| Jennison Associates LLC | 0.03% | Add +24.6% | 1,027,739 | $58.2M |
| Driehaus Capital Management LLC | 0.38% | Add +0.6% | 939,094 | $53.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +5.5% | 863,762 | $48.9M |
| Holocene Advisors, LP | 0.11% | New | 840,333 | $47.6M |
| Merck & Co., Inc. | 19.17% | No change | 772,165 | $43.7M |
| Commodore Capital LP | 2.07% | No change | 750,000 | $42.5M |
| Dimensional Fund Advisors LP | 0.01% | Add +29.8% | 731,420 | $41.4M |
| Goldman Sachs Group Inc. | 0.01% | Add +155.2% | 711,444 | $40.3M |
| UBS Group AG | 0.01% | Add +16.3% | 648,718 | $36.7M |
| Eventide Asset Management, LLC | 0.60% | Add +14.5% | 644,590 | $36.5M |
| Alyeska Investment Group, L.P. | 0.11% | Add +1130.2% | 615,091 | $34.8M |
| T. Rowe Price Investment Management, Inc. | 0.02% | Add +574.4% | 611,221 | $34.6M |
| Deerfield Management Company, L.P. | 0.54% | Reduce -12.4% | 572,258 | $32.4M |
| Federated Hermes, Inc. | 0.06% | New | 558,700 | $31.6M |
| Frontier Capital Management Co. LLC | 0.26% | Add +5.3% | 518,057 | $29.3M |
| AJU IB Investment Co., Ltd. | 22.47% | No change | 457,059 | $25.9M |
| Rock Springs Capital Management LP | 1.50% | No change | 450,374 | $25.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.5% | 439,825 | $24.9M |
| Northern Trust Corp. | 0.00% | Add +6.8% | 437,120 | $24.7M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -10.8% | 435,014 | $24.6M |
| Two Sigma Investments, LP | 0.04% | Add +170.2% | 429,975 | $24.3M |
| Polar Capital Holdings Plc | 0.11% | Add +58.8% | 397,041 | $22.5M |
| Morgan Stanley | 0.00% | Add +59.0% | 377,799 | $21.4M |
| Two Sigma Advisers, LP | 0.04% | Add +66.0% | 372,400 | $21.1M |
| Octagon Capital Advisors LP | 3.18% | Add +35.3% | 360,000 | $20.4M |
| Marshall Wace, LLP | 0.02% | Add +33.3% | 359,076 | $20.3M |
| Squarepoint Ops LLC | 0.04% | Add +954.0% | 351,246 | $19.9M |
| Pictet Asset Management Holding SA | 0.02% | Add +6140.0% | 346,817 | $19.8M |
| Nextech Invest Ltd. | 2.94% | No change | 340,909 | $19.3M |
| Deer Management Co. LLC | 1.65% | No change | 325,895 | $18.4M |
| Boxer Capital Management, LLC | 5.76% | Reduce -26.1% | 319,100 | $18.1M |
| First Turn Management, LLC | 2.36% | New | 277,726 | $15.7M |
| Braidwell LP | 0.63% | New | 276,692 | $15.7M |
| Logos Global Management LP | 1.40% | New | 250,000 | $14.2M |
| Woodline Partners LP | 0.07% | Reduce -50.2% | 248,000 | $14.0M |
| Gilder Gagnon Howe & Co. LLC | 0.14% | Reduce -25.0% | 246,704 | $14.0M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -21.8% | 238,000 | $13.5M |
| Royal Bank of Canada | 0.00% | Add +51.7% | 236,974 | $13.4M |
| TD Asset Management Inc | 0.01% | Reduce -10.9% | 209,248 | $11.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -7.2% | 192,699 | $10.9M |
| Candriam S.C.A. | 0.06% | Add +24.4% | 191,639 | $10.8M |
| Bank of America Corp. | 0.00% | Add +38.0% | 186,254 | $10.5M |
| Point72 Asset Management | 0.02% | Reduce -5.7% | 173,900 | $9.8M |
| Perceptive Advisors LLC | 0.28% | Reduce -19.2% | 169,796 | $9.6M |
| Barclays PLC | 0.00% | Add +8.4% | 155,144 | $8.8M |
| Bank of New York Mellon Corp | 0.00% | Add +16.6% | 152,452 | $8.6M |
| Foresite Capital Management VI LLC | 3.20% | No change | 146,332 | $8.3M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -16.9% | 126,490 | $7.2M |
| Yiheng Capital Management, L.P. | 2.30% | No change | 122,605 | $6.9M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +0.3% | 107,703 | $6.1M |
| Nuveen, LLC | 0.00% | Add +6.2% | 106,705 | $6.0M |
| Millennium Management | 0.00% | Add +68.0% | 94,961 | $5.4M |
| Patient Square Capital LP | 1.40% | Reduce -33.9% | 92,592 | $5.2M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 91,897 | $5.2M |
| Swiss National Bank | 0.00% | Add +9.7% | 81,600 | $4.6M |
| Atika Capital Management LLC | 0.39% | Reduce -44.5% | 81,300 | $4.6M |
| AXA Investment Managers S.A. | 0.01% | — | 80,534 | $4.6M |
| Invesco Ltd. | 0.00% | Add +66.7% | 79,807 | $4.5M |
| Burkehill Global Management, LP | 0.25% | No change | 75,000 | $4.2M |
| First Trust Advisors LP | 0.00% | New | 74,852 | $4.2M |
| Rhumbline Advisers | 0.00% | Add +4.4% | 74,173 | $4.2M |
| Trexquant Investment LP | 0.04% | Add +43.9% | 72,924 | $4.1M |
| Deutsche Bank AG | 0.00% | Add +42.9% | 72,737 | $4.1M |
| Rafferty Asset Management, LLC | 0.01% | Add +70.2% | 68,295 | $3.9M |
| Schroder Investment Management Group | 0.00% | Reduce -44.1% | 61,640 | $3.6M |
| Checkpoint Capital L.P. | 1.17% | Reduce -42.3% | 61,750 | $3.5M |
| Jain Global LLC | 0.05% | Add +51.1% | 58,480 | $3.3M |
| Informed Momentum Co LLC | 0.37% | New | 57,585 | $3.2M |
| Cubist Systematic Strategies, LLC | 0.04% | Reduce -55.6% | 52,754 | $3.0M |
| Nicholas Investment Partners, LP | 0.26% | New | 52,625 | $3.0M |
| Comerica Bank | 0.01% | Add +4.7% | 51,423 | $2.9M |
| Alliancebernstein L.P. | 0.00% | Add +3.7% | 48,769 | $2.8M |
| Legal & General Group Plc | 0.00% | Add +4.8% | 43,497 | $2.5M |
| Citadel Advisors | 0.00% | Reduce -91.9% | 41,823 | $2.4M |
| California State Teachers Retirement System | 0.00% | Add +12.1% | 40,699 | $2.3M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -32.5% | 39,746 | $2.2M |
| Voya Investment Management LLC | 0.00% | Add +22.4% | 36,455 | $2.1M |
| Wells Fargo & Company | 0.00% | Add +25.4% | 32,061 | $1.8M |
| Franklin Resources Inc. | 0.00% | Reduce -5.9% | 31,662 | $1.8M |
| Verition Fund Management LLC | 0.01% | Add +270.9% | 31,471 | $1.8M |
| Victory Capital Management Inc. | 0.00% | Add +5.6% | 31,289 | $1.8M |
| Dark Forest Capital Management LP | 0.07% | Add +19.7% | 31,052 | $1.8M |
| Nan Fung Group Holdings Ltd | 2.93% | No change | 30,875 | $1.7M |
| Harbor Capital Advisors, Inc. | 0.13% | Reduce -10.6% | 29,928 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Add +6.2% | 29,499 | $1.7M |
| Moody Aldrich Partners LLC | 0.31% | Reduce -16.9% | 28,910 | $1.6M |
| Erste Asset Management GmbH | 0.02% | No change | 27,000 | $1.6M |
| State of Wisconsin Investment Board | 0.00% | Reduce -15.3% | 27,772 | $1.6M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -2.5% | 26,918 | $1.5M |
| New York State Common Retirement Fund | 0.00% | Add +67.7% | 24,396 | $1.4M |
| Ameriprise Financial Inc. | 0.00% | Add +23.2% | 24,058 | $1.4M |
| Hudson Bay Capital Management LP | 0.01% | Add +362.7% | 23,134 | $1.3M |
| China Universal Asset Management Co., Ltd. | 0.11% | Reduce -2.4% | 22,532 | $1.3M |
| Handelsbanken Fonder AB | 0.00% | Add +31.5% | 21,700 | $1.2M |
| Neo Ivy Capital Management | 0.27% | Reduce -4.1% | 19,660 | $1.1M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -28.9% | 18,991 | $1.1M |
| Knights of Columbus Asset Advisors LLC | 0.06% | New | 18,891 | $1.1M |
| Janus Henderson Group PLC | 0.00% | Reduce -5.2% | 18,308 | $1.0M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 17,907 | $1.0M |
| HighVista Strategies LLC | 0.22% | New | 15,728 | $890K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 23,562 | $869K |
| Aquatic Capital Management LLC | 0.02% | Reduce -9.8% | 15,353 | $869K |
| Sei Investments Co. | 0.00% | Add +151.0% | 15,246 | $863K |
| Profund Advisors LLC | 0.03% | Add +70.0% | 15,013 | $850K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +11.9% | 14,842 | $840K |
| Intech Investment Management LLC | 0.01% | Reduce -36.0% | 14,711 | $833K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +33.9% | 13,938 | $789K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Add +143.9% | 13,768 | $779K |
| Arizona State Retirement System | 0.00% | Add +9.5% | 12,431 | $704K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 12,245 | $693K |
| Aigen Investment Management, LP | 0.10% | New | 11,877 | $672K |
| ProShare Advisors LLC | 0.00% | Reduce -7.2% | 11,169 | $632K |
| Westwood Holdings Group Inc. | 0.00% | New | 10,926 | $618K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 10,491 | $614K |
| Susquehanna International Group, LLP | 0.00% | Reduce -81.3% | 10,748 | $608K |
| BNP Paribas Financial Markets | 0.00% | Add +113.7% | 10,647 | $603K |
| HSBC Holdings PLC | 0.00% | Add +43.4% | 10,314 | $593K |
| Teacher Retirement System of Texas | 0.00% | Reduce -1.8% | 10,314 | $584K |
| Kennedy Capital Management LLC | 0.01% | Add +96.1% | 9,482 | $537K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.5% | 9,074 | $514K |
| KLP Kapitalforvaltning As | 0.00% | Add +16.9% | 9,000 | $509K |
| AQR Capital Management | 0.00% | Add +6.6% | 8,620 | $488K |
| SG Americas Securities, LLC | 0.00% | Reduce -61.8% | 8,432 | $477K |
| Perbak Capital Partners LLP | 0.07% | New | 7,504 | $425K |
| Vident Advisory, LLC | 0.00% | Reduce -17.3% | 7,116 | $403K |
| Proficio Capital Partners LLC | 0.03% | No change | 7,000 | $396K |
| Baron Capital (BAMCO) | 0.00% | New | 7,000 | $396K |
| Citigroup Inc. | 0.00% | Reduce -75.9% | 6,906 | $391K |
| Legato Capital Management LLC | 0.04% | New | 6,783 | $384K |
| Prudential Financial Inc. | 0.00% | Reduce -89.8% | 6,550 | $371K |
| Engineers Gate Manager LP | 0.00% | New | 6,475 | $366K |
| AlphaQuest LLC | 0.02% | Add +19.4% | 6,078 | $344K |
| Bryce Point Capital, LLC | 0.41% | New | 5,921 | $335K |
| CIBC Bancorp USA Inc. | 0.00% | — | 5,375 | $304K |
| Altfest L J & Co. Inc. | 0.03% | New | 5,318 | $301K |
| Gsa Capital Partners LLP | 0.02% | New | 5,137 | $291K |
| Creative Planning | 0.00% | New | 5,027 | $285K |
| Advisors Asset Management, Inc. | 0.00% | Reduce -0.4% | 4,943 | $280K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 4,672 | $264K |
| Campbell & CO Investment Adviser LLC | 0.02% | New | 4,571 | $259K |
| Glenmede Investment Management, LP | 0.00% | Reduce -14.9% | 4,241 | $240K |
| Ameritas Investment Partners, Inc. | 0.01% | Reduce -14.2% | 4,213 | $238K |
| Xponance LLC | 0.00% | New | 3,983 | $225K |
| Principal Financial Group Inc. | 0.00% | New | 3,858 | $218K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +9.9% | 2,764 | $156K |
| Virtus Investment Advisers, LLC | 0.04% | Add +21.0% | 2,406 | $136K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -59.6% | 2,193 | $124K |
| US Bancorp \de | 0.00% | Add +9.8% | 1,865 | $106K |
| KBC Group NV | 0.00% | No change | 1,716 | $97K |
| Shell Asset Management Co. | 0.01% | Reduce -56.3% | 1,670 | $95K |
| Amalgamated Bank | 0.00% | No change | 1,626 | $92K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -7.2% | 1,538 | $87K |
| Osaic Holdings, Inc. | 0.00% | Add +20.3% | 1,310 | $76K |
| Bessemer Group Inc. | 0.00% | Add +652.0% | 940 | $53K |
| MAI Capital Management | 0.00% | No change | 924 | $52K |
| Point72 Europe (London) LLP | 0.00% | New | 796 | $45K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -14.5% | 788 | $45K |
| Larson Financial Group LLC | 0.00% | Add +81.5% | 777 | $44K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -1.0% | 499 | $28K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +20.1% | 412 | $23K |
| Arax Advisory Partners | 0.00% | New | 358 | $20K |
| Optiver Holding B.V. | 0.00% | New | 322 | $18K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -0.7% | 286 | $16K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +3.3% | 284 | $16K |
| Truvestments Capital LLC | 0.00% | Reduce -13.8% | 274 | $16K |
| Cwm, LLC | 0.00% | Add +8.8% | 259 | $15K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -12.2% | 215 | $12K |
| Jones Financial Companies LLLP | 0.00% | Add +122.0% | 202 | $11K |
| Whittier Trust Co. | 0.00% | New | 183 | $11K |
| IFP Advisors, Inc | 0.00% | Add +168.1% | 185 | $10K |
| GAMMA Investing LLC | 0.00% | Reduce -8.1% | 171 | $10K |
| Signaturefd, LLC | 0.00% | No change | 140 | $8K |
| Sterling Capital Management LLC | 0.00% | Add +7.0% | 122 | $7K |
| Rockefeller Capital Management L.P. | 0.00% | New | 118 | $7K |
| Smartleaf Asset Management LLC | 0.00% | Add +98.2% | 111 | $6K |
| Rothschild Investment LLC | 0.00% | Reduce -17.4% | 95 | $5K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -86.5% | 84 | $5K |
| Parkside Financial Bank & Trust | 0.00% | Add +21.4% | 68 | $4K |
| Allworth Financial LP | 0.00% | Add +15.8% | 44 | $2K |
| Root Financial Partners, LLC | 0.00% | New | 40 | $2K |
| Bare Financial Services, Inc | 0.00% | No change | 21 | $1K |
| Parallel Advisors, LLC | 0.00% | No change | 20 | $1K |
| Fortitude Family Office, LLC | 0.00% | No change | 18 | $1K |
| Advisory Services Network, LLC | 0.00% | New | 13 | $736 |
| TD Private Client Wealth LLC | 0.00% | New | 12 | $679 |
| Montag A & Associates Inc. | 0.00% | New | 6 | $340 |
| Assetmark, Inc. | 0.00% | No change | 6 | $340 |
| Principal Securities, Inc. | 0.00% | No change | 5 | $283 |
| Wealthspire Advisors, LLC | 0.00% | New | 5 | $283 |
| DiNuzzo Private Wealth, Inc. | 0.00% | New | 2 | $83 |
| JFS Wealth Advisors, LLC | 0.00% | New | 1 | $57 |
| SJS Investment Consulting Inc. | 0.00% | No change | 1 | $57 |
| Rialto Wealth Management, LLC | 0.00% | No change | 1 | $57 |
| HFM Investment Advisors, LLC | 0.00% | New | 1 | $57 |
| Hemington Wealth Management | 0.00% | New | 6 | $0 |
| Covestor Ltd | 0.00% | No change | 4 | $0 |
| Cloud Capital Management, LLC | 0.00% | New | 2 | $0 |
"% of holder's portfolio" is KYMR's weight in each manager's 13F, not the share of Kymera Therapeutics Inc. the manager owns.