Mirum PharmaceuticalsMIRM
13F holders, Q4 2025 (December 31)283holders +11
47new positions
41sold out
8famous investors
$78.99avg. 13F price*
At the end of Q4 2025, 283 institutions reported holding Mirum Pharmaceuticals Inc. (MIRM) in their 13F filings, up 11 from Q3 2025. 47 opened new positions and 41 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($536.7M), Janus Henderson Group PLC ($479.1M) and BlackRock, Inc. ($287.9M). 8 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Mirum Pharmaceuticals Inc.
- CUSIP
- 604749101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 47 | $152.4M |
| Exits | 41 | $90.8M |
All 13F filers, Q3 2025 → Q4 2025: 7,722,971 shares bought and 4,364,887 shares sold, net +3,358,084 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 283 holders
| Frazier Life Sciences Management, L.P. | 14.46% | No change | 6,795,121 | $536.7M |
| Janus Henderson Group PLC | 0.21% | Add +21.4% | 6,065,308 | $479.1M |
| BlackRock, Inc. | 0.00% | Add +1.2% | 3,645,286 | $287.9M |
| Vanguard Group Inc. | 0.00% | Add +2.0% | 2,596,089 | $205.1M |
| State Street Corp. | 0.01% | Add +59.2% | 2,143,992 | $169.4M |
| Eventide Asset Management, LLC | 2.58% | Reduce -17.0% | 2,093,582 | $165.4M |
| BVF Inc. | 3.98% | No change | 1,495,290 | $118.1M |
| T. Rowe Price Associates Inc. | 0.01% | Add +10.7% | 1,420,375 | $112.2M |
| Novo Holdings A/S | 7.75% | No change | 1,264,028 | $99.8M |
| Wellington Management Group LLP | 0.02% | Add +56.5% | 1,237,830 | $97.8M |
| Tang Capital Management LLC | 4.82% | No change | 1,236,027 | $97.6M |
| Geode Capital Management, LLC | 0.01% | Add +5.2% | 1,062,926 | $84.0M |
| D. E. Shaw & Co. | 0.06% | Add +2.7% | 948,161 | $74.9M |
| Clearbridge Investments, LLC | 0.05% | Reduce -13.7% | 865,967 | $68.4M |
| Citadel Advisors | 0.05% | Reduce -19.3% | 840,220 | $66.4M |
| Polar Capital Holdings Plc | 0.29% | Reduce -3.3% | 793,642 | $62.7M |
| Rock Springs Capital Management LP | 3.10% | Add +0.1% | 762,294 | $60.2M |
| Goldman Sachs Group Inc. | 0.01% | Add +60.7% | 724,317 | $57.2M |
| Bank of America Corp. | 0.00% | Add +82.7% | 713,452 | $56.4M |
| BNP Paribas Financial Markets | 0.03% | Add +9.1% | 655,778 | $51.8M |
| Franklin Resources Inc. | 0.01% | Add +8.3% | 650,715 | $51.4M |
| FMR LLC | 0.00% | Add +1.0% | 646,466 | $51.1M |
| Lord, Abbett & Co. LLC | 0.15% | Reduce -12.4% | 579,983 | $45.8M |
| Pictet Asset Management Holding SA | 0.04% | Add +6.7% | 577,274 | $45.6M |
| Soleus Capital Management, L.P. | 1.92% | Add +285.8% | 573,614 | $45.3M |
| Candriam S.C.A. | 0.23% | Add +41.3% | 569,590 | $45.0M |
| Woodline Partners LP | 0.17% | No change | 567,894 | $44.9M |
| Bank of New York Mellon Corp | 0.01% | Add +26.9% | 565,579 | $44.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.11% | Add +5.2% | 521,652 | $41.2M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -4.5% | 514,981 | $40.7M |
| Nuveen, LLC | 0.01% | Reduce -16.4% | 503,045 | $39.7M |
| Federated Hermes, Inc. | 0.06% | Add +39.1% | 481,961 | $38.1M |
| First Turn Management, LLC | 4.35% | Reduce -15.6% | 481,564 | $38.0M |
| Adage Capital Partners Gp, L.L.C. | 0.06% | Reduce -6.0% | 467,468 | $36.9M |
| Renaissance Technologies | 0.05% | Reduce -14.5% | 439,085 | $34.7M |
| Morgan Stanley | 0.00% | Reduce -36.5% | 425,685 | $33.6M |
| Nomura Asset Management International Inc. | 0.05% | — | 421,845 | $33.3M |
| Boone Capital Management LLC | 10.44% | Reduce -21.4% | 421,236 | $33.3M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.8% | 409,286 | $32.3M |
| TimesSquare Capital Management, LLC | 0.47% | Add +31.7% | 395,827 | $31.3M |
| Two Sigma Investments, LP | 0.05% | Add +13.2% | 388,542 | $30.7M |
| Northern Trust Corp. | 0.00% | Reduce -2.7% | 374,864 | $29.6M |
| Arrowstreet Capital, Limited Partnership | 0.02% | Reduce -39.2% | 372,511 | $29.4M |
| Next Century Growth Investors LLC | 2.02% | Add +2.0% | 368,035 | $29.1M |
| Emerald Advisers, LLC | 0.89% | Reduce -0.7% | 367,134 | $29.0M |
| William Blair Investment Management, LLC | 0.07% | Add +7.5% | 336,701 | $26.6M |
| UBS Group AG | 0.01% | Add +16.3% | 320,783 | $25.3M |
| Patient Square Capital LP | 5.05% | Add +186.5% | 298,682 | $23.6M |
| Voloridge Investment Management, LLC | 0.08% | Reduce -23.5% | 297,950 | $23.5M |
| Balyasny Asset Management L.P. | 0.04% | Reduce -9.9% | 285,870 | $22.6M |
| Penn Capital Management Company, LLC | 1.78% | Reduce -8.5% | 281,918 | $22.3M |
| Hood River Capital Management LLC | 0.24% | New | 280,028 | $22.1M |
| Ameriprise Financial Inc. | 0.00% | Add +33.7% | 271,480 | $21.4M |
| Norges Bank | 0.00% | — | 263,175 | $20.8M |
| Perceptive Advisors LLC | 0.38% | New | 259,545 | $20.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.02% | New | 257,228 | $20.3M |
| Erste Asset Management GmbH | 0.17% | No change | 250,000 | $19.8M |
| Raymond James Financial Inc. | 0.01% | Reduce -2.1% | 246,418 | $19.5M |
| Millennium Management | 0.01% | Reduce -21.0% | 244,273 | $19.3M |
| Emerald Mutual Fund Advisers Trust | 0.93% | Add +10.6% | 242,320 | $19.1M |
| Two Sigma Advisers, LP | 0.04% | Reduce -16.0% | 232,100 | $18.3M |
| Nan Fung Trinity (hk) Ltd. | 1.42% | Add +45.6% | 227,479 | $18.0M |
| Logos Global Management LP | 1.18% | New | 225,000 | $17.8M |
| New York State Common Retirement Fund | 0.02% | Reduce -10.6% | 217,606 | $17.2M |
| Handelsbanken Fonder AB | 0.05% | New | 213,500 | $16.9M |
| Nicholas Investment Partners, LP | 1.39% | Reduce -1.7% | 213,391 | $16.9M |
| Russell Investments Group, Ltd. | 0.02% | Reduce -25.0% | 209,174 | $16.5M |
| Point72 Asset Management | 0.02% | Reduce -75.9% | 190,638 | $15.1M |
| Deutsche Bank AG | 0.00% | Add +1.3% | 186,712 | $14.7M |
| Segall Bryant & Hamill, LLC | 0.20% | New | 185,024 | $14.6M |
| Algert Global LLC | 0.21% | Reduce -8.6% | 174,189 | $13.8M |
| Voleon Capital Management LP | 0.29% | Add +100.0% | 173,067 | $13.7M |
| Squarepoint Ops LLC | 0.03% | Add +34.8% | 172,426 | $13.6M |
| Legal & General Group Plc | 0.00% | Add +0.7% | 168,393 | $13.3M |
| Rice Hall James & Associates, LLC | 0.72% | Reduce -0.2% | 164,449 | $13.0M |
| Palo Alto Investors LP | 1.72% | Add +141.8% | 156,421 | $12.4M |
| Citigroup Inc. | 0.01% | Reduce -0.9% | 145,992 | $11.5M |
| PDT Partners, LLC | 0.74% | No change | 145,379 | $11.5M |
| Barclays PLC | 0.00% | Add +22.8% | 142,144 | $11.2M |
| First Trust Advisors LP | 0.01% | Reduce -4.5% | 137,700 | $10.9M |
| Ensign Peak Advisors, Inc | 0.02% | No change | 133,973 | $10.6M |
| Highlander Partners, L.P. | 3.49% | No change | 122,980 | $9.7M |
| Wells Fargo & Company | 0.00% | Add +326.5% | 115,437 | $9.1M |
| Essex Investment Management Co. LLC | 1.34% | Reduce -1.9% | 111,310 | $8.8M |
| Qube Research & Technologies Ltd | 0.01% | Add +141.9% | 109,001 | $8.6M |
| Rhenman & Partners Asset Management AB | 0.78% | Add +88.9% | 106,255 | $8.4M |
| Marshall Wace, LLP | 0.01% | Add +157.8% | 102,703 | $8.1M |
| Hennion & Walsh Asset Management, Inc. | 0.27% | Reduce -15.2% | 98,294 | $7.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -2.8% | 97,386 | $7.7M |
| Silvercrest Asset Management Group LLC | 0.05% | No change | 90,056 | $7.1M |
| Atle Fund Management AB | 2.26% | Reduce -4.2% | 89,685 | $7.1M |
| Swiss National Bank | 0.00% | Add +3.2% | 74,300 | $5.9M |
| Rafferty Asset Management, LLC | 0.02% | Add +120.2% | 72,943 | $5.8M |
| Victory Capital Management Inc. | 0.00% | Add +445.1% | 72,194 | $5.7M |
| Voya Investment Management LLC | 0.01% | Reduce -14.1% | 67,749 | $5.4M |
| Vestal Point Capital, LP | 0.19% | New | 66,000 | $5.2M |
| Invesco Ltd. | 0.00% | Reduce -36.0% | 64,951 | $5.1M |
| Capital Fund Management S.A. | 0.05% | Add +72.5% | 62,313 | $4.9M |
| TCG Crossover Management, LLC | 0.16% | New | 62,049 | $4.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -2.5% | 59,201 | $4.7M |
"% of holder's portfolio" is MIRM's weight in each manager's 13F, not the share of Mirum Pharmaceuticals Inc. the manager owns.