Deep Track Capital, LP

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), Deep Track Capital, LP reported 56 stock positions worth $3.6 billion. Its top holding was Guardant Health (GH) at 7.2% of the portfolio, followed by Ionis Pharmaceuticals (IONS, 7.0%) and Cytokinetics (CYTK, 6.6%). Compared with Q2 2025, it opened 12 new positions, sold out of 21, added to 12 and reduced 21. The biggest buy was Cytokinetics (CYTK, shares +18%) and the biggest sale an exit from Insmed (INSM).

Most Recent 13F
Q2 2026
Location
GREENWICH, CT
CIK
0001856083
Portfolio Value
$3.6B (Q3 2025)
SEC Filing
0001856083-25-000006 ↗ filed Nov 14, 2025

Holdings Value

0$2.0B$4.0B$6.0B$8.0B Q1 2024: $3.5B Q1 2024 Q2 2024: $3.3B Q2 2024 Q3 2024: $3.1B Q3 2024 Q4 2024: $2.7B Q4 2024 Q1 2025: $3.1B Q1 2025 Q2 2025: $3.1B Q2 2025 Q3 2025: $3.6B $3.6B Q3 2025 Q4 2025: $4.4B Q4 2025 Q1 2026: $4.8B Q1 2026 Q2 2026: $6.8B Q2 2026

Holdings 56 stocks · $3.6B

GH Guardant Health Inc. 7.24% 4,154,086 $259.5M Reduce -2.3%
IONS Ionis Pharmaceuticals Inc. 6.95% 3,808,144 $249.1M Reduce -22.1%
CYTK Cytokinetics Inc. 6.60% 4,300,000 $236.3M Add +17.8%
AKRO Akero Therapeutics Inc. 5.30% 4,000,978 $190.0M Add +31.5%
APLS Apellis Pharmaceuticals Inc. 5.05% 8,000,382 $181.0M Add +14.3%
TARS Tarsus Pharmaceuticals Inc. 4.98% 3,000,000 $178.3M Add +71.4%
IMVT Immunovant Inc. 4.38% 9,728,845 $156.8M Add +2.4%
DVAX Dynavax Technologies Corp. 4.36% 15,726,349 $156.2M Reduce -11.6%
OCUL Ocular Therapeutix Inc. 3.89% 11,932,137 $139.5M Reduce -16.5%
ETNB 89BIO Inc. 3.84% 9,356,171 $137.5M Reduce -1.5%
GPCR Structure Therapeutics Inc. 3.29% 4,215,811 $118.0M Reduce -17.9%
VRDN Viridian Therapeutics Inc. 3.24% 5,380,449 $116.1M No change
PTGX Protagonist Therapeutics Inc. 3.18% 1,715,691 $114.0M Reduce -47.1%
AXSM Axsome Therapeutics Inc. 3.05% 900,000 $109.3M Add +12.3%
PCVX Vaxcyte Inc. 3.02% 3,000,000 $108.1M Add +39.5%
MAZE Maze Therapeutics Inc. 2.86% 3,948,910 $102.4M No change
IMCR Immunocore Holdings PLC-ADR 1.82% 1,800,000 $65.4M No change
BBIO Bridgebio Pharma Inc. 1.74% 1,200,000 $62.3M Add +33.3%
GERN Geron Corp. 1.57% 41,096,522 $56.3M Reduce -4.4%
TERN Terns Pharmaceuticals Inc. 1.57% 7,495,000 $56.3M No change
NRIX Nurix Therapeutics Inc. 1.56% 6,057,024 $56.0M Reduce -0.1%
MBX MBX Biosciences Inc. 1.54% 3,150,000 $55.1M Add +43.9%
EXAS Exact Sciences Corp. 1.53% 1,000,000 $54.7M New
LBRX LB Pharmaceuticals Inc. 1.48% 3,352,804 $52.9M New
CLDX Celldex Therapeutics Inc. 1.44% 2,000,000 $51.7M No change
ORKA Oruka Therapeutics Inc. 1.42% 2,654,781 $51.1M Add +38.4%
XENE Xenon Pharmaceuticals Inc. 1.34% 1,200,000 $48.2M Reduce -11.1%
CMPS Compass Pathways PLC 1.26% 7,859,648 $45.0M Reduce -11.0%
ANIP Ani Pharmaceuticals Inc. 1.15% 450,000 $41.2M Reduce -35.7%
BCAX Bicara Therapeutics Inc. 1.07% 2,426,657 $38.3M No change
OLMA Olema Pharmaceuticals Inc. 0.95% 3,470,172 $34.0M Add +0.8%
CDTX Cidara Therapeutics Inc. 0.80% 300,000 $28.7M Add +20.0%
QURE Uniqure NV 0.79% 483,092 $28.2M New
DYN Dyne Therapeutics Inc. 0.71% 2,000,000 $25.3M New
JBIO Jade Biosciences Inc. 0.55% 2,279,892 $19.7M Reduce -9.1%
RAPT Rapt Therapeutics Inc. 0.54% 751,422 $19.4M No change
GHRS GH Research PLC 0.50% 1,250,000 $17.9M Reduce -37.5%
MIND MEDICINE MINDMED INC 0.49% 1,500,000 $17.7M Reduce -40.0%
ENGN Engene Holdings Inc. 0.43% 2,239,353 $15.3M Reduce -50.9%
GMAB Genmab A/S -SP ADR 0.41% 481,267 $14.8M New
TNGX Tango Therapeutics Inc. 0.34% 1,454,562 $12.2M New
CNTX Context Therapeutics Inc. 0.20% 7,419,355 $7.2M No change
IMA Imagenebio Inc. 0.20% 878,516 $7.2M New
XNCR Xencor Inc. 0.18% 549,439 $6.4M No change
HELP Cybin Inc. 0.16% 1,000,000 $5.9M Reduce -34.6%
CRMD Cormedix Inc. 0.16% 500,000 $5.8M New
PEPG Pepgen Inc. 0.15% 1,200,000 $5.5M New
CBIO Crescent Biopharma Inc. 0.15% 453,686 $5.4M No change
ALGS Aligos Therapeutics Inc. 0.12% 444,110 $4.4M No change
AUTL Autolus Therapeutics PLC 0.12% 2,568,613 $4.2M Reduce -84.8%
XFOR X4 Pharmaceuticals Inc. 0.11% 1,122,484 $3.8M New
ACAD Acadia Pharmaceuticals Inc. 0.06% 105,085 $2.2M New
AVTX Avalo Therapeutics Inc. 0.05% 144,600 $1.8M Reduce -74.5%
BMRN Biomarin Pharmaceutical Inc. 0.04% 24,856 $1.3M New
ZURA Zura Bio Ltd. 0.03% 259,014 $1.1M Reduce -85.0%
CLYM Climb Bio Inc. 0.03% 509,789 $1.0M Reduce -51.0%

Portfolio Sells Q2 2025 → Q3 2025

INSM Insmed Inc. Sold out 0.00% −5.66
PTGX Protagonist Therapeutics Inc. Reduce -47.1% 3.18% −2.59
RARE Ultragenyx Pharmaceutical Inc. Sold out 0.00% −1.58
DNTH Dianthus Therapeutics Inc. Sold out 0.00% −1.34
DVAX Dynavax Technologies Corp. Reduce -11.6% 4.36% −1.32
AUTL Autolus Therapeutics PLC Reduce -84.8% 0.12% −1.12
MTSR Metsera Inc. Sold out 0.00% −1.00
TECX Tectonic Therapeutic Inc. Sold out 0.00% −0.90
ABVX Abivax SA-ADR Sold out 0.00% −0.86
NRIX Nurix Therapeutics Inc. Reduce -0.1% 1.56% −0.66
UPB Upstream Bio Inc. Sold out 0.00% −0.51
MRUS Merus NV Sold out 0.00% −0.47
GERN Geron Corp. Reduce -4.4% 1.57% −0.38
OCUL Ocular Therapeutix Inc. Reduce -16.5% 3.89% −0.37
ANIP Ani Pharmaceuticals Inc. Reduce -35.7% 1.15% −0.32
GHRS GH Research PLC Reduce -37.5% 0.50% −0.28
BCYC Bicycle Therapeutics PLC-ADR Sold out 0.00% −0.27
JBIO Jade Biosciences Inc. Reduce -9.1% 0.55% −0.26
HELP Cybin Inc. Reduce -34.6% 0.16% −0.25
CNTA Centessa Pharmaceuticals Ltd. Sold out 0.00% −0.21
NVAX Novavax Inc. Sold out 0.00% −0.20
IVVD Invivyd Inc. Sold out 0.00% −0.20
PLRX Pliant Therapeutics Inc. Sold out 0.00% −0.15
SRPT Sarepta Therapeutics Inc. Sold out 0.00% −0.14
INO Inovio Pharmaceuticals Inc. Sold out 0.00% −0.13
GPCR Structure Therapeutics Inc. Reduce -17.9% 3.29% −0.13
KRRO Korro Bio Inc. Sold out 0.00% −0.11
IKENA ONCOLOGY INC Sold out 0.00% −0.11
ENGN Engene Holdings Inc. Reduce -50.9% 0.43% −0.11
SYRE Spyre Therapeutics Inc. Sold out 0.00% −0.11
SEPN Septerna Inc. Sold out 0.00% −0.04
AVTX Avalo Therapeutics Inc. Reduce -74.5% 0.05% −0.04
RAPP Rapport Therapeutics Inc. Sold out 0.00% −0.04
MIND MEDICINE MINDMED INC Reduce -40.0% 0.49% −0.03
ZURA Zura Bio Ltd. Reduce -85.0% 0.03% −0.03
OKUR Onkure Therapeutics Inc. Class A Sold out 0.00% −0.01
XENE Xenon Pharmaceuticals Inc. Reduce -11.1% 1.34% −0.01
CLYM Climb Bio Inc. Reduce -51.0% 0.03% −0.01
GH Guardant Health Inc. Reduce -2.3% 7.24% +0.13
CMPS Compass Pathways PLC Reduce -11.0% 1.26% +0.46
IONS Ionis Pharmaceuticals Inc. Reduce -22.1% 6.95% +0.74
ETNB 89BIO Inc. Reduce -1.5% 3.84% +0.84

Portfolio Buys Q2 2025 → Q3 2025

CYTK Cytokinetics Inc. Add +17.8% 6.60% +2.72
TARS Tarsus Pharmaceuticals Inc. Add +71.4% 4.98% +2.70
EXAS Exact Sciences Corp. New 1.53% +1.53
LBRX LB Pharmaceuticals Inc. New 1.48% +1.48
APLS Apellis Pharmaceuticals Inc. Add +14.3% 5.05% +1.16
QURE Uniqure NV New 0.79% +0.79
PCVX Vaxcyte Inc. Add +39.5% 3.02% +0.77
MBX MBX Biosciences Inc. Add +43.9% 1.54% +0.74
ORKA Oruka Therapeutics Inc. Add +38.4% 1.42% +0.73
DYN Dyne Therapeutics Inc. New 0.71% +0.71
BBIO Bridgebio Pharma Inc. Add +33.3% 1.74% +0.49
OLMA Olema Pharmaceuticals Inc. Add +0.8% 0.95% +0.48
GMAB Genmab A/S -SP ADR New 0.41% +0.41
CDTX Cidara Therapeutics Inc. Add +20.0% 0.80% +0.41
AXSM Axsome Therapeutics Inc. Add +12.3% 3.05% +0.36
TNGX Tango Therapeutics Inc. New 0.34% +0.34
IMA Imagenebio Inc. New 0.20% +0.20
CRMD Cormedix Inc. New 0.16% +0.16
PEPG Pepgen Inc. New 0.15% +0.15
XFOR X4 Pharmaceuticals Inc. New 0.11% +0.11
AKRO Akero Therapeutics Inc. Add +31.5% 5.30% +0.08
ACAD Acadia Pharmaceuticals Inc. New 0.06% +0.06
BMRN Biomarin Pharmaceutical Inc. New 0.04% +0.04
IMVT Immunovant Inc. Add +2.4% 4.38% −0.51

Options Activity Q2 2025 → Q3 2025

SRPT Sarepta Therapeutics Inc. put Sold out 450,000 $7.7Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 66$6.8BGH, IMVT, GPCR, PCVX, ALNY
Q1 2026 62$4.8BGH, IMVT, TARS, PCVX, GPCR
Q4 2025 53$4.4BIMVT, GH, GPCR, TARS, DVAX
Q3 2025 56$3.6BGH, IONS, CYTK, AKRO, APLS
Q2 2025 65$3.1BGH, IONS, PTGX, DVAX, INSM
Q1 2025 69$3.1BITCI, GH, DVAX, IMVT, PTGX
Q4 2024 61$2.7BDVAX, GH, ITCI, IMVT, APLS
Q3 2024 69$3.1BARGX, DVAX, GH, APLS, IMVT
Q2 2024 67$3.3BAMGN, ARGX, AXSM, DYN, SWTX
Q1 2024 65$3.5BSWTX, AMGN, APGE, INSM, DYN