Ars PharmaceuticalsSPRY
13F holders, Q4 2025 (December 31)191holders +3
31new positions
33sold out
5famous investors
$11.65avg. 13F price*
At the end of Q4 2025, 191 institutions reported holding Ars Pharmaceuticals Inc. (SPRY) in their 13F filings, up 3 from Q3 2025. 31 opened new positions and 33 sold out. The largest holders were Ra Capital Management, L.P. ($126.5M), Orbimed Advisors LLC ($96.6M) and Deerfield Management Company, L.P. ($87.4M). 5 famous investors held it, including Dan Loeb (0.1% of Third Point's portfolio), Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Ars Pharmaceuticals Inc.
- CUSIP
- 82835W108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $107.3M |
| Exits | 33 | $43.3M |
All 13F filers, Q3 2025 → Q4 2025: 15,942,357 shares bought and 10,934,173 shares sold, net +5,008,184 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 191 holders
| Ra Capital Management, L.P. | 1.30% | No change | 10,860,977 | $126.5M |
| Orbimed Advisors LLC | 1.98% | No change | 8,288,510 | $96.6M |
| Deerfield Management Company, L.P. | 1.28% | No change | 7,503,812 | $87.4M |
| Rubric Capital Management LP | 0.86% | Add +37.8% | 6,200,000 | $72.2M |
| BlackRock, Inc. | 0.00% | Add +5.3% | 5,085,317 | $59.2M |
| SR One Capital Management, LP | 6.62% | No change | 4,012,903 | $46.8M |
| Aberdeen Group plc | 0.06% | Add +14.8% | 3,556,049 | $41.4M |
| Vanguard Group Inc. | 0.00% | Add +0.3% | 3,509,174 | $40.9M |
| State Street Corp. | 0.00% | Add +11.3% | 3,223,581 | $37.6M |
| Millennium Management | 0.03% | New | 3,168,406 | $36.9M |
| Franklin Resources Inc. | 0.01% | Add +6.0% | 2,543,097 | $29.6M |
| UBS Group AG | 0.01% | Add +235.0% | 2,210,866 | $25.8M |
| Tyro Capital Management LLC | 7.23% | New | 1,994,852 | $23.2M |
| Citadel Advisors | 0.02% | Add +23.2% | 1,954,472 | $22.8M |
| Casdin Capital, LLC | 1.16% | No change | 1,600,000 | $18.6M |
| Geode Capital Management, LLC | 0.00% | Add +3.1% | 1,552,870 | $18.1M |
| Southpoint Capital Advisors LP | 0.41% | No change | 1,500,000 | $17.5M |
| Janney Montgomery Scott LLC | 0.03% | Add +6.2% | 1,287,832 | $15.0M |
| Baron Capital (BAMCO) | 0.04% | No change | 1,268,532 | $14.8M |
| Pavaki Capital Management LLC | 9.53% | — | 1,172,000 | $13.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -38.8% | 812,036 | $9.5M |
| FIL Ltd | 0.01% | New | 810,073 | $9.4M |
| Levin Capital Strategies, L.P. | 0.76% | Reduce -2.2% | 747,506 | $8.7M |
| Nextech Invest Ltd. | 0.74% | No change | 660,703 | $7.7M |
| Bank of Montreal | 0.00% | New | 643,407 | $7.5M |
| CenterBook Partners LP | 0.32% | Add +10.9% | 568,361 | $6.6M |
| Raymond James Financial Inc. | 0.00% | Reduce -25.2% | 566,056 | $6.6M |
| General American Investors Co. Inc. | 0.41% | New | 559,959 | $6.5M |
| Third Point | 0.09% | New | 556,237 | $6.5M |
| Morgan Stanley | 0.00% | Reduce -21.1% | 552,364 | $6.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.8% | 550,932 | $6.4M |
| Northern Trust Corp. | 0.00% | Reduce -2.0% | 521,009 | $6.1M |
| Bank of America Corp. | 0.00% | Add +77.2% | 482,084 | $5.6M |
| American Century Companies Inc. | 0.00% | New | 455,766 | $5.3M |
| Alyeska Investment Group, L.P. | 0.01% | Add +7.4% | 418,883 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Add +1089.7% | 417,090 | $4.9M |
| FMR LLC | 0.00% | Reduce -46.3% | 398,959 | $4.6M |
| Lisanti Capital Growth, LLC | 1.09% | Add +87.8% | 396,509 | $4.6M |
| ADAR1 Capital Management, LLC | 0.32% | Add +524.0% | 369,569 | $4.3M |
| Empire Life Investments Inc. | 0.23% | Reduce -0.9% | 352,602 | $4.1M |
| Investment Management Associates Inc. | 1.01% | New | 311,503 | $3.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -9.2% | 304,445 | $3.5M |
| Creek Drive Management Group LLC | 2.56% | — | 295,863 | $3.4M |
| Eversept Partners, LP | 0.16% | Reduce -74.2% | 251,593 | $2.9M |
| Steward Partners Investment Advisory, LLC | 0.01% | Add +47.5% | 216,296 | $2.5M |
| Royce & Associates LP | 0.02% | New | 207,051 | $2.4M |
| FAS Wealth Partners, Inc. | 0.15% | Add +0.9% | 202,407 | $2.4M |
| Boothbay Fund Management, LLC | 0.06% | New | 201,474 | $2.3M |
| Barclays PLC | 0.00% | Reduce -14.1% | 196,387 | $2.3M |
| DAFNA Capital Management LLC | 0.52% | Add +35.3% | 190,065 | $2.2M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -1.1% | 176,122 | $2.1M |
| Wexford Capital LP | 0.50% | Reduce -1.7% | 165,313 | $1.9M |
| Bank of New York Mellon Corp | 0.00% | Add +5.4% | 163,006 | $1.9M |
| Quinn Opportunity Partners LLC | 0.08% | Add +24.0% | 155,000 | $1.8M |
| Woodline Partners LP | 0.01% | No change | 150,936 | $1.8M |
| Trexquant Investment LP | 0.02% | Reduce -76.2% | 150,100 | $1.7M |
| Nuveen, LLC | 0.00% | No change | 149,597 | $1.7M |
| Knights of Columbus Asset Advisors LLC | 0.09% | Reduce -2.8% | 130,729 | $1.5M |
| Rafferty Asset Management, LLC | 0.00% | Reduce -5.6% | 115,564 | $1.3M |
| Principal Financial Group Inc. | 0.00% | Add +46.7% | 112,766 | $1.3M |
| Legato Capital Management LLC | 0.11% | Add +176.8% | 109,095 | $1.3M |
| Swiss National Bank | 0.00% | Add +27.2% | 107,200 | $1.2M |
| Sit Investment Associates Inc. | 0.02% | Add +24.6% | 92,875 | $1.1M |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 87,161 | $1.0M |
| Valley Forge Investment Consultants Inc. Adv | 0.28% | No change | 83,225 | $970K |
| Alps Advisors Inc. | 0.01% | Add +63.6% | 81,168 | $946K |
| Marshall Wace, LLP | 0.00% | Reduce -59.9% | 79,214 | $923K |
| SG Americas Securities, LLC | 0.00% | Add +654.1% | 76,203 | $888K |
| AssuredPartners Investment Advisors, LLC | 0.13% | Add +31.1% | 75,779 | $883K |
| Sei Investments Co. | 0.00% | Add +55.5% | 74,807 | $872K |
| Wells Fargo & Company | 0.00% | Add +0.6% | 74,256 | $865K |
| Rhumbline Advisers | 0.00% | Reduce -9.7% | 73,293 | $854K |
| HRT Financial LP | 0.00% | New | 68,645 | $799K |
| Alliancebernstein L.P. | 0.00% | Reduce -97.7% | 60,120 | $700K |
| Legal & General Group Plc | 0.00% | Add +5.7% | 58,368 | $680K |
| Matisse Capital | 0.29% | Reduce -3.9% | 55,561 | $647K |
| American Assets Inc. | 0.20% | No change | 55,000 | $641K |
| California State Teachers Retirement System | 0.00% | Add +21.9% | 54,098 | $630K |
| Coastal Bridge Advisors, LLC | 0.05% | Reduce -41.3% | 53,830 | $627K |
| Quantinno Capital Management LP | 0.00% | Add +31.2% | 53,113 | $619K |
| Permanent Capital Management, LP | 0.12% | Reduce -1.9% | 52,306 | $609K |
| Schulhoff & Co. Inc. | 0.25% | Add +17.6% | 51,150 | $596K |
| Deutsche Bank AG | 0.00% | Add +16.1% | 48,727 | $568K |
| Los Angeles Capital Management LLC | 0.00% | New | 65,746 | $567K |
| Profund Advisors LLC | 0.02% | Add +62.6% | 42,808 | $499K |
| Fox Run Management, L.L.C. | 0.07% | New | 38,587 | $450K |
| Invesco Ltd. | 0.00% | Reduce -7.2% | 37,230 | $434K |
| XTX Topco Ltd | 0.01% | Reduce -74.1% | 37,201 | $433K |
| Aquatic Capital Management LLC | 0.01% | Reduce -65.9% | 36,037 | $420K |
| MetLife Investment Management, LLC | 0.00% | No change | 34,338 | $400K |
| Voya Investment Management LLC | 0.00% | Reduce -70.3% | 34,128 | $398K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.3% | 34,100 | $397K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 33,788 | $394K |
| Diker Management LLC | 0.30% | Reduce -23.0% | 33,508 | $390K |
| AlphaQuest LLC | 0.02% | Reduce -28.0% | 32,970 | $384K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -1.3% | 32,058 | $373K |
| Private Advisor Group, LLC | 0.00% | Add +52.9% | 31,460 | $367K |
| Cresset Asset Management, LLC | 0.00% | No change | 30,152 | $351K |
| Sectoral Asset Management Inc. | 0.28% | Reduce -63.6% | 29,803 | $347K |
| Canada Pension Plan Investment Board | 0.00% | New | 29,600 | $345K |
| Freestone Grove Partners LP | 0.00% | Reduce -81.6% | 28,003 | $326K |
| HighTower Advisors, LLC | 0.00% | Add +0.8% | 26,529 | $309K |
| D. E. Shaw & Co. | 0.00% | Reduce -22.5% | 26,527 | $309K |
| Belpointe Asset Management LLC | 0.01% | Add +35.0% | 25,468 | $297K |
| Creative Planning | 0.00% | Reduce -6.8% | 25,328 | $295K |
| Nano Cap New Millennium Growth Fund L P | 0.25% | — | 25,000 | $291K |
| Letko, Brosseau & Associates Inc. | 0.00% | No change | 24,700 | $288K |
| Wealthspire Advisors, LLC | 0.00% | New | 23,650 | $276K |
| LPL Financial LLC | 0.00% | Reduce -0.7% | 22,916 | $267K |
| Intech Investment Management LLC | 0.00% | Reduce -28.2% | 22,626 | $264K |
| VARCOV Co. | 0.10% | — | 22,300 | $260K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.00% | New | 21,614 | $252K |
| Janus Henderson Group PLC | 0.00% | No change | 21,600 | $252K |
| Nisa Investment Advisors, LLC | 0.00% | Add +229.8% | 20,620 | $240K |
| Everstar Asset Management, LLC | 0.12% | No change | 20,000 | $233K |
| Citigroup Inc. | 0.00% | Add +115.4% | 18,564 | $216K |
| Oppenheimer & Co. Inc. | 0.00% | Add +42.7% | 17,858 | $208K |
| New York State Common Retirement Fund | 0.00% | No change | 17,707 | $206K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -7.0% | 16,107 | $188K |
| Arizona State Retirement System | 0.00% | Add +17.6% | 15,372 | $179K |
| Cetera Investment Advisers | 0.00% | New | 15,340 | $179K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 15,148 | $176K |
| ProShare Advisors LLC | 0.00% | Add +11.3% | 15,139 | $176K |
| Foster & Motley Inc. | 0.01% | No change | 14,780 | $172K |
| Lazard Asset Management LLC | 0.00% | New | 14,347 | $167K |
| Amica Mutual Insurance Co. | 0.01% | No change | 14,350 | $167K |
| Sherbrooke Park Advisers LLC | 0.40% | New | 13,139 | $153K |
| Tannin Capital LLC | 0.14% | — | 13,066 | $152K |
| Jones Financial Companies LLLP | 0.00% | Add +731.5% | 12,140 | $141K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 11,662 | $136K |
| KLP Kapitalforvaltning As | 0.00% | No change | 11,600 | $135K |
| Blair William & Co. | 0.00% | New | 11,600 | $135K |
| Cygnus Capital Advisors, LLC | 0.09% | — | 10,556 | $123K |
| Pictet Asset Management Holding SA | 0.00% | Reduce -94.5% | 10,362 | $121K |
| K2 Principal Fund, L.P. | 0.04% | Reduce -98.4% | 10,200 | $119K |
| Wealth Architects, LLC | 0.01% | New | 10,000 | $117K |
| Group One Trading LLC | 0.00% | Add +23.6% | 9,517 | $111K |
| CX Institutional | 0.00% | Reduce -2.2% | 8,990 | $105K |
| BNP Paribas Financial Markets | 0.00% | Reduce -48.9% | 6,407 | $75K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -12.9% | 5,805 | $68K |
| Osterweis Capital Management Inc. | 0.00% | New | 5,610 | $65K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -12.7% | 4,888 | $57K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +25.7% | 4,803 | $56K |
| Royal Bank of Canada | 0.00% | Reduce -87.7% | 4,684 | $54K |
| Osaic Holdings, Inc. | 0.00% | Reduce -12.2% | 3,626 | $42K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -93.0% | 3,470 | $40K |
| Signaturefd, LLC | 0.00% | No change | 2,812 | $33K |
| Torren Management, LLC | 0.02% | — | 2,762 | $32K |
| Versant Capital Management, Inc | 0.00% | Add +91.7% | 2,574 | $30K |
| Bernard Wealth Management Corp. | 0.01% | No change | 2,520 | $29K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 2,160 | $25K |
| Caz Investments LP | 0.04% | No change | 2,000 | $23K |
| Smartleaf Asset Management LLC | 0.00% | Add +253.6% | 1,952 | $23K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.7% | 1,942 | $23K |
| Rockefeller Capital Management L.P. | 0.00% | Add +89.4% | 1,894 | $22K |
| Amalgamated Bank | 0.00% | Add +10.2% | 1,853 | $22K |
| US Bancorp \de | 0.00% | Reduce -6.3% | 1,475 | $17K |
| Capital Analysts, LLC | 0.00% | No change | 1,300 | $15K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -26.0% | 1,139 | $13K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -85.9% | 1,049 | $12K |
| Heritage Wealth Advisors | 0.00% | No change | 1,000 | $12K |
| Eastern Bank | 0.00% | New | 750 | $9K |
| SBI Securities Co., Ltd. | 0.00% | Add +7.3% | 749 | $9K |
| Allworth Financial LP | 0.00% | Reduce -6.7% | 743 | $9K |
| Golden State Wealth Management, LLC | 0.00% | No change | 484 | $6K |
| Avion Wealth | 0.00% | No change | 500 | $5K |
| Sterling Capital Management LLC | 0.00% | Add +181.1% | 402 | $5K |
| Brown, Lisle/Cummings, Inc. | 0.00% | No change | 400 | $5K |
| Spire Wealth Management | 0.00% | No change | 400 | $5K |
| Arax Advisory Partners | 0.00% | Add +188.3% | 369 | $4K |
| Hilton Head Capital Partners, LLC | 0.00% | — | 365 | $4K |
| Quadrant Capital Group LLC | 0.00% | No change | 347 | $4K |
| Daiwa Securities Group Inc. | 0.00% | No change | 367 | $4K |
| Optiver Holding B.V. | 0.00% | Reduce -27.0% | 260 | $3K |
| Bessemer Group Inc. | 0.00% | No change | 235 | $3K |
| Quarry LP | 0.00% | New | 250 | $3K |
| Comerica Bank | 0.00% | Add +83.9% | 217 | $3K |
| Key Financial Inc | 0.00% | New | 200 | $2K |
| Tidemark, LLC | 0.00% | No change | 169 | $2K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 153 | $2K |
| GAMMA Investing LLC | 0.00% | Reduce -39.7% | 108 | $1K |
| Tripletail Wealth Management, LLC | 0.00% | Reduce -77.8% | 100 | $1K |
| Cwm, LLC | 0.00% | Reduce -97.6% | 62 | $1K |
| Larson Financial Group LLC | 0.00% | Add +1975.0% | 83 | $967 |
| PNC Financial Services Group, Inc. | 0.00% | New | 36 | $419 |
| Strategic Wealth Partners, Ltd. | 0.00% | New | 20 | $233 |
| Rothschild Investment LLC | 0.00% | Reduce -54.3% | 16 | $186 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 9 | $105 |
| Essential Partners LLC | 0.00% | New | 4 | $47 |
| Lanark Financial, Inc. | 0.00% | No change | 1 | $11 |
| Covestor Ltd | 0.00% | Reduce -12.5% | 7 | $0 |
"% of holder's portfolio" is SPRY's weight in each manager's 13F, not the share of Ars Pharmaceuticals Inc. the manager owns.