Orchestra Biomed HoldingsOBIO

13F holders, Q2 2026 (June 30)
77holders +12
25new positions
13sold out
2famous investors
$4.31avg. 13F price*

At the end of Q2 2026, 77 institutions reported holding Orchestra Biomed Holdings Inc. (OBIO) in their 13F filings, up 12 from Q1 2026. 25 opened new positions and 13 sold out. The largest holders were RTW Investments, LP ($41.2M), Perceptive Advisors LLC ($21.7M) and BlackRock, Inc. ($10.8M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Orchestra Biomed Holdings Inc.
CUSIP
68572M106
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 43Q1 2024Q2 2024: 47Q2 2024Q3 2024: 48Q3 2024Q4 2024: 54Q4 2024Q1 2025: 56Q1 2025Q2 2025: 59Q2 2025Q3 2025: 52Q3 2025Q4 2025: 63Q4 2025Q1 2026: 65Q1 2026Q2 2026: 77Q2 2026

Total Exit/New Position Q1 2026 → Q2 2026

InstitutionsTotal Value
New Positions25$7.2M
Exits13$6.3M

All 13F filers, Q1 2026 → Q2 2026: 6,885,585 shares bought and 2,287,151 shares sold, net +4,598,434 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 77 holders

RTW Investments, LP 0.35% Add +15.1% 9,556,063 $41.2M
Perceptive Advisors LLC 0.34% No change 5,037,906 $21.7M
BlackRock, Inc. 0.00% Add +294.9% 2,510,387 $10.8M
Vanguard Capital Management LLC 0.00% Reduce -8.2% 2,022,916 $8.7M
Geode Capital Management, LLC 0.00% Add +107.6% 1,007,908 $4.4M
Alyeska Investment Group, L.P. 0.01% No change 1,000,000 $4.3M
Propel Bio Management, LLC 2.02% No change 896,701 $3.9M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 642,154 $2.8M
State Street Corp. 0.00% Add +204.6% 516,050 $2.2M
Rice Hall James & Associates, LLC 0.09% Add +2131.5% 424,000 $1.8M
Charles Schwab Investment Management Inc. 0.00% Add +31.7% 349,544 $1.5M
Northern Trust Corp. 0.00% Add +190.6% 343,640 $1.5M
UBS Group AG 0.00% Add +547.5% 325,773 $1.4M
Vanguard Fiduciary Trust Co. 0.00% Add +24.3% 292,253 $1.3M
Vanguard Portfolio Management LLC 0.00% New 274,973 $1.2M
Knott David M Jr 0.58% No change 253,651 $1.1M
Flat Footed LLC 0.19% New 251,372 $1.1M
Simplify Asset Management Inc. 0.01% No change 219,387 $947K
Goldman Sachs Group Inc. 0.00% Add +15.7% 179,606 $775K
DAFNA Capital Management LLC 0.10% No change 126,841 $547K
Renaissance Technologies 0.00% Add +26.9% 90,000 $388K
IFP Advisors, Inc 0.01% Reduce -9.4% 89,608 $387K
Daytona Street Capital LLC 0.28% Add +83.3% 96,398 $379K
Bank of New York Mellon Corp 0.00% New 86,103 $372K
Bridgeway Capital Management, LLC 0.01% Add +14.2% 80,600 $348K
Susquehanna International Group, LLP 0.00% Reduce -32.5% 65,804 $284K
Citadel Advisors 0.00% Reduce -29.0% 56,191 $242K
Nuveen, LLC 0.00% New 52,118 $225K
Holos Integrated Wealth LLC 0.10% No change 51,595 $204K
NewEdge Advisors, LLC 0.00% No change 44,083 $190K
Y-Intercept (Hong Kong) Ltd 0.00% New 43,486 $188K
Deutsche Bank AG 0.00% New 39,672 $171K
XTX Topco Ltd 0.00% New 38,814 $167K
Wells Fargo & Company 0.00% New 36,356 $157K
HighTower Advisors, LLC 0.00% Add +93.6% 35,375 $153K
Affinity Asset Advisors, LLC 0.01% Reduce -91.7% 33,400 $144K
T. Rowe Price Associates Inc. 0.00% New 32,689 $142K
Rhumbline Advisers 0.00% New 31,940 $138K
Morgan Stanley 0.00% Reduce -18.2% 29,160 $126K
Algert Global LLC 0.00% Add +94.4% 28,486 $123K
Meramec Financial Planners, LLC 0.04% No change 30,000 $115K
Axq Capital, LP 0.01% New 25,448 $110K
Invesco Ltd. 0.00% New 24,689 $107K
MetLife Investment Management, LLC 0.00% New 23,994 $104K
Bank of America Corp. 0.00% Reduce -54.9% 23,822 $103K
JPMorgan Chase & Co. 0.00% Add +390.4% 20,880 $99K
Two Sigma Investments, LP 0.00% Reduce -62.5% 22,563 $97K
Canada Pension Plan Investment Board 0.00% Add +86.7% 21,100 $91K
New York State Common Retirement Fund 0.00% New 20,400 $88K
Citigroup Inc. 0.00% Reduce -21.0% 20,165 $87K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% New 18,352 $79K
Jane Street Group, LLC 0.00% Reduce -72.4% 15,360 $66K
Vanguard Global Advisers, LLC 0.00% No change 13,948 $60K
Barclays PLC 0.00% Reduce -77.2% 13,518 $58K
ABLE Financial Group, LLC 0.01% No change 13,402 $58K
Sargent Investment Group, LLC 0.01% New 13,120 $57K
Frec Markets, Inc. 0.01% No change 13,048 $56K
Police & Firemen's Retirement System of New Jersey 0.00% New 11,755 $51K
Garden State Investment Advisory Services LLC 0.01% No change 10,562 $46K
China Universal Asset Management Co., Ltd. 0.00% Reduce -4.9% 9,530 $41K
BNP Paribas Financial Markets 0.00% Add +464.1% 8,214 $35K
Legal & General Group Plc 0.00% New 3,924 $17K
Ameritas Investment Partners, Inc. 0.00% New 3,617 $16K
Tower Research Capital LLC (TRC) 0.00% Add +558.3% 3,601 $16K
Russell Investments Group, Ltd. 0.00% New 3,187 $14K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -9.1% 2,678 $12K
Simplex Trading, LLC 0.00% Add +7.7% 2,564 $11K
Royal Bank of Canada 0.00% Add +99.2% 1,864 $8K
AdvisorNet Financial, Inc 0.00% No change 1,696 $7K
GF Fund Management Co. LTD. 0.00% Reduce -6.9% 1,173 $5K
Jones Financial Companies LLLP 0.00% Add +128.9% 888 $4K
California State Teachers Retirement System 0.00% New 549 $2K
FMR LLC 0.00% Reduce -98.5% 265 $1K
Sterling Capital Management LLC 0.00% New 140 $604
Optiver Holding B.V. 0.00% New 40 $173
Caitong International Asset Management Co., Ltd 0.00% New 15 $65
SBI Securities Co., Ltd. 0.00% No change 6 $26

"% of holder's portfolio" is OBIO's weight in each manager's 13F, not the share of Orchestra Biomed Holdings Inc. the manager owns.