X4 PharmaceuticalsXFOR
13F holders, Q4 2025 (December 31)76holders +36
37new positions
4sold out
3famous investors
$4.00avg. 13F price*
At the end of Q4 2025, 76 institutions reported holding X4 Pharmaceuticals Inc. (XFOR) in their 13F filings, up 36 from Q3 2025. 37 opened new positions and 4 sold out. The largest holders were Empery Asset Management, LP ($35.8M), FMR LLC ($34.0M) and Morgan Stanley ($32.8M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- X4 Pharmaceuticals Inc.
- CUSIP
- 98420X202
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $134.6M |
| Exits | 4 | $4.4M |
All 13F filers, Q3 2025 → Q4 2025: 58,956,554 shares bought and 1,941,392 shares sold, net +57,015,162 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 76 holders
| Empery Asset Management, LP | 31.70% | — | 8,951,105 | $35.8M |
| FMR LLC | 0.00% | New | 8,499,100 | $34.0M |
| Morgan Stanley | 0.00% | Add +220072.1% | 8,208,015 | $32.8M |
| Bain Capital Life Sciences Investors, LLC | 2.45% | Add +227.0% | 7,967,454 | $31.9M |
| Perceptive Advisors LLC | 0.46% | New | 6,314,452 | $25.3M |
| Saturn V Capital Management LP | 4.26% | New | 5,800,530 | $23.2M |
| Deep Track Capital, LP | 0.46% | Add +346.7% | 5,013,661 | $20.1M |
| Kalehua Capital Management LLC | 14.73% | — | 3,722,840 | $14.9M |
| Vanguard Group Inc. | 0.00% | Add +734.0% | 3,423,662 | $13.7M |
| Braidwell LP | 0.52% | New | 3,368,904 | $13.5M |
| Blackstone Inc. | 0.05% | New | 2,681,922 | $10.7M |
| Rosalind Advisors, Inc. | 3.80% | Add +68.7% | 2,605,920 | $10.4M |
| Trails Edge Capital Partners, LP | 2.54% | — | 2,571,478 | $10.3M |
| Nantahala Capital Management, LLC | 0.59% | Add +9.9% | 2,449,468 | $9.8M |
| BVF Inc. | 0.30% | No change | 2,233,742 | $8.9M |
| Samsara Biocapital, LLC | 0.81% | New | 1,960,000 | $7.8M |
| Siren, L.L.C. | 0.18% | New | 1,500,000 | $6.0M |
| BlackRock, Inc. | 0.00% | Add +1880.8% | 1,226,808 | $4.9M |
| Woodline Partners LP | 0.02% | New | 1,000,855 | $4.0M |
| Geode Capital Management, LLC | 0.00% | Add +1080.6% | 940,447 | $3.8M |
| Stempoint Capital LP | 0.62% | Add +61.8% | 898,465 | $3.6M |
| Goldman Sachs Group Inc. | 0.00% | New | 831,890 | $3.3M |
| Point72 Asset Management | 0.01% | Add +3630.1% | 808,154 | $3.2M |
| Stonepine Capital Management, LLC | 1.88% | Reduce -43.8% | 593,573 | $2.4M |
| Silverarc Capital Management, LLC | 0.21% | New | 357,387 | $1.4M |
| State Street Corp. | 0.00% | Add +411.8% | 198,234 | $793K |
| Northern Trust Corp. | 0.00% | New | 178,235 | $713K |
| Pale Fire Capital SE | 0.09% | Reduce -7.3% | 167,590 | $670K |
| Affinity Asset Advisors, LLC | 0.04% | New | 145,000 | $580K |
| Citadel Advisors | 0.00% | New | 128,675 | $515K |
| Palumbo Wealth Management LLC | 0.11% | Add +18.9% | 113,357 | $453K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 109,200 | $437K |
| Jane Street Group, LLC | 0.00% | New | 91,413 | $366K |
| Marshall Wace, LLP | 0.00% | New | 80,456 | $322K |
| ExodusPoint Capital Management, LP | 0.00% | New | 79,072 | $316K |
| Qube Research & Technologies Ltd | 0.00% | New | 67,747 | $271K |
| Charles Schwab Investment Management Inc. | 0.00% | New | 66,788 | $267K |
| Balyasny Asset Management L.P. | 0.00% | New | 64,505 | $258K |
| Barclays PLC | 0.00% | New | 57,500 | $230K |
| Millennium Management | 0.00% | Reduce -13.6% | 55,978 | $224K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | New | 43,259 | $173K |
| Bank of America Corp. | 0.00% | Add +85.3% | 35,761 | $143K |
| Citigroup Inc. | 0.00% | Add +100937.5% | 32,332 | $129K |
| Hudson Bay Capital Management LP | 0.00% | New | 32,239 | $129K |
| Jefferies Financial Group Inc. | 0.00% | New | 26,118 | $104K |
| Man Group plc | 0.00% | New | 24,187 | $97K |
| Virtu Financial LLC | 0.00% | New | 22,489 | $90K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 22,200 | $89K |
| Susquehanna International Group, LLP | 0.00% | New | 22,135 | $89K |
| Stifel Financial Corp. | 0.00% | New | 20,496 | $82K |
| Two Sigma Investments, LP | 0.00% | Add +24.4% | 17,246 | $69K |
| Creative Planning | 0.00% | New | 16,427 | $66K |
| Caxton Corp. | 1.45% | New | 15,557 | $62K |
| Squarepoint Ops LLC | 0.00% | New | 12,518 | $50K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -2.2% | 10,446 | $42K |
| Indivisible Partners | 0.00% | — | 10,000 | $40K |
| JPMorgan Chase & Co. | 0.00% | Add +13781.8% | 4,581 | $18K |
| UBS Group AG | 0.00% | Reduce -97.4% | 4,129 | $17K |
| Group One Trading LLC | 0.00% | No change | 3,998 | $16K |
| Signaturefd, LLC | 0.00% | New | 2,754 | $11K |
| CIBC Private Wealth Group LLC | 0.00% | No change | 2,166 | $9K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,759 | $7K |
| Russell Investments Group, Ltd. | 0.00% | No change | 729 | $3K |
| Allworth Financial LP | 0.00% | New | 715 | $3K |
| Bleichroeder LP | 0.00% | No change | 595 | $2K |
| BNP Paribas Financial Markets | 0.00% | Reduce -7.8% | 511 | $2K |
| Farther Finance Advisors, LLC | 0.00% | New | 331 | $1K |
| Blue Trust, Inc. | 0.00% | No change | 284 | $1K |
| Fortitude Family Office, LLC | 0.00% | New | 137 | $548 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -76.8% | 50 | $200 |
| Jones Financial Companies LLLP | 0.00% | No change | 38 | $152 |
| NewEdge Advisors, LLC | 0.00% | No change | 33 | $132 |
| Rockefeller Capital Management L.P. | 0.00% | No change | 33 | $132 |
| HighMark Wealth Management LLC | 0.00% | No change | 6 | $24 |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 5 | $20 |
| Royal Bank of Canada | 0.00% | Reduce -95.9% | 104 | $0 |
"% of holder's portfolio" is XFOR's weight in each manager's 13F, not the share of X4 Pharmaceuticals Inc. the manager owns.