Integral Health Asset Management, LLC

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Integral Health Asset Management, LLC reported 86 stock positions worth $1.9 billion. Its top holding was Insmed (INSM) at 13.0% of the portfolio, followed by Revolution Medicines (RVMD, 7.7%) and Cytokinetics (CYTK, 5.6%). Compared with Q4 2025, it opened 26 new positions, sold out of 24, added to 31 and reduced 17. The biggest buy was Revolution Medicines (RVMD, shares +25%) and the biggest sale an exit from Medtronic (MDT).

Most Recent 13F
Q2 2026
Location
New York, NY
CIK
0001773206
Portfolio Value
$1.9B (Q1 2026)
SEC Filing
0001172661-26-002081 ↗ filed May 15, 2026

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.0B Q1 2024 Q2 2024: $1.0B Q2 2024 Q3 2024: $849.4M Q3 2024 Q4 2024: $1.1B Q4 2024 Q1 2025: $902.7M Q1 2025 Q2 2025: $1.1B Q2 2025 Q3 2025: $1.4B Q3 2025 Q4 2025: $2.0B Q4 2025 Q1 2026: $1.9B $1.9B Q1 2026 Q2 2026: $2.4B Q2 2026

Holdings 86 stocks · $1.9B

INSM Insmed Inc. 12.98% 1,500,000 $245.3M Add +20.0%
RVMD Revolution Medicines Inc. 7.72% 1,500,000 $145.9M Add +25.0%
CYTK Cytokinetics Inc. 5.58% 1,600,000 $105.5M Add +14.3%
REGN Regeneron Pharmaceuticals 3.48% 85,000 $65.7M Reduce -19.1%
VERA Vera Therapeutics Inc. 3.41% 1,600,000 $64.4M Reduce -11.1%
CAH Cardinal Health Inc. 3.02% 270,000 $57.1M Add +35.0%
ROIV Roivant Sciences Ltd. 2.93% 2,000,000 $55.4M Add +135.3%
BTSG Brightspring Health Services 2.82% 1,250,000 $53.3M Add +66.7%
RYTM Rhythm Pharmaceuticals Inc. 2.76% 600,000 $52.2M Add +26.3%
MRK Merck & Co. Inc. 2.71% 425,000 $51.1M Add +70.0%
EWTX Edgewise Therapeutics Inc. 2.67% 1,600,000 $50.4M Add +6.7%
AZN Astrazeneca PLC 2.61% 250,000 $49.3M Add +42.9%
ALHC Alignment Healthcare Inc. 2.40% 2,575,000 $45.4M Add +17.1%
NVS Novartis AG-Sponsored ADR 2.02% 250,000 $38.2M No change
BSX Boston Scientific Corp. 1.83% 550,000 $34.5M Add +144.4%
LFST Lifestance Health Group Inc. 1.45% 4,300,000 $27.4M Add +43.3%
ASND Ascendis Pharma A/S 1.39% 115,000 $26.3M Add +27.8%
SRRK Scholar Rock Holding Corp. 1.30% 500,000 $24.6M Add +66.7%
ELV Elevance Health Inc. 1.16% 75,000 $22.0M Add +25.0%
CNC Centene Corp. 1.13% 650,000 $21.3M No change
BBIO Bridgebio Pharma Inc. 1.08% 275,000 $20.4M New
MLYS Mineralys Therapeutics Inc. 1.08% 750,000 $20.3M No change
NBIX Neurocrine Biosciences Inc. 1.05% 150,000 $19.8M No change
GKOS Glaukos Corp. 1.00% 175,000 $18.8M Reduce -46.1%
ARWR Arrowhead Pharmaceuticals Inc. 1.00% 300,000 $18.8M Add +200.0%
VRTX Vertex Pharmaceuticals Inc. 0.95% 40,000 $17.9M New
ORIC Oric Pharmaceuticals Inc. 0.94% 1,400,000 $17.7M Add +16.7%
ALMS Alumis Inc. 0.93% 800,000 $17.6M New
FMS Fresenius Medical Care-ADR 0.93% 775,000 $17.5M Add +19.2%
ISRG Intuitive Surgical Inc. 0.85% 35,000 $16.1M Reduce -68.2%
QURE Uniqure NV 0.78% 900,000 $14.7M No change
TARS Tarsus Pharmaceuticals Inc. 0.74% 200,000 $14.0M No change
GILD Gilead Sciences Inc. 0.74% 100,000 $13.9M New
LLY Eli Lilly & Co. 0.73% 15,000 $13.8M Reduce -25.0%
EW Edwards Lifesciences Corp. 0.72% 170,000 $13.6M Reduce -47.7%
COGT Cogent Biosciences Inc. 0.71% 350,000 $13.5M New
ELAN Elanco Animal Health Inc. 0.70% 550,000 $13.2M Add +120.0%
MDGL Madrigal Pharmaceuticals Inc. 0.69% 25,000 $13.1M New
PRAX Praxis Precision Medicines I 0.68% 40,000 $12.9M No change
DNTH Dianthus Therapeutics Inc. 0.67% 150,000 $12.6M Reduce -45.5%
RGNX Regenxbio Inc. 0.67% 1,500,000 $12.6M Add +25.0%
DGX Quest Diagnostics Inc. 0.62% 60,000 $11.8M Reduce -20.0%
XENE Xenon Pharmaceuticals Inc. 0.62% 200,000 $11.6M New
ERAS Erasca Inc. 0.60% 700,000 $11.3M New
ANRO Alto Neuroscience Inc. 0.59% 500,000 $11.2M Add +33.3%
BIIB Biogen Inc. 0.58% 60,000 $11.0M Reduce -40.0%
DXCM Dexcom Inc. 0.58% 175,000 $11.0M Reduce -65.0%
SLNO Soleno Therapeutics Inc. 0.58% 325,000 $10.9M No change
IRON Disc Medicine Inc. 0.58% 170,000 $10.9M New
NRIX Nurix Therapeutics Inc. 0.57% 700,000 $10.8M Add +133.3%
CVS CVS Health Corp. 0.57% 150,000 $10.8M Reduce -70.0%
COO The Cooper Cos Inc. 0.57% 150,000 $10.7M Reduce -53.9%
TMO Thermo Fisher Scientific Inc. 0.52% 20,000 $9.8M New
LIVN Livanova PLC 0.50% 150,000 $9.5M New
LNTH Lantheus Holdings Inc. 0.50% 125,000 $9.5M Add +25.0%
TNGX Tango Therapeutics Inc. 0.50% 450,000 $9.4M Add +125.0%
IONS Ionis Pharmaceuticals Inc. 0.50% 125,000 $9.4M New
SANA Sana Biotechnology Inc. 0.49% 3,200,000 $9.2M Add +6.7%
CELC Celcuity Inc. 0.48% 80,000 $9.1M No change
TARA Protara Therapeutic Inc. 0.48% 1,750,000 $9.1M Reduce -22.2%
NVST Envista Holdings Corp. 0.47% 350,000 $8.9M Reduce -30.0%
BHVN Biohaven Ltd. 0.45% 1,000,000 $8.5M Reduce -33.3%
SNDX Syndax Pharmaceuticals Inc. 0.43% 350,000 $8.2M Add +75.0%
VKTX Viking Therapeutics Inc. 0.43% 250,000 $8.1M Add +150.0%
DFTX Definium Therapeutics Inc. 0.40% 400,000 $7.6M Add +14.3%
BEAM Beam Therapeutics Inc. 0.38% 300,000 $7.1M Reduce -45.5%
RZLT Rezolute Inc. 0.32% 2,000,000 $6.1M No change
CAPR Capricor Therapeutics Inc. 0.32% 200,000 $6.1M New
IQV Iqvia Holdings Inc. 0.32% 35,000 $6.0M New
AXSM Axsome Therapeutics Inc. 0.31% 35,000 $5.9M New
PTGX Protagonist Therapeutics Inc. 0.28% 50,000 $5.3M New
EVMN Evommune Inc. 0.27% 225,000 $5.2M Add +80.0%
ACHC Acadia Healthcare Co. Inc. 0.25% 200,000 $4.7M New
ZBH Zimmer Biomet Holdings Inc. 0.24% 50,000 $4.5M New
FBRX Forte Biosciences Inc. 0.21% 150,000 $3.9M New
LBRX LB Pharmaceuticals Inc. 0.20% 150,000 $3.7M Add +50.0%
SVRA Savara Inc. 0.17% 600,000 $3.3M New
RLMD Relmada Therapeutics Inc. 0.17% 450,000 $3.1M New
IMCR Immunocore Holdings PLC-ADR 0.16% 100,000 $3.0M New
MAZE Maze Therapeutics Inc. 0.16% 100,000 $3.0M No change
TENX Tenax Therapeutics Inc. 0.14% 167,000 $2.7M No change
IKT Inhibikase Therapeutics Inc. 0.12% 1,350,000 $2.3M Reduce -22.9%
OLMA Olema Pharmaceuticals Inc. 0.12% 150,000 $2.2M New
IVA Inventiva SA - ADR 0.12% 400,000 $2.2M New
SION Sionna Therapeutics Inc. 0.11% 50,000 $2.0M New
UNCY Unicycive Therapeutics Inc. 0.08% 225,000 $1.5M New

Options reported separately and not counted above: RVMD puts ($72.9M), CYTK calls ($65.9M), RVMD calls ($48.6M), MLYS calls ($13.5M).

Portfolio Sells Q4 2025 → Q1 2026

MDT Medtronic PLC Sold out 0.00% −3.29
ISRG Intuitive Surgical Inc. Reduce -68.2% 0.85% −2.30
TEVA Teva Pharmaceutical-SP ADR Sold out 0.00% −1.58
PEN Penumbra Inc. Sold out 0.00% −1.58
TFX Teleflex Inc. Sold out 0.00% −1.55
CVS CVS Health Corp. Reduce -70.0% 0.57% −1.44
VERA Vera Therapeutics Inc. Reduce -11.1% 3.41% −1.21
ALNY Alnylam Pharmaceuticals Inc. Sold out 0.00% −1.21
IRTC Irhythm Holdings Inc. Sold out 0.00% −1.17
DXCM Dexcom Inc. Reduce -65.0% 0.58% −1.10
UPB Upstream Bio Inc. Sold out 0.00% −1.03
THC Tenet Healthcare Corp. Sold out 0.00% −1.01
DOCS Doximity Inc. Class A Sold out 0.00% −0.90
TERN Terns Pharmaceuticals Inc. Sold out 0.00% −0.87
GKOS Glaukos Corp. Reduce -46.1% 1.00% −0.86
UNH Unitedhealth Group Inc. Sold out 0.00% −0.84
COO The Cooper Cos Inc. Reduce -53.9% 0.57% −0.78
RDNT Radnet Inc. Sold out 0.00% −0.72
EW Edwards Lifesciences Corp. Reduce -47.7% 0.72% −0.68
ACLX Arcellx Inc. Sold out 0.00% −0.66
REGN Regeneron Pharmaceuticals Reduce -19.1% 3.48% −0.63
EHC Encompass Health Corp. Sold out 0.00% −0.54
CRL Charles River Laboratories Sold out 0.00% −0.45
BHVN Biohaven Ltd. Reduce -33.3% 0.45% −0.41
BEAM Beam Therapeutics Inc. Reduce -45.5% 0.38% −0.39
LLY Eli Lilly & Co. Reduce -25.0% 0.73% −0.36
INSP Inspire Medical Systems Inc. Sold out 0.00% −0.35
BIIB Biogen Inc. Reduce -40.0% 0.58% −0.31
BRKR Bruker Corp. Sold out 0.00% −0.30
APLS Apellis Pharmaceuticals Inc. Sold out 0.00% −0.25
EYPT Eyepoint Inc. Sold out 0.00% −0.19
GPCR Structure Therapeutics Inc. Sold out 0.00% −0.18
SGHT Sight Sciences Inc. Sold out 0.00% −0.17
GOSS Gossamer Bio Inc. Sold out 0.00% −0.16
OSCR Oscar Health Inc. Class A Sold out 0.00% −0.15
TARA Protara Therapeutic Inc. Reduce -22.2% 0.48% −0.13
NVST Envista Holdings Corp. Reduce -30.0% 0.47% −0.08
BCRX Biocryst Pharmaceuticals Inc. Sold out 0.00% −0.08
IKT Inhibikase Therapeutics Inc. Reduce -22.9% 0.12% −0.06
DGX Quest Diagnostics Inc. Reduce -20.0% 0.62% −0.04
DNTH Dianthus Therapeutics Inc. Reduce -45.5% 0.67% +0.09

Portfolio Buys Q4 2025 → Q1 2026

RVMD Revolution Medicines Inc. Add +25.0% 7.72% +2.87
ROIV Roivant Sciences Ltd. Add +135.3% 2.93% +2.00
INSM Insmed Inc. Add +20.0% 12.98% +1.95
BTSG Brightspring Health Services Add +66.7% 2.82% +1.39
MRK Merck & Co. Inc. Add +70.0% 2.71% +1.37
BBIO Bridgebio Pharma Inc. New 1.08% +1.08
CYTK Cytokinetics Inc. Add +14.3% 5.58% +1.07
AZN Astrazeneca PLC Add +42.9% 2.61% +0.98
VRTX Vertex Pharmaceuticals Inc. New 0.95% +0.95
CAH Cardinal Health Inc. Add +35.0% 3.02% +0.94
ALMS Alumis Inc. New 0.93% +0.93
EWTX Edgewise Therapeutics Inc. Add +6.7% 2.67% +0.78
BSX Boston Scientific Corp. Add +144.4% 1.83% +0.74
GILD Gilead Sciences Inc. New 0.74% +0.74
COGT Cogent Biosciences Inc. New 0.71% +0.71
MDGL Madrigal Pharmaceuticals Inc. New 0.69% +0.69
ARWR Arrowhead Pharmaceuticals Inc. Add +200.0% 1.00% +0.66
SRRK Scholar Rock Holding Corp. Add +66.7% 1.30% +0.63
XENE Xenon Pharmaceuticals Inc. New 0.62% +0.62
ERAS Erasca Inc. New 0.60% +0.60
IRON Disc Medicine Inc. New 0.58% +0.58
TMO Thermo Fisher Scientific Inc. New 0.52% +0.52
LIVN Livanova PLC New 0.50% +0.50
IONS Ionis Pharmaceuticals Inc. New 0.50% +0.50
ORIC Oric Pharmaceuticals Inc. Add +16.7% 0.94% +0.44
ASND Ascendis Pharma A/S Add +27.8% 1.39% +0.42
ELAN Elanco Animal Health Inc. Add +120.0% 0.70% +0.41
TNGX Tango Therapeutics Inc. Add +125.0% 0.50% +0.41
LFST Lifestance Health Group Inc. Add +43.3% 1.45% +0.38
CAPR Capricor Therapeutics Inc. New 0.32% +0.32
IQV Iqvia Holdings Inc. New 0.32% +0.32
AXSM Axsome Therapeutics Inc. New 0.31% +0.31
NRIX Nurix Therapeutics Inc. Add +133.3% 0.57% +0.29
PTGX Protagonist Therapeutics Inc. New 0.28% +0.28
ANRO Alto Neuroscience Inc. Add +33.3% 0.59% +0.26
VKTX Viking Therapeutics Inc. Add +150.0% 0.43% +0.25
ACHC Acadia Healthcare Co. Inc. New 0.25% +0.25
ZBH Zimmer Biomet Holdings Inc. New 0.24% +0.24
SNDX Syndax Pharmaceuticals Inc. Add +75.0% 0.43% +0.22
FBRX Forte Biosciences Inc. New 0.21% +0.21
ALHC Alignment Healthcare Inc. Add +17.1% 2.40% +0.20
RYTM Rhythm Pharmaceuticals Inc. Add +26.3% 2.76% +0.18
SVRA Savara Inc. New 0.17% +0.17
RLMD Relmada Therapeutics Inc. New 0.17% +0.17
EVMN Evommune Inc. Add +80.0% 0.27% +0.17
LNTH Lantheus Holdings Inc. Add +25.0% 0.50% +0.16
DFTX Definium Therapeutics Inc. Add +14.3% 0.40% +0.16
IMCR Immunocore Holdings PLC-ADR New 0.16% +0.16
FMS Fresenius Medical Care-ADR Add +19.2% 0.93% +0.14
OLMA Olema Pharmaceuticals Inc. New 0.12% +0.12

Options Activity Q4 2025 → Q1 2026

RVMD Revolution Medicines Inc. put New 750,000 $72.9M
CYTK Cytokinetics Inc. call Add +100.0% 1,000,000 $65.9M
RVMD Revolution Medicines Inc. call New 500,000 $48.6M
MLYS Mineralys Therapeutics Inc. call Add +100.0% 500,000 $13.5M

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 89$2.4BRVMD, INSM, CYTK, CVS, EWTX
Q1 2026 86$1.9BINSM, RVMD, CYTK, REGN, VERA
Q4 2025 84$2.0BINSM, RVMD, VERA, CYTK, REGN
Q3 2025 72$1.4BINSM, CYTK, THC, MLYS, VERA
Q2 2025 70$1.1BINSM, BSX, THC, EHC, MLYS
Q1 2025 76$902.7MINSM, BSX, CYTK, THC, MLYS
Q4 2024 81$1.1BINSM, THC, BSX, VERA, CYTK
Q3 2024 63$849.4MINSM, THC, BSX, CYTK, LBPH
Q2 2024 69$1.0BINSM, THC, CYTK, BSX, ELV
Q1 2024 76$1.0BTHC, BSX, VKTX, INSM, CYTK