Spero TherapeuticsSPRO
13F holders, Q2 2024 (June 30)At the end of Q2 2024, 48 institutions reported holding Spero Therapeutics Inc. (SPRO) in their 13F filings, down 6 from Q1 2024. 5 opened new positions and 11 sold out. The largest holders were Anson Funds Management LP ($4.9M), Vanguard Group Inc. ($2.3M) and Acadian Asset Management LLC ($1.4M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Spero Therapeutics Inc.
- CUSIP
- 84833T103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2024 → Q2 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 5 | $529K |
| Exits | 11 | $535K |
All 13F filers, Q1 2024 → Q2 2024: 989,864 shares bought and 869,897 shares sold, net +119,967 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 48 holders
| Anson Funds Management LP | 0.75% | No change | 3,750,450 | $4.9M |
| Vanguard Group Inc. | 0.00% | Add +7.1% | 1,770,525 | $2.3M |
| Acadian Asset Management LLC | 0.00% | Add +40.5% | 1,071,860 | $1.4M |
| Renaissance Technologies | 0.00% | Add +14.2% | 975,952 | $1.3M |
| ADAR1 Capital Management, LLC | 0.24% | Reduce -0.9% | 918,929 | $1.2M |
| Alphabet Inc. | 0.06% | No change | 889,979 | $1.2M |
| Murchinson Ltd. | 0.26% | No change | 873,910 | $1.1M |
| Atlas Venture Life Science Advisors, LLC | 0.07% | Reduce -11.9% | 535,336 | $696K |
| Geode Capital Management, LLC | 0.00% | Add +4.8% | 492,187 | $640K |
| BlackRock Inc. | 0.00% | Add +1.4% | 483,402 | $628K |
| Novo Holdings A/S | 0.03% | No change | 468,902 | $610K |
| AWM Investment Company, Inc. | 0.06% | No change | 333,400 | $433K |
| Citadel Advisors | 0.00% | New | 312,034 | $406K |
| Bridgeway Capital Management, LLC | 0.01% | No change | 184,800 | $240K |
| State Street Corp. | 0.00% | No change | 130,511 | $170K |
| DAFNA Capital Management LLC | 0.04% | No change | 125,000 | $163K |
| Northern Trust Corp. | 0.00% | Reduce -2.0% | 112,303 | $146K |
| Millennium Management | 0.00% | Reduce -33.4% | 98,518 | $128K |
| Man Group plc | 0.00% | Reduce -65.7% | 73,469 | $96K |
| Two Sigma Securities, LLC | 0.00% | New | 67,728 | $88K |
| Mackenzie Financial Corp. | 0.00% | Add +15.1% | 32,729 | $43K |
| DLK Investment Management, LLC | 0.02% | No change | 31,355 | $41K |
| Charles Schwab Investment Management Inc. | 0.00% | No change | 28,565 | $37K |
| Shay Capital LLC | 0.01% | Reduce -91.9% | 25,000 | $33K |
| Susquehanna International Group, LLP | 0.00% | New | 23,073 | $30K |
| Three Seasons Wealth, LLC | 0.01% | No change | 15,000 | $20K |
| Dimensional Fund Advisors LP | 0.00% | No change | 10,003 | $13K |
| Texas Yale Capital Corp. | 0.00% | No change | 10,000 | $13K |
| Morgan Stanley | 0.00% | Reduce -11.8% | 6,971 | $9K |
| Russell Investments Group, Ltd. | 0.00% | No change | 6,400 | $8K |
| Bank of America Corp. | 0.00% | Add +7.0% | 5,558 | $7K |
| FMR LLC | 0.00% | Add +20.9% | 2,889 | $4K |
| WR Wealth Planners, LLC | 0.00% | No change | 2,600 | $3K |
| Royal Bank of Canada | 0.00% | New | 1,959 | $3K |
| Cullen/Frost Bankers, Inc. | 0.00% | New | 2,000 | $3K |
| Wells Fargo & Company | 0.00% | Add +85.2% | 1,000 | $1K |
| Allworth Financial LP | 0.00% | No change | 600 | $840 |
| Rhumbline Advisers | 0.00% | No change | 458 | $595 |
| UBS Group AG | 0.00% | Reduce -94.2% | 331 | $430 |
| Osaic Holdings, Inc. | 0.00% | Add +527.7% | 295 | $384 |
| Tower Research Capital LLC (TRC) | 0.00% | Add +27.8% | 276 | $359 |
| JPMorgan Chase & Co. | 0.00% | No change | 236 | $307 |
| CoreCap Advisors, LLC | 0.00% | Add +35.2% | 192 | $250 |
| US Bancorp \de | 0.00% | No change | 151 | $196 |
| NewEdge Advisors, LLC | 0.00% | No change | 100 | $130 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 30 | $39 |
| BNP Paribas Financial Markets | 0.00% | No change | 12 | $16 |
| Qube Research & Technologies Ltd | 0.00% | No change | 1 | $1 |
"% of holder's portfolio" is SPRO's weight in each manager's 13F, not the share of Spero Therapeutics Inc. the manager owns.