Pliant TherapeuticsPLRX
13F holders, Q4 2025 (December 31)98holders −1
10new positions
13sold out
5famous investors
$1.23avg. 13F price*
At the end of Q4 2025, 98 institutions reported holding Pliant Therapeutics Inc. (PLRX) in their 13F filings, down 1 from Q3 2025. 10 opened new positions and 13 sold out. The largest holders were Tang Capital Management LLC ($7.5M), Blue Owl Capital Holdings LP ($3.6M) and Vanguard Group Inc. ($3.4M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Pliant Therapeutics Inc.
- CUSIP
- 729139105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 10 | $3.9M |
| Exits | 13 | $1.7M |
All 13F filers, Q3 2025 → Q4 2025: 9,611,878 shares bought and 13,856,409 shares sold, net −4,244,531 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 98 holders
| Tang Capital Management LLC | 0.37% | Add +2.3% | 6,143,132 | $7.5M |
| Blue Owl Capital Holdings LP | 1.13% | No change | 2,969,199 | $3.6M |
| Vanguard Group Inc. | 0.00% | Add +1.5% | 2,818,241 | $3.4M |
| Citadel Advisors | 0.00% | Add +10.4% | 2,583,332 | $3.2M |
| Acadian Asset Management LLC | 0.00% | Reduce -0.2% | 2,364,669 | $2.9M |
| Woodline Partners LP | 0.01% | Reduce -55.0% | 2,026,191 | $2.5M |
| Monaco Asset Management SAM | 0.72% | Add +135.7% | 1,938,747 | $2.4M |
| Redmile Group, LLC | 0.15% | Add +1.5% | 1,616,228 | $2.0M |
| Prosight Management, LP | 0.39% | Add +7493.8% | 1,555,744 | $1.9M |
| BML Capital Management, LLC | 1.67% | New | 1,546,137 | $1.9M |
| Two Sigma Advisers, LP | 0.00% | Add +16.1% | 1,245,600 | $1.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -43.1% | 1,212,875 | $1.5M |
| Marshall Wace, LLP | 0.00% | Add +260.7% | 1,080,128 | $1.3M |
| BlackRock, Inc. | 0.00% | Reduce -24.5% | 1,073,272 | $1.3M |
| UBS Group AG | 0.00% | Reduce -19.6% | 1,062,615 | $1.3M |
| Renaissance Technologies | 0.00% | Add +3.4% | 1,045,818 | $1.3M |
| Centiva Capital, LP | 0.07% | New | 1,000,000 | $1.2M |
| Two Sigma Investments, LP | 0.00% | Add +21.7% | 953,293 | $1.2M |
| Peapod Lane Capital LLC | 0.92% | Reduce -19.2% | 886,374 | $1.1M |
| Eversept Partners, LP | 0.06% | Add +2.1% | 842,023 | $1.0M |
| Bank of America Corp. | 0.00% | Add +0.5% | 711,777 | $868K |
| Jane Street Group, LLC | 0.00% | Add +71.9% | 653,774 | $798K |
| Gsa Capital Partners LLP | 0.07% | Add +287.7% | 623,698 | $761K |
| Geode Capital Management, LLC | 0.00% | Add +0.9% | 592,696 | $723K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Add +51.7% | 556,938 | $679K |
| Morgan Stanley | 0.00% | Reduce -84.3% | 548,962 | $670K |
| XTX Topco Ltd | 0.02% | Add +16.7% | 545,016 | $665K |
| Bessemer Group Inc. | 0.00% | No change | 532,079 | $649K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $633K |
| Millennium Management | 0.00% | Reduce -23.9% | 408,831 | $499K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +1428.2% | 371,951 | $454K |
| Bridgeway Capital Management, LLC | 0.01% | Add +290.7% | 321,530 | $392K |
| Torno Capital, LLC | 0.17% | Add +144.4% | 320,000 | $390K |
| Sei Investments Co. | 0.00% | No change | 297,291 | $363K |
| ArrowMark Colorado Holdings LLC | 0.01% | No change | 281,189 | $343K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -50.1% | 276,866 | $338K |
| Seven Fleet Capital Management LP | 0.23% | — | 276,500 | $337K |
| Laurion Capital Management LP | 0.02% | New | 257,400 | $314K |
| State Street Corp. | 0.00% | Reduce -0.2% | 253,418 | $309K |
| Nano Cap New Millennium Growth Fund L P | 0.24% | — | 235,000 | $287K |
| Stonepine Capital Management, LLC | 0.22% | Reduce -20.5% | 230,050 | $281K |
| Rangeley Capital, LLC | 0.24% | Add +273.6% | 225,000 | $275K |
| HighMark Wealth Management LLC | 0.09% | Reduce -21.9% | 170,924 | $209K |
| Rice Hall James & Associates, LLC | 0.01% | Add +2.0% | 147,705 | $180K |
| Diadema Partners LP | 0.11% | New | 144,914 | $177K |
| Northern Trust Corp. | 0.00% | Reduce -9.7% | 123,273 | $150K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -19.7% | 121,756 | $149K |
| Osaic Holdings, Inc. | 0.00% | Reduce -8.3% | 114,971 | $140K |
| Invesco Ltd. | 0.00% | Add +6.4% | 113,934 | $139K |
| Hennion & Walsh Asset Management, Inc. | 0.00% | Add +15.7% | 113,383 | $138K |
| Bond & Devick Financial Network, Inc. | 0.03% | No change | 100,160 | $122K |
| Squarepoint Ops LLC | 0.00% | Add +192.6% | 99,018 | $121K |
| Quadrature Capital Ltd | 0.00% | Add +160.4% | 97,891 | $119K |
| Kotler Kevin | 0.08% | — | 93,000 | $113K |
| Algert Global LLC | 0.00% | Reduce -19.1% | 84,452 | $103K |
| ADAR1 Capital Management, LLC | 0.01% | New | 73,819 | $90K |
| Canada Pension Plan Investment Board | 0.00% | New | 61,400 | $75K |
| Federated Hermes, Inc. | 0.00% | Add +7.6% | 59,495 | $73K |
| Deeter Investments LLP | 0.01% | — | 48,025 | $59K |
| Point72 Asset Management | 0.00% | Reduce -98.9% | 46,537 | $57K |
| Simplex Trading, LLC | 0.00% | Add +253.5% | 45,912 | $56K |
| Persistent Asset Partners Ltd | 0.02% | New | 38,831 | $47K |
| Susquehanna International Group, LLP | 0.00% | Reduce -53.8% | 34,201 | $42K |
| HRT Financial LP | 0.00% | New | 32,205 | $39K |
| Engineers Gate Manager LP | 0.00% | Add +30.0% | 30,544 | $37K |
| Tudor Investment Corporation | 0.00% | No change | 29,729 | $36K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -24.5% | 26,237 | $32K |
| Blackstone Inc. | 0.00% | No change | 22,206 | $27K |
| Bronte Capital Management Pty Ltd. | 0.00% | New | 18,613 | $23K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | No change | 18,065 | $22K |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.7% | 15,824 | $19K |
| Group One Trading LLC | 0.00% | Add +405.9% | 15,790 | $19K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -68.8% | 15,425 | $19K |
| SG Americas Securities, LLC | 0.00% | Reduce -26.9% | 12,261 | $15K |
| AlphaQuest LLC | 0.00% | No change | 11,716 | $14K |
| Fiduciary Trust Co | 0.00% | No change | 11,620 | $14K |
| Barclays PLC | 0.00% | Reduce -97.1% | 10,584 | $13K |
| Rhumbline Advisers | 0.00% | No change | 2,379 | $3K |
| FMR LLC | 0.00% | Reduce -61.1% | 1,934 | $2K |
| Royal Bank of Canada | 0.00% | Reduce -92.7% | 1,185 | $2K |
| Fortitude Family Office, LLC | 0.00% | No change | 1,278 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -0.6% | 978 | $1K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -39.2% | 660 | $805 |
| BNP Paribas Financial Markets | 0.00% | Reduce -99.6% | 657 | $802 |
| Russell Investments Group, Ltd. | 0.00% | Reduce -61.5% | 542 | $661 |
| Bare Financial Services, Inc | 0.00% | New | 413 | $504 |
| MAI Capital Management | 0.00% | No change | 400 | $488 |
| SBI Securities Co., Ltd. | 0.00% | No change | 320 | $390 |
| Cornerstone Financial Management LLC | 0.00% | — | 319 | $389 |
| Wells Fargo & Company | 0.00% | No change | 50 | $61 |
| Truvestments Capital LLC | 0.00% | No change | 50 | $61 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -94.1% | 36 | $44 |
| Comerica Bank | 0.00% | Reduce -57.1% | 6 | $7 |
| Farther Finance Advisors, LLC | 0.00% | No change | 5 | $6 |
| Global Retirement Partners, LLC | 0.00% | No change | 4 | $5 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -100.0% | 1 | $1 |
| Cwm, LLC | 0.00% | Reduce -40.5% | 391 | $0 |
| Covestor Ltd | 0.00% | Reduce -2.2% | 45 | $0 |
"% of holder's portfolio" is PLRX's weight in each manager's 13F, not the share of Pliant Therapeutics Inc. the manager owns.