Alnylam PharmaceuticalsALNY
13F holders, Q1 2025 (March 31)626holders +32
93new positions
65sold out
7famous investors
$269.11avg. 13F price*
At the end of Q1 2025, 626 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 32 from Q4 2024. 93 opened new positions and 65 sold out. The largest holders were Capital World Investors ($4.5B), FMR LLC ($4.1B) and Vanguard Group Inc. ($3.5B). 7 famous investors held it, including George Soros (0.4% of Soros Fund Management's portfolio), Steve Cohen (0.2% of Point72 Asset Management's portfolio) and Cliff Asness (0.2% of AQR Capital Management's portfolio).
- Company
- Alnylam Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 02043Q107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 93 | $498.6M |
| Exits | 65 | $442.9M |
All 13F filers, Q4 2024 → Q1 2025: 8,631,310 shares bought and 7,502,279 shares sold, net +1,129,031 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 626 holders
| Capital World Investors | 0.73% | Add +0.9% | 16,749,623 | $4.5B |
| FMR LLC | 0.26% | Add +13.5% | 15,309,860 | $4.1B |
| Vanguard Group Inc. | 0.06% | Add +2.5% | 13,056,605 | $3.5B |
| BlackRock, Inc. | 0.05% | Reduce -3.3% | 9,559,382 | $2.6B |
| Capital Research Global Investors | 0.42% | Add +2.7% | 7,154,728 | $1.9B |
| Regeneron Pharmaceuticals, Inc. | 97.23% | No change | 4,444,445 | $1.2B |
| T. Rowe Price Investment Management, Inc. | 0.79% | Add +0.8% | 4,418,145 | $1.2B |
| Baillie Gifford & Co. | 0.86% | Reduce -9.5% | 3,657,607 | $987.6M |
| T. Rowe Price Associates Inc. | 0.12% | Add +5.6% | 3,505,168 | $946.5M |
| State Street Corp. | 0.04% | Reduce -1.6% | 3,366,583 | $909.0M |
| Dodge & Cox | 0.52% | Reduce -5.3% | 3,351,762 | $905.0M |
| Wellington Management Group LLP | 0.14% | Reduce -37.8% | 2,610,986 | $705.0M |
| Geode Capital Management, LLC | 0.05% | Add +5.3% | 2,322,834 | $625.8M |
| JPMorgan Chase & Co. | 0.05% | Reduce -1.4% | 2,218,872 | $599.1M |
| Norges Bank | 0.08% | Reduce -13.0% | 2,136,024 | $576.8M |
| American Century Companies Inc. | 0.29% | Add +9.8% | 1,760,435 | $475.4M |
| Orbis Allan Gray Ltd | 2.52% | Add +11.0% | 1,634,923 | $441.5M |
| Winslow Capital Management, LLC | 1.28% | Add +16.3% | 1,187,178 | $320.6M |
| Bank of America Corp. | 0.03% | Add +154.3% | 1,064,573 | $287.5M |
| Invesco Ltd. | 0.05% | Add +63.6% | 913,792 | $246.7M |
| Legal & General Group Plc | 0.06% | Add +6.3% | 881,111 | $237.9M |
| Northern Trust Corp. | 0.03% | Reduce -1.6% | 865,020 | $233.6M |
| AQR Capital Management | 0.22% | Add +1.8% | 828,344 | $217.0M |
| Bellevue Group AG | 4.65% | Reduce -0.3% | 768,147 | $207.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.05% | Add +3.6% | 736,111 | $198.8M |
| Morgan Stanley | 0.01% | Reduce -11.8% | 641,765 | $173.3M |
| Deutsche Bank AG | 0.06% | Add +3.7% | 576,993 | $155.8M |
| Nuveen, LLC | 0.05% | — | 883,374 | $148.7M |
| Charles Schwab Investment Management Inc. | 0.03% | Add +6.4% | 546,642 | $147.6M |
| Loomis Sayles & Co. L P | 0.19% | Reduce -1.1% | 497,484 | $134.3M |
| TD Asset Management Inc | 0.12% | Reduce -3.5% | 486,584 | $131.4M |
| Pictet Asset Management Holding SA | 0.14% | Add +11.7% | 480,967 | $129.7M |
| Bank of New York Mellon Corp | 0.03% | Reduce -0.9% | 474,832 | $128.2M |
| Franklin Resources Inc. | 0.04% | Add +10.7% | 458,314 | $123.8M |
| Amundi | 0.04% | Reduce -8.3% | 454,995 | $119.3M |
| Goldman Sachs Group Inc. | 0.02% | Add +38.1% | 423,367 | $114.3M |
| Swiss National Bank | 0.07% | Add +0.4% | 364,200 | $98.3M |
| Orbimed Advisors LLC | 2.24% | Reduce -16.7% | 346,100 | $93.5M |
| Gilder Gagnon Howe & Co. LLC | 1.22% | Reduce -5.4% | 345,575 | $93.3M |
| Royal Bank of Canada | 0.02% | Add +8.7% | 337,231 | $91.1M |
| Qube Research & Technologies Ltd | 0.14% | Reduce -31.9% | 330,347 | $89.2M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -7.2% | 309,819 | $83.6M |
| Jennison Associates LLC | 0.06% | Add +19.0% | 309,219 | $83.5M |
| Point72 Asset Management | 0.24% | New | 300,635 | $81.2M |
| Wells Fargo & Company | 0.02% | Add +8.3% | 300,080 | $81.0M |
| Sumitomo Mitsui Trust Group, Inc. | 0.06% | Add +1.7% | 291,476 | $78.7M |
| D. E. Shaw & Co. | 0.10% | Reduce -20.2% | 289,862 | $78.3M |
| Millennium Management | 0.08% | Reduce -13.8% | 287,337 | $77.6M |
| Royal London Asset Management Ltd. | 0.18% | Add +1.9% | 286,943 | $77.5M |
| Adage Capital Partners Gp, L.L.C. | 0.14% | Add +203.2% | 282,184 | $76.2M |
| Polar Capital Holdings Plc | 0.46% | Reduce -9.7% | 280,000 | $75.6M |
| UBS Group AG | 0.02% | Reduce -3.9% | 278,638 | $75.2M |
| Sei Investments Co. | 0.10% | Add +4.3% | 277,369 | $74.9M |
| Two Sigma Advisers, LP | 0.17% | Add +250.0% | 275,800 | $74.5M |
| Raymond James Financial Inc. | 0.03% | Reduce -3.1% | 268,970 | $72.6M |
| Marshall Wace, LLP | 0.10% | Reduce -29.0% | 268,932 | $72.6M |
| Federated Hermes, Inc. | 0.15% | Add +5.8% | 264,173 | $71.3M |
| Allspring Global Investments Holdings, LLC | 0.12% | New | 270,924 | $69.3M |
| Candriam S.C.A. | 0.43% | Reduce -11.5% | 249,919 | $67.5M |
| Allianz Asset Management GmbH | 0.09% | Add +100.7% | 218,503 | $59.0M |
| Aberdeen Group plc | 0.11% | Add +12.9% | 215,385 | $57.1M |
| California Public Employees Retirement System | 0.04% | Reduce -1.3% | 201,481 | $54.4M |
| California State Teachers Retirement System | 0.07% | Add +0.6% | 197,443 | $53.3M |
| Two Sigma Investments, LP | 0.12% | Add +84.3% | 197,415 | $53.3M |
| Citigroup Inc. | 0.04% | Add +124.1% | 194,734 | $52.6M |
| Westfield Capital Management Co. LP | 0.25% | Reduce -11.1% | 192,172 | $51.9M |
| Worldquant Millennium Advisors LLC | 0.33% | Add +27.2% | 191,105 | $51.6M |
| Rhumbline Advisers | 0.05% | Add +1.1% | 181,463 | $49.0M |
| Janus Henderson Group PLC | 0.03% | Reduce -13.5% | 181,649 | $48.8M |
| First Trust Advisors LP | 0.04% | Reduce -45.0% | 180,460 | $48.7M |
| Sofinnova Investments, Inc. | 3.59% | Add +59.9% | 176,181 | $47.6M |
| National Pension Service | 0.05% | Add +8.9% | 173,659 | $46.9M |
| Prudential Financial Inc. | 0.07% | Add +817.2% | 172,006 | $46.4M |
| SCS Capital Management LLC | 0.59% | New | 171,077 | $46.2M |
| CIBC Private Wealth Group LLC | 0.10% | Add +1.1% | 205,511 | $46.1M |
| Eventide Asset Management, LLC | 0.90% | Reduce -30.8% | 166,450 | $44.9M |
| ANTIPODES PARTNERS Ltd | 1.35% | Add +19.3% | 159,554 | $43.1M |
| Woodline Partners LP | 0.27% | New | 156,464 | $42.2M |
| Jacobs Levy Equity Management, Inc. | 0.16% | New | 152,970 | $41.3M |
| Deerfield Management Company, L.P. | 0.89% | Reduce -0.1% | 145,000 | $39.2M |
| 1832 Asset Management L.P. | 0.07% | New | 144,045 | $38.9M |
| Rock Springs Capital Management LP | 2.22% | Reduce -44.1% | 143,250 | $38.7M |
| SG Americas Securities, LLC | 0.12% | Add +7876.0% | 132,960 | $35.9M |
| Russell Investments Group, Ltd. | 0.05% | Add +76.6% | 129,196 | $34.9M |
| State Board of Administration of Florida Retirement System | 0.07% | No change | 125,240 | $33.8M |
| Capital International Sarl | 0.74% | Add +5.2% | 121,160 | $32.7M |
| Casdin Capital, LLC | 2.65% | Reduce -14.3% | 120,000 | $32.4M |
| FIL Ltd | 0.03% | Add +434.1% | 117,862 | $31.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.07% | Reduce -5.3% | 117,720 | $31.8M |
| Handelsbanken Fonder AB | 0.13% | Add +114.7% | 116,683 | $31.5M |
| HighTower Advisors, LLC | 0.04% | Reduce -1.3% | 113,857 | $30.7M |
| DekaBank Deutsche Girozentrale | 0.06% | Reduce -0.1% | 113,042 | $30.0M |
| Mitsubishi UFJ Trust & Banking Corp | 0.08% | Reduce -5.2% | 110,665 | $29.9M |
| Ameriprise Financial Inc. | 0.01% | Reduce -14.8% | 109,136 | $29.5M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.03% | Add +11.8% | 105,879 | $28.6M |
| Korea Investment CORP | 0.07% | Add +13.0% | 105,759 | $28.6M |
| Robeco Institutional Asset Management B.V. | 0.05% | Add +3.5% | 103,481 | $27.9M |
| Frontier Capital Management Co. LLC | 0.30% | Reduce -2.2% | 102,420 | $27.7M |
| Manufacturers Life Insurance Company, The | 0.03% | Reduce -9.4% | 98,869 | $26.7M |
| Jane Street Group, LLC | 0.05% | Reduce -38.6% | 98,551 | $26.6M |
"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.