Trevi TherapeuticsTRVI
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 184 institutions reported holding Trevi Therapeutics Inc. (TRVI) in their 13F filings, up 20 from Q3 2025. 29 opened new positions and 14 sold out. The largest holders were NEA Management Company, LLC ($165.5M), Frazier Life Sciences Management, L.P. ($128.4M) and BlackRock, Inc. ($126.8M). 7 famous investors held it, including Andreas Halvorsen (0.1% of Viking Global Investors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Trevi Therapeutics Inc.
- CUSIP
- 89532M101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $74.9M |
| Exits | 14 | $6.6M |
All 13F filers, Q3 2025 → Q4 2025: 18,284,485 shares bought and 17,753,463 shares sold, net +531,022 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 184 holders
| NEA Management Company, LLC | 8.44% | No change | 13,222,228 | $165.5M |
| Frazier Life Sciences Management, L.P. | 3.46% | No change | 10,259,409 | $128.4M |
| BlackRock, Inc. | 0.00% | Add +2.3% | 10,126,183 | $126.8M |
| FMR LLC | 0.00% | Add +97.0% | 6,500,009 | $81.4M |
| Vanguard Group Inc. | 0.00% | Add +10.4% | 6,434,655 | $80.6M |
| Vivo Capital, LLC | 4.12% | No change | 5,094,668 | $63.8M |
| Marshall Wace, LLP | 0.06% | Reduce -5.4% | 4,580,548 | $57.3M |
| Rubric Capital Management LP | 0.56% | Reduce -55.9% | 3,766,749 | $47.2M |
| Wellington Management Group LLP | 0.01% | Add +4.6% | 3,403,990 | $42.6M |
| MPM Bioimpact LLC | 4.71% | Reduce -3.5% | 3,287,087 | $41.2M |
| Viking Global Investors | 0.11% | Reduce -37.6% | 3,198,644 | $40.0M |
| Orbimed Advisors LLC | 0.82% | Reduce -3.6% | 3,190,700 | $39.9M |
| Alliancebernstein L.P. | 0.01% | Reduce -28.2% | 3,082,986 | $38.6M |
| Octagon Capital Advisors LP | 4.41% | No change | 2,815,000 | $35.2M |
| Eventide Asset Management, LLC | 0.51% | Add +89.8% | 2,622,306 | $32.8M |
| State Street Corp. | 0.00% | Add +9.7% | 2,435,000 | $30.5M |
| Geode Capital Management, LLC | 0.00% | Add +8.6% | 2,412,885 | $30.2M |
| Siren, L.L.C. | 0.85% | Reduce -9.8% | 2,286,867 | $28.6M |
| Affinity Asset Advisors, LLC | 2.00% | Reduce -23.2% | 2,150,172 | $26.9M |
| Acorn Capital Advisors, LLC | 9.10% | No change | 2,144,844 | $26.9M |
| Artia Global Partners LP | 4.05% | Add +0.7% | 2,013,602 | $25.2M |
| Emerald Advisers, LLC | 0.73% | New | 1,892,276 | $23.7M |
| Raymond James Financial Inc. | 0.01% | Add +25.2% | 1,766,963 | $22.1M |
| Logos Global Management LP | 1.29% | Reduce -29.6% | 1,550,000 | $19.4M |
| Pictet Asset Management Holding SA | 0.02% | Add +13507.0% | 1,532,013 | $19.2M |
| Emerald Mutual Fund Advisers Trust | 0.78% | New | 1,272,373 | $15.9M |
| Pivotal bioVenture Partners Investment Advisor LLC | 6.08% | No change | 1,256,782 | $15.7M |
| Frontier Capital Management Co. LLC | 0.15% | New | 1,108,468 | $13.9M |
| Bank of America Corp. | 0.00% | Reduce -40.4% | 1,094,851 | $13.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +34.2% | 1,056,891 | $13.2M |
| Flputnam Investment Management Co. | 0.19% | Add +0.5% | 1,053,427 | $13.2M |
| Morgan Stanley | 0.00% | Reduce -75.6% | 1,050,296 | $13.1M |
| Woodline Partners LP | 0.05% | Add +897.5% | 1,000,282 | $12.5M |
| Point72 Asset Management | 0.02% | Add +6.2% | 1,000,000 | $12.5M |
| Nan Fung Trinity (hk) Ltd. | 0.91% | Add +924.2% | 917,450 | $11.5M |
| Soleus Capital Management, L.P. | 0.48% | Add +3500.0% | 900,000 | $11.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.8% | 836,800 | $10.5M |
| Susquehanna International Group, LLP | 0.01% | Reduce -48.4% | 825,548 | $10.3M |
| Northern Trust Corp. | 0.00% | Add +3.4% | 761,966 | $9.5M |
| Panagora Asset Management Inc. | 0.03% | Add +21.5% | 693,001 | $8.7M |
| Sphera Funds Management LTD. | 1.57% | Reduce -7.0% | 598,534 | $7.5M |
| Barclays PLC | 0.00% | Add +168.7% | 582,653 | $7.3M |
| Millennium Management | 0.01% | Reduce -21.6% | 570,226 | $7.1M |
| Prudential Financial Inc. | 0.01% | Reduce -8.9% | 549,219 | $6.9M |
| Informed Momentum Co LLC | 0.75% | Reduce -1.5% | 541,242 | $6.8M |
| Silverarc Capital Management, LLC | 0.98% | Reduce -8.1% | 541,240 | $6.8M |
| Burkehill Global Management, LP | 0.45% | No change | 525,000 | $6.6M |
| Peregrine Capital Management LLC | 0.19% | Reduce -18.2% | 507,685 | $6.4M |
| Invesco Ltd. | 0.00% | Add +3.3% | 498,926 | $6.2M |
| J. Goldman & Co LP | 0.22% | Reduce -44.0% | 444,357 | $5.6M |
| KVP Capital Advisors, LP | 5.35% | — | 414,000 | $5.2M |
| Stempoint Capital LP | 0.86% | Add +13.9% | 399,557 | $5.0M |
| Opaleye Management Inc. | 0.57% | Reduce -11.5% | 345,100 | $4.3M |
| Ameriprise Financial Inc. | 0.00% | New | 324,172 | $4.1M |
| UBS Group AG | 0.00% | Reduce -8.0% | 274,628 | $3.4M |
| Bank of New York Mellon Corp | 0.00% | Add +15.1% | 260,587 | $3.3M |
| F/m Investments LLC | 0.11% | New | 241,483 | $3.0M |
| Voya Investment Management LLC | 0.00% | Add +1390.2% | 226,215 | $2.8M |
| Velan Capital Investment Management LP | 1.49% | No change | 205,000 | $2.6M |
| Nuveen, LLC | 0.00% | No change | 183,329 | $2.3M |
| Balyasny Asset Management L.P. | 0.00% | Reduce -72.1% | 174,641 | $2.2M |
| Swiss National Bank | 0.00% | Add +4.0% | 168,200 | $2.1M |
| Fred Alger Management, LLC | 0.01% | Reduce -17.3% | 157,980 | $2.0M |
| Citadel Advisors | 0.00% | Add +49.1% | 152,855 | $1.9M |
| Superstring Capital Management LP | 0.99% | New | 148,292 | $1.9M |
| Sei Investments Co. | 0.00% | Add +72.4% | 147,941 | $1.9M |
| D. E. Shaw & Co. | 0.00% | New | 141,312 | $1.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +20.8% | 140,733 | $1.8M |
| BIT Capital GmbH | 0.07% | Add +1829.1% | 130,000 | $1.6M |
| HRT Financial LP | 0.00% | New | 125,104 | $1.6M |
| SG Americas Securities, LLC | 0.00% | Add +93.0% | 124,562 | $1.6M |
| Citigroup Inc. | 0.00% | Add +358.9% | 123,498 | $1.5M |
| State of Wisconsin Investment Board | 0.00% | Reduce -2.2% | 120,566 | $1.5M |
| HighVista Strategies LLC | 0.34% | New | 106,159 | $1.3M |
| Rhumbline Advisers | 0.00% | Reduce -7.9% | 105,922 | $1.3M |
| Wells Fargo & Company | 0.00% | Add +81.9% | 101,279 | $1.3M |
| Oppenheimer & Co. Inc. | 0.02% | Add +2.1% | 100,698 | $1.3M |
| Rosalind Advisors, Inc. | 0.46% | No change | 100,000 | $1.3M |
| LMR Partners LLP | 0.02% | No change | 100,000 | $1.3M |
| Diadema Partners LP | 0.72% | Add +13.2% | 97,184 | $1.2M |
| Erste Asset Management GmbH | 0.01% | New | 90,000 | $1.2M |
| Sectoral Asset Management Inc. | 0.85% | Reduce -20.5% | 84,255 | $1.1M |
| XTX Topco Ltd | 0.03% | New | 83,818 | $1.0M |
| California State Teachers Retirement System | 0.00% | Add +2.6% | 83,788 | $1.0M |
| Two Sigma Investments, LP | 0.00% | Reduce -30.2% | 83,755 | $1.0M |
| Comerica Bank | 0.00% | Add +19481.8% | 83,027 | $1.0M |
| Wexford Capital LP | 0.26% | New | 82,034 | $1.0M |
| Legal & General Group Plc | 0.00% | Reduce -0.4% | 81,673 | $1.0M |
| PFS Partners, LLC | 0.45% | No change | 79,000 | $989K |
| MAI Capital Management | 0.01% | Reduce -21.0% | 77,769 | $974K |
| Hudson Bay Capital Management LP | 0.01% | New | 75,000 | $939K |
| Campbell & CO Investment Adviser LLC | 0.04% | Add +185.7% | 71,097 | $890K |
| Deutsche Bank AG | 0.00% | Add +37.2% | 70,833 | $887K |
| Tudor Investment Corporation | 0.00% | New | 68,481 | $857K |
| WealthTrust Axiom LLC | 0.20% | No change | 61,500 | $770K |
| Optimize Financial Inc. | 0.39% | Add +1.5% | 61,483 | $770K |
| JPMorgan Chase & Co. | 0.00% | Add +1.1% | 59,475 | $745K |
| Russell Investments Group, Ltd. | 0.00% | Add +5.3% | 59,444 | $744K |
| Kennedy Capital Management LLC | 0.01% | Add +2.4% | 56,269 | $704K |
| LPL Financial LLC | 0.00% | Add +30.9% | 52,960 | $663K |
"% of holder's portfolio" is TRVI's weight in each manager's 13F, not the share of Trevi Therapeutics Inc. the manager owns.