Diadema Partners LP

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Diadema Partners LP reported 86 stock positions worth $242.2 million. Its top holding was Bridgebio Pharma Inc. (bbio 1.75 03/01/31) at 7.7% of the portfolio, followed by Viking Therapeutics (VKTX, 7.1%) and United Therapeutics (UTHR, 6.7%). Compared with Q4 2025, it opened 43 new positions, sold out of 30, added to 26 and reduced 17. The biggest buy was a new position in Bridgebio Pharma Inc. (bbio 1.75 03/01/31) and the biggest sale an exit from Regeneron Pharmaceuticals (REGN).

Most Recent 13F
Q2 2026
Location
MORRISTOWN, NJ
CIK
0002026172
Portfolio Value
$242.2M (Q1 2026)
SEC Filing
0001892688-26-000076 ↗ filed May 15, 2026

Holdings Value

0$100.0M$200.0M$300.0M Q4 2024: $88.7M Q4 2024 Q1 2025: $125.1M Q1 2025 Q2 2025: $160.8M Q2 2025 Q3 2025: $143.6M Q3 2025 Q4 2025: $167.9M Q4 2025 Q1 2026: $242.2M $242.2M Q1 2026 Q2 2026: $264.6M Q2 2026

Holdings 86 stocks · $242.2M

BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) 7.67% 250,000 $18.6M New
VKTX Viking Therapeutics Inc. 7.06% 525,181 $17.1M Add +55.9%
UTHR United Therapeutics Corp. 6.69% 27,303 $16.2M Add +173.0%
JNJ Johnson & Johnson 5.43% 53,771 $13.1M Reduce -19.1%
COGT Cogent Biosciences Inc. 5.13% 322,764 $12.4M Add +144.8%
JAZZ Jazz Pharmaceuticals PLC 4.27% 54,755 $10.4M New
TERN Terns Pharmaceuticals Inc. 3.96% 181,752 $9.6M Reduce -47.5%
BMRN Biomarin Pharmaceutical Inc. 3.46% 148,229 $8.4M Add +1.3%
ABVX Abivax SA-ADR 3.39% 75,944 $8.2M Add +0.4%
RVMD Revolution Medicines Inc. 3.25% 80,872 $7.9M Add +118.5%
KOD Kodiak Sciences Inc. 3.04% 192,962 $7.4M New
INCY Incyte Corp. 3.03% 78,029 $7.3M New
TGTX TG Therapeutics Inc. 2.84% 206,928 $6.9M Add +67.8%
BBIO Bridgebio Pharma Inc. 2.62% 85,311 $6.3M Add +21.9%
IMCR Immunocore Holdings PLC-ADR 2.41% 193,189 $5.8M Add +174.8%
LLY Eli Lilly & Co. 2.28% 6,000 $5.5M Add +200.0%
ABBV Abbvie Inc. 2.16% 24,058 $5.2M New
RCUS Arcus Biosciences Inc. 2.12% 238,142 $5.1M New
CRBP Corbus Pharmaceuticals Holdi 1.71% 439,957 $4.1M New
CRVS Corvus Pharmaceuticals Inc. 1.48% 244,811 $3.6M New
ZYME Zymeworks Inc. 1.47% 142,132 $3.6M New
GPCR Structure Therapeutics Inc. 1.44% 72,234 $3.5M New
GLUE Monte Rosa Therapeutics Inc. 1.27% 187,307 $3.1M Add +200.8%
TENX Tenax Therapeutics Inc. 1.19% 179,738 $2.9M Reduce -26.1%
HRMY Harmony Biosciences Holdings 1.07% 92,864 $2.6M Add +1138.2%
CAPR Capricor Therapeutics Inc. 0.99% 78,851 $2.4M Reduce -50.1%
EYPT Eyepoint Inc. 0.95% 178,545 $2.3M New
BCYC Bicycle Therapeutics PLC-ADR 0.91% 476,424 $2.2M New
INDV Indivior Pharmaceuticals Inc. 0.90% 71,376 $2.2M Add +312.1%
CLYM Climb Bio Inc. 0.81% 286,126 $2.0M New
IVA Inventiva SA - ADR 0.80% 352,399 $1.9M Add +5.4%
STTK Shattuck Labs Inc. 0.78% 293,664 $1.9M New
TARS Tarsus Pharmaceuticals Inc. 0.75% 25,942 $1.8M New
ALKS Alkermes PLC 0.73% 50,000 $1.8M New
MGNX Macrogenics Inc. 0.72% 600,000 $1.7M New
VRTX Vertex Pharmaceuticals Inc. 0.71% 3,840 $1.7M Reduce -61.6%
VYGR Voyager Therapeutics Inc. 0.68% 423,642 $1.6M New
PCVX Vaxcyte Inc. 0.60% 25,071 $1.5M Add +9.1%
RLMD Relmada Therapeutics Inc. 0.58% 200,842 $1.4M Reduce -48.4%
BIOA Bioage Labs Inc. 0.43% 60,000 $1.0M Reduce -77.9%
INO Inovio Pharmaceuticals Inc. 0.40% 562,665 $979K Add +5.4%
AYTU Aytu Biopharma Inc. 0.40% 353,077 $964K Add +15.5%
EQ Equillium Inc. 0.36% 433,844 $868K Add +24.9%
DNTH Dianthus Therapeutics Inc. 0.35% 10,000 $839K New
PHVS Pharvaris NV 0.34% 29,321 $828K New
ENTA Enanta Pharmaceuticals Inc. 0.34% 64,952 $820K Reduce -0.3%
REPL Replimune Group Inc. 0.32% 100,660 $770K Reduce -56.4%
XERS Xeris Biopharma Holdings Inc. 0.32% 132,746 $770K Reduce -22.2%
LRMR Larimar Therapeutics Inc. 0.31% 166,637 $750K New
ANNX Annexon Inc. 0.30% 132,916 $736K Reduce -62.0%
RARE Ultragenyx Pharmaceutical Inc. 0.30% 35,144 $736K New
MLYS Mineralys Therapeutics Inc. 0.29% 26,347 $714K Add +5.4%
UNCY Unicycive Therapeutics Inc. 0.29% 106,083 $698K New
SPRB Spruce Biosciences Inc. 0.27% 10,000 $654K New
PHAT Phathom Pharmaceuticals Inc. 0.25% 54,650 $607K New
CELC Celcuity Inc. 0.25% 5,314 $607K New
CNTB Connect Biopharma Holdings L 0.22% 200,690 $526K New
NVO Novo-Nordisk A/S-Spons ADR 0.21% 14,577 $521K New
PTHS Pelthos Therapeutics Inc. 0.21% 24,773 $520K Reduce -0.9%
QURE Uniqure NV 0.21% 31,200 $510K Reduce -30.7%
MNKD Mannkind Corp. 0.19% 186,603 $457K Reduce -38.2%
MAZE Maze Therapeutics Inc. 0.18% 15,000 $448K New
URGN Urogen Pharma Ltd. 0.17% 23,155 $416K Add +6.2%
CORT Corcept Therapeutics Inc. 0.17% 10,000 $403K Reduce -89.7%
LPCN Lipocine Inc. 0.17% 50,000 $400K Reduce -80.8%
FHTX Foghorn Therapeutics Inc. 0.16% 79,944 $382K Add +161.0%
GHRS GH Research PLC 0.16% 26,836 $377K New
OCGN Ocugen Inc. 0.15% 200,000 $362K New
PRQR Proqr Therapeutics NV 0.12% 180,083 $292K Add +7.5%
EPRX Eupraxia Pharmaceuticals Inc. 0.12% 40,000 $290K New
PEPG Pepgen Inc. 0.11% 150,925 $267K New
TRVI Trevi Therapeutics Inc. 0.11% 21,663 $258K Reduce -77.7%
PGEN Precigen Inc. 0.09% 55,293 $214K New
UPB Upstream Bio Inc. 0.08% 21,609 $194K Add +5.4%
CMPS Compass Pathways PLC 0.07% 31,885 $176K New
PASG Passage Bio Inc. 0.06% 19,530 $153K New
TLPH Talphera Inc. 0.05% 153,563 $115K Add +12.2%
RCKT Rocket Pharmaceuticals Inc. 0.05% 30,579 $109K New
MNPR Monopar Therapeutics Inc. 0.04% 1,630 $89K New
VTGN Vistagen Therapeutics Inc. 0.02% 105,428 $60K Add +5.4%
RNA Atrium Therapeutics Inc. 0.01% 2,512 $34K New
CUE Cue Biopharma Inc. 0.01% 131,997 $30K New
ENTX Entera Bio Ltd. 0.01% 23,260 $26K New
PRTCY Puretech Health PLC - ADR 0.00% 7,924 $11K Add +6.5%
ELVN Enliven Therapeutics Inc. 0.00% 245 $10K New
SEPN Septerna Inc. 0.00% 202 $5K New

Options reported separately and not counted above: VRTX calls ($41.6M), LQDA calls ($25.0M), UTHR calls ($23.8M), VKTX calls ($21.5M), CAPR puts ($19.0M), APGE calls ($18.7M), CYTK puts ($13.2M), RVMD puts ($12.2M), MRK puts ($12.0M), UTHR puts ($11.9M), ABVX puts ($11.1M), ABVX calls ($11.1M), and 46 more.

Portfolio Sells Q4 2025 → Q1 2026

REGN Regeneron Pharmaceuticals Sold out 0.00% −4.73
TERN Terns Pharmaceuticals Inc. Reduce -47.5% 3.96% −4.37
JNJ Johnson & Johnson Reduce -19.1% 5.43% −2.76
ANIP Ani Pharmaceuticals Inc. Sold out 0.00% −2.51
VRTX Vertex Pharmaceuticals Inc. Reduce -61.6% 0.71% −1.99
CORT Corcept Therapeutics Inc. Reduce -89.7% 0.17% −1.85
CAPR Capricor Therapeutics Inc. Reduce -50.1% 0.99% −1.73
BIOA Bioage Labs Inc. Reduce -77.9% 0.43% −1.70
IRWD Ironwood Pharmaceuticals Inc. Sold out 0.00% −1.37
CNTA Centessa Pharmaceuticals Ltd. Sold out 0.00% −1.34
ALNY Alnylam Pharmaceuticals Inc. Sold out 0.00% −1.26
PTGX Protagonist Therapeutics Inc. Sold out 0.00% −1.18
LPCN Lipocine Inc. Reduce -80.8% 0.17% −1.08
VTYX Ventyx Biosciences Inc. Sold out 0.00% −1.08
REPL Replimune Group Inc. Reduce -56.4% 0.32% −1.02
BCRX Biocryst Pharmaceuticals Inc. Sold out 0.00% −0.89
ARDX Ardelyx Inc. Sold out 0.00% −0.88
ASND Ascendis Pharma A/S Sold out 0.00% −0.87
MNKD Mannkind Corp. Reduce -38.2% 0.19% −0.83
RIGL Rigel Pharmaceuticals Inc. Sold out 0.00% −0.77
ANNX Annexon Inc. Reduce -62.0% 0.30% −0.74
SLNO Soleno Therapeutics Inc. Sold out 0.00% −0.74
PCRX Pacira Biosciences Inc. Sold out 0.00% −0.74
MPLT Maplight Therapeutics Inc. Sold out 0.00% −0.67
TRVI Trevi Therapeutics Inc. Reduce -77.7% 0.11% −0.62
PRTA Prothena Corp. PLC Sold out 0.00% −0.61
TENX Tenax Therapeutics Inc. Reduce -26.1% 1.19% −0.58
DSGN Design Therapeutics Inc. Sold out 0.00% −0.56
RLMD Relmada Therapeutics Inc. Reduce -48.4% 0.58% −0.54
XERS Xeris Biopharma Holdings Inc. Reduce -22.2% 0.32% −0.48
LQDA Liquidia Corp. Sold out 0.00% −0.45
EWTX Edgewise Therapeutics Inc. Sold out 0.00% −0.44
QURE Uniqure NV Reduce -30.7% 0.21% −0.43
VRDN Viridian Therapeutics Inc. Sold out 0.00% −0.39
VIR Vir Biotechnology Inc. Sold out 0.00% −0.36
LGND Ligand Pharmaceuticals Sold out 0.00% −0.34
STOK Stoke Therapeutics Inc. Sold out 0.00% −0.32
IMNM Immunome Inc. Sold out 0.00% −0.29
ENTA Enanta Pharmaceuticals Inc. Reduce -0.3% 0.34% −0.27
PTHS Pelthos Therapeutics Inc. Reduce -0.9% 0.21% −0.25
PALI Palisade Bio Inc. Sold out 0.00% −0.23
AARD Aardvark Therapeutics Inc. Sold out 0.00% −0.12
NEUP Neuphoria Therapeutics Inc. Sold out 0.00% −0.12
PLRX Pliant Therapeutics Inc. Sold out 0.00% −0.11
ONC Beone Medicines Ltd.-ADR Sold out 0.00% −0.10
INBX Inhibrx Biosciences Inc. Sold out 0.00% −0.06
EDSA Edesa Biotech Inc. Sold out 0.00% −0.05

Portfolio Buys Q4 2025 → Q1 2026

BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) New 7.67% +7.67
JAZZ Jazz Pharmaceuticals PLC New 4.27% +4.27
UTHR United Therapeutics Corp. Add +173.0% 6.69% +3.78
KOD Kodiak Sciences Inc. New 3.04% +3.04
INCY Incyte Corp. New 3.03% +3.03
COGT Cogent Biosciences Inc. Add +144.8% 5.13% +2.34
ABBV Abbvie Inc. New 2.16% +2.16
RCUS Arcus Biosciences Inc. New 2.12% +2.12
CRBP Corbus Pharmaceuticals Holdi New 1.71% +1.71
RVMD Revolution Medicines Inc. Add +118.5% 3.25% +1.49
CRVS Corvus Pharmaceuticals Inc. New 1.48% +1.48
ZYME Zymeworks Inc. New 1.47% +1.47
GPCR Structure Therapeutics Inc. New 1.44% +1.44
LLY Eli Lilly & Co. Add +200.0% 2.28% +1.00
IMCR Immunocore Holdings PLC-ADR Add +174.8% 2.41% +0.95
EYPT Eyepoint Inc. New 0.95% +0.95
BCYC Bicycle Therapeutics PLC-ADR New 0.91% +0.91
HRMY Harmony Biosciences Holdings Add +1138.2% 1.07% +0.91
CLYM Climb Bio Inc. New 0.81% +0.81
STTK Shattuck Labs Inc. New 0.78% +0.78
TARS Tarsus Pharmaceuticals Inc. New 0.75% +0.75
ALKS Alkermes PLC New 0.73% +0.73
MGNX Macrogenics Inc. New 0.72% +0.72
GLUE Monte Rosa Therapeutics Inc. Add +200.8% 1.27% +0.69
VYGR Voyager Therapeutics Inc. New 0.68% +0.68
TGTX TG Therapeutics Inc. Add +67.8% 2.84% +0.65
INDV Indivior Pharmaceuticals Inc. Add +312.1% 0.90% +0.53
DNTH Dianthus Therapeutics Inc. New 0.35% +0.35
PHVS Pharvaris NV New 0.34% +0.34
LRMR Larimar Therapeutics Inc. New 0.31% +0.31
RARE Ultragenyx Pharmaceutical Inc. New 0.30% +0.30
UNCY Unicycive Therapeutics Inc. New 0.29% +0.29
SPRB Spruce Biosciences Inc. New 0.27% +0.27
PHAT Phathom Pharmaceuticals Inc. New 0.25% +0.25
CELC Celcuity Inc. New 0.25% +0.25
CNTB Connect Biopharma Holdings L New 0.22% +0.22
NVO Novo-Nordisk A/S-Spons ADR New 0.21% +0.21
MAZE Maze Therapeutics Inc. New 0.18% +0.18
GHRS GH Research PLC New 0.16% +0.16
OCGN Ocugen Inc. New 0.15% +0.15
EPRX Eupraxia Pharmaceuticals Inc. New 0.12% +0.12
PEPG Pepgen Inc. New 0.11% +0.11
PGEN Precigen Inc. New 0.09% +0.09
CMPS Compass Pathways PLC New 0.07% +0.07
PASG Passage Bio Inc. New 0.06% +0.06
FHTX Foghorn Therapeutics Inc. Add +161.0% 0.16% +0.06
RCKT Rocket Pharmaceuticals Inc. New 0.05% +0.05
EQ Equillium Inc. Add +24.9% 0.36% +0.04
MNPR Monopar Therapeutics Inc. New 0.04% +0.04
RNA Atrium Therapeutics Inc. New 0.01% +0.01

Options Activity Q4 2025 → Q1 2026

VRTX Vertex Pharmaceuticals Inc. call Add +5.4% 93,100 $41.6M
XBI SS SPDR S&P Biotech ETF put Sold out 250,000 $30.5Mbefore exit
PRAX Praxis Precision Medicines I put Sold out 100,600 $29.7Mbefore exit
LQDA Liquidia Corp. call New 662,100 $25.0M
UTHR United Therapeutics Corp. call New 40,200 $23.8M
RNAM Avidity Biosciences Inc. call Sold out 328,000 $23.7Mbefore exit
VKTX Viking Therapeutics Inc. call Reduce -4.3% 659,200 $21.5M
CAPR Capricor Therapeutics Inc. put Add +211.7% 623,400 $19.0M
APGE Apogee Therapeutics Inc. call Add +5.4% 222,500 $18.7M
QQQ Invesco QQQ Trust Series 1 put Sold out 30,000 $18.4Mbefore exit
JAZZ Jazz Pharmaceuticals PLC call Sold out 105,300 $17.9Mbefore exit
BBIO Bridgebio Pharma Inc. put Sold out 200,000 $15.3Mbefore exit
GPCR Structure Therapeutics Inc. call Sold out 191,700 $13.3Mbefore exit
CYTK Cytokinetics Inc. put New 200,000 $13.2M
RVMD Revolution Medicines Inc. put New 125,500 $12.2M
MRK Merck & Co. Inc. put New 100,000 $12.0M
UTHR United Therapeutics Corp. put New 20,000 $11.9M
VKTX Viking Therapeutics Inc. put Sold out 316,700 $11.1Mbefore exit
ABVX Abivax SA-ADR put New 100,000 $11.1M
ABVX Abivax SA-ADR call New 100,000 $11.1M
BBIO Bridgebio Pharma Inc. call Sold out 139,600 $10.7Mbefore exit
JNJ Johnson & Johnson call Sold out 50,000 $10.3Mbefore exit
CAPR Capricor Therapeutics Inc. call Add +5.4% 329,300 $10.0M
INCY Incyte Corp. put Add +5.4% 105,400 $9.9M
KOD Kodiak Sciences Inc. put New 246,900 $9.4M
ROIV Roivant Sciences Ltd. put Add +5.4% 335,800 $9.3M
INSM Insmed Inc. call Sold out 52,800 $9.2Mbefore exit
IONS Ionis Pharmaceuticals Inc. call Sold out 106,200 $8.4Mbefore exit
MRNA Moderna Inc. put New 159,400 $8.1M
INDV Indivior Pharmaceuticals Inc. call Sold out 220,300 $7.9Mbefore exit
EWTX Edgewise Therapeutics Inc. call New 212,500 $6.7M
OCUL Ocular Therapeutix Inc. call Sold out 545,200 $6.6Mbefore exit
CORT Corcept Therapeutics Inc. call New 158,500 $6.4M
ZYME Zymeworks Inc. call Sold out 240,600 $6.3Mbefore exit
GPCR Structure Therapeutics Inc. put New 127,500 $6.1M
CRSP Crispr Therapeutics AG call Reduce -5.7% 106,300 $5.1M
QURE Uniqure NV put Reduce -0.9% 299,000 $4.9M
CORT Corcept Therapeutics Inc. put Sold out 134,800 $4.7Mbefore exit
QURE Uniqure NV call New 250,000 $4.1M
REGN Regeneron Pharmaceuticals call Sold out 5,000 $3.9Mbefore exit
REPL Replimune Group Inc. put New 459,900 $3.5M
CYTK Cytokinetics Inc. call New 50,000 $3.3M
MNKD Mannkind Corp. call Sold out 552,300 $3.1Mbefore exit
PCVX Vaxcyte Inc. call New 53,100 $3.1M
RXRX Recursion Pharmaceuticals-A call Sold out 741,900 $3.0Mbefore exit
TGTX TG Therapeutics Inc. put Sold out 100,000 $3.0Mbefore exit
NTLA Intellia Therapeutics Inc. put Sold out 316,900 $2.8Mbefore exit
GOSS Gossamer Bio Inc. call Sold out 877,100 $2.7Mbefore exit
BHVN Biohaven Ltd. call Add +58.5% 317,000 $2.7M
ABUS Arbutus Biopharma Corp. call Sold out 548,600 $2.6Mbefore exit

Showing the first 50 of 103.

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 77$264.6MUTHR, RVMD, ABVX, COGT, BMRN
Q1 2026 86$242.2MBRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31), VKTX, UTHR, JNJ, COGT
Q4 2025 73$167.9MTERN, JNJ, VKTX, ABVX, BMRN
Q3 2025 59$143.6MREGN, SLNO, BMRN, PCVX, INDV
Q2 2025 46$160.8MSLNO, AMGN, TGTX, NBIX, LLY
Q1 2025 43$125.1MREGN, LLY, JAZZ, TGTX, ARGX
Q4 2024 54$88.7MBMY, ABBV, TEVA, BPMC, RYTM