Mirum PharmaceuticalsMIRM

13F holders, Q4 2025 (December 31)
283holders +11
47new positions
41sold out
8famous investors
$78.99avg. 13F price*

At the end of Q4 2025, 283 institutions reported holding Mirum Pharmaceuticals Inc. (MIRM) in their 13F filings, up 11 from Q3 2025. 47 opened new positions and 41 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($536.7M), Janus Henderson Group PLC ($479.1M) and BlackRock, Inc. ($287.9M). 8 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Mirum Pharmaceuticals Inc.
CUSIP
604749101
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 172Q1 2024Q2 2024: 161Q2 2024Q3 2024: 178Q3 2024Q4 2024: 205Q4 2024Q1 2025: 214Q1 2025Q2 2025: 214Q2 2025Q3 2025: 272Q3 2025Q4 2025: 283Q4 2025Q1 2026: 311Q1 2026Q2 2026: 326Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions47$152.4M
Exits41$90.8M

All 13F filers, Q3 2025 → Q4 2025: 7,722,971 shares bought and 4,364,887 shares sold, net +3,358,084 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 283 holders

Frazier Life Sciences Management, L.P. 14.46% No change 6,795,121 $536.7M
Janus Henderson Group PLC 0.21% Add +21.4% 6,065,308 $479.1M
BlackRock, Inc. 0.00% Add +1.2% 3,645,286 $287.9M
Vanguard Group Inc. 0.00% Add +2.0% 2,596,089 $205.1M
State Street Corp. 0.01% Add +59.2% 2,143,992 $169.4M
Eventide Asset Management, LLC 2.58% Reduce -17.0% 2,093,582 $165.4M
BVF Inc. 3.98% No change 1,495,290 $118.1M
T. Rowe Price Associates Inc. 0.01% Add +10.7% 1,420,375 $112.2M
Novo Holdings A/S 7.75% No change 1,264,028 $99.8M
Wellington Management Group LLP 0.02% Add +56.5% 1,237,830 $97.8M
Tang Capital Management LLC 4.82% No change 1,236,027 $97.6M
Geode Capital Management, LLC 0.01% Add +5.2% 1,062,926 $84.0M
D. E. Shaw & Co. 0.06% Add +2.7% 948,161 $74.9M
Clearbridge Investments, LLC 0.05% Reduce -13.7% 865,967 $68.4M
Citadel Advisors 0.05% Reduce -19.3% 840,220 $66.4M
Polar Capital Holdings Plc 0.29% Reduce -3.3% 793,642 $62.7M
Rock Springs Capital Management LP 3.10% Add +0.1% 762,294 $60.2M
Goldman Sachs Group Inc. 0.01% Add +60.7% 724,317 $57.2M
Bank of America Corp. 0.00% Add +82.7% 713,452 $56.4M
BNP Paribas Financial Markets 0.03% Add +9.1% 655,778 $51.8M
Franklin Resources Inc. 0.01% Add +8.3% 650,715 $51.4M
FMR LLC 0.00% Add +1.0% 646,466 $51.1M
Lord, Abbett & Co. LLC 0.15% Reduce -12.4% 579,983 $45.8M
Pictet Asset Management Holding SA 0.04% Add +6.7% 577,274 $45.6M
Soleus Capital Management, L.P. 1.92% Add +285.8% 573,614 $45.3M
Candriam S.C.A. 0.23% Add +41.3% 569,590 $45.0M
Woodline Partners LP 0.17% No change 567,894 $44.9M
Bank of New York Mellon Corp 0.01% Add +26.9% 565,579 $44.7M
Connor, Clark & Lunn Investment Management Ltd. 0.11% Add +5.2% 521,652 $41.2M
Loomis Sayles & Co. L P 0.05% Reduce -4.5% 514,981 $40.7M
Nuveen, LLC 0.01% Reduce -16.4% 503,045 $39.7M
Federated Hermes, Inc. 0.06% Add +39.1% 481,961 $38.1M
First Turn Management, LLC 4.35% Reduce -15.6% 481,564 $38.0M
Adage Capital Partners Gp, L.L.C. 0.06% Reduce -6.0% 467,468 $36.9M
Renaissance Technologies 0.05% Reduce -14.5% 439,085 $34.7M
Morgan Stanley 0.00% Reduce -36.5% 425,685 $33.6M
Nomura Asset Management International Inc. 0.05% — 421,845 $33.3M
Boone Capital Management LLC 10.44% Reduce -21.4% 421,236 $33.3M
Charles Schwab Investment Management Inc. 0.01% Add +3.8% 409,286 $32.3M
TimesSquare Capital Management, LLC 0.47% Add +31.7% 395,827 $31.3M
Two Sigma Investments, LP 0.05% Add +13.2% 388,542 $30.7M
Northern Trust Corp. 0.00% Reduce -2.7% 374,864 $29.6M
Arrowstreet Capital, Limited Partnership 0.02% Reduce -39.2% 372,511 $29.4M
Next Century Growth Investors LLC 2.02% Add +2.0% 368,035 $29.1M
Emerald Advisers, LLC 0.89% Reduce -0.7% 367,134 $29.0M
William Blair Investment Management, LLC 0.07% Add +7.5% 336,701 $26.6M
UBS Group AG 0.01% Add +16.3% 320,783 $25.3M
Patient Square Capital LP 5.05% Add +186.5% 298,682 $23.6M
Voloridge Investment Management, LLC 0.08% Reduce -23.5% 297,950 $23.5M
Balyasny Asset Management L.P. 0.04% Reduce -9.9% 285,870 $22.6M
Penn Capital Management Company, LLC 1.78% Reduce -8.5% 281,918 $22.3M
Hood River Capital Management LLC 0.24% New 280,028 $22.1M
Ameriprise Financial Inc. 0.00% Add +33.7% 271,480 $21.4M
Norges Bank 0.00% — 263,175 $20.8M
Perceptive Advisors LLC 0.38% New 259,545 $20.5M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.02% New 257,228 $20.3M
Erste Asset Management GmbH 0.17% No change 250,000 $19.8M
Raymond James Financial Inc. 0.01% Reduce -2.1% 246,418 $19.5M
Millennium Management 0.01% Reduce -21.0% 244,273 $19.3M
Emerald Mutual Fund Advisers Trust 0.93% Add +10.6% 242,320 $19.1M
Two Sigma Advisers, LP 0.04% Reduce -16.0% 232,100 $18.3M
Nan Fung Trinity (hk) Ltd. 1.42% Add +45.6% 227,479 $18.0M
Logos Global Management LP 1.18% New 225,000 $17.8M
New York State Common Retirement Fund 0.02% Reduce -10.6% 217,606 $17.2M
Handelsbanken Fonder AB 0.05% New 213,500 $16.9M
Nicholas Investment Partners, LP 1.39% Reduce -1.7% 213,391 $16.9M
Russell Investments Group, Ltd. 0.02% Reduce -25.0% 209,174 $16.5M
Point72 Asset Management 0.02% Reduce -75.9% 190,638 $15.1M
Deutsche Bank AG 0.00% Add +1.3% 186,712 $14.7M
Segall Bryant & Hamill, LLC 0.20% New 185,024 $14.6M
Algert Global LLC 0.21% Reduce -8.6% 174,189 $13.8M
Voleon Capital Management LP 0.29% Add +100.0% 173,067 $13.7M
Squarepoint Ops LLC 0.03% Add +34.8% 172,426 $13.6M
Legal & General Group Plc 0.00% Add +0.7% 168,393 $13.3M
Rice Hall James & Associates, LLC 0.72% Reduce -0.2% 164,449 $13.0M
Palo Alto Investors LP 1.72% Add +141.8% 156,421 $12.4M
Citigroup Inc. 0.01% Reduce -0.9% 145,992 $11.5M
PDT Partners, LLC 0.74% No change 145,379 $11.5M
Barclays PLC 0.00% Add +22.8% 142,144 $11.2M
First Trust Advisors LP 0.01% Reduce -4.5% 137,700 $10.9M
Ensign Peak Advisors, Inc 0.02% No change 133,973 $10.6M
Highlander Partners, L.P. 3.49% No change 122,980 $9.7M
Wells Fargo & Company 0.00% Add +326.5% 115,437 $9.1M
Essex Investment Management Co. LLC 1.34% Reduce -1.9% 111,310 $8.8M
Qube Research & Technologies Ltd 0.01% Add +141.9% 109,001 $8.6M
Rhenman & Partners Asset Management AB 0.78% Add +88.9% 106,255 $8.4M
Marshall Wace, LLP 0.01% Add +157.8% 102,703 $8.1M
Hennion & Walsh Asset Management, Inc. 0.27% Reduce -15.2% 98,294 $7.8M
JPMorgan Chase & Co. 0.00% Reduce -2.8% 97,386 $7.7M
Silvercrest Asset Management Group LLC 0.05% No change 90,056 $7.1M
Atle Fund Management AB 2.26% Reduce -4.2% 89,685 $7.1M
Swiss National Bank 0.00% Add +3.2% 74,300 $5.9M
Rafferty Asset Management, LLC 0.02% Add +120.2% 72,943 $5.8M
Victory Capital Management Inc. 0.00% Add +445.1% 72,194 $5.7M
Voya Investment Management LLC 0.01% Reduce -14.1% 67,749 $5.4M
Vestal Point Capital, LP 0.19% New 66,000 $5.2M
Invesco Ltd. 0.00% Reduce -36.0% 64,951 $5.1M
Capital Fund Management S.A. 0.05% Add +72.5% 62,313 $4.9M
TCG Crossover Management, LLC 0.16% New 62,049 $4.9M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -2.5% 59,201 $4.7M
Bank of Montreal 0.00% Add +0.1% 57,069 $4.5M
Jump Financial, LLC 0.06% Reduce -67.1% 53,265 $4.2M
F/m Investments LLC 0.16% Add +78.1% 53,088 $4.2M
Rhumbline Advisers 0.00% Reduce -14.0% 50,774 $4.0M
Secure Asset Management, LLC 0.63% Add +4.0% 50,384 $4.0M
Prudential Financial Inc. 0.00% Reduce -7.5% 50,100 $4.0M
Informed Momentum Co LLC 0.42% Reduce -23.8% 48,066 $3.8M
Hillsdale Investment Management Inc. 0.10% New 47,630 $3.8M
State of Wisconsin Investment Board 0.01% Reduce -28.9% 46,206 $3.6M
Sei Investments Co. 0.00% Add +195.3% 46,078 $3.6M
CenterBook Partners LP 0.18% Add +442.9% 45,367 $3.6M
Legato Capital Management LLC 0.30% Add +27.6% 44,124 $3.5M
Alliancebernstein L.P. 0.00% No change 43,450 $3.4M
Alps Advisors Inc. 0.02% Add +75.2% 42,097 $3.3M
Thrivent Financial for Lutherans 0.01% New 41,857 $3.3M
XTX Topco Ltd 0.08% New 40,249 $3.2M
California State Teachers Retirement System 0.00% Add +9.9% 36,411 $2.9M
Manufacturers Life Insurance Company, The 0.00% Add +19.7% 34,114 $2.7M
Canada Pension Plan Investment Board 0.00% Add +62.8% 33,696 $2.7M
AQR Capital Management 0.00% Add +3.5% 32,485 $2.6M
Trails Edge Capital Partners, LP 0.62% — 31,862 $2.5M
Principal Financial Group Inc. 0.00% Add +41.1% 31,659 $2.5M
Creative Planning 0.00% Add +147.3% 31,519 $2.5M
Zacks Investment Management 0.02% New 30,398 $2.4M
Allianz Asset Management GmbH 0.00% Add +880.1% 27,444 $2.2M
Faithward Advisors, LLC 0.32% New 27,341 $2.2M
Profund Advisors LLC 0.07% Add +257.6% 27,091 $2.1M
Los Angeles Capital Management LLC 0.01% Add +7.6% 27,896 $2.0M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +267.0% 24,126 $1.9M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +13.9% 23,292 $1.8M
TD Asset Management Inc 0.00% Add +51.1% 23,276 $1.8M
Sofinnova Investments, Inc. 0.08% New 23,100 $1.8M
MetLife Investment Management, LLC 0.01% Reduce -3.1% 22,739 $1.8M
Pathstone Holdings, LLC 0.01% New 21,676 $1.7M
Envestnet Asset Management Inc. 0.00% Add +201.2% 20,486 $1.6M
Royal Bank of Canada 0.00% Add +32.2% 20,172 $1.6M
Penserra Capital Management LLC 0.02% Reduce -24.0% 20,128 $1.6M
Mackenzie Financial Corp. 0.00% Add +425.2% 19,889 $1.6M
Knights of Columbus Asset Advisors LLC 0.09% Reduce -3.1% 19,499 $1.5M
Ascentis Independent Advisors 0.25% No change 19,380 $1.5M
SG Americas Securities, LLC 0.00% New 18,710 $1.5M
Martingale Asset Management L P 0.04% New 18,226 $1.4M
Teachers Retirement System of the State of Kentucky 0.01% Add +18.1% 17,382 $1.4M
Oak Ridge Investments LLC 0.08% Reduce -2.6% 17,289 $1.4M
Intech Investment Management LLC 0.01% No change 17,188 $1.4M
Values First Advisors, Inc. 0.67% Reduce -12.2% 16,424 $1.3M
SBI Okasan Asset Management Co.Ltd. 0.07% — 16,000 $1.3M
Commonwealth Equity Services, LLC 0.00% Reduce -0.9% 16,091 $1.3M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +22.3% 14,815 $1.2M
Y-Intercept (Hong Kong) Ltd 0.03% Add +30.3% 14,368 $1.1M
Fisher Asset Management 0.00% New 14,089 $1.1M
Polen Capital Management LLC 0.00% Add +0.2% 13,360 $1.1M
State of New Jersey Common Pension Fund D 0.00% Reduce -58.3% 12,860 $1.0M
Engineers Gate Manager LP 0.01% Reduce -37.1% 10,698 $845K
Police & Firemen's Retirement System of New Jersey 0.01% Reduce -5.8% 10,695 $845K
Virtus Investment Advisers, LLC 0.23% Add +16.0% 10,513 $830K
Arizona State Retirement System 0.00% Reduce -4.4% 10,503 $830K
Persistent Asset Partners Ltd 0.39% New 10,189 $805K
Nomura Holdings Inc. 0.00% New 9,876 $780K
STRS Ohio 0.00% Reduce -22.8% 9,800 $774K
ProShare Advisors LLC 0.00% Add +12.4% 9,774 $772K
Guggenheim Capital LLC 0.01% New 9,772 $772K
Odyssean, LLC 0.53% — 9,277 $733K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +377.6% 9,274 $733K
OP Asset Management Ltd 0.01% New 8,538 $674K
China Universal Asset Management Co., Ltd. 0.05% Reduce -4.9% 8,375 $662K
Verition Fund Management LLC 0.00% New 8,251 $652K
KLP Kapitalforvaltning As 0.00% Add +5.3% 8,000 $632K
State Board of Administration of Florida Retirement System 0.00% No change 7,947 $628K
Graham Capital Management, L.P. 0.03% Add +66.2% 7,180 $567K
PSP Research LLC 0.47% — 6,854 $541K
Man Group plc 0.00% Add +72.8% 6,841 $540K
AlphaQuest LLC 0.03% Reduce -48.0% 6,551 $517K
Great Lakes Advisors, LLC 0.00% No change 6,465 $511K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% Add +101.6% 6,450 $509K
Jasper Ridge Partners, L.P. 0.01% Reduce -23.9% 6,248 $494K
Steward Partners Investment Advisory, LLC 0.00% Add +222.7% 6,231 $492K
Cetera Investment Advisers 0.00% Add +39.0% 6,170 $487K
Dana Investment Advisors, Inc. 0.01% New 6,105 $482K
Reliant Investment Partners, LLC 0.37% Reduce -14.3% 5,975 $472K
Freestone Grove Partners LP 0.00% New 5,692 $450K
Caprock Group, LLC 0.01% Add +17.1% 5,597 $442K
Teacher Retirement System of Texas 0.00% Reduce -38.7% 5,569 $440K
LPL Financial LLC 0.00% New 5,213 $412K
Tudor Investment Corporation 0.00% Reduce -81.2% 5,205 $411K
EntryPoint Capital, LLC 0.16% Reduce -34.6% 5,150 $407K
NorthCrest Asset Manangement, LLC 0.01% New 5,369 $406K
Palumbo Wealth Management LLC 0.10% Add +19.8% 5,082 $401K
Contravisory Investment Management, Inc. 0.08% Reduce -3.7% 4,935 $390K
State of Wyoming 0.04% New 4,687 $370K
Public Employees Retirement Association of Colorado 0.00% No change 4,292 $339K
Swiss Life Asset Management Ltd 0.00% New 4,052 $320K
Virtus Advisers, LLC 0.15% No change 4,000 $316K
Acadian Asset Management LLC 0.00% New 3,872 $305K
Tidal Investments LLC 0.00% Add +32.5% 3,758 $297K
AlphaGrep UK Ltd 0.10% — 3,735 $295K
Wealth Enhancement Advisory Services, LLC 0.00% Reduce -45.5% 3,760 $292K
Ameritas Investment Partners, Inc. 0.01% No change 3,372 $266K
Ballentine Partners, LLC 0.00% Reduce -7.2% 3,324 $263K
Glenmede Trust Co. NA 0.00% — 3,315 $262K
Xponance LLC 0.00% Add +1.8% 3,206 $253K
Janney Montgomery Scott LLC 0.00% Add +6.7% 3,200 $253K
Quantinno Capital Management LP 0.00% Add +16.4% 3,192 $252K
Susquehanna International Group, LLP 0.00% Reduce -86.6% 3,160 $250K
Atria Investments, Inc 0.00% Add +5.0% 3,150 $249K
RWC Asset Management LLP 0.01% Reduce -17.5% 3,134 $248K
Lanark Financial, Inc. 0.02% Add +3.3% 3,115 $246K
Brookwood Investment Group LLC 0.03% No change 3,100 $245K
Oppenheimer Asset Management Inc. 0.00% Add +0.4% 3,087 $244K
Sumitomo Mitsui Trust Group, Inc. 0.00% New 3,038 $240K
Concurrent Investment Advisors, LLC 0.00% No change 3,000 $237K
Farallon Capital Management, L.L.C. 0.00% No change 3,000 $237K
MQS Management LLC 0.14% New 2,902 $229K
Cibc World Markets Corp. 0.00% — 2,713 $214K
Avanza Fonder AB 0.01% Reduce -11.7% 2,677 $211K
Forefront Analytics, LLC 0.19% New 2,663 $210K
Wetzel Investment Advisors, Inc. 0.08% New 2,600 $205K
Globeflex Capital L P 0.03% New 2,256 $178K
Tower Research Capital LLC (TRC) 0.00% Add +50.6% 2,159 $171K
Lazard Asset Management LLC 0.00% No change 1,981 $156K
Hollencrest Capital Management 0.01% No change 1,888 $149K
RiverPark Advisors, LLC 0.07% Add +4.7% 1,732 $137K
Rockefeller Capital Management L.P. 0.00% Add +221.0% 1,682 $133K
Osaic Holdings, Inc. 0.00% Add +40.9% 1,578 $125K
Picton Mahoney Asset Management 0.00% New 1,420 $112K
EFG International AG 0.00% — 1,355 $107K
Amalgamated Bank 0.00% Reduce -5.4% 1,288 $102K
Covestor Ltd 0.05% Add +3021.9% 1,280 $101K
KBC Group NV 0.00% No change 1,268 $100K
GF Fund Management Co. LTD. 0.00% Reduce -6.8% 1,008 $80K
Jones Financial Companies LLLP 0.00% Reduce -1.3% 945 $75K
Group One Trading LLC 0.00% Add +275.9% 872 $69K
US Bancorp \de 0.00% Reduce -50.9% 745 $59K
Cwm, LLC 0.00% Reduce -0.4% 680 $54K
Allworth Financial LP 0.00% Add +2.6% 680 $54K
Comerica Bank 0.00% Reduce -8.5% 675 $53K
PNC Financial Services Group, Inc. 0.00% Reduce -51.5% 612 $48K
Nisa Investment Advisors, LLC 0.00% Add +1.9% 477 $38K
EverSource Wealth Advisors, LLC 0.00% Reduce -2.6% 450 $36K
Parallel Advisors, LLC 0.00% No change 447 $35K
MCF Advisors LLC 0.00% Add +2.1% 436 $34K
CIBC Private Wealth Group LLC 0.00% New 401 $32K
Eurizon Capital SGR S.p.A. 0.00% — 400 $32K
Cullen/Frost Bankers, Inc. 0.00% New 383 $30K
Loring Wolcott & Coolidge Fiduciary Advisors LLP 0.00% New 278 $28K
GAMMA Investing LLC 0.00% Add +37.9% 302 $24K
Westside Investment Management, Inc. 0.00% No change 300 $24K
Sterling Capital Management LLC 0.00% Add +176.5% 271 $21K
Huntington National Bank 0.00% Add +270.6% 189 $15K
UMB Bank, n.a. 0.00% New 184 $15K
Signaturefd, LLC 0.00% Reduce -6.3% 178 $14K
HighMark Wealth Management LLC 0.01% Reduce -11.1% 160 $13K
Daiwa Securities Group Inc. 0.00% No change 158 $12K
Larson Financial Group LLC 0.00% Add +3.9% 135 $11K
Greenline Wealth Management LLC 0.01% — 126 $10K
Elequin Capital, LP 0.00% New 125 $10K
Eastern Bank 0.00% New 112 $9K
Accent Capital Management, LLC 0.00% No change 347 $8K
Kemnay Advisory Services Inc. 0.00% New 100 $8K
Smartleaf Asset Management LLC 0.00% Add +423.5% 89 $7K
MassMutual Private Wealth & Trust, FSB 0.00% Reduce -1.2% 81 $6K
True Wealth Design, LLC 0.00% No change 70 $6K
Rothschild Investment LLC 0.00% No change 65 $5K
Optiver Holding B.V. 0.00% Reduce -75.0% 60 $5K
Basecamp Wealth Advisors LLC 0.00% — 59 $5K
C M Bidwell & Associates Ltd. 0.00% New 58 $5K
Versant Capital Management, Inc 0.00% No change 58 $5K
Aventura Private Wealth, LLC 0.00% No change 45 $4K
IFP Advisors, Inc 0.00% No change 42 $3K
Farther Finance Advisors, LLC 0.00% Add +100.0% 34 $3K
Quadrant Capital Group LLC 0.00% No change 31 $2K
Bare Financial Services, Inc 0.00% Add +31.8% 29 $2K
Roble, Belko & Company, Inc 0.00% No change 19 $2K
National Bank of Canada 0.00% New 17 $1K
Parkside Financial Bank & Trust 0.00% No change 15 $1K
Creative Financial Designs Inc. 0.00% No change 11 $869
Torren Management, LLC 0.00% — 8 $632
Bell Investment Advisors, Inc 0.00% New 7 $553
Arax Advisory Partners 0.00% Reduce -98.8% 6 $474
Concord Wealth Partners 0.00% No change 5 $395
Essential Partners LLC 0.00% Reduce -28.6% 5 $395
Keating Financial Advisory Services, Inc. 0.00% — 2 $158
Bessemer Group Inc. 0.00% No change 2 $0

"% of holder's portfolio" is MIRM's weight in each manager's 13F, not the share of Mirum Pharmaceuticals Inc. the manager owns.