Nantahala Capital Management, LLC

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 15, 2025), Nantahala Capital Management, LLC reported 126 stock positions worth $1.2 billion. Its top holding was Soleno Therapeutics (SLNO) at 10.4% of the portfolio, followed by Hilton Grand Vacations (HGV, 6.1%) and Establishment Labs (ESTA, 6.0%). Compared with Q4 2024, it opened 18 new positions, sold out of 10, added to 38 and reduced 57. The biggest buy was Hilton Grand Vacations (HGV, shares +15%) and the biggest sale Peloton Interactive Class A (PTON, shares −40%).

Most Recent 13F
Q2 2026
Location
NEW CANAAN, CT
CIK
0001472322
Portfolio Value
$1.2B (Q1 2025)
SEC Filing
0001104659-25-049574 ↗ filed May 15, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B Q1 2024: $1.0B Q1 2024 Q2 2024: $994.2M Q2 2024 Q3 2024: $1.2B Q3 2024 Q4 2024: $1.4B Q4 2024 Q1 2025: $1.2B $1.2B Q1 2025 Q2 2025: $1.4B Q2 2025 Q3 2025: $1.6B Q3 2025 Q4 2025: $1.7B Q4 2025 Q1 2026: $1.6B Q1 2026 Q2 2026: $1.6B Q2 2026

Holdings 126 stocks · $1.2B

SLNO Soleno Therapeutics Inc. 10.38% 1,757,023 $125.5M Reduce -55.3%
HGV Hilton Grand Vacations Inc. 6.15% 1,986,737 $74.3M Add +14.8%
ESTA Establishment Labs Holdings 5.99% 1,774,044 $72.4M Add +7.2%
EOLS Evolus Inc. 3.63% 3,651,343 $43.9M Add +16.6%
TBBK The Bancorp Inc. 3.62% 828,503 $43.8M Reduce -15.0%
BVS Bioventus Inc. Class A 3.12% 4,125,650 $37.7M Add +2.5%
AMRX Amneal Pharmaceuticals Inc. 2.64% 3,808,561 $31.9M Add +3.9%
GOGO Gogo Inc. 2.54% 3,564,797 $30.7M Add +38.5%
CRMT America's Car-Mart Inc. 2.42% 644,686 $29.3M Add +18.4%
QURE Uniqure NV 2.42% 2,755,962 $29.2M Add +12.3%
TITN Titan Machinery Inc. 2.29% 1,621,738 $27.6M Reduce -0.2%
PTON Peloton Interactive Inc. Class A 2.28% 4,361,792 $27.6M Reduce -39.6%
IMAX Imax Corp. 1.98% 908,251 $23.9M Reduce -21.1%
SVRA Savara Inc. 1.85% 8,075,375 $22.4M Add +7.3%
SVC Service Pptys TR 1.74% 8,057,887 $21.0M Reduce -0.4%
ABEO Abeona Therapeutics Inc. 1.38% 3,509,850 $16.7M Reduce -0.6%
KROS Keros Therapeutics Inc. 1.27% 1,506,790 $15.4M Add +64.7%
ETON Eton Pharmaceuticals Inc. 1.26% 1,175,951 $15.3M Add +5.1%
URGN Urogen Pharma Ltd. 1.25% 1,363,399 $15.1M Reduce -0.6%
FOXF Fox Factory Holding Corp. 1.21% 628,648 $14.7M Reduce -1.2%
FULC Fulcrum Therapeutics Inc. 1.15% 4,822,693 $13.9M Add +0.9%
VSTM Verastem Inc. 1.15% 2,298,541 $13.9M Reduce -38.8%
EB Eventbrite Inc. Class A 1.11% 6,381,395 $13.5M Add +7.6%
RDVT Red Violet Inc. 1.06% 341,378 $12.8M Reduce -19.2%
MLYS Mineralys Therapeutics Inc. 1.03% 787,740 $12.5M Add +24.5%
RMR RMR Group Inc./the - A 1.01% 736,202 $12.3M Add +63.3%
RH RH 0.97% 50,158 $11.8M New
ZVRA Zevra Therapeutics Inc. 0.91% 1,471,936 $11.0M Reduce -37.1%
RSVR Reservoir Media Inc. 0.91% 1,442,136 $11.0M Reduce -7.6%
BNTC Benitec Biopharma Inc. 0.90% 838,095 $10.9M No change
AMLX Amylyx Pharmaceuticals Inc. 0.86% 2,934,405 $10.4M Add +102.1%
THRD Third Harmonic Bio Inc. 0.84% 2,938,700 $10.2M Add +486.6%
ABVX Abivax SA-ADR 0.77% 1,482,994 $9.3M Add +3.3%
RDNW Ridenow Group Inc. filed as RUMBLEON INC 0.76% 3,272,845 $9.2M Reduce -0.0%
OPTINOSE INC 0.75% 985,333 $9.0M Reduce -0.1%
EHTH Ehealth Inc. 0.72% 1,311,441 $8.8M Reduce -34.7%
ILPT Industrial Logistics Propert 0.71% 2,506,244 $8.6M Add +18.9%
TRML Tourmaline Bio Inc. 0.67% 532,824 $8.1M Reduce -0.8%
CMPS Compass Pathways PLC 0.67% 2,829,232 $8.1M Add +182.9%
ELUT Elutia Inc. 0.67% 3,184,947 $8.1M Add +11.2%
CNTA Centessa Pharmaceuticals Ltd. 0.66% 554,803 $8.0M Add +8.2%
CDXS Codexis Inc. 0.63% 2,830,619 $7.6M Reduce -0.4%
AURA Aura Biosciences Inc. 0.61% 1,267,697 $7.4M Reduce -0.2%
IRON Disc Medicine Inc. 0.61% 148,391 $7.4M Reduce -1.1%
AVTX Avalo Therapeutics Inc. 0.60% 900,000 $7.2M New
PVLA Palvella Therapeutics Inc. 0.58% 250,062 $7.0M No change
SNDX Syndax Pharmaceuticals Inc. 0.56% 554,503 $6.8M Reduce -1.1%
VMD Viemed Healthcare Inc. 0.56% 932,445 $6.8M Reduce -0.3%
STKS One Group Hospitality Inc. filed as THE ONE GROUP HOSPITALITY IN 0.52% 2,121,084 $6.3M Add +1.6%
NSPR Inspiremd Inc. 0.52% 2,318,017 $6.2M Add +38.4%
RAPT THERAPEUTICS INC 0.51% 5,012,927 $6.1M Add +303.1%
AVR Anteris Technologies Global 0.49% 1,663,666 $5.9M Reduce -0.2%
IWM iShares Russell 2000 ETF 0.48% 29,151 $5.8M Reduce -70.1%
ASSERTIO HOLDINGS INC 0.47% 8,439,762 $5.7M Add +3.6%
UNICYCIVE THERAPEUTICS INC 0.45% 9,391,994 $5.4M Reduce -9.6%
XTNT Xtant Medical Holdings Inc. 0.44% 11,394,000 $5.4M No change
NKTR Nektar Therapeutics 0.44% 7,789,051 $5.3M Reduce -0.3%
COGT Cogent Biosciences Inc. 0.42% 843,489 $5.1M Reduce -1.1%
VTGN Vistagen Therapeutics Inc. 0.41% 1,978,492 $4.9M Reduce -0.2%
NDLS Noodles & Co. 0.41% 4,505,489 $4.9M Reduce -0.1%
ALTG Alta Equipment Group Inc. 0.40% 1,042,769 $4.9M Add +23.4%
XNCR Xencor Inc. 0.40% 456,741 $4.9M New
FOSL Fossil Group Inc. 0.40% 4,189,177 $4.8M Add +25.9%
IKT Inhibikase Therapeutics Inc. 0.40% 2,190,000 $4.8M No change
TELA Tela Bio Inc. 0.39% 3,877,965 $4.7M Add +5.4%
CRGX Cargo Therapeutics Inc. 0.37% 1,100,000 $4.5M New
APYX Apyx Medical Corp. 0.37% 3,258,048 $4.5M Add +2.8%
RCKT Rocket Pharmaceuticals Inc. 0.35% 629,749 $4.2M New
TNGX Tango Therapeutics Inc. 0.34% 2,987,983 $4.1M Add +6.5%
ANEB Anebulo Pharmaceuticals Inc. 0.33% 3,036,325 $3.9M No change
KOS Kosmos Energy Ltd. 0.32% 1,716,593 $3.9M New
ELDN Eledon Pharmaceuticals Inc. 0.32% 1,141,237 $3.9M Reduce -0.6%
AKBA Akebia Therapeutics Inc. 0.32% 2,000,000 $3.8M New
NPCE Neuropace Inc. 0.32% 312,094 $3.8M Reduce -44.5%
RZLT Rezolute Inc. 0.31% 1,291,395 $3.7M Reduce -54.8%
UPB Upstream Bio Inc. 0.30% 594,971 $3.6M Reduce -0.8%
DYN Dyne Therapeutics Inc. 0.30% 345,062 $3.6M New
ATXS Astria Therapeutics Inc. 0.30% 669,530 $3.6M Reduce -0.8%
GAIA Gaia Inc. 0.29% 914,618 $3.5M Reduce -0.0%
THTX Theratechnologies Inc. 0.29% 2,422,563 $3.5M Reduce -9.7%
CMCO Columbus McKinnon Corp. 0.28% 200,000 $3.4M New
DHX Dhi Group Inc. 0.27% 2,374,027 $3.3M Reduce -0.1%
NNBR NN Inc. 0.27% 1,441,416 $3.3M Reduce -1.2%
EYPT Eyepoint Inc. 0.27% 593,091 $3.2M Reduce -1.1%
IRD Opus Genetics Inc. 0.26% 3,157,895 $3.1M New
SRL Scully Royalty Ltd. 0.25% 368,182 $3.0M Reduce -0.1%
SNTI Senti Biosciences Inc. 0.25% 888,000 $3.0M New
SLN Silence Therapeutics PLC-ADR 0.24% 1,042,427 $2.9M Reduce -0.7%
GPCR Structure Therapeutics Inc. 0.24% 168,553 $2.9M Reduce -23.7%
GRCE Grace Therapeutics Inc. 0.22% 1,178,203 $2.7M New
SRZN Surrozen Inc. 0.22% 229,527 $2.7M Add +17.1%
RDI Reading International Inc. Class A 0.22% 1,921,088 $2.7M Reduce -32.9%
SCPH Scpharmaceuticals Inc. 0.22% 995,438 $2.6M Reduce -0.5%
CZR Caesars Entertainment Inc. 0.20% 98,879 $2.5M Reduce -1.1%
ACHV Achieve Life Sciences Inc. 0.20% 898,885 $2.4M Add +37.4%
ACH Accendra Health Inc. filed as OWENS & MINOR INC NEW 0.15% 200,000 $1.8M New
ALTISOURCE PORTFOLIO SOLNS S 0.14% 2,477,312 $1.7M Add +16.4%
NVNO Envveno Medical Corporation 0.13% 594,661 $1.6M Reduce -0.4%
EDSA Edesa Biotech Inc. 0.13% 625,000 $1.5M New
KOD Kodiak Sciences Inc. 0.12% 530,713 $1.5M Add +99.1%

Show all 126 holdings

Options reported separately and not counted above: IWM puts ($608.4M), HYG puts ($276.1M), QQQ puts ($140.7M), XBI puts ($97.3M), HLF calls ($50.1M), SLNO puts ($42.9M), PTON calls ($26.5M), HGV calls ($21.5M), LYV puts ($17.0M), CZR calls ($12.5M), RDNW calls ($4.8M), GPCR calls ($2.6M), and 4 more.

Other holdings (3): bonds, preferreds, convertibles and warrants · $30K (not counted above)
SecurityClassShares / PrincipalValueChange
IMTXW Immatics NV -CW *W EXP 07/01/202 248,506$28KNo change
PERFF Perfect Corp. *W EXP 10/28/202 16,075$2KNo change
GFAIW Guardforce AI Co. Ltd. -CW26 *W EXP 10/01/202 154,205$182No change

Total filed on the 13F, all lines: $1.2B.

Portfolio Sells Q4 2024 → Q1 2025

PTON Peloton Interactive Inc. Class A Reduce -39.6% 2.28% −2.12
SLNO Soleno Therapeutics Inc. Reduce -55.3% 10.38% −1.97
BKSY Blacksky Technology Inc. Sold out 0.00% −1.04
IWM iShares Russell 2000 ETF Reduce -70.1% 0.48% −1.03
PAYO Payoneer Global Inc. Reduce -90.4% 0.09% −0.99
CASH Pathward Financial Inc. Sold out 0.00% −0.98
RZLT Rezolute Inc. Reduce -54.8% 0.31% −0.67
EHTH Ehealth Inc. Reduce -34.7% 0.72% −0.60
RDNW Ridenow Group Inc. Reduce -0.0% 0.76% −0.48
ZVRA Zevra Therapeutics Inc. Reduce -37.1% 0.91% −0.45
UPB Upstream Bio Inc. Reduce -0.8% 0.30% −0.39
LXRX Lexicon Pharmaceuticals Inc. Reduce -93.0% 0.02% −0.32
CDXS Codexis Inc. Reduce -0.4% 0.63% −0.32
IMTX Immatics NV Sold out 0.00% −0.29
SLN Silence Therapeutics PLC-ADR Reduce -0.7% 0.24% −0.26
OCUL Ocular Therapeutix Inc. Sold out 0.00% −0.26
MIST Milestone Pharmaceuticals Inc. Sold out 0.00% −0.24
VSTM Verastem Inc. Reduce -38.8% 1.15% −0.21
ZYXIQ Zynex Inc. Reduce -0.5% 0.09% −0.19
GPCR Structure Therapeutics Inc. Reduce -23.7% 0.24% −0.18
AVR Anteris Technologies Global Reduce -0.2% 0.49% −0.16
FOXF Fox Factory Holding Corp. Reduce -1.2% 1.21% −0.13
UNICYCIVE THERAPEUTICS INC Reduce -9.6% 0.45% −0.13
ATXS Astria Therapeutics Inc. Reduce -0.8% 0.30% −0.13
NPCE Neuropace Inc. Reduce -44.5% 0.32% −0.12
AURA Aura Biosciences Inc. Reduce -0.2% 0.61% −0.12
BCOV Brightcove Sold out 0.00% −0.11
MAX Mediaalpha Inc. Class A Sold out 0.00% −0.10
TYRA Tyra Biosciences Inc. Sold out 0.00% −0.10
TRML Tourmaline Bio Inc. Reduce -0.8% 0.67% −0.09
AEROVATE THERAPEUTICS INC Sold out 0.00% −0.09
IMAX Imax Corp. Reduce -21.1% 1.98% −0.08
RSVR Reservoir Media Inc. Reduce -7.6% 0.91% −0.08
NKTR Nektar Therapeutics Reduce -0.3% 0.44% −0.07
NNBR NN Inc. Reduce -1.2% 0.27% −0.06
IRON Disc Medicine Inc. Reduce -1.1% 0.61% −0.06
THTX Theratechnologies Inc. Reduce -9.7% 0.29% −0.05
DRIO Dariohealth Corp. Reduce -30.8% 0.09% −0.05
COGT Cogent Biosciences Inc. Reduce -1.1% 0.42% −0.05
EYPT Eyepoint Inc. Reduce -1.1% 0.27% −0.05
RDI Reading International Inc. Class A Reduce -32.9% 0.22% −0.04
LAZYDAYS HLDGS INC Reduce -66.3% 0.01% −0.03
SCPH Scpharmaceuticals Inc. Reduce -0.5% 0.22% −0.03
CZR Caesars Entertainment Inc. Reduce -1.1% 0.20% −0.03
PERF Perfect Corp. Reduce -1.0% 0.07% −0.03
EWTX Edgewise Therapeutics Inc. Sold out 0.00% −0.03
DHX Dhi Group Inc. Reduce -0.1% 0.27% −0.02
SGRP Spar Group Inc. Reduce -0.2% 0.07% −0.02
OKUR Onkure Therapeutics Inc. Class A Reduce -1.0% 0.02% −0.01
EVOK Evoke Pharma Inc. Reduce -0.0% 0.03% −0.01

Portfolio Buys Q4 2024 → Q1 2025

HGV Hilton Grand Vacations Inc. Add +14.8% 6.15% +1.43
EOLS Evolus Inc. Add +16.6% 3.63% +1.22
GOGO Gogo Inc. Add +38.5% 2.54% +1.08
RH RH New 0.97% +0.97
ESTA Establishment Labs Holdings Add +7.2% 5.99% +0.66
AMRX Amneal Pharmaceuticals Inc. Add +3.9% 2.64% +0.61
AVTX Avalo Therapeutics Inc. New 0.60% +0.60
MLYS Mineralys Therapeutics Inc. Add +24.5% 1.03% +0.49
THRD Third Harmonic Bio Inc. Add +486.6% 0.84% +0.48
AMLX Amylyx Pharmaceuticals Inc. Add +102.1% 0.86% +0.48
CRMT America's Car-Mart Inc. Add +18.4% 2.42% +0.47
CMPS Compass Pathways PLC Add +182.9% 0.67% +0.40
XNCR Xencor Inc. New 0.40% +0.40
CRGX Cargo Therapeutics Inc. New 0.37% +0.37
RAPT THERAPEUTICS INC Add +303.1% 0.51% +0.37
RMR RMR Group Inc./the - A Add +63.3% 1.01% +0.36
RCKT Rocket Pharmaceuticals Inc. New 0.35% +0.35
KOS Kosmos Energy Ltd. New 0.32% +0.32
AKBA Akebia Therapeutics Inc. New 0.32% +0.32
DYN Dyne Therapeutics Inc. New 0.30% +0.30
CMCO Columbus McKinnon Corp. New 0.28% +0.28
KROS Keros Therapeutics Inc. Add +64.7% 1.27% +0.26
IRD Opus Genetics Inc. New 0.26% +0.26
SNTI Senti Biosciences Inc. New 0.25% +0.25
SVRA Savara Inc. Add +7.3% 1.85% +0.23
GRCE Grace Therapeutics Inc. New 0.22% +0.22
ETON Eton Pharmaceuticals Inc. Add +5.1% 1.26% +0.22
NSPR Inspiremd Inc. Add +38.4% 0.52% +0.21
ILPT Industrial Logistics Propert Add +18.9% 0.71% +0.17
BVS Bioventus Inc. Class A Add +2.5% 3.12% +0.16
ACH Accendra Health Inc. New 0.15% +0.15
EDSA Edesa Biotech Inc. New 0.13% +0.13
STKS One Group Hospitality Inc. Add +1.6% 0.52% +0.10
SLDB Solid Biosciences Inc. New 0.09% +0.09
HLF Herbalife Ltd. New 0.07% +0.07
OLPX Olaplex Holdings Inc. New 0.07% +0.07
ACU Acme United Corp. New 0.07% +0.07
CNTA Centessa Pharmaceuticals Ltd. Add +8.2% 0.66% +0.06
ALTISOURCE PORTFOLIO SOLNS S Add +16.4% 0.14% +0.04
ACHV Achieve Life Sciences Inc. Add +37.4% 0.20% +0.04
ABVX Abivax SA-ADR Add +3.3% 0.77% +0.03
BIOMX INC Add +44.1% 0.11% +0.03
SRZN Surrozen Inc. Add +17.1% 0.22% +0.02
FBIO Fortress Biotech Inc. Add +159.3% 0.04% +0.02
PLCE The Children's Place Inc. Add +94.5% 0.04% +0.02
APYX Apyx Medical Corp. Add +2.8% 0.37% +0.02
ALTG Alta Equipment Group Inc. Add +23.4% 0.40% +0.02
FOSL Fossil Group Inc. Add +25.9% 0.40% +0.01
ASSERTIO HOLDINGS INC Add +3.6% 0.47% −0.03
KOD Kodiak Sciences Inc. Add +99.1% 0.12% −0.06

Options Activity Q4 2024 → Q1 2025

IWM iShares Russell 2000 ETF put Add +27.1% 3,050,000 $608.4M
HYG Ishr Ibx Usd Hiyld CB ETF-Ui put New 3,500,000 $276.1M
QQQ Invesco QQQ Trust Series 1 put New 300,000 $140.7M
LLY Eli Lilly & Co. put Sold out 160,000 $123.5Mbefore exit
XBI SS SPDR S&P Biotech ETF put Reduce -4.0% 1,200,000 $97.3M
HLF Herbalife Ltd. call Add +625.0% 5,800,000 $50.1M
SLNO Soleno Therapeutics Inc. put New 600,000 $42.9M
SYK Stryker Corp. put Sold out 100,000 $36.0Mbefore exit
PTON Peloton Interactive Inc. Class A call Reduce -17.5% 4,200,000 $26.5M
HGV Hilton Grand Vacations Inc. call New 575,000 $21.5M
LYV Live Nation Entertainment Inc. put New 130,300 $17.0M
CZR Caesars Entertainment Inc. call Add +150.0% 500,000 $12.5M
KRYS Krystal Biotech Inc. put Sold out 50,000 $7.8Mbefore exit
IMAX Imax Corp. call Sold out 250,000 $6.4Mbefore exit
QURE Uniqure NV call Sold out 201,000 $3.5Mbefore exit
EOLS Evolus Inc. call New 100,000 $1.2M

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q4 2024 → Q1 2025

TCBWF TC Biopharm Holdings Ltd. *W EXP 02/10/202 Sold out 235,294 $2Kbefore exit

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 128$1.6BTBBK, BVS, HGV, SVRA, ETON
Q1 2026 125$1.6BTBBK, HGV, SLNO, BVS, PTON
Q4 2025 127$1.7BTBBK, ESTA, HGV, SLNO, XTNT
Q3 2025 127$1.6BESTA, HGV, TBBK, QURE, SLNO
Q2 2025 133$1.4BSLNO, HGV, ESTA, TBBK, XTNT
Q1 2025 126$1.2BSLNO, HGV, ESTA, EOLS, TBBK
Q4 2024 118$1.4BSLNO, ESTA, HGV, PTON, TBBK
Q3 2024 119$1.2BSLNO, ESTA, BVS, PTON, EOLS
Q2 2024Amended 113$994.2MSLNO, ESTA, PTON, EOLS, BVS
Q1 2024 107$1.0BSLNO, ESTA, CASH, EOLS, IMAX