Prothena Corp.PRTA

13F holders, Q3 2025 (September 30)
187holders −1
31new positions
31sold out
7famous investors
$9.76avg. 13F price*

At the end of Q3 2025, 187 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, down 1 from Q2 2025. 31 opened new positions and 31 sold out. The largest holders were FMR LLC ($77.1M), BlackRock, Inc. ($35.1M) and Vanguard Group Inc. ($20.0M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Prothena Corp. PLC
CUSIP
G72800108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 169Q1 2024Q2 2024: 160Q2 2024Q3 2024: 164Q3 2024Q4 2024: 170Q4 2024Q1 2025: 161Q1 2025Q2 2025: 188Q2 2025Q3 2025: 187Q3 2025Q4 2025: 182Q4 2025Q1 2026: 186Q1 2026Q2 2026: 187Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions31$36.5M
Exits31$12.1M

All 13F filers, Q2 2025 → Q3 2025: 9,885,047 shares bought and 8,965,710 shares sold, net +919,337 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 187 holders

FMR LLC 0.00% No change 7,901,218 $77.1M
BlackRock, Inc. 0.00% Reduce -8.7% 3,598,417 $35.1M
Vanguard Group Inc. 0.00% Reduce -5.8% 2,049,849 $20.0M
Armistice Capital, LLC 0.56% Reduce -18.4% 1,824,000 $17.8M
Rubric Capital Management LP 0.20% New 1,540,373 $15.0M
ADAR1 Capital Management, LLC 1.43% Reduce -56.5% 1,469,098 $14.3M
Palo Alto Investors LP 2.39% Add +3.9% 1,324,028 $12.9M
D. E. Shaw & Co. 0.01% Add +236.0% 1,315,418 $12.8M
Acadian Asset Management LLC 0.02% Add +21.7% 1,239,242 $12.1M
Geode Capital Management, LLC 0.00% Add +9.2% 1,019,483 $10.0M
State Street Corp. 0.00% Reduce -10.3% 901,038 $8.8M
Jacobs Levy Equity Management, Inc. 0.03% Add +26.5% 876,528 $8.6M
Dimensional Fund Advisors LP 0.00% Reduce -16.1% 806,988 $7.9M
Morgan Stanley 0.00% Reduce -16.1% 799,674 $7.8M
Citadel Advisors 0.01% Reduce -33.2% 767,105 $7.5M
JPMorgan Chase & Co. 0.00% Add +479.6% 735,765 $7.2M
Federated Hermes, Inc. 0.01% Reduce -41.3% 692,818 $6.8M
Nuveen, LLC 0.00% Add +447.1% 668,290 $6.5M
Arrowstreet Capital, Limited Partnership 0.00% New 654,294 $6.4M
Point72 Asset Management 0.01% New 646,746 $6.3M
Millennium Management 0.01% Add +264.1% 621,099 $6.1M
Jane Street Group, LLC 0.01% Add +427.7% 619,792 $6.0M
Mariner, LLC 0.01% Add +52.8% 590,897 $5.8M
Rangeley Capital, LLC 5.26% Reduce -21.6% 560,457 $5.5M
Birchview Capital, LP 4.05% Add +21.7% 549,019 $5.4M
Algert Global LLC 0.07% Add +825.9% 445,811 $4.4M
Two Sigma Investments, LP 0.01% Add +111.8% 426,605 $4.2M
UBS Group AG 0.00% Add +560.8% 400,847 $3.9M
Renaissance Technologies 0.00% Add +311.6% 371,300 $3.6M
Goldman Sachs Group Inc. 0.00% Reduce -33.1% 353,221 $3.4M
Charles Schwab Investment Management Inc. 0.00% Add +27.5% 350,821 $3.4M
Northern Trust Corp. 0.00% Add +0.0% 334,657 $3.3M
Trexquant Investment LP 0.03% Reduce -49.5% 278,979 $2.7M
Bank of America Corp. 0.00% Add +31.4% 277,096 $2.7M
Two Sigma Advisers, LP 0.01% Add +90.1% 265,700 $2.6M
Monimus Capital Management, LP 1.87% Add +25.0% 258,056 $2.5M
Qube Research & Technologies Ltd 0.00% Reduce -38.7% 254,245 $2.5M
BNP Paribas Financial Markets 0.00% Add +386.7% 228,010 $2.2M
AQR Capital Management 0.00% New 214,542 $2.1M
DCF Advisers, LLC 0.74% Add +28.3% 200,747 $2.0M
Cubist Systematic Strategies, LLC 0.03% Reduce -61.9% 190,949 $1.9M
Jump Financial, LLC 0.02% New 186,247 $1.8M
Susquehanna International Group, LLP 0.00% Add +71.2% 157,447 $1.5M
Bank of New York Mellon Corp 0.00% Add +3.7% 153,800 $1.5M
Man Group plc 0.00% Add +208.7% 131,973 $1.3M
Russell Investments Group, Ltd. 0.00% Add +32.8% 127,757 $1.2M
Squarepoint Ops LLC 0.00% Reduce -39.3% 127,033 $1.2M
Los Angeles Capital Management LLC 0.00% Add +615.0% 119,424 $1.2M
Janney Montgomery Scott LLC 0.00% New 106,898 $1.0M
Ameriprise Financial Inc. 0.00% Reduce -30.4% 105,536 $1.0M
Quantinno Capital Management LP 0.00% Add +69.7% 101,187 $988K
Barclays PLC 0.00% Reduce -15.3% 98,075 $957K
Assenagon Asset Management S.A. 0.00% New 89,704 $876K
Duncan Williams Asset Management, LLC 0.24% No change 88,339 $862K
Hennion & Walsh Asset Management, Inc. 0.03% Reduce -1.8% 84,598 $826K
T. Rowe Price Associates Inc. 0.00% Add +10.6% 78,547 $767K
American Century Companies Inc. 0.00% Add +20.5% 72,239 $705K
Pinnacle Associates Ltd. 0.01% Reduce -3.8% 71,261 $696K
Monaco Asset Management SAM 0.26% No change 70,000 $683K
Alliancebernstein L.P. 0.00% Reduce -20.5% 69,607 $679K
Creative Planning 0.00% Add +26.8% 64,140 $626K
Rhumbline Advisers 0.00% Reduce -1.5% 62,042 $606K
Franklin Resources Inc. 0.00% Add +9.1% 61,172 $597K
Caption Management, LLC 0.04% Reduce -6.3% 61,009 $595K
Focused Wealth Management, Inc 0.06% Add +77.8% 57,129 $558K
SG Americas Securities, LLC 0.00% Add +9.2% 56,719 $554K
Engineers Gate Manager LP 0.01% Add +36.9% 56,080 $547K
Balyasny Asset Management L.P. 0.00% Reduce -90.3% 55,764 $544K
Graham Capital Management, L.P. 0.03% Add +56.8% 53,393 $521K
Quinn Opportunity Partners LLC 0.04% No change 50,000 $488K
Massachusetts Financial Services Co. 0.00% Add +7.0% 47,489 $463K
Fox Run Management, L.L.C. 0.07% New 44,332 $433K
Public Employees Retirement System of Ohio 0.00% No change 42,158 $411K
Simplex Trading, LLC 0.01% Reduce -2.8% 42,044 $410K
Wells Fargo & Company 0.00% Reduce -1.9% 40,430 $395K
HSBC Holdings PLC 0.00% Reduce -18.7% 37,432 $365K
Deutsche Bank AG 0.00% Reduce -14.7% 33,773 $330K
Covestor Ltd 0.17% Reduce -25.7% 31,432 $307K
Invesco Ltd. 0.00% Reduce -15.1% 31,303 $306K
HRT Financial LP 0.00% New 31,106 $303K
ExodusPoint Capital Management, LP 0.00% Reduce -48.6% 30,254 $295K
Proficio Capital Partners LLC 0.02% New 30,136 $294K
Boothbay Fund Management, LLC 0.01% New 30,000 $293K
Arizona PSPRS Trust 0.01% New 27,700 $293K
Sandia Investment Management LP 0.89% New 29,950 $292K
RBF Capital, LLC 0.01% No change 29,200 $285K
Susquehanna Portfolio Strategies, LLC 0.00% Reduce -59.6% 28,975 $283K
STRS Ohio 0.00% Add +75.6% 28,800 $281K
Cambridge Investment Research Advisors, Inc. 0.00% Add +0.7% 27,513 $269K
Quadrature Capital Ltd 0.00% Add +14.6% 27,215 $265K
Tudor Investment Corporation 0.00% Reduce -3.3% 27,073 $264K
Alps Advisors Inc. 0.00% Reduce -11.4% 25,727 $251K
Rock Springs Capital Management LP 0.01% Reduce -94.8% 25,398 $248K
Purkiss Capital Advisors LLC 0.12% Add +1.9% 25,386 $248K
Edgewood Management LLC 0.00% No change 24,060 $235K
Virtus Investment Advisers, LLC 0.06% Add +21.0% 22,443 $219K
Raymond James Financial Inc. 0.00% Add +63.3% 22,032 $215K
Atom Investors LP 0.02% New 21,315 $208K
Handelsbanken Fonder AB 0.00% No change 20,900 $204K
Mogy Joel R Investment Counsel Inc. 0.01% No change 20,750 $203K
Prosight Management, LP 0.05% Reduce -92.5% 20,000 $195K
Foundation Wealth Management, LLC 0.13% No change 19,471 $190K
Intech Investment Management LLC 0.00% Add +5.5% 19,388 $189K
MetLife Investment Management, LLC 0.00% Reduce -23.8% 19,362 $189K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -11.2% 18,834 $184K
Ballentine Partners, LLC 0.00% New 18,310 $179K
PNC Financial Services Group, Inc. 0.00% Add +0.6% 18,137 $177K
Chicago Partners Investment Group LLC 0.00% Add +0.6% 14,841 $156K
XTX Topco Ltd 0.01% New 15,808 $154K
State Board of Administration of Florida Retirement System 0.00% No change 15,386 $150K
Corton Capital Inc. 0.34% Add +1.8% 14,208 $139K
Manufacturers Life Insurance Company, The 0.00% Reduce -8.4% 13,867 $135K
DekaBank Deutsche Girozentrale 0.00% No change 14,000 $134K
Jones Financial Companies LLLP 0.00% No change 14,000 $132K
Great Lakes Advisors, LLC 0.00% New 13,284 $130K
Thrivent Financial for Lutherans 0.00% Reduce -66.4% 12,980 $127K
Cary Street Partners Financial LLC 0.00% No change 12,500 $122K
Police & Firemen's Retirement System of New Jersey 0.00% Add +23.3% 12,464 $122K
Y-Intercept (Hong Kong) Ltd 0.00% New 12,171 $119K
Jain Global LLC 0.00% Reduce -35.5% 11,780 $115K
Oppenheimer & Co. Inc. 0.00% Reduce -37.3% 11,660 $114K
Inscription Capital, LLC 0.01% New 10,480 $102K
Royal Bank of Canada 0.00% Reduce -90.3% 10,331 $101K
Cwm, LLC 0.00% Add +650.1% 10,246 $100K
China Universal Asset Management Co., Ltd. 0.01% Reduce -12.7% 9,436 $92K
New York State Common Retirement Fund 0.00% No change 8,979 $88K
Group One Trading LLC 0.00% Reduce -78.5% 6,949 $68K
Brooklyn Investment Group 0.01% No change 11,113 $68K
Public Employees Retirement Association of Colorado 0.00% No change 6,552 $64K
Point72 (DIFC) Ltd 0.00% Reduce -75.6% 5,847 $57K
Arax Advisory Partners 0.00% New 5,384 $53K
Brown Brothers Harriman & Co. 0.00% No change 5,000 $49K
Rockefeller Capital Management L.P. 0.00% New 4,405 $43K
Signaturefd, LLC 0.00% Add +9.3% 3,670 $36K
Legal & General Group Plc 0.00% Reduce -61.4% 3,599 $35K
Citigroup Inc. 0.00% Reduce -92.7% 3,592 $35K
Ameritas Investment Partners, Inc. 0.00% Reduce -21.5% 3,428 $33K
Sterling Capital Management LLC 0.00% Add +165.6% 2,547 $25K
Farther Finance Advisors, LLC 0.00% Reduce -0.9% 2,434 $24K
California State Teachers Retirement System 0.00% Reduce -92.7% 2,415 $24K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +0.1% 2,081 $20K
Versant Capital Management, Inc 0.00% No change 2,044 $20K
HighMark Wealth Management LLC 0.01% Reduce -0.5% 2,008 $20K
Flagship Wealth Advisors, LLC 0.00% No change 1,500 $15K
Amalgamated Bank 0.00% No change 1,440 $14K
Tower Research Capital LLC (TRC) 0.00% Reduce -89.9% 1,285 $13K
Quadrant Capital Group LLC 0.00% New 1,260 $12K
GF Fund Management Co. LTD. 0.00% Reduce -16.1% 1,155 $11K
Allworth Financial LP 0.00% Add +132.5% 865 $8K
HM Payson & Co. 0.00% No change 600 $6K
Nisa Investment Advisors, LLC 0.00% Add +12.6% 592 $6K
Point72 Europe (London) LLP 0.00% New 531 $5K
GAMMA Investing LLC 0.00% Add +95.9% 386 $4K
Optiver Holding B.V. 0.00% New 352 $3K
Essential Partners LLC 0.00% New 333 $3K
US Bancorp \de 0.00% Reduce -96.5% 314 $3K
Manchester Capital Management LLC 0.00% No change 250 $2K
Osaic Holdings, Inc. 0.00% Reduce -1.6% 243 $2K
CVA Family Office, LLC 0.00% Add +212.5% 225 $2K
Daiwa Securities Group Inc. 0.00% No change 195 $2K
Evelyn Partners Investment Management LLP 0.00% No change 199 $2K
Asset Dedication, LLC 0.00% No change 184 $2K
Parallel Advisors, LLC 0.00% Reduce -69.8% 179 $2K
North Capital, Inc. 0.00% No change 159 $2K
Sittner & Nelson, LLC 0.00% No change 155 $2K
Johnson Financial Group, Inc. 0.00% New 151 $1K
Albion Financial Group 0.00% No change 125 $1K
True Wealth Design, LLC 0.00% New 103 $1K
Gould Capital, LLC 0.00% No change 100 $976
Harbor Investment Advisory, LLC 0.00% No change 100 $976
EverSource Wealth Advisors, LLC 0.00% New 90 $879
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -99.5% 71 $693
Walleye Capital LLC 0.00% Reduce -96.9% 63 $615
Northwestern Mutual Wealth Management Co. 0.00% New 50 $488
CIBC Private Wealth Group LLC 0.00% Reduce -2.0% 48 $468
Blue Trust, Inc. 0.00% No change 33 $322
SBI Securities Co., Ltd. 0.00% Reduce -97.0% 29 $283
CoreCap Advisors, LLC 0.00% No change 23 $224
Clearstead Advisors, LLC 0.00% Add +425.0% 21 $205
IFP Advisors, Inc 0.00% Add +0.0% 15 $146
Key Financial Inc 0.00% No change 12 $119
Lowe Wealth Advisors, LLC 0.00% No change 10 $98
Glen Eagle Advisors, LLC 0.00% New 10 $98
Steward Partners Investment Advisory, LLC 0.00% No change 6 $59
Larson Financial Group LLC 0.00% New 6 $59
Harbour Investments, Inc. 0.00% No change 1 $10
Truvestments Capital LLC 0.00% Reduce -98.5% 1 $9

"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.