OmerosOMER
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 151 institutions reported holding Omeros Corp. (OMER) in their 13F filings, up 18 from Q3 2025. 31 opened new positions and 13 sold out. The largest holders were BlackRock, Inc. ($86.9M), Vanguard Group Inc. ($68.9M) and Ingalls & Snyder LLC ($59.2M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Omeros Corp.
- CUSIP
- 682143102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $19.1M |
| Exits | 13 | $5.2M |
All 13F filers, Q3 2025 → Q4 2025: 6,799,929 shares bought and 7,432,713 shares sold, net −632,784 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 151 holders
| BlackRock, Inc. | 0.00% | Add +13.7% | 5,062,438 | $86.9M |
| Vanguard Group Inc. | 0.00% | Add +19.9% | 4,013,315 | $68.9M |
| Ingalls & Snyder LLC | 2.19% | Reduce -16.0% | 3,448,699 | $59.2M |
| UBS Group AG | 0.01% | Add +213.5% | 2,222,982 | $38.2M |
| Stifel Financial Corp. | 0.03% | Reduce -0.1% | 1,809,766 | $31.1M |
| Geode Capital Management, LLC | 0.00% | Add +6.3% | 1,631,350 | $28.0M |
| State Street Corp. | 0.00% | Add +26.9% | 1,573,526 | $27.0M |
| Kotler Kevin | 11.49% | — | 905,635 | $15.6M |
| D. E. Shaw & Co. | 0.01% | Reduce -24.9% | 754,999 | $13.0M |
| Susquehanna International Group, LLP | 0.02% | Add +570.9% | 741,895 | $12.7M |
| Corient Private Wealth LP | 0.02% | Add +13.0% | 688,025 | $11.8M |
| Nomura Holdings Inc. | 0.03% | Add +1399.6% | 655,021 | $11.2M |
| Bank of Montreal | 0.00% | Add +6.8% | 601,643 | $10.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +7.2% | 593,222 | $10.2M |
| Northern Trust Corp. | 0.00% | Reduce -1.7% | 526,732 | $9.0M |
| Two Sigma Investments, LP | 0.01% | Reduce -43.8% | 524,757 | $9.0M |
| Royal Bank of Canada | 0.00% | Reduce -8.3% | 498,399 | $8.6M |
| Jane Street Group, LLC | 0.01% | Add +64.9% | 463,622 | $8.0M |
| Millennium Management | 0.01% | Add +9.9% | 441,811 | $7.6M |
| Morgan Stanley | 0.00% | Reduce -80.6% | 386,152 | $6.6M |
| Badgley Phelps Wealth Managers, LLC | 0.08% | No change | 263,556 | $4.5M |
| Citadel Advisors | 0.00% | Reduce -38.9% | 240,352 | $4.1M |
| Jump Financial, LLC | 0.05% | New | 228,000 | $3.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -32.4% | 227,294 | $3.9M |
| Informed Momentum Co LLC | 0.40% | New | 207,480 | $3.6M |
| Wellington Management Group LLP | 0.00% | Add +4.2% | 202,617 | $3.5M |
| Itau Unibanco Holding S.A. | 0.07% | New | 180,000 | $3.1M |
| Bank of New York Mellon Corp | 0.00% | Add +2.1% | 165,782 | $2.8M |
| Wells Fargo & Company | 0.00% | Add +23.3% | 165,280 | $2.8M |
| Invesco Ltd. | 0.00% | Add +26.8% | 154,782 | $2.7M |
| Nuveen, LLC | 0.00% | Add +74.8% | 153,187 | $2.6M |
| Clutterbuck Capital Management LLC | 2.20% | — | 150,000 | $2.6M |
| Group One Trading LLC | 0.07% | Add +35.6% | 133,269 | $2.3M |
| Simplex Trading, LLC | 0.06% | Add +458.0% | 123,979 | $2.1M |
| Barclays PLC | 0.00% | Reduce -8.7% | 120,490 | $2.1M |
| Ameriprise Financial Inc. | 0.00% | Add +0.4% | 117,004 | $2.0M |
| Bank of America Corp. | 0.00% | Reduce -58.3% | 114,808 | $2.0M |
| Walleye Capital LLC | 0.01% | Add +636.8% | 109,956 | $1.9M |
| HighTower Advisors, LLC | 0.00% | Add +9.3% | 104,059 | $1.8M |
| Rhumbline Advisers | 0.00% | Reduce -5.5% | 100,105 | $1.7M |
| Dimensional Fund Advisors LP | 0.00% | New | 96,948 | $1.7M |
| T. Rowe Price Associates Inc. | 0.00% | Add +6.9% | 95,745 | $1.6M |
| Susquehanna Portfolio Strategies, LLC | 0.02% | Reduce -45.8% | 92,759 | $1.6M |
| AlphaQuest LLC | 0.08% | Add +8259600.0% | 82,597 | $1.4M |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +348.1% | 81,643 | $1.4M |
| MML Investors Services, LLC | 0.00% | Add +31.6% | 77,875 | $1.3M |
| Two Sigma Advisers, LP | 0.00% | Reduce -86.8% | 76,100 | $1.3M |
| Alliancebernstein L.P. | 0.00% | Add +8.7% | 73,490 | $1.3M |
| Walleye Trading LLC | 0.02% | Add +409.4% | 69,653 | $1.2M |
| Polar Asset Management Partners Inc. | 0.03% | Reduce -95.4% | 68,800 | $1.2M |
| Brevan Howard Capital Management LP | 0.02% | Reduce -49.8% | 64,957 | $1.1M |
| American Financial Group Inc. | 0.41% | No change | 64,113 | $1.1M |
| Verition Fund Management LLC | 0.01% | New | 63,493 | $1.1M |
| Ancora Advisors LLC | 0.02% | Add +1875.0% | 59,250 | $1.0M |
| Bridgeway Capital Management, LLC | 0.02% | No change | 56,715 | $974K |
| Coldstream Capital Management Inc. | 0.01% | Add +107.5% | 53,605 | $921K |
| Mindset Wealth Management, LLC | 0.23% | Reduce -13.3% | 52,000 | $893K |
| Deutsche Bank AG | 0.00% | Add +19.3% | 48,694 | $837K |
| Cypress Capital Group | 0.08% | No change | 42,000 | $721K |
| Comerica Bank | 0.00% | Add +8.6% | 38,000 | $653K |
| JPMorgan Chase & Co. | 0.00% | Reduce -91.1% | 37,191 | $639K |
| MetLife Investment Management, LLC | 0.00% | Add +76.5% | 36,200 | $622K |
| NFSG Corp | 0.09% | Reduce -74.5% | 34,310 | $589K |
| Sei Investments Co. | 0.00% | Add +142.2% | 31,766 | $546K |
| Focus Partners Wealth | 0.00% | New | 31,034 | $533K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.3% | 30,585 | $525K |
| Cerity Partners LLC | 0.00% | Add +6.1% | 30,450 | $523K |
| Intech Investment Management LLC | 0.00% | Add +16.9% | 29,967 | $515K |
| Axq Capital, LP | 0.11% | New | 29,151 | $501K |
| Citigroup Inc. | 0.00% | Add +398.3% | 27,489 | $472K |
| Man Group plc | 0.00% | New | 27,099 | $465K |
| Virtus Investment Advisers, LLC | 0.12% | New | 26,212 | $450K |
| Quantinno Capital Management LP | 0.00% | Add +37.7% | 25,074 | $431K |
| ADAR1 Capital Management, LLC | 0.03% | New | 25,000 | $429K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +9.0% | 31,728 | $429K |
| Farallon Capital Management, L.L.C. | 0.00% | New | 23,000 | $395K |
| Stordahl Capital Management, Inc. | 0.08% | No change | 22,860 | $393K |
| AQR Capital Management | 0.00% | Add +7.2% | 22,838 | $392K |
| Harbour Investments, Inc. | 0.01% | Add +62.1% | 21,835 | $375K |
| Canada Pension Plan Investment Board | 0.00% | New | 21,700 | $373K |
| New York State Common Retirement Fund | 0.00% | Add +81.5% | 20,713 | $356K |
| Engineers Gate Manager LP | 0.00% | New | 20,082 | $345K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -0.2% | 19,850 | $341K |
| SG Americas Securities, LLC | 0.00% | Reduce -58.5% | 18,825 | $323K |
| FMR LLC | 0.00% | Add +37.0% | 18,068 | $310K |
| AlphaCore Capital LLC | 0.01% | New | 17,647 | $303K |
| Breakwater Investment Management | 0.11% | No change | 17,048 | $293K |
| Creative Planning | 0.00% | New | 16,916 | $291K |
| China Universal Asset Management Co., Ltd. | 0.02% | Reduce -24.5% | 16,553 | $284K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 16,360 | $281K |
| BNP Paribas Financial Markets | 0.00% | Reduce -81.4% | 16,351 | $281K |
| ProShare Advisors LLC | 0.00% | Add +12.1% | 15,171 | $261K |
| Profund Advisors LLC | 0.01% | New | 14,330 | $246K |
| Apella Capital, LLC | 0.00% | No change | 14,288 | $245K |
| Russell Investments Group, Ltd. | 0.00% | Add +31.0% | 14,014 | $241K |
| Los Angeles Capital Management LLC | 0.00% | New | 30,920 | $233K |
| Graham Capital Management, L.P. | 0.01% | Reduce -61.6% | 13,222 | $227K |
| Avantax Planning Partners, Inc. | 0.01% | Add +30.7% | 13,200 | $227K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 12,667 | $218K |
| Raymond James Financial Inc. | 0.00% | New | 12,242 | $210K |
"% of holder's portfolio" is OMER's weight in each manager's 13F, not the share of Omeros Corp. the manager owns.