Vertex PharmaceuticalsVRTX
13F holders, Q3 2025 (September 30)1,522holders −41
129new positions
155sold out
12famous investors
$390.93avg. 13F price*
At the end of Q3 2025, 1,522 institutions reported holding Vertex Pharmaceuticals Inc. (VRTX) in their 13F filings, down 41 from Q2 2025. 129 opened new positions and 155 sold out. The largest holders were Capital World Investors ($10.1B), Vanguard Group Inc. ($9.5B) and BlackRock, Inc. ($8.7B). 12 famous investors held it, including Jim Simons / Peter Brown (0.4% of Renaissance Technologies's portfolio), Paul Tudor Jones (0.1% of Tudor Investment Corporation's portfolio) and Cathie Wood (0.1% of ARK Investment Management's portfolio).
- Company
- Vertex Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 92532F100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 129 | $525.1M |
| Exits | 155 | $718.5M |
All 13F filers, Q2 2025 → Q3 2025: 12,912,089 shares bought and 18,291,029 shares sold, net −5,378,940 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 1,522 holders
| Capital World Investors | 1.39% | Reduce -9.8% | 25,910,587 | $10.1B |
| Vanguard Group Inc. | 0.14% | Add +1.0% | 24,216,865 | $9.5B |
| BlackRock, Inc. | 0.15% | Add +1.7% | 22,253,047 | $8.7B |
| Capital Research Global Investors | 1.22% | Add +2.8% | 16,553,281 | $6.5B |
| State Street Corp. | 0.16% | Reduce -1.4% | 11,606,000 | $4.5B |
| JPMorgan Chase & Co. | 0.16% | Add +9.6% | 6,434,778 | $2.5B |
| Geode Capital Management, LLC | 0.15% | Add +0.8% | 5,973,745 | $2.3B |
| Wellington Management Group LLP | 0.33% | Reduce -0.9% | 4,772,042 | $1.9B |
| Capital International Investors | 0.30% | Add +77.9% | 4,689,059 | $1.8B |
| Alliancebernstein L.P. | 0.56% | Add +3.3% | 4,522,586 | $1.8B |
| Loomis Sayles & Co. L P | 1.92% | Add +8.1% | 4,122,128 | $1.6B |
| Jennison Associates LLC | 0.79% | Reduce -43.8% | 3,454,947 | $1.4B |
| FMR LLC | 0.07% | Reduce -48.4% | 3,303,768 | $1.3B |
| Morgan Stanley | 0.07% | Reduce -6.7% | 3,108,405 | $1.2B |
| T. Rowe Price Associates Inc. | 0.13% | Reduce -3.7% | 3,043,805 | $1.2B |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.25% | Reduce -5.9% | 2,887,117 | $1.1B |
| Bank of America Corp. | 0.08% | Add +1.2% | 2,840,424 | $1.1B |
| Clearbridge Investments, LLC | 0.78% | Add +73.2% | 2,645,764 | $1.0B |
| Northern Trust Corp. | 0.13% | Reduce -1.1% | 2,627,887 | $1.0B |
| Ameriprise Financial Inc. | 0.21% | Add +4.4% | 2,276,927 | $891.7M |
| Janus Henderson Group PLC | 0.38% | Reduce -19.1% | 2,119,107 | $829.9M |
| Invesco Ltd. | 0.13% | Add +5.7% | 2,096,797 | $821.2M |
| Victory Capital Management Inc. | 0.47% | Add +4.3% | 2,247,566 | $787.3M |
| Legal & General Group Plc | 0.17% | Add +3.3% | 1,952,297 | $764.6M |
| Charles Schwab Investment Management Inc. | 0.11% | Add +3.2% | 1,829,931 | $716.7M |
| Parnassus Investments, LLC | 1.49% | Reduce -3.7% | 1,648,433 | $645.6M |
| Deutsche Bank AG | 0.21% | Add +13.7% | 1,600,456 | $626.8M |
| Bank of New York Mellon Corp | 0.11% | Reduce -2.0% | 1,569,165 | $614.5M |
| Edgewood Management LLC | 2.06% | Reduce -39.4% | 1,487,542 | $582.6M |
| Goldman Sachs Group Inc. | 0.08% | Reduce -23.1% | 1,484,658 | $581.5M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.48% | Add +11.3% | 1,341,470 | $525.4M |
| Royal Bank of Canada | 0.08% | Reduce -13.8% | 1,193,709 | $467.5M |
| WCM Investment Management, LLC | 0.95% | Reduce -1.2% | 1,150,132 | $454.7M |
| Amundi | 0.14% | Reduce -1.3% | 1,118,971 | $450.8M |
| Nuveen, LLC | 0.11% | Add +1.5% | 1,077,710 | $422.1M |
| Pictet Asset Management Holding SA | 0.30% | Add +7.6% | 791,458 | $310.5M |
| Dimensional Fund Advisors LP | 0.07% | Add +31.4% | 783,586 | $306.9M |
| UBS Group AG | 0.06% | Add +10.4% | 773,048 | $302.8M |
| Assenagon Asset Management S.A. | 0.44% | Add +214.6% | 763,703 | $299.1M |
| Barclays PLC | 0.11% | Reduce -9.8% | 742,487 | $290.8M |
| Swiss National Bank | 0.17% | Reduce -4.9% | 740,300 | $289.9M |
| Renaissance Technologies | 0.38% | Reduce -26.8% | 735,888 | $288.2M |
| Wells Fargo & Company | 0.06% | Add +2.2% | 717,326 | $280.9M |
| Sumitomo Mitsui Trust Group, Inc. | 0.16% | Add +7.0% | 700,673 | $274.4M |
| HSBC Holdings PLC | 0.15% | Reduce -0.7% | 637,332 | $249.5M |
| California Public Employees Retirement System | 0.14% | Reduce -15.5% | 612,507 | $239.9M |
| Squarepoint Ops LLC | 0.51% | Add +246.0% | 607,836 | $238.1M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.15% | Add +3.8% | 544,978 | $213.4M |
| Lazard Asset Management LLC | 0.29% | Add +13.4% | 544,823 | $213.4M |
| Citigroup Inc. | 0.15% | Reduce -9.9% | 539,995 | $211.5M |
| Natixis Advisors, LLC | 0.31% | Reduce -0.6% | 537,194 | $210.4M |
| Raymond James Financial Inc. | 0.07% | Add +7.2% | 535,685 | $209.8M |
| Neuberger Berman Group LLC | 0.15% | Add +14.9% | 527,491 | $206.6M |
| National Pension Service | 0.16% | Add +2.9% | 512,113 | $200.6M |
| Manufacturers Life Insurance Company, The | 0.17% | Reduce -6.7% | 510,165 | $199.8M |
| DekaBank Deutsche Girozentrale | 0.34% | No change | 506,457 | $199.7M |
| Bellevue Group AG | 4.12% | Add +14.5% | 505,805 | $198.1M |
| Massachusetts Financial Services Co. | 0.06% | Reduce -60.8% | 503,160 | $197.1M |
| Adage Capital Partners Gp, L.L.C. | 0.30% | Add +170.8% | 482,495 | $189.0M |
| Manning & Napier Advisors LLC | 2.39% | Add +103.3% | 474,822 | $187.7M |
| Envestnet Asset Management Inc. | 0.05% | Add +4.8% | 470,755 | $184.4M |
| Franklin Resources Inc. | 0.05% | Reduce -11.6% | 462,954 | $181.3M |
| Harding Loevner LP | 1.31% | Reduce -35.9% | 455,988 | $178.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.46% | Add +2.7% | 456,333 | $178.6M |
| American Century Companies Inc. | 0.09% | Reduce -16.5% | 449,193 | $175.9M |
| Rhumbline Advisers | 0.14% | Reduce -1.4% | 447,928 | $175.4M |
| Voya Investment Management LLC | 0.19% | Reduce -38.2% | 432,257 | $168.8M |
| Bank of Montreal | 0.07% | Add +15.5% | 419,458 | $164.3M |
| Chevy Chase Trust Holdings, LLC | 0.45% | Reduce -5.1% | 418,509 | $163.9M |
| Principal Financial Group Inc. | 0.08% | Reduce -0.8% | 406,500 | $159.2M |
| California State Teachers Retirement System | 0.16% | Reduce -0.8% | 394,582 | $154.5M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.35% | Reduce -1.5% | 388,311 | $152.1M |
| Arrowstreet Capital, Limited Partnership | 0.09% | Add +520.1% | 381,195 | $149.3M |
| Robeco Institutional Asset Management B.V. | 0.22% | Add +15.2% | 379,371 | $148.6M |
| Bank Julius Baer & Co. Ltd, Zurich | 0.42% | Reduce -3.8% | 376,495 | $147.5M |
| Man Group plc | 0.28% | Add +184.3% | 362,774 | $142.1M |
| Nordea Investment Management AB | 0.12% | Add +1373.1% | 361,085 | $140.1M |
| Russell Investments Group, Ltd. | 0.15% | Add +8.7% | 341,048 | $133.7M |
| Public Employees Retirement Association of Colorado | 0.48% | Reduce -14.4% | 336,091 | $131.6M |
| ProShare Advisors LLC | 0.27% | Reduce -16.8% | 333,732 | $130.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.21% | Add +1.8% | 319,467 | $125.1M |
| B. Metzler seel. Sohn & Co. AG | 1.09% | Reduce -1.3% | 315,422 | $123.5M |
| Aberdeen Group plc | 0.20% | Add +9.3% | 314,889 | $123.3M |
| Ensign Peak Advisors, Inc | 0.20% | Add +76.2% | 311,998 | $122.2M |
| New York State Common Retirement Fund | 0.16% | Reduce -9.3% | 308,577 | $120.9M |
| Royal London Asset Management Ltd. | 0.23% | Reduce -2.2% | 277,196 | $108.6M |
| CANADA LIFE ASSURANCE Co | 0.16% | Add +1.3% | 274,136 | $108.3M |
| Alyeska Investment Group, L.P. | 0.32% | Add +311.0% | 267,169 | $104.6M |
| LPL Financial LLC | 0.03% | Add +9.8% | 264,182 | $103.5M |
| Cerity Partners LLC | 0.16% | Reduce -1.9% | 258,808 | $101.4M |
| BNP Paribas Financial Markets | 0.08% | Reduce -52.1% | 254,343 | $99.6M |
| Swedbank AB | 0.10% | Reduce -0.1% | 254,096 | $99.5M |
| Jane Street Group, LLC | 0.11% | New | 248,267 | $97.2M |
| National Bank of Canada | 0.11% | Add +3.1% | 247,941 | $97.1M |
| Canada Pension Plan Investment Board | 0.07% | Add +47.2% | 246,364 | $96.5M |
| State Board of Administration of Florida Retirement System | 0.16% | Reduce -6.9% | 233,612 | $91.5M |
| Prudential Financial Inc. | 0.11% | Add +25.3% | 225,814 | $88.4M |
| Capital International Sarl | 1.53% | Add +1.1% | 225,734 | $88.4M |
| Macquarie Group Ltd. | 0.10% | Reduce -2.3% | 223,556 | $87.6M |
| Caisse de depot et placement du Quebec | 0.16% | Add +245.2% | 222,262 | $87.0M |
"% of holder's portfolio" is VRTX's weight in each manager's 13F, not the share of Vertex Pharmaceuticals Inc. the manager owns.