Opko HealthOPK
13F holders, Q1 2026 (March 31)236holders +15
35new positions
22sold out
6famous investors
$1.14avg. 13F price*
At the end of Q1 2026, 236 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 15 from Q4 2025. 35 opened new positions and 22 sold out. The largest holders were Rubric Capital Management LP ($54.5M), BlackRock, Inc. ($41.3M) and Vanguard Portfolio Management LLC ($16.8M). 6 famous investors held it, including Mario Gabelli (0.0% of GAMCO Investors's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 35 | $3.7M |
| Exits | 22 | $1.8M |
All 13F filers, Q4 2025 → Q1 2026: 10,012,437 shares bought and 8,341,568 shares sold, net +1,670,869 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 236 holders
| Rubric Capital Management LP | 0.67% | No change | 47,791,243 | $54.5M |
| BlackRock, Inc. | 0.00% | Add +4.0% | 36,232,223 | $41.3M |
| Vanguard Portfolio Management LLC | 0.00% | — | 14,769,719 | $16.8M |
| Vanguard Capital Management LLC | 0.00% | — | 14,499,164 | $16.5M |
| Geode Capital Management, LLC | 0.00% | Add +2.2% | 11,301,501 | $12.9M |
| State Street Corp. | 0.00% | Add +6.1% | 9,501,377 | $10.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +28.2% | 7,675,026 | $8.7M |
| UBS Group AG | 0.00% | Add +13.4% | 6,071,432 | $6.9M |
| Whitefort Capital Management, LP | 1.53% | No change | 4,253,340 | $4.8M |
| Northern Trust Corp. | 0.00% | Add +5.3% | 3,619,346 | $4.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.2% | 3,574,039 | $4.1M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 2,742,017 | $3.1M |
| AWM Investment Company, Inc. | 0.27% | No change | 2,100,000 | $2.4M |
| Citadel Advisors | 0.00% | Reduce -27.2% | 2,079,547 | $2.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -3.2% | 1,560,000 | $1.8M |
| Washington Growth Strategies LLC | 1.01% | No change | 1,356,124 | $1.5M |
| Y.D. More Investments Ltd | 0.06% | Reduce -0.5% | 1,299,473 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.3% | 1,280,042 | $1.5M |
| Morgan Stanley | 0.00% | Add +30.4% | 1,196,087 | $1.4M |
| Voya Investment Management LLC | 0.00% | Add +5.3% | 1,160,927 | $1.3M |
| Bank of America Corp. | 0.00% | Add +84.7% | 1,141,849 | $1.3M |
| Jane Street Group, LLC | 0.00% | Reduce -37.2% | 1,114,375 | $1.3M |
| PFG Investments, LLC | 0.06% | Reduce -15.7% | 1,112,776 | $1.3M |
| OP Asset Management Ltd | 0.01% | New | 1,102,254 | $1.3M |
| Clearstead Advisors, LLC | 0.01% | Add +0.2% | 884,119 | $1.0M |
| Tejara Capital Ltd | 0.33% | No change | 877,941 | $1.0M |
| Nuveen, LLC | 0.00% | Add +0.6% | 846,993 | $966K |
| Swiss National Bank | 0.00% | No change | 845,755 | $964K |
| Invesco Ltd. | 0.00% | Add +1.5% | 793,169 | $904K |
| AQR Capital Management | 0.00% | Reduce -62.3% | 763,590 | $870K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.2% | 674,848 | $769K |
| Gsa Capital Partners LLP | 0.05% | Add +6.8% | 663,704 | $757K |
| Assenagon Asset Management S.A. | 0.00% | No change | 652,066 | $740K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +21.4% | 522,906 | $596K |
| First Trust Advisors LP | 0.00% | New | 500,273 | $570K |
| Rhumbline Advisers | 0.00% | Reduce -2.8% | 497,240 | $567K |
| JPMorgan Chase & Co. | 0.00% | Reduce -12.3% | 508,484 | $559K |
| Alliancebernstein L.P. | 0.00% | Reduce -5.6% | 423,190 | $533K |
| Kovack Advisors, Inc. | 0.03% | New | 459,700 | $524K |
| XTX Topco Ltd | 0.01% | Add +25.7% | 430,966 | $491K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -32.8% | 430,906 | $491K |
| California State Teachers Retirement System | 0.00% | Reduce -0.7% | 414,037 | $472K |
| T. Rowe Price Associates Inc. | 0.00% | Add +10.2% | 404,652 | $462K |
| Qube Research & Technologies Ltd | 0.00% | Add +293.5% | 404,358 | $461K |
| Susquehanna International Group, LLP | 0.00% | Reduce -10.5% | 391,516 | $446K |
| Deutsche Bank AG | 0.00% | Add +13.8% | 370,948 | $423K |
| Legal & General Group Plc | 0.00% | Reduce -24.2% | 343,474 | $392K |
| EntryPoint Capital, LLC | 0.11% | Add +10.7% | 342,171 | $390K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 294,013 | $335K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $279K |
| HSBC Holdings PLC | 0.00% | New | 238,281 | $273K |
| Royal Bank of Canada | 0.00% | Reduce -15.7% | 219,994 | $251K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $236K |
| MetLife Investment Management, LLC | 0.00% | Add +16.5% | 204,738 | $233K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +3.6% | 197,906 | $226K |
| Vanguard Global Advisers, LLC | 0.00% | — | 181,766 | $207K |
| Creative Planning | 0.00% | Add +204.8% | 176,985 | $202K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $201K |
| GAMCO Investors | 0.00% | No change | 175,000 | $200K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $194K |
| Two Sigma Investments, LP | 0.00% | Reduce -76.9% | 170,000 | $194K |
| State of Wyoming | 0.02% | New | 167,020 | $190K |
| Wells Fargo & Company | 0.00% | Reduce -65.3% | 162,609 | $185K |
| Van Eck Associates Corp. | 0.00% | Add +16.8% | 160,096 | $183K |
| Zazove Associates LLC | 0.31% | No change | 150,000 | $171K |
| ProShare Advisors LLC | 0.00% | Reduce -10.0% | 140,658 | $160K |
| Teton Advisors, LLC | 0.11% | No change | 140,000 | $160K |
| Barclays PLC | 0.00% | Reduce -79.2% | 138,300 | $158K |
| U.S. Capital Wealth Advisors, LLC | 0.00% | New | 133,261 | $152K |
| Fifth Third Bancorp | 0.00% | New | 128,791 | $147K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1310.1% | 128,713 | $147K |
| Intech Investment Management LLC | 0.00% | Reduce -21.2% | 125,814 | $143K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -46.8% | 122,128 | $139K |
| Highline Wealth Partners LLC | 0.03% | Reduce 0.0% | 116,680 | $133K |
| Arizona State Retirement System | 0.00% | Add +1.9% | 115,978 | $132K |
| New York State Common Retirement Fund | 0.00% | No change | 114,301 | $130K |
| Glenmede Trust Co. NA | 0.00% | Reduce -0.7% | 112,750 | $129K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 110,958 | $126K |
| Renaissance Technologies | 0.00% | New | 109,543 | $125K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 102,397 | $117K |
| 360 Financial, Inc. | 0.03% | Add +11.4% | 97,300 | $111K |
| Ameriprise Financial Inc. | 0.00% | Add +0.5% | 96,722 | $110K |
| Point72 Asset Management | 0.00% | New | 93,335 | $106K |
| Ieq Capital, LLC | 0.00% | Reduce -40.9% | 93,222 | $106K |
| KLP Kapitalforvaltning As | 0.00% | No change | 90,700 | $103K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.6% | 90,279 | $103K |
| HRT Financial LP | 0.00% | Reduce -86.6% | 90,759 | $103K |
| BNP Paribas Financial Markets | 0.00% | Reduce -0.8% | 89,732 | $102K |
| Quadrature Capital Ltd | 0.00% | Reduce -3.0% | 88,937 | $101K |
| RPg Family Wealth Advisory, LLC | 0.02% | Reduce -10.5% | 88,619 | $101K |
| SG Americas Securities, LLC | 0.00% | Add +62.6% | 87,846 | $100K |
| Cwm, LLC | 0.00% | Add +1.0% | 69,834 | $80K |
| World Investment Advisors | 0.00% | No change | 66,520 | $76K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $76K |
| Prudential Financial Inc. | 0.00% | Add +148.6% | 65,556 | $75K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $75K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +8.4% | 62,365 | $71K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $70K |
| Cetera Investment Advisers | 0.00% | Add +0.3% | 59,352 | $68K |
| Kestra Private Wealth Services, LLC | 0.00% | No change | 58,450 | $67K |
| Headlands Technologies LLC | 0.01% | Reduce -36.5% | 56,480 | $64K |
| Private Advisor Group, LLC | 0.00% | No change | 55,301 | $63K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 55,140 | $63K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 54,068 | $62K |
| Graham Capital Management, L.P. | 0.00% | Reduce -55.8% | 52,859 | $60K |
| Mercer Global Advisors Inc. | 0.00% | Reduce -10.5% | 52,832 | $60K |
| First Manhattan Co. Llc. | 0.00% | Add +0.8% | 52,150 | $59K |
| Transcend Capital Advisors, LLC | 0.00% | Reduce -1.6% | 51,905 | $59K |
| Farmers National Bank | 0.01% | No change | 50,300 | $57K |
| Osaic Holdings, Inc. | 0.00% | Reduce -36.7% | 47,667 | $54K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -46.2% | 45,919 | $52K |
| LGL Partners, LLC | 0.02% | New | 44,507 | $51K |
| Victory Capital Management Inc. | 0.00% | Reduce -1.7% | 44,268 | $50K |
| FMR LLC | 0.00% | Add +193.5% | 41,343 | $47K |
| Group One Trading LLC | 0.00% | New | 40,662 | $46K |
| Captrust Financial Advisors | 0.00% | Add +0.5% | 40,306 | $46K |
| Hollencrest Capital Management | 0.00% | No change | 40,000 | $46K |
| Mariner, LLC | 0.00% | Reduce -6.8% | 39,346 | $45K |
| Brighton Jones LLC | 0.00% | New | 37,950 | $43K |
| Xponance LLC | 0.00% | Add +15.2% | 37,294 | $43K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 37,000 | $42K |
| State of Wisconsin Investment Board | 0.00% | Add +31.3% | 34,714 | $40K |
| Choreo, LLC | 0.00% | No change | 33,757 | $38K |
| Citigroup Inc. | 0.00% | Add +103.6% | 33,676 | $38K |
| HighTower Advisors, LLC | 0.00% | Reduce -11.1% | 33,311 | $38K |
| Abel Hall, LLC | 0.01% | New | 33,271 | $38K |
| Raymond James Financial Inc. | 0.00% | Reduce -15.8% | 32,624 | $37K |
| Waverly Advisors, LLC | 0.00% | Reduce -6.3% | 32,556 | $37K |
| Operose Advisors LLC | 0.01% | No change | 32,000 | $36K |
| STRS Ohio | 0.00% | No change | 31,900 | $36K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 31,889 | $36K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -8.3% | 31,816 | $36K |
| EP Wealth Advisors, LLC | 0.00% | Add +2.5% | 30,170 | $34K |
| Wellington Grp LLC | 0.01% | Reduce -50.0% | 30,000 | $34K |
| IPG Investment Advisors LLC | 0.01% | No change | 30,000 | $34K |
| Apella Capital, LLC | 0.00% | New | 27,021 | $34K |
| Diversify Wealth Management, LLC | 0.00% | No change | 30,000 | $33K |
| Swiss Life Asset Management Ltd | 0.00% | Add +48.6% | 28,488 | $32K |
| LPL Financial LLC | 0.00% | Add +25.4% | 28,158 | $32K |
| SlateStone Wealth, LLC | 0.00% | No change | 25,770 | $29K |
| Arrow Financial Corp | 0.00% | No change | 25,000 | $29K |
| Mirabella Financial Services LLP | 0.00% | Reduce -87.1% | 24,906 | $28K |
| Zacks Investment Management | 0.00% | Add +15.7% | 24,665 | $28K |
| Cerity Partners LLC | 0.00% | Add +35.0% | 23,471 | $27K |
| Sax Wealth Advisors, LLC | 0.00% | Reduce -0.5% | 20,188 | $25K |
| CIBC Asset Management Inc | 0.00% | No change | 21,918 | $25K |
| CIBC Bancorp USA Inc. | 0.00% | — | 20,721 | $24K |
| Spartan Wealth Advisory Services LLC | 0.00% | — | 20,000 | $23K |
| Capital Advisors Inc. | 0.00% | Reduce -94.6% | 20,000 | $23K |
| Cumberland Advisors Inc. | 0.01% | No change | 19,500 | $22K |
| Westmount Partners, LLC | 0.01% | No change | 18,550 | $21K |
| Principal Financial Group Inc. | 0.00% | Reduce -0.1% | 17,740 | $20K |
| Cibc World Market Inc. | 0.00% | No change | 17,228 | $20K |
| Blueshift Asset Management, LLC | 0.01% | New | 17,036 | $19K |
| Shufro Rose & Co. LLC | 0.00% | No change | 17,000 | $19K |
| Caprock Group, LLC | 0.00% | No change | 16,770 | $19K |
| SIH Partners, LLLP | 0.00% | Reduce -84.0% | 16,687 | $19K |
| Jones Financial Companies LLLP | 0.00% | Add +18.1% | 16,675 | $19K |
| Commons Capital, LLC | 0.02% | No change | 16,300 | $19K |
| Sequoia Financial Advisors, LLC | 0.00% | New | 16,264 | $19K |
| Sigma Planning Corp | 0.00% | No change | 15,807 | $18K |
| Stifel Financial Corp. | 0.00% | Add +1.2% | 15,549 | $18K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | No change | 14,823 | $17K |
| Colony Family Offices, LLC | 0.00% | No change | 14,729 | $17K |
| Altshuler Shaham Ltd | 0.00% | Add +348.8% | 14,775 | $17K |
| Mill Creek Capital Advisors, LLC | 0.00% | Add +16.1% | 14,383 | $16K |
| Sterling Capital Management LLC | 0.00% | Reduce -42.2% | 13,716 | $16K |
| Moody National Bank Trust Division | 0.00% | New | 13,554 | $15K |
| Key Financial Inc | 0.00% | Reduce -13.1% | 13,250 | $15K |
| Amalgamated Bank | 0.00% | No change | 12,929 | $15K |
| Compound Planning, Inc. | 0.00% | Add +8.7% | 12,501 | $14K |
| Traphagen Investment Advisors LLC | 0.00% | No change | 11,680 | $13K |
| Allworth Financial LP | 0.00% | Add +43.1% | 11,661 | $13K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 11,596 | $13K |
| Formidable Asset Management, LLC | 0.00% | Reduce -8.8% | 10,296 | $13K |
| Focus Partners Wealth | 0.00% | New | 11,100 | $13K |
| HBK Sorce Advisory LLC | 0.00% | No change | 11,057 | $13K |
| IMC-Chicago, LLC | 0.00% | New | 10,874 | $12K |
| Frec Markets, Inc. | 0.00% | New | 10,542 | $12K |
| Sei Investments Co. | 0.00% | No change | 10,163 | $12K |
| Diversified Trust Co. | 0.00% | Reduce -2.4% | 10,122 | $12K |
| First Affirmative Financial Network | 0.00% | — | 10,108 | $12K |
| MRP Capital Investments, LLC | 0.01% | No change | 10,000 | $11K |
| Greenbush Financial Group, LLC | 0.00% | No change | 10,000 | $11K |
| KLCM Advisors, Inc. | 0.00% | No change | 10,000 | $11K |
| Florida Trust Wealth Management Co | 0.00% | New | 10,000 | $11K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +52.5% | 9,221 | $11K |
| Quantbot Technologies LP | 0.00% | Reduce -92.8% | 8,902 | $10K |
| Aventura Private Wealth, LLC | 0.00% | No change | 8,400 | $10K |
| Simplex Trading, LLC | 0.00% | Reduce -92.2% | 7,320 | $8K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 7,110 | $8K |
| National Bank of Canada | 0.00% | Reduce -16.1% | 5,200 | $6K |
| Aquatic Capital Management LLC | 0.00% | New | 4,166 | $5K |
| Parallel Advisors, LLC | 0.00% | New | 3,649 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -37.2% | 3,534 | $4K |
| Nisa Investment Advisors, LLC | 0.00% | Add +158.2% | 3,388 | $4K |
| Gables Capital Management Inc. | 0.00% | No change | 3,000 | $3K |
| Farther Finance Advisors, LLC | 0.00% | Add +2426.8% | 2,729 | $3K |
| Smartleaf Asset Management LLC | 0.00% | No change | 2,757 | $3K |
| Essential Partners LLC | 0.00% | Add +28.6% | 2,207 | $3K |
| Signaturefd, LLC | 0.00% | New | 2,022 | $2K |
| Harbour Investments, Inc. | 0.00% | New | 2,000 | $2K |
| Optiver Holding B.V. | 0.00% | Add +27.7% | 1,779 | $2K |
| CoreCap Advisors, LLC | 0.00% | No change | 1,600 | $2K |
| GAMMA Investing LLC | 0.00% | New | 1,334 | $2K |
| Godfrey Financial Associates, Inc. | 0.00% | No change | 1,250 | $1K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -42.8% | 806 | $1K |
| PFS Partners, LLC | 0.00% | No change | 1,100 | $1K |
| Rockefeller Capital Management L.P. | 0.00% | Add +162.6% | 1,053 | $1K |
| Salomon & Ludwin, LLC | 0.00% | Reduce -4.8% | 877 | $1K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -97.9% | 833 | $950 |
| True Wealth Design, LLC | 0.00% | Reduce -35.9% | 559 | $638 |
| Rothschild Investment LLC | 0.00% | Add +22.9% | 552 | $629 |
| IFP Advisors, Inc | 0.00% | Reduce -6.7% | 403 | $459 |
| Arax Advisory Partners | 0.00% | New | 293 | $334 |
| Quadrant Capital Group LLC | 0.00% | New | 272 | $311 |
| Pittenger & Anderson Inc. | 0.00% | No change | 250 | $285 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -0.4% | 227 | $259 |
| Hilton Head Capital Partners, LLC | 0.00% | No change | 200 | $228 |
| Harbor Investment Advisory, LLC | 0.00% | No change | 180 | $205 |
| Salem Investment Counselors Inc. | 0.00% | New | 100 | $114 |
| Root Financial Partners, LLC | 0.00% | No change | 100 | $114 |
| Boreal Capital Management LLC | 0.00% | No change | 69 | $79 |
| Sunbelt Securities, Inc. | 0.00% | New | 55 | $63 |
| MAI Capital Management | 0.00% | New | 43 | $50 |
| Larson Financial Group LLC | 0.00% | No change | 40 | $46 |
| SJS Investment Consulting Inc. | 0.00% | New | 24 | $28 |
| Dunhill Financial, LLC | 0.00% | Reduce -11.1% | 8 | $9 |
| Darwin Wealth Management, LLC | 0.00% | No change | 5 | $5 |
| Wilkerson Advisory Group LLC | 0.00% | New | 4 | $5 |
| Crewe Advisors LLC | 0.00% | No change | 1 | $2 |
| SBI Securities Co., Ltd. | 0.00% | No change | 2 | $2 |
| LRI Investments, LLC | 0.00% | No change | 1 | $1 |
| Keating Financial Advisory Services, Inc. | 0.00% | New | 1 | $1 |
| Centerpoint Advisors, LLC | 0.00% | No change | 100 | $0 |
| Covestor Ltd | 0.00% | No change | 72 | $0 |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.