Integral Health Asset Management, LLC

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Integral Health Asset Management, LLC reported 70 stock positions worth $1.1 billion. Its top holding was Insmed (INSM) at 15.0% of the portfolio, followed by Boston Scientific (BSX, 5.5%) and Tenet Healthcare (THC, 4.5%). Compared with Q1 2025, it opened 18 new positions, sold out of 24, added to 24 and reduced 16. The biggest buy was a new position in Quest Diagnostics (DGX) and the biggest sale an exit from Gilead Sciences (GILD).

Most Recent 13F
Q2 2026
Location
New York, NY
CIK
0001773206
Portfolio Value
$1.1B (Q2 2025)
SEC Filing
0001172661-25-003253 ↗ filed Aug 14, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.0B Q1 2024 Q2 2024: $1.0B Q2 2024 Q3 2024: $849.4M Q3 2024 Q4 2024: $1.1B Q4 2024 Q1 2025: $902.7M Q1 2025 Q2 2025: $1.1B $1.1B Q2 2025 Q3 2025: $1.4B Q3 2025 Q4 2025: $2.0B Q4 2025 Q1 2026: $1.9B Q1 2026 Q2 2026: $2.4B Q2 2026

Holdings 70 stocks · $1.1B

INSM Insmed Inc. 15.04% 1,600,000 $161.0M Add +3.2%
BSX Boston Scientific Corp. 5.52% 550,000 $59.1M Reduce -15.4%
THC Tenet Healthcare Corp. 4.52% 275,000 $48.4M No change
EHC Encompass Health Corp. 3.67% 320,000 $39.2M Add +18.5%
MLYS Mineralys Therapeutics Inc. 3.41% 2,700,000 $36.5M Add +17.4%
CYTK Cytokinetics Inc. 3.09% 1,000,000 $33.0M Reduce -9.1%
BTSG Brightspring Health Services 2.75% 1,250,000 $29.5M Add +61.3%
VERA Vera Therapeutics Inc. 2.53% 1,150,000 $27.1M No change
DGX Quest Diagnostics Inc. 2.52% 150,000 $26.9M New
REGN Regeneron Pharmaceuticals 2.45% 50,000 $26.3M New
NVS Novartis AG-Sponsored ADR 2.26% 200,000 $24.2M Reduce -20.0%
CAH Cardinal Health Inc. 2.20% 140,000 $23.5M New
ELV Elevance Health Inc. 2.18% 60,000 $23.3M Reduce -7.7%
RDNT Radnet Inc. 2.13% 400,000 $22.8M Add +60.0%
FMS Fresenius Medical Care-ADR 2.00% 750,000 $21.4M Add +10.3%
LLY Eli Lilly & Co. 1.82% 25,000 $19.5M New
NBIX Neurocrine Biosciences Inc. 1.76% 150,000 $18.9M No change
QURE Uniqure NV 1.76% 1,350,000 $18.8M Add +8.0%
ALNY Alnylam Pharmaceuticals Inc. 1.68% 55,000 $17.9M Add +10.0%
DXCM Dexcom Inc. 1.63% 200,000 $17.5M Add +100.0%
CRL Charles River Laboratories 1.63% 115,000 $17.4M New
MDT Medtronic PLC 1.63% 200,000 $17.4M Reduce -33.3%
CVS CVS Health Corp. 1.61% 250,000 $17.2M Add +25.0%
PFE Pfizer Inc. 1.59% 700,000 $17.0M Add +133.3%
EW Edwards Lifesciences Corp. 1.46% 200,000 $15.6M Add +60.0%
GEHC GE Healthcare Technology 1.38% 200,000 $14.8M Add +33.3%
AZN Astrazeneca PLC-Spons ADR 1.31% 200,000 $14.0M New
EWTX Edgewise Therapeutics Inc. 1.22% 1,000,000 $13.1M Add +48.1%
ORIC Oric Pharmaceuticals Inc. 1.19% 1,250,000 $12.7M New
RVMD Revolution Medicines Inc. 1.12% 325,000 $12.0M Add +30.0%
ETNB 89BIO Inc. 0.96% 1,050,000 $10.3M No change
PEN Penumbra Inc. 0.96% 40,000 $10.3M Add +14.3%
MLTX Moonlake Immunotherapeutics 0.88% 200,000 $9.4M No change
INSP Inspire Medical Systems Inc. 0.85% 70,000 $9.1M Add +7.7%
ACHC Acadia Healthcare Co. Inc. 0.85% 400,000 $9.1M Add +60.0%
BEAM Beam Therapeutics Inc. 0.79% 500,000 $8.5M New
HOLX Hologic Inc. 0.76% 125,000 $8.1M New
TARS Tarsus Pharmaceuticals Inc. 0.76% 200,000 $8.1M No change
RZLT Rezolute Inc. 0.75% 1,800,000 $8.0M Add +260.0%
RYTM Rhythm Pharmaceuticals Inc. 0.71% 120,000 $7.6M New
BAX Baxter International Inc. 0.71% 250,000 $7.6M Reduce -50.0%
ABBV Abbvie Inc. 0.69% 40,000 $7.4M Reduce -33.3%
MCK McKesson Corp. 0.68% 10,000 $7.3M Reduce -16.7%
ROIV Roivant Sciences Ltd. 0.63% 600,000 $6.8M No change
IRTC Irhythm Holdings Inc. 0.58% 40,000 $6.2M New
A Agilent Technologies Inc. 0.55% 50,000 $5.9M New
RGNX Regenxbio Inc. 0.54% 700,000 $5.7M Reduce -24.3%
VRNA Verona Pharma Ltd. 0.53% 60,000 $5.7M Reduce -47.8%
ALHC Alignment Healthcare Inc. 0.52% 400,000 $5.6M Add +100.0%
ATYR Atyr Pharma Inc. 0.50% 1,050,000 $5.3M Add +50.0%
EXAS Exact Sciences Corp. 0.50% 100,000 $5.3M New
WAT Waters Corp. 0.49% 15,000 $5.2M Reduce -25.0%
GKOS Glaukos Corp. 0.48% 50,000 $5.2M New
ELAN Elanco Animal Health Inc. 0.47% 350,000 $5.0M New
COO The Cooper Cos Inc. 0.47% 70,000 $5.0M New
CRSP Crispr Therapeutics AG 0.45% 100,000 $4.9M Reduce -33.3%
TARA Protara Therapeutic Inc. 0.40% 1,400,000 $4.2M No change
BHVN Biohaven Ltd. 0.40% 300,000 $4.2M Add +71.4%
SANA Sana Biotechnology Inc. 0.38% 1,500,000 $4.1M Reduce -25.0%
RARE Ultragenyx Pharmaceutical Inc. 0.34% 100,000 $3.6M New
SRRK Scholar Rock Holding Corp. 0.33% 100,000 $3.5M Reduce -20.0%
NRIX Nurix Therapeutics Inc. 0.33% 310,000 $3.5M Add +12.7%
JSPR Jasper Therapeutics Inc. 0.31% 590,000 $3.3M Add +2.6%
CPRX Catalyst Pharmaceuticals Inc. 0.30% 150,000 $3.3M No change
ALKS Alkermes PLC 0.27% 100,000 $2.9M Reduce -33.3%
TERN Terns Pharmaceuticals Inc. 0.24% 700,000 $2.6M No change
RCUS Arcus Biosciences Inc. 0.23% 300,000 $2.4M New
OSCR Oscar Health Inc. Class A 0.20% 100,000 $2.1M Reduce -50.0%
TENX Tenax Therapeutics Inc. 0.09% 167,000 $962K No change
ANRO Alto Neuroscience Inc. 0.08% 400,000 $880K No change

Options reported separately and not counted above: CYTK calls ($16.5M), VKTX calls ($5.3M).

Portfolio Sells Q1 2025 → Q2 2025

GILD Gilead Sciences Inc. Sold out 0.00% −2.17
CYTK Cytokinetics Inc. Reduce -9.1% 3.09% −1.81
BSX Boston Scientific Corp. Reduce -15.4% 5.52% −1.75
ASND Ascendis Pharma A/S Sold out 0.00% −1.73
BPMC Blueprint Medicines Corp. Sold out 0.00% −1.42
MDT Medtronic PLC Reduce -33.3% 1.63% −1.36
KRYS Krystal Biotech Inc. Sold out 0.00% −1.20
BAX Baxter International Inc. Reduce -50.0% 0.71% −1.19
ELV Elevance Health Inc. Reduce -7.7% 2.18% −0.95
TEVA Teva Pharmaceutical-SP ADR Sold out 0.00% −0.85
MASI Masimo Corp. Sold out 0.00% −0.83
NVS Novartis AG-Sponsored ADR Reduce -20.0% 2.26% −0.83
ABBV Abbvie Inc. Reduce -33.3% 0.69% −0.70
BMY Bristol-Myers Squibb Co. Sold out 0.00% −0.68
IQV Iqvia Holdings Inc. Sold out 0.00% −0.59
PTCT PTC Therapeutics Inc. Sold out 0.00% −0.56
DYN Dyne Therapeutics Inc. Sold out 0.00% −0.52
LH Labcorp Holdings Inc. Sold out 0.00% −0.52
BDX Becton Dickinson and Co. Sold out 0.00% −0.51
CRNX Crinetics Pharmaceuticals Inc. Sold out 0.00% −0.46
GMED Globus Medical Inc. Class A Sold out 0.00% −0.41
BNTX Biontech SE-ADR Sold out 0.00% −0.40
BBIO Bridgebio Pharma Inc. Sold out 0.00% −0.38
CI The Cigna Group Sold out 0.00% −0.36
VSTM Verastem Inc. Sold out 0.00% −0.33
WAT Waters Corp. Reduce -25.0% 0.49% −0.33
RGEN Repligen Corp. Sold out 0.00% −0.28
ALKS Alkermes PLC Reduce -33.3% 0.27% −0.28
VRNA Verona Pharma Ltd. Reduce -47.8% 0.53% −0.28
ARWR Arrowhead Pharmaceuticals Inc. Sold out 0.00% −0.25
MCK McKesson Corp. Reduce -16.7% 0.68% −0.21
MREO Mereo Biopharma Group PL-ADR Sold out 0.00% −0.20
RGNX Regenxbio Inc. Reduce -24.3% 0.54% −0.20
CABA Cabaletta Bio Inc. Sold out 0.00% −0.13
SRRK Scholar Rock Holding Corp. Reduce -20.0% 0.33% −0.11
CRSP Crispr Therapeutics AG Reduce -33.3% 0.45% −0.11
OSCR Oscar Health Inc. Class A Reduce -50.0% 0.20% −0.09
PTN Palatin Technologies Inc. Sold out 0.00% −0.06
FATE Fate Therapeutics Inc. Sold out 0.00% −0.06
SANA Sana Biotechnology Inc. Reduce -25.0% 0.38% +0.01

Portfolio Buys Q1 2025 → Q2 2025

DGX Quest Diagnostics Inc. New 2.52% +2.52
REGN Regeneron Pharmaceuticals New 2.45% +2.45
CAH Cardinal Health Inc. New 2.20% +2.20
INSM Insmed Inc. Add +3.2% 15.04% +1.94
LLY Eli Lilly & Co. New 1.82% +1.82
CRL Charles River Laboratories New 1.63% +1.63
AZN Astrazeneca PLC-Spons ADR New 1.31% +1.31
BTSG Brightspring Health Services Add +61.3% 2.75% +1.20
ORIC Oric Pharmaceuticals Inc. New 1.19% +1.19
DXCM Dexcom Inc. Add +100.0% 1.63% +0.87
BEAM Beam Therapeutics Inc. New 0.79% +0.79
HOLX Hologic Inc. New 0.76% +0.76
RDNT Radnet Inc. Add +60.0% 2.13% +0.75
PFE Pfizer Inc. Add +133.3% 1.59% +0.74
RYTM Rhythm Pharmaceuticals Inc. New 0.71% +0.71
EHC Encompass Health Corp. Add +18.5% 3.67% +0.64
RZLT Rezolute Inc. Add +260.0% 0.75% +0.59
IRTC Irhythm Holdings Inc. New 0.58% +0.58
A Agilent Technologies Inc. New 0.55% +0.55
EXAS Exact Sciences Corp. New 0.50% +0.50
GKOS Glaukos Corp. New 0.48% +0.48
ELAN Elanco Animal Health Inc. New 0.47% +0.47
COO The Cooper Cos Inc. New 0.47% +0.47
EW Edwards Lifesciences Corp. Add +60.0% 1.46% +0.46
RARE Ultragenyx Pharmaceutical Inc. New 0.34% +0.34
QURE Uniqure NV Add +8.0% 1.76% +0.29
ATYR Atyr Pharma Inc. Add +50.0% 0.50% +0.26
RCUS Arcus Biosciences Inc. New 0.23% +0.23
ALNY Alnylam Pharmaceuticals Inc. Add +10.0% 1.68% +0.18
RVMD Revolution Medicines Inc. Add +30.0% 1.12% +0.14
FMS Fresenius Medical Care-ADR Add +10.3% 2.00% +0.13
ALHC Alignment Healthcare Inc. Add +100.0% 0.52% +0.11
CVS CVS Health Corp. Add +25.0% 1.61% +0.11
GEHC GE Healthcare Technology Add +33.3% 1.38% +0.04
JSPR Jasper Therapeutics Inc. Add +2.6% 0.31% +0.03
ACHC Acadia Healthcare Co. Inc. Add +60.0% 0.85% +0.01
NRIX Nurix Therapeutics Inc. Add +12.7% 0.33% −0.03
BHVN Biohaven Ltd. Add +71.4% 0.40% −0.07
PEN Penumbra Inc. Add +14.3% 0.96% −0.08
INSP Inspire Medical Systems Inc. Add +7.7% 0.85% −0.30
EWTX Edgewise Therapeutics Inc. Add +48.1% 1.22% −0.42
MLYS Mineralys Therapeutics Inc. Add +17.4% 3.41% −0.63

Options Activity Q1 2025 → Q2 2025

CYTK Cytokinetics Inc. call New 500,000 $16.5M
ACLX Arcellx Inc. call Sold out 200,000 $13.1Mbefore exit
XENE Xenon Pharmaceuticals Inc. put Sold out 200,000 $6.7Mbefore exit
EWTX Edgewise Therapeutics Inc. call Sold out 300,000 $6.6Mbefore exit
RNAM Avidity Biosciences Inc. put Sold out 200,000 $5.9Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 89$2.4BRVMD, INSM, CYTK, CVS, EWTX
Q1 2026 86$1.9BINSM, RVMD, CYTK, REGN, VERA
Q4 2025 84$2.0BINSM, RVMD, VERA, CYTK, REGN
Q3 2025 72$1.4BINSM, CYTK, THC, MLYS, VERA
Q2 2025 70$1.1BINSM, BSX, THC, EHC, MLYS
Q1 2025 76$902.7MINSM, BSX, CYTK, THC, MLYS
Q4 2024 81$1.1BINSM, THC, BSX, VERA, CYTK
Q3 2024 63$849.4MINSM, THC, BSX, CYTK, LBPH
Q2 2024 69$1.0BINSM, THC, CYTK, BSX, ELV
Q1 2024 76$1.0BTHC, BSX, VKTX, INSM, CYTK