Vertex PharmaceuticalsVRTX
13F holders, Q1 2026 (March 31)1,698holders +26
127new positions
102sold out
9famous investors
$446.32avg. 13F price*
At the end of Q1 2026, 1,698 institutions reported holding Vertex Pharmaceuticals Inc. (VRTX) in their 13F filings, up 26 from Q4 2025. 127 opened new positions and 102 sold out. The largest holders were Capital World Investors ($11.3B), BlackRock, Inc. ($10.7B) and Capital Research Global Investors ($9.4B). 9 famous investors held it, including Jim Simons / Peter Brown (0.3% of Renaissance Technologies's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio).
- Company
- Vertex Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 92532F100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 127 | $486.7M |
| Exits | 102 | $822.3M |
All 13F filers, Q4 2025 → Q1 2026: 12,152,424 shares bought and 12,883,755 shares sold, net −731,331 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 1,698 holders
| Capital World Investors | 1.55% | Reduce -0.6% | 25,368,124 | $11.3B |
| BlackRock, Inc. | 0.19% | Add +0.9% | 23,969,517 | $10.7B |
| Capital Research Global Investors | 1.47% | Add +22.0% | 21,125,964 | $9.4B |
| Vanguard Capital Management LLC | 0.18% | — | 16,512,810 | $7.4B |
| State Street Corp. | 0.18% | Add +0.3% | 11,730,139 | $5.2B |
| Invesco Ltd. | 0.34% | Add +0.5% | 7,892,611 | $3.5B |
| JPMorgan Chase & Co. | 0.21% | Add +16.4% | 7,033,156 | $3.1B |
| Geode Capital Management, LLC | 0.17% | Add +2.6% | 6,139,621 | $2.7B |
| Vanguard Portfolio Management LLC | 0.12% | — | 5,145,609 | $2.3B |
| Capital International Investors | 0.54% | Add +8.3% | 5,126,077 | $2.3B |
| Loomis Sayles & Co. L P | 2.41% | Reduce -0.7% | 4,003,821 | $1.8B |
| Alliancebernstein L.P. | 0.57% | Reduce -13.0% | 3,910,786 | $1.8B |
| Wellington Management Group LLP | 0.27% | Reduce -15.9% | 3,212,589 | $1.4B |
| Morgan Stanley | 0.09% | Add +2.2% | 3,188,881 | $1.4B |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.28% | Add +1.9% | 3,057,396 | $1.4B |
| Bank of America Corp. | 0.09% | Reduce -2.0% | 2,878,183 | $1.3B |
| Jennison Associates LLC | 0.84% | Reduce -15.7% | 2,740,059 | $1.2B |
| Clearbridge Investments, LLC | 1.05% | Reduce -5.6% | 2,700,975 | $1.2B |
| Ameriprise Financial Inc. | 0.27% | Add +16.3% | 2,633,481 | $1.2B |
| Northern Trust Corp. | 0.15% | Reduce -0.6% | 2,564,264 | $1.1B |
| Goldman Sachs Group Inc. | 0.14% | Add +37.8% | 2,417,875 | $1.1B |
| Janus Henderson Group PLC | 0.45% | Reduce -4.1% | 2,131,527 | $951.8M |
| FMR LLC | 0.05% | Reduce -8.7% | 2,020,265 | $902.1M |
| Legal & General Group Plc | 0.20% | Reduce -0.7% | 1,955,764 | $873.3M |
| Charles Schwab Investment Management Inc. | 0.13% | Add +3.3% | 1,920,871 | $857.7M |
| Victory Capital Management Inc. | 0.55% | Reduce -43.7% | 1,888,521 | $843.3M |
| T. Rowe Price Associates Inc. | 0.09% | Reduce -22.8% | 1,760,122 | $786.0M |
| Bank of New York Mellon Corp | 0.13% | Add +3.9% | 1,586,427 | $708.4M |
| Deutsche Bank AG | 0.23% | Reduce -13.1% | 1,537,736 | $686.7M |
| Amundi | 0.18% | Add +12.9% | 1,472,496 | $657.5M |
| Vanguard Fiduciary Trust Co. | 0.17% | — | 1,465,724 | $654.5M |
| WCM Investment Management, LLC | 1.13% | Reduce -0.7% | 1,121,341 | $496.9M |
| Royal Bank of Canada | 0.09% | Reduce -6.9% | 1,111,871 | $496.5M |
| Nuveen, LLC | 0.13% | Add +4.0% | 1,084,495 | $484.3M |
| Dimensional Fund Advisors LP | 0.09% | Add +4.6% | 989,342 | $441.8M |
| Edgewood Management LLC | 2.61% | Reduce -14.6% | 905,129 | $404.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.44% | Add +26.6% | 848,047 | $378.7M |
| American Century Companies Inc. | 0.19% | Reduce -4.2% | 813,285 | $363.2M |
| Wells Fargo & Company | 0.07% | Add +0.4% | 744,995 | $332.7M |
| Swiss National Bank | 0.19% | Add +6.0% | 744,600 | $332.5M |
| Citigroup Inc. | 0.19% | Add +26.5% | 682,807 | $304.9M |
| Bellevue Group AG | 7.25% | Add +0.1% | 681,908 | $304.5M |
| Barclays PLC | 0.11% | Reduce -21.8% | 663,263 | $296.2M |
| HSBC Holdings PLC | 0.17% | Add +4.0% | 655,443 | $292.7M |
| Arrowstreet Capital, Limited Partnership | 0.15% | Add +7.6% | 638,950 | $285.3M |
| UBS Group AG | 0.05% | Add +13.4% | 630,618 | $281.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.18% | Reduce -6.1% | 614,448 | $274.4M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.18% | Add +5.5% | 597,497 | $266.8M |
| Vanguard Global Advisers, LLC | 0.13% | — | 555,733 | $248.2M |
| Natixis Advisors, LLC | 0.34% | Add +5.0% | 554,024 | $247.4M |
| Manufacturers Life Insurance Company, The | 0.21% | Reduce -0.8% | 553,243 | $247.0M |
| Neuberger Berman Group LLC | 0.19% | Add +1.0% | 551,522 | $246.3M |
| Franklin Resources Inc. | 0.06% | Add +0.1% | 551,132 | $246.1M |
| Assenagon Asset Management S.A. | 0.38% | Reduce -35.5% | 537,248 | $239.9M |
| National Pension Service | 0.18% | Add +0.2% | 532,069 | $237.6M |
| Voya Investment Management LLC | 0.28% | Reduce -6.3% | 527,047 | $234.9M |
| DekaBank Deutsche Girozentrale | 0.38% | No change | 506,457 | $230.0M |
| B. Metzler seel. Sohn & Co. AG | 2.12% | Reduce -0.8% | 511,036 | $228.2M |
| Envestnet Asset Management Inc. | 0.06% | Add +6.8% | 503,564 | $224.9M |
| California Public Employees Retirement System | 0.14% | Reduce -9.5% | 503,374 | $224.8M |
| Raymond James Financial Inc. | 0.06% | Add +6.3% | 444,496 | $198.5M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.17% | — | 442,177 | $197.4M |
| Life Cycle Investment Partners Ltd | 1.25% | Add +20.1% | 440,409 | $196.7M |
| Principal Financial Group Inc. | 0.10% | Add +2.8% | 426,523 | $190.5M |
| Rhumbline Advisers | 0.16% | Reduce -1.9% | 423,140 | $188.9M |
| Renaissance Technologies | 0.29% | Reduce -16.5% | 421,688 | $188.3M |
| BNP Paribas Financial Markets | 0.12% | Reduce -25.7% | 415,625 | $185.6M |
| Chevy Chase Trust Holdings, LLC | 0.52% | Reduce -0.2% | 407,615 | $182.0M |
| Robeco Institutional Asset Management B.V. | 0.26% | Add +1.9% | 401,644 | $179.4M |
| Bank of Montreal | 0.07% | Reduce -8.7% | 390,476 | $174.4M |
| Two Sigma Investments, LP | 0.15% | Add +9001.0% | 378,146 | $168.9M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.37% | Add +6.7% | 377,013 | $168.4M |
| ProShare Advisors LLC | 0.25% | Reduce -18.3% | 373,532 | $166.8M |
| California State Teachers Retirement System | 0.18% | Reduce -3.2% | 373,481 | $166.8M |
| Russell Investments Group, Ltd. | 0.18% | Reduce -3.6% | 367,691 | $164.0M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.15% | Reduce -54.6% | 364,513 | $162.8M |
| Citadel Advisors | 0.11% | Reduce -20.6% | 339,298 | $151.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.26% | Add +1.0% | 338,347 | $151.0M |
| Pictet Asset Management Holding SA | 0.16% | Reduce -55.1% | 337,569 | $150.1M |
| Massachusetts Financial Services Co. | 0.05% | Add +54.5% | 327,498 | $149.4M |
| Marshall Wace, LLP | 0.15% | Add +55.4% | 317,058 | $141.6M |
| Bank Julius Baer & Co. Ltd, Zurich | 0.43% | Reduce -13.4% | 317,406 | $141.5M |
| Harding Loevner LP | 1.44% | Reduce -20.0% | 313,546 | $140.0M |
| AMF Tjanstepension AB | 0.93% | Add +114.4% | 312,917 | $139.7M |
| Public Employees Retirement Association of Colorado | 0.55% | Reduce -5.5% | 311,750 | $139.2M |
| First Trust Advisors LP | 0.10% | Add +52.3% | 306,461 | $136.8M |
| Cerity Partners LLC | 0.19% | Add +13.4% | 296,654 | $132.5M |
| New York State Common Retirement Fund | 0.18% | Reduce -1.7% | 292,414 | $130.6M |
| National Bank of Canada | 0.12% | Add +14.1% | 272,117 | $121.5M |
| Swedbank AB | 0.13% | Add +4.2% | 271,553 | $121.3M |
| LPL Financial LLC | 0.03% | Reduce -3.2% | 268,062 | $119.7M |
| Royal London Asset Management Ltd. | 0.24% | Reduce -7.8% | 252,192 | $112.6M |
| Adage Capital Partners Gp, L.L.C. | 0.17% | Reduce -7.5% | 251,990 | $112.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.26% | Reduce -27.1% | 251,711 | $112.4M |
| D. E. Shaw & Co. | 0.09% | New | 248,960 | $111.2M |
| Man Group plc | 0.22% | Reduce -37.8% | 236,798 | $105.7M |
| Aberdeen Group plc | 0.17% | Reduce -10.9% | 233,480 | $104.3M |
| Candriam S.C.A. | 0.53% | Add +1.6% | 228,915 | $102.2M |
| TD Asset Management Inc | 0.08% | Add +25.0% | 228,195 | $101.9M |
| State Board of Administration of Florida Retirement System | 0.19% | Reduce -0.6% | 224,655 | $100.3M |
"% of holder's portfolio" is VRTX's weight in each manager's 13F, not the share of Vertex Pharmaceuticals Inc. the manager owns.