Nantahala Capital Management, LLC

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 14, 2025), Nantahala Capital Management, LLC reported 118 stock positions worth $1.4 billion. Its top holding was Soleno Therapeutics (SLNO) at 12.4% of the portfolio, followed by Establishment Labs (ESTA, 5.3%) and Hilton Grand Vacations (HGV, 4.7%). Compared with Q3 2024, it opened 16 new positions, sold out of 17, added to 43 and reduced 25. The biggest buy was Hilton Grand Vacations (HGV, shares +132%) and the biggest sale Establishment Labs (ESTA, shares −30%).

Most Recent 13F
Q2 2026
Location
NEW CANAAN, CT
CIK
0001472322
Portfolio Value
$1.4B (Q4 2024)
SEC Filing
0001104659-25-014223 ↗ filed Feb 14, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B Q1 2024: $1.0B Q1 2024 Q2 2024: $994.2M Q2 2024 Q3 2024: $1.2B Q3 2024 Q4 2024: $1.4B $1.4B Q4 2024 Q1 2025: $1.2B Q1 2025 Q2 2025: $1.4B Q2 2025 Q3 2025: $1.6B Q3 2025 Q4 2025: $1.7B Q4 2025 Q1 2026: $1.6B Q1 2026 Q2 2026: $1.6B Q2 2026

Holdings 118 stocks · $1.4B

SLNO Soleno Therapeutics Inc. 12.35% 3,928,966 $176.6M Add +20.1%
ESTA Establishment Labs Holdings 5.33% 1,654,470 $76.2M Reduce -29.9%
HGV Hilton Grand Vacations Inc. 4.72% 1,730,995 $67.4M Add +131.8%
PTON Peloton Interactive Inc. Class A 4.40% 7,224,903 $62.9M Reduce -30.2%
TBBK The Bancorp Inc. 3.59% 974,455 $51.3M Add +65.7%
QURE Uniqure NV 3.03% 2,453,364 $43.3M Reduce -11.8%
BVS Bioventus Inc. Class A 2.96% 4,026,809 $42.3M Reduce -7.5%
EOLS Evolus Inc. 2.42% 3,130,149 $34.6M Add +10.8%
IMAX Imax Corp. 2.06% 1,150,351 $29.4M Reduce -10.0%
AMRX Amneal Pharmaceuticals Inc. 2.03% 3,665,529 $29.0M Add +37.3%
CRMT America's Car-Mart Inc. 1.95% 544,686 $27.9M No change
SVRA Savara Inc. 1.62% 7,525,259 $23.1M Add +45.3%
TITN Titan Machinery Inc. 1.61% 1,625,276 $23.0M No change
FULC Fulcrum Therapeutics Inc. 1.57% 4,779,708 $22.5M Add +0.0%
IWM iShares Russell 2000 ETF 1.51% 97,637 $21.6M Add +4088.6%
GOGO Gogo Inc. 1.46% 2,574,642 $20.8M Add +441.5%
SVC Service Pptys TR 1.44% 8,091,900 $20.6M New
EB Eventbrite Inc. Class A 1.39% 5,930,947 $19.9M Add +76.5%
ABEO Abeona Therapeutics Inc. 1.38% 3,529,214 $19.7M Add +2.8%
ZVRA Zevra Therapeutics Inc. 1.37% 2,340,333 $19.5M Reduce -20.0%
VSTM Verastem Inc. 1.36% 3,752,583 $19.4M Add +0.5%
FOXF Fox Factory Holding Corp. 1.35% 635,994 $19.3M New
EHTH Ehealth Inc. 1.32% 2,009,500 $18.9M Add +5.1%
RDNW Ridenow Group Inc. filed as RUMBLEON INC 1.24% 3,274,138 $17.8M Add +6.8%
PAYO Payoneer Global Inc. 1.08% 1,538,600 $15.4M Reduce -27.3%
RDVT Red Violet Inc. 1.07% 422,466 $15.3M Reduce -6.6%
ETON Eton Pharmaceuticals Inc. 1.04% 1,118,483 $14.9M Add +12.0%
BKSY Blacksky Technology Inc. 1.04% 1,377,060 $14.9M Reduce -43.8%
URGN Urogen Pharma Ltd. 1.02% 1,371,638 $14.6M New
KROS Keros Therapeutics Inc. 1.01% 915,048 $14.5M Add +139.8%
RSVR Reservoir Media Inc. 0.99% 1,560,797 $14.1M No change
CASH Pathward Financial Inc. 0.98% 191,343 $14.1M Reduce -27.6%
RZLT Rezolute Inc. 0.98% 2,857,982 $14.0M Add +10.9%
CDXS Codexis Inc. 0.95% 2,841,660 $13.6M Reduce -4.3%
TELA Tela Bio Inc. 0.78% 3,679,726 $11.1M Add +92.1%
TRML Tourmaline Bio Inc. 0.76% 536,944 $10.9M Reduce -23.4%
ELUT Elutia Inc. 0.75% 2,864,947 $10.7M No change
BNTC Benitec Biopharma Inc. 0.74% 838,095 $10.6M No change
ABVX Abivax SA-ADR 0.74% 1,436,047 $10.5M Add +45.7%
AURA Aura Biosciences Inc. 0.73% 1,270,035 $10.4M No change
UPB Upstream Bio Inc. 0.69% 600,000 $9.9M New
IRON Disc Medicine Inc. 0.67% 150,000 $9.5M No change
RMR RMR Group Inc./the - A 0.65% 450,792 $9.3M Add +32.8%
AVR Anteris Technologies Global 0.65% 1,666,666 $9.3M New
TNGX Tango Therapeutics Inc. 0.61% 2,804,410 $8.7M New
CNTA Centessa Pharmaceuticals Ltd. 0.60% 512,647 $8.6M No change
UNICYCIVE THERAPEUTICS INC 0.58% 10,391,994 $8.3M Add +268.5%
MLYS Mineralys Therapeutics Inc. 0.54% 632,506 $7.8M No change
ILPT Industrial Logistics Propert 0.54% 2,107,893 $7.7M Add +86.3%
VMD Viemed Healthcare Inc. 0.52% 935,122 $7.5M Reduce -17.6%
SNDX Syndax Pharmaceuticals Inc. 0.52% 560,532 $7.4M Add +23.7%
NKTR Nektar Therapeutics 0.51% 7,810,000 $7.3M Add +90.0%
SLN Silence Therapeutics PLC-ADR 0.51% 1,049,676 $7.2M Add +424.8%
IKT Inhibikase Therapeutics Inc. 0.50% 2,190,000 $7.1M New
ASSERTIO HOLDINGS INC 0.50% 8,148,336 $7.1M Reduce -8.9%
COGT Cogent Biosciences Inc. 0.47% 852,855 $6.7M Add +7.8%
OPTINOSE INC 0.46% 986,031 $6.6M Add +3.0%
NPCE Neuropace Inc. 0.44% 562,073 $6.3M Reduce -7.5%
STKS One Group Hospitality Inc. filed as THE ONE GROUP HOSPITALITY IN 0.42% 2,087,394 $6.1M Add +23.9%
ATXS Astria Therapeutics Inc. 0.42% 675,000 $6.0M No change
GPCR Structure Therapeutics Inc. 0.42% 221,000 $6.0M Add +29.2%
VTGN Vistagen Therapeutics Inc. 0.41% 1,981,980 $5.8M Add +30.6%
FOSL Fossil Group Inc. 0.39% 3,326,677 $5.6M Add +74.6%
ALTG Alta Equipment Group Inc. 0.39% 845,115 $5.5M No change
AMLX Amylyx Pharmaceuticals Inc. 0.38% 1,452,153 $5.5M Add +3.4%
THRD Third Harmonic Bio Inc. 0.36% 501,000 $5.2M New
ANEB Anebulo Pharmaceuticals Inc. 0.36% 3,036,325 $5.1M Add +494.1%
XTNT Xtant Medical Holdings Inc. 0.35% 11,394,000 $5.0M No change
APYX Apyx Medical Corp. 0.35% 3,169,800 $5.0M New
LXRX Lexicon Pharmaceuticals Inc. 0.34% 6,604,150 $4.9M Add +186.6%
THTX Theratechnologies Inc. 0.34% 2,682,228 $4.9M No change
NNBR NN Inc. 0.33% 1,458,416 $4.8M No change
ELDN Eledon Pharmaceuticals Inc. 0.33% 1,147,946 $4.7M Add +91.3%
EYPT Eyepoint Inc. 0.31% 600,000 $4.5M New
NSPR Inspiremd Inc. 0.31% 1,674,565 $4.4M Reduce -24.2%
DHX Dhi Group Inc. 0.29% 2,376,606 $4.2M No change
IMTX Immatics NV 0.29% 578,856 $4.1M Reduce -7.5%
GAIA Gaia Inc. 0.29% 915,029 $4.1M No change
ZYXIQ Zynex Inc. 0.27% 490,000 $3.9M No change
RDI Reading International Inc. Class A 0.26% 2,864,046 $3.8M Reduce -11.5%
CMPS Compass Pathways PLC 0.26% 1,000,000 $3.8M Add +400.0%
OCUL Ocular Therapeutix Inc. 0.26% 437,728 $3.7M Reduce -37.5%
SCPH Scpharmaceuticals Inc. 0.25% 1,000,000 $3.5M Add +33.3%
MIST Milestone Pharmaceuticals Inc. 0.24% 1,445,264 $3.4M Reduce -17.4%
SRL Scully Royalty Ltd. 0.24% 368,596 $3.4M Add +54.1%
CZR Caesars Entertainment Inc. 0.23% 100,000 $3.3M New
PVLA Palvella Therapeutics Inc. 0.21% 250,062 $3.0M New
SRZN Surrozen Inc. 0.20% 196,023 $2.8M Add +4.7%
KOD Kodiak Sciences Inc. 0.19% 266,613 $2.7M Add +287.2%
NDLS Noodles & Co. 0.18% 4,508,329 $2.6M No change
ACHV Achieve Life Sciences Inc. 0.16% 654,000 $2.3M No change
CNTX Context Therapeutics Inc. 0.14% 1,935,484 $2.0M No change
RAPT THERAPEUTICS INC 0.14% 1,243,513 $2.0M New
DRIO Dariohealth Corp. 0.13% 2,444,677 $1.9M Reduce -2.3%
AYTU Aytu Biopharma Inc. 0.13% 1,086,812 $1.8M No change
NVNO Envveno Medical Corporation 0.13% 596,917 $1.8M No change
BCOV Brightcove 0.11% 358,052 $1.6M Reduce -78.5%
PERF Perfect Corp. 0.10% 500,000 $1.4M Add +19.3%
ALTISOURCE PORTFOLIO SOLNS S 0.10% 2,128,284 $1.4M Add +95.1%
MAX Mediaalpha Inc. Class A 0.10% 123,564 $1.4M No change
TYRA Tyra Biosciences Inc. 0.10% 100,000 $1.4M New
SGRP Spar Group Inc. 0.09% 662,028 $1.3M No change
AEROVATE THERAPEUTICS INC 0.09% 482,928 $1.3M New
BIOMX INC 0.09% 1,730,600 $1.2M No change
SSKN Strata Skin Sciences Inc. 0.08% 403,917 $1.2M No change
TLPH Talphera Inc. 0.07% 1,992,519 $1.0M No change
KPRX Kiora Pharmaceuticals Inc. 0.05% 211,110 $697K No change
APRE Aprea Therapeutics Inc. 0.05% 205,760 $677K No change
EVOK Evoke Pharma Inc. 0.05% 148,194 $655K Add +163.5%
LAZYDAYS HLDGS INC 0.04% 551,135 $526K No change
OKUR Onkure Therapeutics Inc. Class A 0.03% 54,777 $471K New
EWTX Edgewise Therapeutics Inc. 0.03% 13,371 $357K No change
PLCE The Children's Place Inc. 0.02% 29,314 $307K No change
LADR Ladder Capital Corp.-REIT 0.02% 25,631 $287K No change
XGN Exagen Inc. 0.02% 62,116 $255K No change
FBIO Fortress Biotech Inc. 0.02% 125,520 $254K Reduce -18.0%
LUCD Lucid Diagnostics Inc. 0.01% 94,541 $77K Reduce -25.2%
TACT Transact Technologies Inc. 0.00% 15,046 $62K Reduce -25.2%

Options reported separately and not counted above: IWM puts ($530.3M), LLY puts ($123.5M), XBI puts ($112.6M), PTON calls ($44.3M), SYK puts ($36.0M), RDNW calls ($9.2M), KRYS puts ($7.8M), CZR calls ($6.7M), IMAX calls ($6.4M), HLF calls ($5.4M), GPCR calls ($4.1M), KROS calls ($4.0M), and 3 more.

Other holdings (4): bonds, preferreds, convertibles and warrants · $120K (not counted above)
SecurityClassShares / PrincipalValueChange
IMTXW Immatics NV -CW *W EXP 07/01/202 248,506$62KNo change
GFAIW Guardforce AI Co. Ltd. -CW26 *W EXP 10/01/202 154,205$54KNo change
TCBWF TC Biopharm Holdings Ltd. *W EXP 02/10/202 235,294$2KNo change
PERFF Perfect Corp. *W EXP 10/28/202 16,075$1KNo change

Total filed on the 13F, all lines: $1.4B.

Portfolio Sells Q3 2024 → Q4 2024

ESTA Establishment Labs Holdings Reduce -29.9% 5.33% −3.26
BVS Bioventus Inc. Class A Reduce -7.5% 2.96% −1.42
PWSC Powerschool Holdings Inc. Class A Sold out 0.00% −1.12
TRML Tourmaline Bio Inc. Reduce -23.4% 0.76% −0.76
EGRX Eagle Pharmaceuticals Inc. Sold out 0.00% −0.74
VNDA Vanda Pharmaceuticals Inc. Sold out 0.00% −0.63
CLRB Cellectar Biosciences Inc. Sold out 0.00% −0.49
CASH Pathward Financial Inc. Reduce -27.6% 0.98% −0.48
LXFR Luxfer Holdings PLC Sold out 0.00% −0.45
ASSERTIO HOLDINGS INC Reduce -8.9% 0.50% −0.39
ZVRA Zevra Therapeutics Inc. Reduce -20.0% 1.37% −0.34
IMTX Immatics NV Reduce -7.5% 0.29% −0.31
PAYO Payoneer Global Inc. Reduce -27.3% 1.08% −0.26
OCUL Ocular Therapeutix Inc. Reduce -37.5% 0.26% −0.25
BCOV Brightcove Reduce -78.5% 0.11% −0.19
NSPR Inspiremd Inc. Reduce -24.2% 0.31% −0.19
XBI SS SPDR S&P Biotech ETF Sold out 0.00% −0.18
RDI Reading International Inc. Class A Reduce -11.5% 0.26% −0.18
VMD Viemed Healthcare Inc. Reduce -17.6% 0.52% −0.18
NGNE Neurogene Inc. Sold out 0.00% −0.15
IMAX Imax Corp. Reduce -10.0% 2.06% −0.15
RNTX Rein Therapeutics Inc. Sold out 0.00% −0.14
TIL Instil Bio Inc. Sold out 0.00% −0.11
DRIO Dariohealth Corp. Reduce -2.3% 0.13% −0.10
RENEO PHARMACEUTICALS INC Sold out 0.00% −0.08
NEUROONE MED TECHNOLOGIES CO Sold out 0.00% −0.07
RILY BRC Group Holdings Inc. Sold out 0.00% −0.06
GOSS Gossamer Bio Inc. Sold out 0.00% −0.06
BMTX BM Technologies Inc. Sold out 0.00% −0.02
RDVT Red Violet Inc. Reduce -6.6% 1.07% −0.01
TACT Transact Technologies Inc. Reduce -25.2% 0.00% −0.00
LUCD Lucid Diagnostics Inc. Reduce -25.2% 0.01% −0.00
APTOSE BIOSCIENCES INC Sold out 0.00% −0.00
RENALYTIX AI PLC-ADR Sold out 0.00% −0.00
KINTARA THERAPEUTICS INC Sold out 0.00% −0.00
FBIO Fortress Biotech Inc. Reduce -18.0% 0.02% −0.00
MIST Milestone Pharmaceuticals Inc. Reduce -17.4% 0.24% +0.01
BKSY Blacksky Technology Inc. Reduce -43.8% 1.04% +0.06
NPCE Neuropace Inc. Reduce -7.5% 0.44% +0.08
CDXS Codexis Inc. Reduce -4.3% 0.95% +0.18
PTON Peloton Interactive Inc. Class A Reduce -30.2% 4.40% +0.32
QURE Uniqure NV Reduce -11.8% 3.03% +1.88

Portfolio Buys Q3 2024 → Q4 2024

HGV Hilton Grand Vacations Inc. Add +131.8% 4.72% +2.43
IWM iShares Russell 2000 ETF Add +4088.6% 1.51% +1.47
SVC Service Pptys TR New 1.44% +1.44
FOXF Fox Factory Holding Corp. New 1.35% +1.35
GOGO Gogo Inc. Add +441.5% 1.46% +1.17
URGN Urogen Pharma Ltd. New 1.02% +1.02
TBBK The Bancorp Inc. Add +65.7% 3.59% +0.94
UPB Upstream Bio Inc. New 0.69% +0.69
EHTH Ehealth Inc. Add +5.1% 1.32% +0.66
AVR Anteris Technologies Global New 0.65% +0.65
EB Eventbrite Inc. Class A Add +76.5% 1.39% +0.62
TNGX Tango Therapeutics Inc. New 0.61% +0.61
ETON Eton Pharmaceuticals Inc. Add +12.0% 1.04% +0.54
IKT Inhibikase Therapeutics Inc. New 0.50% +0.50
UNICYCIVE THERAPEUTICS INC Add +268.5% 0.58% +0.48
VSTM Verastem Inc. Add +0.5% 1.36% +0.42
TELA Tela Bio Inc. Add +92.1% 0.78% +0.37
THRD Third Harmonic Bio Inc. New 0.36% +0.36
APYX Apyx Medical Corp. New 0.35% +0.35
EYPT Eyepoint Inc. New 0.31% +0.31
ANEB Anebulo Pharmaceuticals Inc. Add +494.1% 0.36% +0.27
CZR Caesars Entertainment Inc. New 0.23% +0.23
PVLA Palvella Therapeutics Inc. New 0.21% +0.21
ELDN Eledon Pharmaceuticals Inc. Add +91.3% 0.33% +0.21
FOSL Fossil Group Inc. Add +74.6% 0.39% +0.20
SLN Silence Therapeutics PLC-ADR Add +424.8% 0.51% +0.20
KOD Kodiak Sciences Inc. Add +287.2% 0.19% +0.17
AMRX Amneal Pharmaceuticals Inc. Add +37.3% 2.03% +0.16
CMPS Compass Pathways PLC Add +400.0% 0.26% +0.16
RAPT THERAPEUTICS INC New 0.14% +0.14
FULC Fulcrum Therapeutics Inc. Add +0.0% 1.57% +0.14
TYRA Tyra Biosciences Inc. New 0.10% +0.10
AEROVATE THERAPEUTICS INC New 0.09% +0.09
ILPT Industrial Logistics Propert Add +86.3% 0.54% +0.08
SRL Scully Royalty Ltd. Add +54.1% 0.24% +0.08
NKTR Nektar Therapeutics Add +90.0% 0.51% +0.06
LXRX Lexicon Pharmaceuticals Inc. Add +186.6% 0.34% +0.04
OKUR Onkure Therapeutics Inc. Class A New 0.03% +0.03
PERF Perfect Corp. Add +19.3% 0.10% +0.03
VTGN Vistagen Therapeutics Inc. Add +30.6% 0.41% +0.02
EVOK Evoke Pharma Inc. Add +163.5% 0.05% +0.02
SRZN Surrozen Inc. Add +4.7% 0.20% +0.01
RDNW Ridenow Group Inc. Add +6.8% 1.24% +0.01
AMLX Amylyx Pharmaceuticals Inc. Add +3.4% 0.38% +0.00
ALTISOURCE PORTFOLIO SOLNS S Add +95.1% 0.10% −0.01
SCPH Scpharmaceuticals Inc. Add +33.3% 0.25% −0.04
RZLT Rezolute Inc. Add +10.9% 0.98% −0.07
RMR RMR Group Inc./the - A Add +32.8% 0.65% −0.07
STKS One Group Hospitality Inc. Add +23.9% 0.42% −0.10
GPCR Structure Therapeutics Inc. Add +29.2% 0.42% −0.21

Options Activity Q3 2024 → Q4 2024

IWM iShares Russell 2000 ETF put Add +29.7% 2,400,000 $530.3M
LLY Eli Lilly & Co. put Add +77.8% 160,000 $123.5M
XBI SS SPDR S&P Biotech ETF put Add +56.3% 1,250,000 $112.6M
LOPE Grand Canyon Education Inc. put Sold out 400,000 $56.7Mbefore exit
PTON Peloton Interactive Inc. Class A call Reduce -38.6% 5,089,700 $44.3M
SYK Stryker Corp. put Reduce -16.7% 100,000 $36.0M
ENVA Enova International Inc. call Sold out 109,000 $9.1Mbefore exit
KRYS Krystal Biotech Inc. put Reduce -7.2% 50,000 $7.8M
IMAX Imax Corp. call Reduce -83.3% 250,000 $6.4M
GPCR Structure Therapeutics Inc. call New 150,000 $4.1M
KROS Keros Therapeutics Inc. call New 250,000 $4.0M
EGRX Eagle Pharmaceuticals Inc. call Sold out 1,000,000 $3.7Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q3 2024 → Q4 2024

LMND.WS Lemonade Inc.-28 *W EXP 02/09/202 Sold out 507,460 $16Kbefore exit

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 128$1.6BTBBK, BVS, HGV, SVRA, ETON
Q1 2026 125$1.6BTBBK, HGV, SLNO, BVS, PTON
Q4 2025 127$1.7BTBBK, ESTA, HGV, SLNO, XTNT
Q3 2025 127$1.6BESTA, HGV, TBBK, QURE, SLNO
Q2 2025 133$1.4BSLNO, HGV, ESTA, TBBK, XTNT
Q1 2025 126$1.2BSLNO, HGV, ESTA, EOLS, TBBK
Q4 2024 118$1.4BSLNO, ESTA, HGV, PTON, TBBK
Q3 2024 119$1.2BSLNO, ESTA, BVS, PTON, EOLS
Q2 2024Amended 113$994.2MSLNO, ESTA, PTON, EOLS, BVS
Q1 2024 107$1.0BSLNO, ESTA, CASH, EOLS, IMAX