Vertex PharmaceuticalsVRTX
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 1,561 institutions reported holding Vertex Pharmaceuticals Inc. (VRTX) in their 13F filings, up 13 from Q3 2024. 97 opened new positions and 153 sold out. The largest holders were Capital World Investors ($11.4B), Vanguard Group Inc. ($9.4B) and BlackRock, Inc. ($8.8B). 11 famous investors held it, including Jim Simons / Peter Brown (0.8% of Renaissance Technologies's portfolio), Cliff Asness (0.1% of AQR Capital Management's portfolio) and David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio).
- Company
- Vertex Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 92532F100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 97 | $1.5B |
| Exits | 153 | $474.8M |
All 13F filers, Q3 2024 → Q4 2024: 16,499,330 shares bought and 15,777,702 shares sold, net +721,628 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 1,561 holders
| Capital World Investors | 1.74% | Add +5.7% | 28,325,695 | $11.4B |
| Vanguard Group Inc. | 0.16% | Add +0.4% | 23,258,288 | $9.4B |
| BlackRock, Inc. | 0.18% | Add +0.2% | 21,825,470 | $8.8B |
| State Street Corp. | 0.19% | Add +1.4% | 11,979,405 | $4.8B |
| Capital Research Global Investors | 0.86% | Add +15.8% | 10,428,951 | $4.2B |
| FMR LLC | 0.22% | Reduce -12.4% | 9,219,046 | $3.7B |
| JPMorgan Chase & Co. | 0.20% | Reduce -8.9% | 6,313,107 | $2.5B |
| Wellington Management Group LLP | 0.44% | Add +23.3% | 5,916,084 | $2.4B |
| Geode Capital Management, LLC | 0.18% | Reduce -4.8% | 5,648,236 | $2.3B |
| Jennison Associates LLC | 1.06% | Reduce -22.2% | 4,317,762 | $1.7B |
| Alliancebernstein L.P. | 0.54% | Reduce -46.8% | 3,920,020 | $1.6B |
| Loomis Sayles & Co. L P | 1.92% | Add +23.0% | 3,772,789 | $1.5B |
| Norges Bank | 0.18% | Add +0.1% | 3,414,324 | $1.4B |
| Amundi | 0.47% | Reduce -12.7% | 3,281,205 | $1.4B |
| Morgan Stanley | 0.09% | Add +4.4% | 3,171,387 | $1.3B |
| Edgewood Management LLC | 3.42% | Add +91.2% | 2,956,608 | $1.2B |
| Janus Henderson Group PLC | 0.58% | Add +12.6% | 2,833,889 | $1.1B |
| Northern Trust Corp. | 0.16% | Add +15.0% | 2,721,049 | $1.1B |
| Bank of America Corp. | 0.09% | Reduce -7.3% | 2,419,353 | $974.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.22% | Reduce -4.6% | 2,329,219 | $938.0M |
| Massachusetts Financial Services Co. | 0.29% | Reduce -21.2% | 2,288,498 | $921.6M |
| Ameriprise Financial Inc. | 0.21% | Add +7.7% | 2,015,523 | $811.6M |
| Invesco Ltd. | 0.14% | Reduce -2.3% | 1,898,457 | $764.5M |
| Legal & General Group Plc | 0.20% | Reduce -1.1% | 1,884,153 | $758.7M |
| Clearbridge Investments, LLC | 0.61% | Reduce -6.2% | 1,850,858 | $745.3M |
| Parnassus Investments, LLC | 1.62% | New | 1,815,950 | $731.3M |
| Bank of New York Mellon Corp | 0.13% | Reduce -1.5% | 1,759,216 | $708.4M |
| T. Rowe Price Associates Inc. | 0.08% | Reduce -4.4% | 1,690,700 | $680.8M |
| Charles Schwab Investment Management Inc. | 0.12% | Add +2.3% | 1,663,849 | $670.0M |
| Royal Bank of Canada | 0.13% | Reduce -7.4% | 1,450,959 | $584.3M |
| Goldman Sachs Group Inc. | 0.11% | Add +3.2% | 1,401,734 | $564.5M |
| Renaissance Technologies | 0.83% | Reduce -14.4% | 1,397,209 | $562.7M |
| Deutsche Bank AG | 0.22% | Add +5.8% | 1,389,605 | $559.6M |
| WCM Investment Management, LLC | 1.03% | New | 1,091,522 | $435.9M |
| Nuveen Asset Management, LLC | 0.12% | Add +33.2% | 1,051,111 | $423.3M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.42% | Reduce -6.4% | 970,662 | $390.9M |
| California Public Employees Retirement System | 0.24% | Reduce -9.1% | 880,214 | $354.5M |
| HSBC Holdings PLC | 0.22% | Add +2.2% | 873,755 | $351.7M |
| UBS Group AG | 0.08% | Add +11.5% | 863,036 | $347.5M |
| Barclays PLC | 0.17% | Reduce -10.3% | 843,075 | $339.5M |
| Assenagon Asset Management S.A. | 0.61% | Add +169.4% | 839,672 | $338.1M |
| Harding Loevner LP | 2.24% | Reduce -28.5% | 823,627 | $331.7M |
| Franklin Resources Inc. | 0.09% | Add +59.5% | 760,517 | $306.3M |
| Swiss National Bank | 0.20% | Reduce -4.8% | 729,200 | $293.6M |
| Voya Investment Management LLC | 0.34% | Reduce -25.5% | 698,706 | $281.3M |
| Wells Fargo & Company | 0.07% | Reduce -16.9% | 689,652 | $277.7M |
| Artisan Partners Limited Partnership | 0.41% | Add +20.8% | 664,523 | $267.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.18% | Reduce -1.9% | 659,533 | $265.6M |
| Dimensional Fund Advisors LP | 0.06% | Reduce -3.1% | 627,517 | $252.7M |
| BNP Paribas Financial Markets | 0.19% | Add +34.7% | 596,555 | $240.2M |
| Bank of Montreal | 0.12% | Add +4.3% | 581,181 | $234.0M |
| Natixis Advisors, LLC | 0.42% | Add +20.7% | 557,644 | $224.6M |
| Manufacturers Life Insurance Company, The | 0.19% | Reduce -12.3% | 545,366 | $219.6M |
| National Pension Service | 0.20% | Add +3.2% | 527,474 | $212.4M |
| Lazard Asset Management LLC | 0.34% | Add +6487.2% | 526,119 | $211.9M |
| Pictet Asset Management Holding SA | 0.23% | Add +0.3% | 519,668 | $209.3M |
| DekaBank Deutsche Girozentrale | 0.38% | No change | 506,457 | $205.0M |
| Bellevue Group AG | 3.78% | Reduce -14.7% | 487,434 | $196.3M |
| American Century Companies Inc. | 0.11% | Reduce -2.4% | 473,360 | $190.6M |
| Raymond James Financial Inc. | 0.07% | — | 471,906 | $190.0M |
| TD Asset Management Inc | 0.17% | Reduce -10.2% | 469,068 | $188.9M |
| Citigroup Inc. | 0.18% | Reduce -21.5% | 462,068 | $186.1M |
| Swedbank AB | 0.23% | Reduce -21.1% | 456,587 | $183.9M |
| Chevy Chase Trust Holdings, LLC | 0.55% | Reduce -0.5% | 444,701 | $179.1M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.17% | Add +8.1% | 438,091 | $178.4M |
| Rhumbline Advisers | 0.16% | Reduce -1.6% | 442,361 | $178.1M |
| Neuberger Berman Group LLC | 0.14% | Add +1.2% | 434,311 | $174.9M |
| Envestnet Asset Management Inc. | 0.05% | Add +4.9% | 422,698 | $170.2M |
| Public Employees Retirement Association of Colorado | 0.67% | Reduce -2.3% | 418,563 | $168.6M |
| California State Teachers Retirement System | 0.19% | Reduce -2.9% | 400,670 | $161.3M |
| Principal Financial Group Inc. | 0.09% | Reduce -3.4% | 396,532 | $159.7M |
| Bank Julius Baer & Co. Ltd, Zurich | 0.49% | Add +9.9% | 368,967 | $159.0M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.39% | Reduce -1.6% | 389,657 | $156.9M |
| Canada Pension Plan Investment Board | 0.14% | Add +30.1% | 369,354 | $148.7M |
| Royal London Asset Management Ltd. | 0.36% | Add +0.0% | 363,278 | $146.3M |
| New York State Common Retirement Fund | 0.20% | Add +0.8% | 362,334 | $145.9M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.40% | Add +9.2% | 349,477 | $140.7M |
| APG Asset Management N.V. | 0.39% | Add +189.7% | 359,285 | $139.7M |
| Aberdeen Group plc | 0.26% | Reduce -6.3% | 347,570 | $139.4M |
| ProShare Advisors LLC | 0.32% | Add +18.2% | 344,526 | $138.7M |
| Capital International Investors | 0.03% | New | 342,512 | $137.9M |
| Nordea Investment Management AB | 0.14% | Add +19.4% | 342,429 | $137.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.28% | — | 339,508 | $136.7M |
| Millennium Management | 0.11% | Add +95.0% | 310,643 | $125.1M |
| Victory Capital Management Inc. | 0.12% | Reduce -1.7% | 305,146 | $122.9M |
| Handelsbanken Fonder AB | 0.46% | Reduce -28.1% | 296,036 | $119.2M |
| Lansforsakringar Fondforvaltning AB (publ) | 0.44% | — | 289,416 | $116.5M |
| Robeco Institutional Asset Management B.V. | 0.22% | Reduce -3.3% | 286,756 | $115.5M |
| Sei Investments Co. | 0.14% | Add +28.6% | 275,135 | $110.8M |
| Ensign Peak Advisors, Inc | 0.20% | Add +55.0% | 275,082 | $110.8M |
| CANADA LIFE ASSURANCE Co | 0.19% | Reduce -15.2% | 269,878 | $108.6M |
| D. E. Shaw & Co. | 0.13% | Add +92.0% | 265,684 | $107.0M |
| Candriam S.C.A. | 0.60% | Reduce -16.9% | 258,622 | $104.1M |
| Allianz Asset Management GmbH | 0.15% | Reduce -1.3% | 255,623 | $102.9M |
| State Board of Administration of Florida Retirement System | 0.19% | Reduce -5.2% | 248,049 | $99.9M |
| AQR Capital Management | 0.13% | Reduce -48.9% | 245,785 | $99.0M |
| Cerity Partners LLC | 0.21% | Add +3.9% | 238,029 | $97.5M |
| Russell Investments Group, Ltd. | 0.13% | Add +4.1% | 239,342 | $96.3M |
| Armistice Capital, LLC | 2.10% | Add +385.6% | 224,016 | $90.2M |
| New York State Teachers Retirement System | 0.19% | Reduce -4.6% | 221,252 | $89.1M |
"% of holder's portfolio" is VRTX's weight in each manager's 13F, not the share of Vertex Pharmaceuticals Inc. the manager owns.