ZymeworksZYME
13F holders, Q2 2026 (June 30)202holders −10
22new positions
30sold out
5famous investors
$26.13avg. 13F price*
At the end of Q2 2026, 202 institutions reported holding Zymeworks Inc. (ZYME) in their 13F filings, down 10 from Q1 2026. 22 opened new positions and 30 sold out. The largest holders were EcoR1 Capital, LLC ($600.4M), Rubric Capital Management LP ($183.0M) and BlackRock, Inc. ($111.1M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Zymeworks Inc.
- CUSIP
- 98985Y108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 22 | $41.8M |
| Exits | 30 | $37.0M |
All 13F filers, Q1 2026 → Q2 2026: 4,153,408 shares bought and 6,049,831 shares sold, net −1,896,423 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 202 holders
| EcoR1 Capital, LLC | 29.77% | No change | 22,970,388 | $600.4M |
| Rubric Capital Management LP | 1.68% | No change | 7,000,000 | $183.0M |
| BlackRock, Inc. | 0.00% | Reduce -6.7% | 4,251,030 | $111.1M |
| Perceptive Advisors LLC | 1.70% | Add +19.2% | 4,182,953 | $109.3M |
| BVF Inc. | 2.44% | Reduce -2.3% | 3,649,142 | $95.4M |
| Morgan Stanley | 0.00% | Reduce -10.1% | 2,231,260 | $58.3M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.05% | Reduce -6.7% | 1,781,116 | $46.6M |
| Vanguard Capital Management LLC | 0.00% | Reduce -8.6% | 1,558,998 | $40.8M |
| Assenagon Asset Management S.A. | 0.04% | Add +72.0% | 1,252,027 | $32.7M |
| Nextech Invest Ltd. | 1.38% | No change | 1,113,946 | $29.1M |
| State Street Corp. | 0.00% | Add +7.5% | 1,088,216 | $28.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -12.7% | 994,955 | $26.0M |
| Citadel Advisors | 0.01% | Reduce -20.5% | 914,136 | $23.9M |
| Nomura Asset Management International Inc. | 0.04% | New | 889,802 | $23.3M |
| FMR LLC | 0.00% | Add +5.3% | 702,568 | $18.4M |
| Geode Capital Management, LLC | 0.00% | Add +4.9% | 692,410 | $18.1M |
| Prosight Management, LP | 3.04% | Add +25.1% | 674,434 | $17.6M |
| Qube Research & Technologies Ltd | 0.02% | Add +15.9% | 593,590 | $15.5M |
| Vanguard Portfolio Management LLC | 0.00% | Add +2.0% | 510,032 | $13.3M |
| Redmile Group, LLC | 0.86% | No change | 491,654 | $12.9M |
| Capricorn Fund Managers Ltd | 1.02% | Reduce -51.7% | 486,529 | $12.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -21.5% | 470,822 | $12.3M |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -43.7% | 418,497 | $10.9M |
| Deutsche Bank AG | 0.00% | Reduce -56.9% | 397,190 | $10.4M |
| Hillsdale Investment Management Inc. | 0.23% | Add +10.8% | 382,922 | $10.0M |
| First Trust Advisors LP | 0.01% | New | 340,363 | $8.9M |
| Granahan Investment Management, LLC | 0.31% | Add +34.0% | 336,157 | $8.8M |
| Northern Trust Corp. | 0.00% | Add +0.3% | 321,073 | $8.4M |
| Pictet Asset Management Holding SA | 0.01% | Add +3229.6% | 308,187 | $7.4M |
| Picton Mahoney Asset Management | 0.07% | Add +5.7% | 271,343 | $7.1M |
| Silvercrest Asset Management Group LLC | 0.04% | Add +36.7% | 223,766 | $5.8M |
| Bank of America Corp. | 0.00% | Reduce -7.5% | 219,071 | $5.7M |
| Wells Fargo & Company | 0.00% | Add +14.5% | 217,199 | $5.7M |
| SummitTX Capital, L.P. | 0.15% | Reduce -34.4% | 210,802 | $5.5M |
| Man Group plc | 0.01% | Add +11.0% | 210,779 | $5.5M |
| Federated Hermes, Inc. | 0.01% | Add +3.1% | 187,995 | $4.9M |
| Raymond James Financial Inc. | 0.00% | Reduce -5.7% | 166,416 | $4.4M |
| State of Wisconsin Investment Board | 0.01% | Add +135.3% | 155,579 | $4.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -17.7% | 152,416 | $4.0M |
| Kennedy Capital Management LLC | 0.07% | Reduce -1.9% | 145,386 | $3.8M |
| D. E. Shaw & Co. | 0.00% | Reduce -38.5% | 144,807 | $3.8M |
| Diadema Partners LP | 1.40% | No change | 142,132 | $3.7M |
| Citigroup Inc. | 0.00% | Add +15.0% | 131,441 | $3.4M |
| Bank of New York Mellon Corp | 0.00% | Add +5.6% | 131,106 | $3.4M |
| XTX Topco Ltd | 0.04% | Reduce -12.5% | 125,877 | $3.3M |
| Nuveen, LLC | 0.00% | Reduce -81.7% | 119,389 | $3.1M |
| Panagora Asset Management Inc. | 0.01% | Reduce -42.7% | 118,603 | $3.1M |
| UBS Group AG | 0.00% | Reduce -33.0% | 115,095 | $3.0M |
| Invesco Ltd. | 0.00% | Reduce -10.7% | 112,212 | $2.9M |
| AQR Capital Management | 0.00% | Add +22.7% | 111,282 | $2.9M |
| Wellington Management Group LLP | 0.00% | Reduce -20.7% | 110,014 | $2.9M |
| Tema ETFs LLC | 0.09% | Add +0.7% | 105,615 | $2.8M |
| Tidal Investments LLC | 0.01% | Add +0.7% | 105,615 | $2.8M |
| Platinum Investment Management Ltd. | 0.68% | No change | 105,184 | $2.7M |
| Manatuck Hill Partners, LLC | 0.87% | Add +150.0% | 100,000 | $2.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -6.7% | 106,398 | $2.6M |
| Kornitzer Capital Management Inc. | 0.05% | No change | 88,800 | $2.3M |
| Mackenzie Financial Corp. | 0.00% | Add +6.1% | 87,745 | $2.3M |
| Principal Financial Group Inc. | 0.00% | Add +8.2% | 84,990 | $2.2M |
| Y-Intercept (Hong Kong) Ltd | 0.04% | New | 83,455 | $2.2M |
| LMR Partners LLP | 0.02% | New | 82,500 | $2.2M |
| Ameriprise Financial Inc. | 0.00% | Add +10.8% | 82,264 | $2.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -74.5% | 81,359 | $2.1M |
| Vanguard Fiduciary Trust Co. | 0.00% | Reduce -5.1% | 80,120 | $2.1M |
| Stifel Financial Corp. | 0.00% | Add +0.6% | 77,214 | $2.0M |
| Franklin Resources Inc. | 0.00% | Reduce -1.5% | 76,528 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -0.4% | 75,066 | $2.0M |
| Swiss National Bank | 0.00% | No change | 74,200 | $1.9M |
| Martingale Asset Management L P | 0.05% | Add +123.7% | 73,282 | $1.9M |
| Two Sigma Investments, LP | 0.00% | New | 71,874 | $1.9M |
| Dana Investment Advisors, Inc. | 0.05% | Add +27.7% | 71,660 | $1.9M |
| Credit Agricole S A | 0.00% | Reduce -5.3% | 71,000 | $1.9M |
| Fisher Asset Management | 0.00% | Reduce -30.2% | 70,775 | $1.9M |
| Segall Bryant & Hamill, LLC | 0.02% | Add +46.2% | 66,836 | $1.7M |
| Verdad Advisers, LP | 1.67% | Reduce -19.4% | 66,688 | $1.7M |
| Susquehanna Portfolio Strategies, LLC | 0.03% | Reduce -34.6% | 65,248 | $1.7M |
| Campbell & CO Investment Adviser LLC | 0.08% | Add +10.9% | 60,874 | $1.6M |
| Royal Bank of Canada | 0.00% | Add +18.8% | 56,278 | $1.5M |
| Alliancebernstein L.P. | 0.00% | No change | 55,896 | $1.4M |
| Virtus Investment Advisers, LLC | 0.31% | Add +374.9% | 50,825 | $1.3M |
| Envestnet Asset Management Inc. | 0.00% | Add +20.4% | 48,675 | $1.3M |
| Russell Investments Group, Ltd. | 0.00% | Add +0.9% | 47,867 | $1.3M |
| Quantinno Capital Management LP | 0.00% | Add +20.2% | 47,642 | $1.2M |
| North Growth Management Ltd. | 0.15% | No change | 46,000 | $1.2M |
| Legal & General Group Plc | 0.00% | Add +64.7% | 43,160 | $1.1M |
| Victory Capital Management Inc. | 0.00% | Add +0.3% | 42,524 | $1.1M |
| Marshall Wace, LLP | 0.00% | Add +27.1% | 40,948 | $1.1M |
| O'shaughnessy Asset Management, LLC | 0.00% | Add +6.5% | 39,534 | $1.0M |
| T. Rowe Price Associates Inc. | 0.00% | Add +8.4% | 38,486 | $1.0M |
| California State Teachers Retirement System | 0.00% | Add +0.9% | 37,744 | $987K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -13.7% | 36,922 | $965K |
| Tudor Investment Corporation | 0.00% | Reduce -1.1% | 36,471 | $953K |
| HighTower Advisors, LLC | 0.00% | Reduce -0.5% | 36,100 | $944K |
| Persistent Asset Partners Ltd | 0.30% | No change | 35,935 | $939K |
| HighVista Strategies LLC | 0.20% | Reduce -0.2% | 34,013 | $889K |
| Commonwealth Equity Services, LLC | 0.00% | Add +23.1% | 32,052 | $838K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -2.2% | 30,886 | $807K |
| Creative Planning | 0.00% | Reduce -8.2% | 29,731 | $777K |
| SBI Okasan Asset Management Co.Ltd. | 0.03% | No change | 32,000 | $771K |
| MetLife Investment Management, LLC | 0.00% | Reduce -6.0% | 27,884 | $729K |
| Massachusetts Financial Services Co. | 0.00% | Add +1.2% | 27,670 | $723K |
| STRS Ohio | 0.00% | Reduce -12.0% | 26,500 | $693K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | No change | 26,279 | $687K |
| Brevan Howard Capital Management LP | 0.01% | New | 25,956 | $678K |
| Jump Financial, LLC | 0.01% | New | 25,608 | $669K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -36.1% | 25,162 | $658K |
| Ritholtz Wealth Management | 0.01% | No change | 24,243 | $634K |
| BNP Paribas Financial Markets | 0.00% | Reduce -17.4% | 23,229 | $607K |
| Duncan Williams Asset Management, LLC | 0.13% | No change | 22,095 | $578K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -7.7% | 21,578 | $564K |
| Barclays PLC | 0.00% | Add +12.1% | 20,603 | $539K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | Add +62.8% | 19,435 | $508K |
| Simplex Trading, LLC | 0.01% | Add +1354.4% | 19,431 | $508K |
| BetterWealth, LLC | 0.09% | New | 18,622 | $487K |
| Bank of Montreal | 0.00% | Add +5.4% | 18,416 | $481K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -54.0% | 18,267 | $477K |
| Jupiter Topco LLC | 0.00% | — | 18,200 | $476K |
| Susquehanna Fundamental Investments, LLC | 0.01% | New | 18,185 | $475K |
| Jane Street Group, LLC | 0.00% | Reduce -92.3% | 17,437 | $456K |
| New York State Common Retirement Fund | 0.00% | No change | 17,371 | $454K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -43.1% | 17,310 | $452K |
| Squarepoint Ops LLC | 0.00% | Reduce -80.5% | 16,200 | $423K |
| HSBC Holdings PLC | 0.00% | Reduce -58.7% | 15,588 | $421K |
| Vinva Investment Management Ltd | 0.00% | Reduce -50.3% | 11,983 | $420K |
| Jackson Creek Investment Advisors LLC | 0.14% | Reduce -0.3% | 18,648 | $409K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,340 | $401K |
| Agf Management Ltd. | 0.00% | No change | 15,000 | $392K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 13,702 | $358K |
| Intech Investment Management LLC | 0.00% | Reduce -4.8% | 11,935 | $312K |
| State of New Jersey Common Pension Fund D | 0.00% | Reduce -6.8% | 11,923 | $312K |
| Janney Montgomery Scott LLC | 0.00% | Add +3.3% | 11,865 | $310K |
| China Universal Asset Management Co., Ltd. | 0.02% | Reduce -12.5% | 11,622 | $304K |
| James Investment Research, Inc. | 0.03% | No change | 10,925 | $286K |
| Ewing Morris & Co. Investment Partners Ltd. | 0.15% | No change | 10,850 | $284K |
| Arizona State Retirement System | 0.00% | Reduce -1.0% | 10,175 | $266K |
| Jain Global LLC | 0.00% | New | 10,010 | $262K |
| PSP Research LLC | 0.14% | No change | 10,000 | $261K |
| Mitsubishi UFJ Trust & Banking Corp | 0.00% | New | 9,569 | $250K |
| Voya Investment Management LLC | 0.00% | Add +3.8% | 9,334 | $244K |
| Vanguard Investments Australia, Ltd. | 0.00% | No change | 8,803 | $230K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +3.0% | 8,762 | $225K |
| ProShare Advisors LLC | 0.00% | Reduce -19.1% | 8,557 | $224K |
| Inceptionr LLC | 0.05% | New | 8,313 | $217K |
| Magnetar Financial LLC | 0.00% | New | 8,292 | $217K |
| KLP Kapitalforvaltning As | 0.00% | No change | 8,000 | $209K |
| Prudential Financial Inc. | 0.00% | Reduce -63.9% | 7,940 | $208K |
| SG Americas Securities, LLC | 0.00% | Reduce -39.4% | 6,321 | $165K |
| Vanguard Global Advisers, LLC | 0.00% | No change | 5,459 | $143K |
| Northwest & Ethical Investments L.P. | 0.00% | Reduce -62.2% | 4,630 | $112K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,164 | $109K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 3,843 | $94K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -16.3% | 3,266 | $85K |
| Arax Advisory Partners | 0.00% | New | 2,998 | $78K |
| State of Wyoming | 0.01% | Reduce -83.7% | 2,792 | $73K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -51.3% | 2,373 | $62K |
| Asset Management One Co., Ltd. | 0.00% | New | 1,659 | $43K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -5.7% | 1,585 | $41K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 1,439 | $37K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +506.0% | 1,309 | $34K |
| Eurizon Capital SGR S.p.A. | 0.00% | New | 1,321 | $32K |
| GAMMA Investing LLC | 0.00% | Add +1.6% | 1,114 | $29K |
| Optiver Holding B.V. | 0.00% | Add +8.5% | 1,039 | $27K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 971 | $25K |
| Nykredit A/S | 0.00% | — | 966 | $25K |
| Lanark Financial, Inc. | 0.00% | Add +54.4% | 962 | $25K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -9.0% | 898 | $23K |
| Osaic Holdings, Inc. | 0.00% | No change | 882 | $23K |
| Jones Financial Companies LLLP | 0.00% | Add +80.0% | 837 | $20K |
| Freestone Grove Partners LP | 0.00% | Reduce -95.0% | 648 | $17K |
| National Bank of Canada | 0.00% | Add +4.9% | 581 | $15K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 570 | $15K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -50.5% | 481 | $13K |
| UMB Bank, n.a. | 0.00% | Reduce -0.4% | 464 | $12K |
| Huntington National Bank | 0.00% | Add +34.1% | 460 | $12K |
| Inspire Investing, LLC | 0.00% | New | 332 | $9K |
| Parallel Advisors, LLC | 0.00% | Reduce -6.5% | 329 | $9K |
| US Bancorp \de | 0.00% | Reduce -10.5% | 315 | $8K |
| SBI Securities Co., Ltd. | 0.00% | Add +2736.4% | 312 | $8K |
| Quarry LP | 0.00% | New | 210 | $5K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -14.2% | 187 | $5K |
| Sterling Capital Management LLC | 0.00% | Reduce -49.1% | 165 | $4K |
| Fortitude Family Office, LLC | 0.00% | New | 116 | $3K |
| Allworth Financial LP | 0.00% | Reduce -0.9% | 108 | $3K |
| IFP Advisors, Inc | 0.00% | No change | 96 | $3K |
| HighMark Wealth Management LLC | 0.00% | No change | 80 | $2K |
| Rothschild Investment LLC | 0.00% | No change | 80 | $2K |
| SJS Investment Consulting Inc. | 0.00% | New | 77 | $2K |
| Kilter Group LLC | 0.00% | No change | 66 | $2K |
| Bare Financial Services, Inc | 0.00% | No change | 64 | $2K |
| Rockefeller Capital Management L.P. | 0.00% | No change | 61 | $2K |
| True Wealth Design, LLC | 0.00% | No change | 58 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 51 | $1K |
| Versant Capital Management, Inc | 0.00% | No change | 45 | $1K |
| Covestor Ltd | 0.00% | Add +42.9% | 40 | $1K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -47.4% | 30 | $784 |
| International Assets Investment Management, LLC | 0.00% | No change | 25 | $643 |
| Essential Partners LLC | 0.00% | No change | 12 | $314 |
| Smartleaf Asset Management LLC | 0.00% | No change | 12 | $289 |
| Clearstead Advisors, LLC | 0.00% | New | 6 | $157 |
| Larson Financial Group LLC | 0.00% | No change | 6 | $157 |
| Silver Grove Financial Group, Inc. | 0.00% | New | 4 | $105 |
| Hughes Financial Services, LLC | 0.00% | Reduce -25.0% | 3 | $78 |
"% of holder's portfolio" is ZYME's weight in each manager's 13F, not the share of Zymeworks Inc. the manager owns.