Prime MedicinePRME

13F holders, Q3 2024 (September 30)
116holders −6
13new positions
18sold out
5famous investors
$3.87avg. 13F price*

At the end of Q3 2024, 116 institutions reported holding Prime Medicine Inc. (PRME) in their 13F filings, down 6 from Q2 2024. 13 opened new positions and 18 sold out. The largest holders were Alphabet Inc. ($58.3M), ARK Investment Management ($21.9M) and BlackRock, Inc. ($20.4M). 5 famous investors held it, including Cathie Wood (0.2% of ARK Investment Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).

Company
Prime Medicine Inc.
CUSIP
74168J101
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 115Q1 2024Q2 2024: 122Q2 2024Q3 2024: 116Q3 2024Q4 2024: 132Q4 2024Q1 2025: 125Q1 2025Q2 2025: 121Q2 2025Q3 2025: 167Q3 2025Q4 2025: 183Q4 2025Q1 2026: 192Q1 2026Q2 2026: 187Q2 2026

Total Exit/New Position Q2 2024 → Q3 2024

InstitutionsTotal Value
New Positions13$1.6M
Exits18$2.8M

All 13F filers, Q2 2024 → Q3 2024: 3,276,495 shares bought and 3,535,742 shares sold, net −259,247 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 116 holders

Alphabet Inc. 3.16% No change 15,062,498 $58.3M
ARK Investment Management 0.20% Reduce -7.6% 5,660,719 $21.9M
BlackRock, Inc. 0.00% — 5,266,775 $20.4M
Vanguard Group Inc. 0.00% Reduce -19.6% 4,890,313 $18.9M
T. Rowe Price Investment Management, Inc. 0.01% Add +2.2% 3,807,287 $14.7M
FMR LLC 0.00% Reduce -4.7% 3,743,312 $14.5M
Sumitomo Mitsui Trust Group, Inc. 0.01% Reduce -1.5% 3,190,455 $12.3M
Amova Asset Management Americas, Inc. 0.14% Reduce -1.7% 3,182,455 $12.3M
Millennium Management 0.01% Add +65.2% 2,198,240 $8.5M
Redmile Group, LLC 0.47% No change 2,074,350 $8.0M
MWG Management Ltd. 7.68% No change 1,792,210 $6.9M
T. Rowe Price Associates Inc. 0.00% No change 1,545,961 $6.0M
Geode Capital Management, LLC 0.00% Add +4.9% 1,359,979 $5.3M
State Street Corp. 0.00% Add +3.9% 1,146,949 $4.4M
Vestal Point Capital, LP 0.33% Add +137.8% 1,070,000 $4.1M
Baker Bros. Advisors LP 0.04% No change 1,028,466 $4.0M
Deerfield Management Company, L.P. 0.06% No change 896,960 $3.5M
Farallon Capital Management, L.L.C. 0.02% No change 750,000 $2.9M
Greenwich Wealth Management LLC 0.19% Add +12.3% 733,001 $2.8M
EcoR1 Capital, LLC 0.09% No change 700,000 $2.7M
Avidity Partners Management LP 0.14% No change 694,000 $2.7M
Samsara Biocapital, LLC 0.40% No change 540,304 $2.1M
Northern Trust Corp. 0.00% Add +33.3% 524,548 $2.0M
Moore Capital Management, LP 0.06% No change 500,000 $1.9M
Bank of America Corp. 0.00% Add +13.5% 485,125 $1.9M
Charles Schwab Investment Management Inc. 0.00% Reduce -5.8% 463,977 $1.8M
Westwood Holdings Group Inc. 0.01% Add +25.4% 449,476 $1.7M
Nuveen Asset Management, LLC 0.00% No change 392,443 $1.5M
Casdin Capital, LLC 0.09% No change 367,175 $1.4M
Bollard Group LLC 0.04% No change 361,136 $1.4M
Two Sigma Investments, LP 0.00% Reduce -53.3% 318,573 $1.2M
Morgan Stanley 0.00% Add +63.3% 300,391 $1.2M
Trexquant Investment LP 0.01% Add +6.1% 242,160 $937K
Goldman Sachs Group Inc. 0.00% Add +177.4% 220,144 $852K
Wells Fargo & Company 0.00% Add +742.3% 171,468 $664K
D. E. Shaw & Co. 0.00% Add +206.9% 139,451 $540K
FIL Ltd 0.00% Reduce -6.1% 129,861 $503K
Bank of New York Mellon Corp 0.00% Reduce -23.9% 129,714 $502K
Squarepoint Ops LLC 0.00% Add +96.0% 124,369 $481K
Two Sigma Advisers, LP 0.00% Reduce -32.1% 119,900 $464K
Susquehanna International Group, LLP 0.00% Add +8.7% 115,054 $445K
Deutsche Bank AG 0.00% Reduce -75.1% 114,907 $445K
Walleye Capital LLC 0.00% New 108,374 $419K
Gsa Capital Partners LLP 0.03% New 99,060 $383K
Vestmark Advisory Solutions, Inc. 0.01% Reduce -13.0% 90,036 $348K
Barclays PLC 0.00% Add +343.4% 84,697 $328K
Chelsea Counsel Co. 0.15% Add +1.3% 78,690 $305K
Sphera Funds Management LTD. 0.05% Reduce -40.0% 76,456 $296K
Alliancebernstein L.P. 0.00% Add +8.3% 76,000 $294K
Rhumbline Advisers 0.00% Reduce -0.1% 70,047 $271K
Jane Street Group, LLC 0.00% Reduce -65.8% 57,548 $223K
Citadel Advisors 0.00% Add +300.7% 50,995 $197K
Citigroup Inc. 0.00% Add +174.5% 48,071 $186K
SG Americas Securities, LLC 0.00% New 46,982 $182K
PEAK6 Investments LLC 0.01% Add +32.4% 45,013 $174K
TD Asset Management Inc 0.00% No change 46,434 $161K
Verition Fund Management LLC 0.00% New 38,545 $149K
JPMorgan Chase & Co. 0.00% Reduce -2.1% 37,382 $145K
UBS Group AG 0.00% Add +55.4% 35,021 $136K
MetLife Investment Management, LLC 0.00% No change 34,128 $132K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +59.4% 31,127 $120K
Corebridge Financial, Inc. 0.00% Reduce -0.6% 30,325 $117K
Levin Capital Strategies, L.P. 0.01% New 30,000 $116K
Ameriprise Financial Inc. 0.00% Reduce -3.7% 28,801 $111K
Envestnet Asset Management Inc. 0.00% Add +30.9% 28,355 $110K
IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.01% Add +48.6% 28,113 $109K
Voloridge Investment Management, LLC 0.00% Reduce -40.7% 27,119 $105K
Manufacturers Life Insurance Company, The 0.00% Reduce -3.1% 23,395 $91K
Benjamin Edwards Inc. 0.00% Add +12371.0% 23,196 $90K
China Universal Asset Management Co., Ltd. 0.01% Add +63.7% 23,086 $89K
HighTower Advisors, LLC 0.00% Reduce -2.5% 21,675 $83K
Corsair Capital Management, L.P. 0.02% New 20,000 $77K
Renaissance Technologies 0.00% New 20,000 $77K
Voya Investment Management LLC 0.00% No change 19,184 $74K
Oppenheimer & Co. Inc. 0.00% Reduce -15.0% 17,871 $69K
ProShare Advisors LLC 0.00% Add +40.2% 17,811 $69K
Clarius Group, LLC 0.00% No change 16,080 $62K
Pathstone Holdings, LLC 0.00% New 14,370 $56K
Intech Investment Management LLC 0.00% New 14,102 $55K
Invesco Ltd. 0.00% Add +4.4% 14,023 $54K
Virtus Advisers, LLC 0.02% Add +1.8% 11,670 $45K
Paloma Partners Management Co 0.00% New 11,587 $45K
State Board of Administration of Florida Retirement System 0.00% No change 11,420 $44K
Acadian Asset Management LLC 0.00% New 10,886 $42K
Royal Bank of Canada 0.00% Add +74.1% 10,685 $41K
Cibc World Market Inc. 0.00% Reduce -9.8% 10,222 $40K
Brown Brothers Harriman & Co. 0.00% No change 10,065 $39K
Osaic Holdings, Inc. 0.00% Reduce -7.5% 9,901 $38K
New York State Common Retirement Fund 0.00% No change 8,434 $33K
Tower Research Capital LLC (TRC) 0.00% Add +56.1% 8,049 $31K
Legal & General Group Plc 0.00% No change 6,279 $24K
National Bank of Canada 0.00% Reduce -27.1% 4,522 $18K
California State Teachers Retirement System 0.00% No change 4,110 $16K
Ameritas Investment Partners, Inc. 0.00% No change 3,901 $15K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +21.1% 4,341 $15K
Signaturefd, LLC 0.00% Add +41.0% 1,410 $5K
Amalgamated Bank 0.00% No change 1,347 $5K
Abich Financial Wealth Management LLC 0.01% Add +307.5% 1,247 $5K
First Horizon Advisors, Inc. 0.00% Reduce -2.2% 1,109 $4K
Quadrant Capital Group LLC 0.00% New 966 $4K
GAMMA Investing LLC 0.00% Add +181.9% 654 $3K
Daiwa Securities Group Inc. 0.00% No change 398 $2K
Fairman Group, LLC 0.00% No change 500 $2K
Comerica Bank 0.00% Reduce -36.5% 315 $1K
Principal Securities, Inc. 0.00% Add +69.7% 280 $1K
Arax Advisory Partners 0.00% No change 139 $538
Nisa Investment Advisors, LLC 0.00% Reduce -98.6% 109 $422
EverSource Wealth Advisors, LLC 0.00% No change 106 $410
Sterling Capital Management LLC 0.00% — 58 $224
Russell Investments Group, Ltd. 0.00% Reduce -35.8% 52 $201
PNC Financial Services Group, Inc. 0.00% Reduce -75.4% 28 $108
Farther Finance Advisors, LLC 0.00% No change 26 $101
Federated Hermes, Inc. 0.00% New 4 $15
Lazard Asset Management LLC 0.00% Reduce -63.9% 26 $0
Cwm, LLC 0.00% Reduce -93.3% 22 $0
Covestor Ltd 0.00% Reduce -7.1% 13 $0

"% of holder's portfolio" is PRME's weight in each manager's 13F, not the share of Prime Medicine Inc. the manager owns.