OmerosOMER

13F holders, Q4 2025 (December 31)
151holders +18
31new positions
13sold out
4famous investors
$17.16avg. 13F price*

At the end of Q4 2025, 151 institutions reported holding Omeros Corp. (OMER) in their 13F filings, up 18 from Q3 2025. 31 opened new positions and 13 sold out. The largest holders were BlackRock, Inc. ($86.9M), Vanguard Group Inc. ($68.9M) and Ingalls & Snyder LLC ($59.2M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Omeros Corp.
CUSIP
682143102
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 99Q1 2024Q2 2024: 104Q2 2024Q3 2024: 108Q3 2024Q4 2024: 128Q4 2024Q1 2025: 137Q1 2025Q2 2025: 127Q2 2025Q3 2025: 133Q3 2025Q4 2025: 151Q4 2025Q1 2026: 162Q1 2026Q2 2026: 171Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions31$19.1M
Exits13$5.2M

All 13F filers, Q3 2025 → Q4 2025: 6,799,929 shares bought and 7,432,713 shares sold, net −632,784 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 151 holders

BlackRock, Inc. 0.00% Add +13.7% 5,062,438 $86.9M
Vanguard Group Inc. 0.00% Add +19.9% 4,013,315 $68.9M
Ingalls & Snyder LLC 2.19% Reduce -16.0% 3,448,699 $59.2M
UBS Group AG 0.01% Add +213.5% 2,222,982 $38.2M
Stifel Financial Corp. 0.03% Reduce -0.1% 1,809,766 $31.1M
Geode Capital Management, LLC 0.00% Add +6.3% 1,631,350 $28.0M
State Street Corp. 0.00% Add +26.9% 1,573,526 $27.0M
Kotler Kevin 11.49% — 905,635 $15.6M
D. E. Shaw & Co. 0.01% Reduce -24.9% 754,999 $13.0M
Susquehanna International Group, LLP 0.02% Add +570.9% 741,895 $12.7M
Corient Private Wealth LP 0.02% Add +13.0% 688,025 $11.8M
Nomura Holdings Inc. 0.03% Add +1399.6% 655,021 $11.2M
Bank of Montreal 0.00% Add +6.8% 601,643 $10.3M
Charles Schwab Investment Management Inc. 0.00% Add +7.2% 593,222 $10.2M
Northern Trust Corp. 0.00% Reduce -1.7% 526,732 $9.0M
Two Sigma Investments, LP 0.01% Reduce -43.8% 524,757 $9.0M
Royal Bank of Canada 0.00% Reduce -8.3% 498,399 $8.6M
Jane Street Group, LLC 0.01% Add +64.9% 463,622 $8.0M
Millennium Management 0.01% Add +9.9% 441,811 $7.6M
Morgan Stanley 0.00% Reduce -80.6% 386,152 $6.6M
Badgley Phelps Wealth Managers, LLC 0.08% No change 263,556 $4.5M
Citadel Advisors 0.00% Reduce -38.9% 240,352 $4.1M
Jump Financial, LLC 0.05% New 228,000 $3.9M
Goldman Sachs Group Inc. 0.00% Reduce -32.4% 227,294 $3.9M
Informed Momentum Co LLC 0.40% New 207,480 $3.6M
Wellington Management Group LLP 0.00% Add +4.2% 202,617 $3.5M
Itau Unibanco Holding S.A. 0.07% New 180,000 $3.1M
Bank of New York Mellon Corp 0.00% Add +2.1% 165,782 $2.8M
Wells Fargo & Company 0.00% Add +23.3% 165,280 $2.8M
Invesco Ltd. 0.00% Add +26.8% 154,782 $2.7M
Nuveen, LLC 0.00% Add +74.8% 153,187 $2.6M
Clutterbuck Capital Management LLC 2.20% — 150,000 $2.6M
Group One Trading LLC 0.07% Add +35.6% 133,269 $2.3M
Simplex Trading, LLC 0.06% Add +458.0% 123,979 $2.1M
Barclays PLC 0.00% Reduce -8.7% 120,490 $2.1M
Ameriprise Financial Inc. 0.00% Add +0.4% 117,004 $2.0M
Bank of America Corp. 0.00% Reduce -58.3% 114,808 $2.0M
Walleye Capital LLC 0.01% Add +636.8% 109,956 $1.9M
HighTower Advisors, LLC 0.00% Add +9.3% 104,059 $1.8M
Rhumbline Advisers 0.00% Reduce -5.5% 100,105 $1.7M
Dimensional Fund Advisors LP 0.00% New 96,948 $1.7M
T. Rowe Price Associates Inc. 0.00% Add +6.9% 95,745 $1.6M
Susquehanna Portfolio Strategies, LLC 0.02% Reduce -45.8% 92,759 $1.6M
AlphaQuest LLC 0.08% Add +8259600.0% 82,597 $1.4M
Cambridge Investment Research Advisors, Inc. 0.00% Add +348.1% 81,643 $1.4M
MML Investors Services, LLC 0.00% Add +31.6% 77,875 $1.3M
Two Sigma Advisers, LP 0.00% Reduce -86.8% 76,100 $1.3M
Alliancebernstein L.P. 0.00% Add +8.7% 73,490 $1.3M
Walleye Trading LLC 0.02% Add +409.4% 69,653 $1.2M
Polar Asset Management Partners Inc. 0.03% Reduce -95.4% 68,800 $1.2M
Brevan Howard Capital Management LP 0.02% Reduce -49.8% 64,957 $1.1M
American Financial Group Inc. 0.41% No change 64,113 $1.1M
Verition Fund Management LLC 0.01% New 63,493 $1.1M
Ancora Advisors LLC 0.02% Add +1875.0% 59,250 $1.0M
Bridgeway Capital Management, LLC 0.02% No change 56,715 $974K
Coldstream Capital Management Inc. 0.01% Add +107.5% 53,605 $921K
Mindset Wealth Management, LLC 0.23% Reduce -13.3% 52,000 $893K
Deutsche Bank AG 0.00% Add +19.3% 48,694 $837K
Cypress Capital Group 0.08% No change 42,000 $721K
Comerica Bank 0.00% Add +8.6% 38,000 $653K
JPMorgan Chase & Co. 0.00% Reduce -91.1% 37,191 $639K
MetLife Investment Management, LLC 0.00% Add +76.5% 36,200 $622K
NFSG Corp 0.09% Reduce -74.5% 34,310 $589K
Sei Investments Co. 0.00% Add +142.2% 31,766 $546K
Focus Partners Wealth 0.00% New 31,034 $533K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +1.3% 30,585 $525K
Cerity Partners LLC 0.00% Add +6.1% 30,450 $523K
Intech Investment Management LLC 0.00% Add +16.9% 29,967 $515K
Axq Capital, LP 0.11% New 29,151 $501K
Citigroup Inc. 0.00% Add +398.3% 27,489 $472K
Man Group plc 0.00% New 27,099 $465K
Virtus Investment Advisers, LLC 0.12% New 26,212 $450K
Quantinno Capital Management LP 0.00% Add +37.7% 25,074 $431K
ADAR1 Capital Management, LLC 0.03% New 25,000 $429K
Wealth Enhancement Advisory Services, LLC 0.00% Add +9.0% 31,728 $429K
Farallon Capital Management, L.L.C. 0.00% New 23,000 $395K
Stordahl Capital Management, Inc. 0.08% No change 22,860 $393K
AQR Capital Management 0.00% Add +7.2% 22,838 $392K
Harbour Investments, Inc. 0.01% Add +62.1% 21,835 $375K
Canada Pension Plan Investment Board 0.00% New 21,700 $373K
New York State Common Retirement Fund 0.00% Add +81.5% 20,713 $356K
Engineers Gate Manager LP 0.00% New 20,082 $345K
Manufacturers Life Insurance Company, The 0.00% Reduce -0.2% 19,850 $341K
SG Americas Securities, LLC 0.00% Reduce -58.5% 18,825 $323K
FMR LLC 0.00% Add +37.0% 18,068 $310K
AlphaCore Capital LLC 0.01% New 17,647 $303K
Breakwater Investment Management 0.11% No change 17,048 $293K
Creative Planning 0.00% New 16,916 $291K
China Universal Asset Management Co., Ltd. 0.02% Reduce -24.5% 16,553 $284K
Police & Firemen's Retirement System of New Jersey 0.00% No change 16,360 $281K
BNP Paribas Financial Markets 0.00% Reduce -81.4% 16,351 $281K
ProShare Advisors LLC 0.00% Add +12.1% 15,171 $261K
Profund Advisors LLC 0.01% New 14,330 $246K
Apella Capital, LLC 0.00% No change 14,288 $245K
Russell Investments Group, Ltd. 0.00% Add +31.0% 14,014 $241K
Los Angeles Capital Management LLC 0.00% New 30,920 $233K
Graham Capital Management, L.P. 0.01% Reduce -61.6% 13,222 $227K
Avantax Planning Partners, Inc. 0.01% Add +30.7% 13,200 $227K
Schonfeld Strategic Advisors LLC 0.00% New 12,667 $218K
Raymond James Financial Inc. 0.00% New 12,242 $210K
Rafferty Asset Management, LLC 0.00% New 12,226 $210K
Voya Investment Management LLC 0.00% Add +1.9% 11,405 $196K
B. Riley Wealth Advisors, Inc. 0.01% Add +5.7% 11,369 $195K
Sowell Financial Services LLC 0.01% Add +1.9% 10,650 $183K
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 0.00% Reduce -74.1% 10,500 $180K
Abel Hall, LLC 0.04% New 10,240 $176K
Caitong International Asset Management Co., Ltd 0.04% New 9,276 $159K
Osaic Holdings, Inc. 0.00% Add +34.5% 7,547 $130K
Quantbot Technologies LP 0.00% New 7,220 $124K
Farther Finance Advisors, LLC 0.00% Add +16.4% 7,106 $122K
Legal & General Group Plc 0.00% Reduce -1.6% 6,971 $120K
Vontobel Holding Ltd. 0.00% New 5,450 $94K
Arax Advisory Partners 0.00% Add +56.4% 5,255 $90K
Ameritas Investment Partners, Inc. 0.00% No change 5,027 $86K
International Assets Investment Management, LLC 0.01% Reduce -67.8% 5,000 $86K
California State Teachers Retirement System 0.00% Reduce -0.0% 4,055 $70K
Parallel Advisors, LLC 0.00% Add +23.7% 3,909 $67K
Optiver Holding B.V. 0.00% Add +596.5% 3,747 $64K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +30.9% 3,445 $59K
Amalgamated Bank 0.00% Add +0.8% 2,069 $36K
Tower Research Capital LLC (TRC) 0.00% Reduce -44.1% 1,916 $33K
Strategic Investment Solutions, Inc. 0.01% Add +0.1% 1,827 $31K
Truvestments Capital LLC 0.01% No change 1,682 $29K
State of Wyoming 0.00% New 1,433 $25K
GF Fund Management Co. LTD. 0.00% Reduce -4.9% 1,392 $24K
Cwm, LLC 0.00% Reduce -2.2% 1,232 $21K
Plante Moran Financial Advisors, LLC 0.00% No change 1,000 $17K
Fifth Third Bancorp 0.00% No change 1,000 $17K
NewEdge Advisors, LLC 0.00% New 1,000 $17K
Capital Analysts, LLC 0.00% No change 1,000 $17K
Sterling Capital Management LLC 0.00% Add +39.7% 901 $15K
Nisa Investment Advisors, LLC 0.00% Reduce -52.0% 804 $14K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -23.5% 765 $13K
Northwestern Mutual Wealth Management Co. 0.00% No change 500 $9K
PNC Financial Services Group, Inc. 0.00% Reduce -44.1% 377 $6K
MassMutual Private Wealth & Trust, FSB 0.00% Add +190.3% 360 $6K
Pandora Wealth, Inc. 0.00% No change 330 $6K
Federation des caisses Desjardins du Quebec 0.00% No change 300 $5K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 231 $4K
SBI Securities Co., Ltd. 0.00% No change 208 $4K
Rockefeller Capital Management L.P. 0.00% New 195 $3K
Daiwa Securities Group Inc. 0.00% No change 191 $3K
Larson Financial Group LLC 0.00% Add +0.7% 151 $3K
EverSource Wealth Advisors, LLC 0.00% No change 115 $2K
GAMMA Investing LLC 0.00% New 107 $2K
Rothschild Investment LLC 0.00% New 60 $1K
SRH Advisors, LLC 0.00% No change 50 $859
Allworth Financial LP 0.00% Reduce -22.8% 44 $756
Parkside Financial Bank & Trust 0.00% New 40 $687
IFP Advisors, Inc 0.00% No change 26 $447
Essential Partners LLC 0.00% No change 11 $189

"% of holder's portfolio" is OMER's weight in each manager's 13F, not the share of Omeros Corp. the manager owns.