Spruce BiosciencesSPRB

13F holders, Q1 2026 (March 31)
32holders
7new positions
9sold out
2famous investors
$65.35avg. 13F price*

At the end of Q1 2026, 32 institutions reported holding Spruce Biosciences Inc. (SPRB) in their 13F filings, unchanged from Q4 2025. 7 opened new positions and 9 sold out. The largest holders were Ikarian Capital, LLC ($7.9M), Millennium Management ($7.3M) and Citadel Advisors ($4.6M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Spruce Biosciences Inc.
CUSIP
85209E208
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q3 2025: 9Q3 2025Q4 2025: 32Q4 2025Q1 2026: 32Q1 2026Q2 2026: 64Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions7$9.0M
Exits9$7.4M

All 13F filers, Q4 2025 → Q1 2026: 143,255 shares bought and 163,775 shares sold, net −20,520 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 32 holders

Ikarian Capital, LLC 1.13% No change 121,356 $7.9M
Millennium Management 0.01% New 111,888 $7.3M
Citadel Advisors 0.00% No change 69,999 $4.6M
ADAR1 Capital Management, LLC 0.23% Add +1.0% 58,600 $3.8M
Alyeska Investment Group, L.P. 0.01% No change 51,671 $3.4M
Wellington Management Group LLP 0.00% Reduce -17.2% 48,796 $3.2M
Boothbay Fund Management, LLC 0.07% Reduce -12.2% 42,080 $2.7M
Balyasny Asset Management L.P. 0.01% No change 40,000 $2.6M
Carlyle Group Inc. 0.02% No change 38,620 $2.5M
Quinn Opportunity Partners LLC 0.09% Add +17.5% 26,810 $1.8M
ExodusPoint Capital Management, LP 0.01% Reduce -12.9% 22,000 $1.4M
Vanguard Capital Management LLC 0.00% — 18,337 $1.2M
BlackRock, Inc. 0.00% No change 16,938 $1.1M
Geode Capital Management, LLC 0.00% Add +1.2% 12,889 $843K
Squadron Capital Management LLC 0.32% Reduce -82.6% 12,200 $797K
Diadema Partners LP 0.27% New 10,000 $654K
Stempoint Capital LP 0.08% New 6,360 $416K
Vanguard Fiduciary Trust Co. 0.00% — 5,514 $360K
Goldman Sachs Group Inc. 0.00% New 5,506 $360K
State Street Corp. 0.00% Reduce -15.6% 5,400 $353K
Resolute Capital Asset Partners LLC 0.14% No change 4,000 $261K
UBS Group AG 0.00% Reduce -20.1% 3,919 $256K
Persistent Asset Partners Ltd 0.06% New 2,528 $165K
Morgan Stanley 0.00% Add +264.7% 1,415 $92K
Lion Point Capital, LP 0.39% No change 1,000 $65K
Citigroup Inc. 0.00% New 939 $61K
Vanguard Global Advisers, LLC 0.00% — 452 $30K
Sound Income Strategies, LLC 0.00% No change 200 $14K
Jones Financial Companies LLLP 0.00% Add +129.8% 193 $12K
Tower Research Capital LLC (TRC) 0.00% Add +13900.0% 140 $9K
Caldwell Sutter Capital, Inc. 0.00% No change 13 $850
Cassaday & Co Wealth Management LLC 0.00% New 2 $130

"% of holder's portfolio" is SPRB's weight in each manager's 13F, not the share of Spruce Biosciences Inc. the manager owns.