Silence Therapeutics PLC-ADRSLN

13F holders, Q2 2026 (June 30)
72holders +16
20new positions
4sold out
3famous investors
$10.73avg. 13F price*

At the end of Q2 2026, 72 institutions reported holding Silence Therapeutics PLC-ADR (SLN) in their 13F filings, up 16 from Q1 2026. 20 opened new positions and 4 sold out. The largest holders were Siren, L.L.C. ($36.4M), TCG Crossover Management, LLC ($33.3M) and Redmile Group, LLC ($23.8M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Silence Therapeutics PLC-ADR
CUSIP
82686Q101
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 64Q1 2024Q2 2024: 71Q2 2024Q3 2024: 69Q3 2024Q4 2024: 65Q4 2024Q1 2025: 59Q1 2025Q2 2025: 55Q2 2025Q3 2025: 54Q3 2025Q4 2025: 58Q4 2025Q1 2026: 56Q1 2026Q2 2026: 72Q2 2026

Total Exit/New Position Q1 2026 → Q2 2026

InstitutionsTotal Value
New Positions20$33.9M
Exits4$2.3M

All 13F filers, Q1 2026 → Q2 2026: 4,920,752 shares bought and 2,592,873 shares sold, net +2,327,879 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 72 holders

Siren, L.L.C. 0.74% Add +13.7% 3,311,438 $36.4M
TCG Crossover Management, LLC 0.80% No change 3,033,560 $33.3M
Redmile Group, LLC 1.60% No change 2,164,777 $23.8M
Nantahala Capital Management, LLC 0.90% Reduce -37.3% 1,346,731 $14.8M
Citadel Advisors 0.01% Add +7.7% 1,329,625 $14.6M
Nextech Invest Ltd. 0.50% No change 952,400 $10.5M
Millennium Management 0.01% Reduce -15.3% 909,279 $10.0M
Tetragon Partners GP Ltd 1.37% Add +21.3% 764,256 $8.4M
Soleus Capital Management, L.P. 0.24% New 630,000 $6.9M
Balyasny Asset Management L.P. 0.01% New 610,980 $6.7M
5AM Venture Management, LLC 1.82% No change 476,200 $5.2M
Great Point Partners LLC 1.16% Reduce -55.9% 450,000 $4.9M
Morgan Stanley 0.00% Add +515.7% 403,172 $4.4M
Ameriprise Financial Inc. 0.00% New 370,052 $4.1M
Jane Street Group, LLC 0.00% Add +265.8% 369,151 $4.1M
ADAR1 Capital Management, LLC 0.18% Add +96.5% 338,373 $3.7M
SummitTX Capital, L.P. 0.09% New 326,648 $3.6M
Schonfeld Strategic Advisors LLC 0.02% New 269,348 $3.0M
UBS Group AG 0.00% Reduce -1.5% 243,152 $2.7M
Ishara Investments LP 1.79% Reduce -60.6% 55,350 $2.4M
BlackRock, Inc. 0.00% Add +7.4% 219,917 $2.4M
Bank of Montreal 0.00% Reduce -0.6% 201,734 $2.2M
Boothbay Fund Management, LLC 0.04% Reduce -5.1% 198,347 $2.2M
Propel Bio Management, LLC 1.10% New 191,733 $2.1M
Susquehanna International Group, LLP 0.00% Add +60.1% 184,519 $2.0M
Fred Alger Management, LLC 0.01% New 177,000 $1.9M
Ikarian Capital, LLC 0.30% Reduce -4.0% 830,784 $1.8M
Qube Research & Technologies Ltd 0.00% Add +56.8% 163,945 $1.8M
Caption Management, LLC 0.07% New 162,476 $1.8M
BNP Paribas Financial Markets 0.00% Add +7.6% 158,950 $1.7M
Goldman Sachs Group Inc. 0.00% Add +196.9% 155,929 $1.7M
Two Sigma Investments, LP 0.00% Add +646.8% 121,004 $1.3M
HSBC Holdings PLC 0.00% No change 122,834 $1.3M
Quadrature Capital Ltd 0.01% New 118,129 $1.3M
Squarepoint Ops LLC 0.00% Add +29.6% 115,918 $1.3M
XTX Topco Ltd 0.02% Add +1.5% 107,579 $1.2M
M28 Capital Management LP 2.36% No change 101,203 $1.1M
Marshall Wace, LLP 0.00% Reduce -57.5% 72,039 $791K
Birchview Capital, LP 0.37% New 71,218 $782K
Seven Fleet Capital Management LP 0.11% Reduce -61.7% 60,107 $660K
HRT Financial LP 0.00% Add +156.4% 30,748 $337K
Geode Capital Management, LLC 0.00% No change 29,538 $324K
Virtu Financial LLC 0.01% New 25,641 $282K
Bank of America Corp. 0.00% Reduce -15.1% 25,280 $278K
Trexquant Investment LP 0.00% New 23,842 $262K
Verdad Advisers, LP 0.21% New 20,400 $224K
Scientech Research LLC 0.17% New 19,133 $210K
Renaissance Technologies 0.00% New 16,930 $186K
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.05% New 16,334 $179K
Persistent Asset Partners Ltd 0.05% New 15,170 $167K
Raymond James Financial Inc. 0.00% Reduce -40.0% 15,000 $165K
Rhumbline Advisers 0.00% Reduce -0.9% 13,815 $152K
Citigroup Inc. 0.00% Add +620.3% 13,217 $145K
Axq Capital, LP 0.01% New 12,566 $138K
SG Americas Securities, LLC 0.00% Reduce -95.8% 12,056 $132K
Acadian Asset Management LLC 0.00% Add +145.7% 11,836 $129K
GAMMA Investing LLC 0.00% Add +18.1% 11,063 $121K
CenterBook Partners LP 0.01% New 10,416 $114K
China Universal Asset Management Co., Ltd. 0.00% Reduce -10.3% 7,475 $82K
JPMorgan Chase & Co. 0.00% Reduce -49.4% 3,863 $42K
Barclays PLC 0.00% Add +16.4% 3,418 $38K
Jones Financial Companies LLLP 0.00% No change 2,500 $25K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -14.2% 2,101 $23K
Tower Research Capital LLC (TRC) 0.00% Reduce -29.1% 1,639 $18K
Parallel Advisors, LLC 0.00% No change 1,300 $14K
Rialto Wealth Management, LLC 0.00% New 1,021 $11K
GF Fund Management Co. LTD. 0.00% Reduce -6.9% 975 $11K
Steward Partners Investment Advisory, LLC 0.00% No change 100 $1K
Rockefeller Capital Management L.P. 0.00% No change 45 $494
Caitong International Asset Management Co., Ltd 0.00% Add +1266.7% 41 $450
SBI Securities Co., Ltd. 0.00% No change 28 $307
Royal Bank of Canada 0.00% Add +62.5% 26 $0

"% of holder's portfolio" is SLN's weight in each manager's 13F, not the share of Silence Therapeutics PLC-ADR the manager owns.