Spruce BiosciencesSPRB
13F holders, Q2 2026 (June 30)64holders +32
36new positions
4sold out
4famous investors
$54.00avg. 13F price*
At the end of Q2 2026, 64 institutions reported holding Spruce Biosciences Inc. (SPRB) in their 13F filings, up 32 from Q1 2026. 36 opened new positions and 4 sold out. The largest holders were AIGH Capital Management LLC ($13.5M), Orbimed Advisors LLC ($10.8M) and BlackRock, Inc. ($10.1M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Spruce Biosciences Inc.
- CUSIP
- 85209E208
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $42.8M |
| Exits | 4 | $4.3M |
All 13F filers, Q1 2026 → Q2 2026: 1,377,499 shares bought and 111,315 shares sold, net +1,266,184 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 64 holders
| AIGH Capital Management LLC | 1.22% | New | 250,000 | $13.5M |
| Orbimed Advisors LLC | 0.21% | New | 200,000 | $10.8M |
| BlackRock, Inc. | 0.00% | Add +1009.0% | 187,836 | $10.1M |
| Millennium Management | 0.01% | Add +43.9% | 160,981 | $8.7M |
| Ikarian Capital, LLC | 1.07% | No change | 121,356 | $6.6M |
| Vanguard Capital Management LLC | 0.00% | Add +550.8% | 119,331 | $6.4M |
| Alyeska Investment Group, L.P. | 0.01% | Add +58.1% | 81,671 | $4.4M |
| Geode Capital Management, LLC | 0.00% | Add +447.4% | 70,548 | $3.8M |
| ADAR1 Capital Management, LLC | 0.17% | Add +15.6% | 67,717 | $3.7M |
| Cable Car Capital, LP | 0.07% | New | 60,000 | $3.2M |
| Citadel Advisors | 0.00% | Reduce -25.9% | 51,905 | $2.8M |
| State Street Corp. | 0.00% | Add +834.3% | 50,450 | $2.7M |
| Boothbay Fund Management, LLC | 0.04% | No change | 42,080 | $2.3M |
| Stempoint Capital LP | 0.39% | Add +550.8% | 41,388 | $2.2M |
| Eversept Partners, LP | 0.12% | New | 40,000 | $2.2M |
| Carlyle Group Inc. | 0.02% | No change | 38,620 | $2.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +487.5% | 32,348 | $1.7M |
| Diadema Partners LP | 0.61% | Add +200.0% | 30,000 | $1.6M |
| Affinity Asset Advisors, LLC | 0.08% | New | 30,000 | $1.6M |
| Stonepine Capital Management, LLC | 1.18% | New | 28,795 | $1.6M |
| Point72 Asset Management | 0.00% | New | 28,278 | $1.5M |
| Quinn Opportunity Partners LLC | 0.07% | No change | 26,810 | $1.4M |
| UBS Group AG | 0.00% | Add +496.6% | 23,381 | $1.3M |
| ExodusPoint Capital Management, LP | 0.01% | No change | 22,000 | $1.2M |
| Northern Trust Corp. | 0.00% | New | 21,083 | $1.1M |
| Knott David M Jr | 0.57% | New | 20,000 | $1.1M |
| Rosalind Advisors, Inc. | 0.41% | New | 20,000 | $1.1M |
| Ameriprise Financial Inc. | 0.00% | New | 18,834 | $1.0M |
| Vanguard Portfolio Management LLC | 0.00% | New | 18,496 | $999K |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +233.0% | 18,361 | $991K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -69.7% | 12,138 | $655K |
| Dimensional Fund Advisors LP | 0.00% | New | 8,813 | $477K |
| Persistent Asset Partners Ltd | 0.13% | Add +203.7% | 7,677 | $415K |
| State Board of Administration of Florida Retirement System | 0.00% | New | 7,182 | $388K |
| Bank of New York Mellon Corp | 0.00% | New | 6,779 | $366K |
| Charles Schwab Investment Management Inc. | 0.00% | New | 5,896 | $318K |
| Renaissance Technologies | 0.00% | New | 4,700 | $254K |
| Morgan Stanley | 0.00% | Add +211.7% | 4,411 | $238K |
| Pale Fire Capital SE | 0.01% | New | 3,818 | $206K |
| Rhumbline Advisers | 0.00% | New | 3,519 | $190K |
| SkyView Investment Advisors, LLC | 0.13% | New | 3,000 | $162K |
| Deutsche Bank AG | 0.00% | New | 2,652 | $143K |
| Wells Fargo & Company | 0.00% | New | 2,329 | $126K |
| New York State Common Retirement Fund | 0.00% | New | 1,900 | $103K |
| Citigroup Inc. | 0.00% | Add +34.7% | 1,265 | $68K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 1,252 | $68K |
| JPMorgan Chase & Co. | 0.00% | New | 1,127 | $63K |
| Lion Point Capital, LP | 0.26% | No change | 1,000 | $54K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 864 | $47K |
| Barclays PLC | 0.00% | New | 674 | $36K |
| BNP Paribas Financial Markets | 0.00% | New | 453 | $24K |
| Vanguard Global Advisers, LLC | 0.00% | No change | 452 | $24K |
| FMR LLC | 0.00% | New | 343 | $19K |
| Legal & General Group Plc | 0.00% | New | 264 | $14K |
| Ameritas Investment Partners, Inc. | 0.00% | New | 247 | $13K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +75.7% | 246 | $13K |
| Russell Investments Group, Ltd. | 0.00% | New | 217 | $12K |
| SBI Securities Co., Ltd. | 0.00% | New | 201 | $11K |
| Royal Bank of Canada | 0.00% | New | 166 | $8K |
| Sterling Capital Management LLC | 0.00% | New | 43 | $2K |
| Jones Financial Companies LLLP | 0.00% | Reduce -84.5% | 30 | $2K |
| Caldwell Sutter Capital, Inc. | 0.00% | No change | 13 | $702 |
| Friedenthal Financial | 0.00% | New | 7 | $378 |
| Cassaday & Co Wealth Management LLC | 0.00% | No change | 2 | $108 |
"% of holder's portfolio" is SPRB's weight in each manager's 13F, not the share of Spruce Biosciences Inc. the manager owns.