Integral Health Asset Management, LLC

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), Integral Health Asset Management, LLC reported 63 stock positions worth $849.4 million. Its top holding was Insmed (INSM) at 12.5% of the portfolio, followed by Tenet Healthcare (THC, 10.4%) and Boston Scientific (BSX, 5.4%). Compared with Q2 2024, it opened 29 new positions, sold out of 35, added to 13 and reduced 14. The biggest buy was a new position in Inspire Medical Systems (INSP) and the biggest sale an exit from Elevance Health (ELV).

Most Recent 13F
Q2 2026
Location
New York, NY
CIK
0001773206
Portfolio Value
$849.4M (Q3 2024)
SEC Filing
0001172661-24-004870 ↗ filed Nov 14, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.0B Q1 2024 Q2 2024: $1.0B Q2 2024 Q3 2024: $849.4M $849.4M Q3 2024 Q4 2024: $1.1B Q4 2024 Q1 2025: $902.7M Q1 2025 Q2 2025: $1.1B Q2 2025 Q3 2025: $1.4B Q3 2025 Q4 2025: $2.0B Q4 2025 Q1 2026: $1.9B Q1 2026 Q2 2026: $2.4B Q2 2026

Holdings 63 stocks · $849.4M

INSM Insmed Inc. 12.46% 1,450,000 $105.8M Reduce -6.5%
THC Tenet Healthcare Corp. 10.37% 530,000 $88.1M Add +6.0%
BSX Boston Scientific Corp. 5.43% 550,000 $46.1M Reduce -15.4%
CYTK Cytokinetics Inc. 4.66% 750,000 $39.6M Reduce -25.0%
LBPH Longboard Pharmaceuticals Inc. 4.12% 1,050,000 $35.0M Reduce -4.5%
INSP Inspire Medical Systems Inc. 3.98% 160,000 $33.8M New
MDT Medtronic PLC 3.18% 300,000 $27.0M New
BPMC Blueprint Medicines Corp. 3.16% 290,000 $26.8M Reduce -14.7%
EHC Encompass Health Corp. 3.13% 275,000 $26.6M Reduce -8.3%
NVS Novartis AG-Sponsored ADR 2.71% 200,000 $23.0M Reduce -33.3%
ACLX Arcellx Inc. 2.70% 275,000 $23.0M No change
MRK Merck & Co. Inc. 2.67% 200,000 $22.7M Reduce -14.9%
VERA Vera Therapeutics Inc. 2.60% 500,000 $22.1M No change
DGX Quest Diagnostics Inc. 2.19% 120,000 $18.6M Add +20.0%
NARI Inari Medical Inc. 1.94% 400,000 $16.5M No change
RVMD Revolution Medicines Inc. 1.87% 350,000 $15.9M Add +7.7%
CRNX Crinetics Pharmaceuticals Inc. 1.80% 300,000 $15.3M Reduce -25.0%
RGNX Regenxbio Inc. 1.57% 1,275,000 $13.4M Add +34.2%
TARS Tarsus Pharmaceuticals Inc. 1.45% 375,000 $12.3M Reduce -36.4%
COO The Cooper Cos Inc. 1.43% 110,000 $12.1M New
KROS Keros Therapeutics Inc. 1.37% 200,000 $11.6M Add +135.3%
MLTX Moonlake Immunotherapeutics 1.31% 220,000 $11.1M No change
FMS Fresenius Medical Care-ADR 1.13% 450,000 $9.6M New
BRKR Bruker Corp. 1.10% 135,000 $9.3M Add +3.9%
BMY Bristol-Myers Squibb Co. 1.07% 175,000 $9.1M New
LLY Eli Lilly & Co. 1.04% 10,000 $8.9M No change
DXCM Dexcom Inc. 0.95% 120,000 $8.0M New
CPRX Catalyst Pharmaceuticals Inc. 0.94% 400,000 $8.0M Add +45.5%
SANA Sana Biotechnology Inc. 0.88% 1,800,000 $7.5M Add +50.0%
TFX Teleflex Inc. 0.87% 30,000 $7.4M Reduce -33.3%
BTSG Brightspring Health Services 0.86% 500,000 $7.3M New
CRSP Crispr Therapeutics AG 0.83% 150,000 $7.0M No change
ALNY Alnylam Pharmaceuticals Inc. 0.81% 25,000 $6.9M New
APLT Applied Therapeutics Inc. 0.80% 800,000 $6.8M New
JSPR Jasper Therapeutics Inc. 0.78% 350,000 $6.6M New
TNDM Tandem Diabetes Care Inc. 0.75% 150,000 $6.4M New
BNTX Biontech SE-ADR 0.70% 50,000 $5.9M New
QDEL Quidelortho Corp. 0.67% 125,000 $5.7M Reduce -16.7%
VRDN Viridian Therapeutics Inc. 0.67% 250,000 $5.7M New
EVH Evolent Health Inc. Class A 0.67% 200,000 $5.7M New
EXAS Exact Sciences Corp. 0.64% 80,000 $5.4M New
IQV Iqvia Holdings Inc. 0.56% 20,000 $4.7M New
TNYA Tenaya Therapeutics Inc. 0.54% 2,375,000 $4.6M Add +2.1%
TWST Twist Bioscience Corp. 0.53% 100,000 $4.5M New
NRIX Nurix Therapeutics Inc. 0.53% 200,000 $4.5M Add +33.3%
MLYS Mineralys Therapeutics Inc. 0.51% 356,000 $4.3M New
MREO Mereo Biopharma Group PL-ADR 0.48% 1,000,000 $4.1M Reduce -43.7%
RVTY Revvity Inc. 0.45% 30,000 $3.8M New
ETNB 89BIO Inc. 0.44% 500,000 $3.7M Add +11.1%
MYGN Myriad Genetics Inc. 0.40% 125,000 $3.4M New
FATE Fate Therapeutics Inc. 0.40% 975,000 $3.4M Add +14.7%
PLRX Pliant Therapeutics Inc. 0.40% 300,000 $3.4M New
NGNE Neurogene Inc. 0.35% 70,000 $2.9M No change
TERN Terns Pharmaceuticals Inc. 0.29% 300,000 $2.5M New
SRRK Scholar Rock Holding Corp. 0.26% 275,000 $2.2M Reduce -31.3%
CABA Cabaletta Bio Inc. 0.25% 450,000 $2.1M Add +5.9%
NTLA Intellia Therapeutics Inc. 0.24% 100,000 $2.1M New
QURE Uniqure NV 0.23% 400,000 $2.0M New
GEHC GE Healthcare Technology 0.22% 20,000 $1.9M New
STAA Staar Surgical Co. 0.22% 50,000 $1.9M New
TNGX Tango Therapeutics Inc. 0.18% 200,000 $1.5M New
RZLT Rezolute Inc. 0.14% 250,000 $1.2M New
KYTX Kyverna Therapeutics Inc. 0.12% 200,000 $978K New

Options reported separately and not counted above: VKTX calls ($15.8M), EWTX calls ($13.3M), CLDX calls ($10.2M).

Portfolio Sells Q2 2024 → Q3 2024

ELV Elevance Health Inc. Sold out 0.00% −4.31
HUM Humana Inc. Sold out 0.00% −2.79
UHS Universal Health Services-B Sold out 0.00% −2.39
BDX Becton Dickinson and Co. Sold out 0.00% −1.74
CI The Cigna Group Sold out 0.00% −1.65
KRYS Krystal Biotech Inc. Sold out 0.00% −1.55
ICLR Icon PLC Sold out 0.00% −1.40
EW Edwards Lifesciences Corp. Sold out 0.00% −1.38
TMO Thermo Fisher Scientific Inc. Sold out 0.00% −1.38
VKTX Viking Therapeutics Inc. Sold out 0.00% −1.32
AMGN Amgen Inc. Sold out 0.00% −1.24
IONS Ionis Pharmaceuticals Inc. Sold out 0.00% −1.19
MCK McKesson Corp. Sold out 0.00% −1.16
ITCI Intra-Cellular Therapies Inc. Sold out 0.00% −0.99
SNY Sanofi-ADR Sold out 0.00% −0.97
NBIX Neurocrine Biosciences Inc. Sold out 0.00% −0.96
GMED Globus Medical Inc. Class A Sold out 0.00% −0.85
OSCR Oscar Health Inc. Class A Sold out 0.00% −0.79
RGEN Repligen Corp. Sold out 0.00% −0.75
DNLI Denali Therapeutics Inc. Sold out 0.00% −0.75
CYTK Cytokinetics Inc. Reduce -25.0% 4.66% −0.73
ELAN Elanco Animal Health Inc. Sold out 0.00% −0.65
MRUS Merus NV Sold out 0.00% −0.59
PODD Insulet Corp. Sold out 0.00% −0.50
BPMC Blueprint Medicines Corp. Reduce -14.7% 3.16% −0.49
RLAY Relay Therapeutics Inc. Sold out 0.00% −0.49
SGRY Surgery Partners Inc. Sold out 0.00% −0.47
NVS Novartis AG-Sponsored ADR Reduce -33.3% 2.71% −0.47
CRBP Corbus Pharmaceuticals Holdi Sold out 0.00% −0.45
ISRG Intuitive Surgical Inc. Sold out 0.00% −0.44
ROIV Roivant Sciences Ltd. Sold out 0.00% −0.42
HOLX Hologic Inc. Sold out 0.00% −0.37
DYN Dyne Therapeutics Inc. Sold out 0.00% −0.35
EDIT Editas Medicine Inc. Sold out 0.00% −0.31
APGE Apogee Therapeutics Inc. Sold out 0.00% −0.31
SYRE Spyre Therapeutics Inc. Sold out 0.00% −0.23
MRK Merck & Co. Inc. Reduce -14.9% 2.67% −0.22
KURA Kura Oncology Inc. Sold out 0.00% −0.20
MREO Mereo Biopharma Group PL-ADR Reduce -43.7% 0.48% −0.15
TARS Tarsus Pharmaceuticals Inc. Reduce -36.4% 1.45% −0.14
RVNC Revance Therapeutics Inc. Sold out 0.00% −0.13
SRRK Scholar Rock Holding Corp. Reduce -31.3% 0.26% −0.07
TFX Teleflex Inc. Reduce -33.3% 0.87% −0.07
CRNX Crinetics Pharmaceuticals Inc. Reduce -25.0% 1.80% +0.02
QDEL Quidelortho Corp. Reduce -16.7% 0.67% +0.18
BSX Boston Scientific Corp. Reduce -15.4% 5.43% +0.44
EHC Encompass Health Corp. Reduce -8.3% 3.13% +0.57
LBPH Longboard Pharmaceuticals Inc. Reduce -4.5% 4.12% +1.16
INSM Insmed Inc. Reduce -6.5% 12.46% +2.13

Portfolio Buys Q2 2024 → Q3 2024

INSP Inspire Medical Systems Inc. New 3.98% +3.98
THC Tenet Healthcare Corp. Add +6.0% 10.37% +3.75
MDT Medtronic PLC New 3.18% +3.18
COO The Cooper Cos Inc. New 1.43% +1.43
FMS Fresenius Medical Care-ADR New 1.13% +1.13
BMY Bristol-Myers Squibb Co. New 1.07% +1.07
KROS Keros Therapeutics Inc. Add +135.3% 1.37% +0.98
DXCM Dexcom Inc. New 0.95% +0.95
BTSG Brightspring Health Services New 0.86% +0.86
DGX Quest Diagnostics Inc. Add +20.0% 2.19% +0.83
ALNY Alnylam Pharmaceuticals Inc. New 0.81% +0.81
APLT Applied Therapeutics Inc. New 0.80% +0.80
JSPR Jasper Therapeutics Inc. New 0.78% +0.78
TNDM Tandem Diabetes Care Inc. New 0.75% +0.75
BNTX Biontech SE-ADR New 0.70% +0.70
VRDN Viridian Therapeutics Inc. New 0.67% +0.67
EVH Evolent Health Inc. Class A New 0.67% +0.67
EXAS Exact Sciences Corp. New 0.64% +0.64
RVMD Revolution Medicines Inc. Add +7.7% 1.87% +0.61
IQV Iqvia Holdings Inc. New 0.56% +0.56
TWST Twist Bioscience Corp. New 0.53% +0.53
CPRX Catalyst Pharmaceuticals Inc. Add +45.5% 0.94% +0.51
MLYS Mineralys Therapeutics Inc. New 0.51% +0.51
RGNX Regenxbio Inc. Add +34.2% 1.57% +0.47
RVTY Revvity Inc. New 0.45% +0.45
MYGN Myriad Genetics Inc. New 0.40% +0.40
PLRX Pliant Therapeutics Inc. New 0.40% +0.40
TERN Terns Pharmaceuticals Inc. New 0.29% +0.29
BRKR Bruker Corp. Add +3.9% 1.10% +0.27
NTLA Intellia Therapeutics Inc. New 0.24% +0.24
QURE Uniqure NV New 0.23% +0.23
SANA Sana Biotechnology Inc. Add +50.0% 0.88% +0.23
GEHC GE Healthcare Technology New 0.22% +0.22
STAA Staar Surgical Co. New 0.22% +0.22
NRIX Nurix Therapeutics Inc. Add +33.3% 0.53% +0.22
TNGX Tango Therapeutics Inc. New 0.18% +0.18
RZLT Rezolute Inc. New 0.14% +0.14
FATE Fate Therapeutics Inc. Add +14.7% 0.40% +0.12
KYTX Kyverna Therapeutics Inc. New 0.12% +0.12
ETNB 89BIO Inc. Add +11.1% 0.44% +0.08
CABA Cabaletta Bio Inc. Add +5.9% 0.25% −0.07
TNYA Tenaya Therapeutics Inc. Add +2.1% 0.54% −0.18

Options Activity Q2 2024 → Q3 2024

IONS Ionis Pharmaceuticals Inc. call Sold out 500,000 $23.8Mbefore exit
EWTX Edgewise Therapeutics Inc. call New 500,000 $13.3M
TARS Tarsus Pharmaceuticals Inc. put Sold out 400,000 $10.9Mbefore exit
CLDX Celldex Therapeutics Inc. call New 300,000 $10.2M

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 89$2.4BRVMD, INSM, CYTK, CVS, EWTX
Q1 2026 86$1.9BINSM, RVMD, CYTK, REGN, VERA
Q4 2025 84$2.0BINSM, RVMD, VERA, CYTK, REGN
Q3 2025 72$1.4BINSM, CYTK, THC, MLYS, VERA
Q2 2025 70$1.1BINSM, BSX, THC, EHC, MLYS
Q1 2025 76$902.7MINSM, BSX, CYTK, THC, MLYS
Q4 2024 81$1.1BINSM, THC, BSX, VERA, CYTK
Q3 2024 63$849.4MINSM, THC, BSX, CYTK, LBPH
Q2 2024 69$1.0BINSM, THC, CYTK, BSX, ELV
Q1 2024 76$1.0BTHC, BSX, VKTX, INSM, CYTK