Alnylam PharmaceuticalsALNY
13F holders, Q3 2025 (September 30)823holders +169
217new positions
47sold out
9famous investors
$455.85avg. 13F price*
At the end of Q3 2025, 823 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 169 from Q2 2025. 217 opened new positions and 47 sold out. The largest holders were FMR LLC ($7.6B), Capital World Investors ($7.5B) and Vanguard Group Inc. ($6.2B). 9 famous investors held it, including Cliff Asness (0.2% of AQR Capital Management's portfolio), Israel Englander (0.2% of Millennium Management's portfolio) and Ken Griffin (0.1% of Citadel Advisors's portfolio).
- Company
- Alnylam Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 02043Q107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 217 | $1.0B |
| Exits | 47 | $193.0M |
All 13F filers, Q2 2025 → Q3 2025: 15,107,698 shares bought and 15,411,636 shares sold, net −303,938 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 823 holders
| FMR LLC | 0.40% | Add +6.1% | 16,767,625 | $7.6B |
| Capital World Investors | 1.03% | Reduce -2.2% | 16,434,253 | $7.5B |
| Vanguard Group Inc. | 0.09% | Add +2.0% | 13,565,452 | $6.2B |
| BlackRock, Inc. | 0.08% | Reduce -0.8% | 9,903,601 | $4.5B |
| Capital Research Global Investors | 0.62% | Add +0.4% | 7,222,840 | $3.3B |
| JPMorgan Chase & Co. | 0.13% | Add +120.4% | 4,543,770 | $2.1B |
| State Street Corp. | 0.05% | Reduce -2.9% | 3,081,475 | $1.4B |
| Baillie Gifford & Co. | 0.94% | Reduce -8.0% | 2,789,356 | $1.3B |
| Geode Capital Management, LLC | 0.07% | Add +4.2% | 2,499,242 | $1.1B |
| Dodge & Cox | 0.57% | Reduce -27.4% | 2,321,230 | $1.1B |
| T. Rowe Price Investment Management, Inc. | 0.61% | Reduce -49.2% | 2,173,984 | $991.3M |
| Orbis Allan Gray Ltd | 3.82% | Reduce -8.0% | 1,950,962 | $889.6M |
| Wellington Management Group LLP | 0.15% | Reduce -12.0% | 1,826,321 | $832.8M |
| T. Rowe Price Associates Inc. | 0.09% | Reduce -42.8% | 1,800,294 | $820.9M |
| American Century Companies Inc. | 0.38% | Reduce -8.5% | 1,641,441 | $748.5M |
| Bank of America Corp. | 0.05% | Add +19.2% | 1,498,491 | $683.3M |
| Invesco Ltd. | 0.11% | Add +10.4% | 1,481,842 | $675.7M |
| Regeneron Pharmaceuticals, Inc. | 90.64% | Reduce -68.7% | 1,392,303 | $634.9M |
| Arrowstreet Capital, Limited Partnership | 0.39% | Add +698.8% | 1,355,609 | $618.2M |
| Jane Street Group, LLC | 0.52% | Add +4094.7% | 958,750 | $437.2M |
| Two Sigma Advisers, LP | 0.81% | Add +235.4% | 892,500 | $407.0M |
| Legal & General Group Plc | 0.09% | Add +1.7% | 887,780 | $404.8M |
| Northern Trust Corp. | 0.05% | Add +0.2% | 833,151 | $379.9M |
| Qube Research & Technologies Ltd | 0.52% | New | 811,278 | $369.9M |
| AQR Capital Management | 0.22% | Add +295.2% | 744,008 | $336.0M |
| Morgan Stanley | 0.02% | Reduce -5.8% | 726,061 | $331.1M |
| Franklin Resources Inc. | 0.08% | Add +18.7% | 714,012 | $325.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.07% | Reduce -26.1% | 708,564 | $323.1M |
| Macquarie Group Ltd. | 0.35% | Add +8.0% | 648,344 | $295.6M |
| Clearbridge Investments, LLC | 0.21% | Add +11.7% | 622,435 | $283.8M |
| Charles Schwab Investment Management Inc. | 0.04% | Add +8.2% | 618,770 | $282.2M |
| Deutsche Bank AG | 0.09% | Reduce -6.6% | 606,320 | $276.5M |
| Two Sigma Investments, LP | 0.44% | Add +73.6% | 595,926 | $271.7M |
| Nuveen, LLC | 0.07% | Reduce -24.1% | 587,821 | $268.0M |
| Susquehanna International Group, LLP | 0.39% | Add +177.4% | 577,632 | $263.4M |
| Federated Hermes, Inc. | 0.44% | Add +69.9% | 550,104 | $250.8M |
| Millennium Management | 0.21% | Add +508.0% | 549,931 | $250.8M |
| Goldman Sachs Group Inc. | 0.04% | Reduce -1.3% | 538,346 | $245.5M |
| Marshall Wace, LLP | 0.26% | Add +113.1% | 508,371 | $231.8M |
| Loomis Sayles & Co. L P | 0.27% | Add +2.7% | 500,672 | $228.3M |
| UBS Group AG | 0.04% | Reduce -10.2% | 488,204 | $222.6M |
| 1832 Asset Management L.P. | 0.35% | Add +105.7% | 459,345 | $209.5M |
| Bellevue Group AG | 4.23% | Reduce -34.0% | 446,524 | $203.6M |
| Royal Bank of Canada | 0.04% | Add +1.4% | 436,758 | $199.2M |
| Bank of New York Mellon Corp | 0.03% | Reduce -2.3% | 419,783 | $191.4M |
| Jacobs Levy Equity Management, Inc. | 0.74% | Add +2221.7% | 410,342 | $187.1M |
| Pictet Asset Management Holding SA | 0.17% | Reduce -16.6% | 387,546 | $176.0M |
| Amundi | 0.06% | Reduce -2.5% | 384,272 | $173.7M |
| Raymond James Financial Inc. | 0.06% | Add +39.5% | 377,294 | $172.0M |
| Swiss National Bank | 0.10% | Reduce -4.6% | 375,800 | $171.4M |
| Voya Investment Management LLC | 0.19% | Add +76.9% | 373,356 | $170.3M |
| Voloridge Investment Management, LLC | 0.55% | Add +4532.6% | 356,806 | $162.7M |
| Massachusetts Financial Services Co. | 0.05% | New | 356,529 | $162.6M |
| Gilder Gagnon Howe & Co. LLC | 1.53% | Reduce -2.3% | 329,321 | $150.2M |
| Sumitomo Mitsui Trust Group, Inc. | 0.08% | Add +7.1% | 314,452 | $143.4M |
| Allspring Global Investments Holdings, LLC | 0.23% | Reduce -0.5% | 310,804 | $143.2M |
| TD Asset Management Inc | 0.12% | Reduce -29.2% | 312,517 | $142.5M |
| Jennison Associates LLC | 0.08% | Reduce -12.9% | 304,863 | $139.0M |
| Orbimed Advisors LLC | 3.30% | Reduce -11.8% | 301,600 | $137.5M |
| HRT Financial LP | 0.49% | Add +1529.4% | 291,449 | $132.9M |
| Susquehanna Advisors Group, Inc. | 5.11% | New | 286,100 | $130.5M |
| Wells Fargo & Company | 0.03% | Reduce -12.8% | 280,568 | $127.9M |
| KBC Group NV | 0.30% | Add +41.2% | 273,352 | $124.6M |
| Royal London Asset Management Ltd. | 0.25% | Reduce -0.7% | 257,313 | $117.3M |
| Polar Capital Holdings Plc | 0.56% | Add +5.9% | 251,460 | $114.7M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -20.8% | 241,934 | $110.3M |
| California Public Employees Retirement System | 0.06% | Add +8.5% | 229,641 | $104.7M |
| Ameriprise Financial Inc. | 0.02% | Add +16.6% | 225,879 | $103.0M |
| Citadel Advisors | 0.08% | Reduce -63.1% | 221,843 | $101.2M |
| Worldquant Millennium Advisors LLC | 0.43% | Add +88.0% | 220,634 | $100.6M |
| CIBC Private Wealth Group LLC | 0.17% | Reduce -1.9% | 214,213 | $97.7M |
| Candriam S.C.A. | 0.51% | Reduce -10.8% | 212,416 | $96.9M |
| First Trust Advisors LP | 0.07% | Reduce -16.4% | 210,383 | $95.9M |
| California State Teachers Retirement System | 0.10% | Add +2.2% | 203,778 | $92.9M |
| D. E. Shaw & Co. | 0.08% | Add +84.2% | 199,417 | $90.9M |
| Korea Investment CORP | 0.18% | Add +77.6% | 196,912 | $89.8M |
| Rhumbline Advisers | 0.07% | Reduce -2.0% | 196,497 | $89.6M |
| Russell Investments Group, Ltd. | 0.10% | Add +109.7% | 195,916 | $89.2M |
| Victory Capital Management Inc. | 0.05% | Add +15.4% | 180,349 | $82.2M |
| National Pension Service | 0.06% | Add +1.3% | 177,238 | $80.8M |
| Los Angeles Capital Management LLC | 0.25% | Add +136.5% | 159,394 | $72.7M |
| Aberdeen Group plc | 0.11% | Reduce -28.0% | 157,396 | $71.7M |
| Handelsbanken Fonder AB | 0.23% | Add +0.0% | 155,369 | $70.8M |
| BNP Paribas Financial Markets | 0.06% | Add +19.0% | 153,039 | $69.8M |
| SCS Capital Management LLC | 0.75% | Reduce -11.7% | 150,668 | $68.7M |
| Squarepoint Ops LLC | 0.14% | Add +5851.1% | 145,565 | $66.4M |
| Canada Pension Plan Investment Board | 0.04% | Add +283.8% | 136,331 | $62.2M |
| Janus Henderson Group PLC | 0.03% | Reduce -9.7% | 135,855 | $61.9M |
| FIL Ltd | 0.05% | Reduce -8.4% | 135,484 | $61.8M |
| Neuberger Berman Group LLC | 0.04% | Add +31.8% | 130,544 | $59.5M |
| Capital International Sarl | 1.02% | Add +1.1% | 129,702 | $59.1M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.04% | Add +8.1% | 120,787 | $55.1M |
| Envestnet Asset Management Inc. | 0.02% | Add +24.2% | 118,964 | $54.2M |
| Frontier Capital Management Co. LLC | 0.49% | Add +15.4% | 118,878 | $54.2M |
| Congress Asset Management Co. | 0.36% | New | 118,800 | $54.2M |
| State Board of Administration of Florida Retirement System | 0.09% | Reduce -7.7% | 117,226 | $53.5M |
| Robeco Institutional Asset Management B.V. | 0.07% | Add +17.3% | 113,074 | $51.6M |
| HighTower Advisors, LLC | 0.06% | Add +1.2% | 110,624 | $50.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.09% | Reduce -3.3% | 110,552 | $50.4M |
| DekaBank Deutsche Girozentrale | 0.08% | No change | 113,193 | $50.3M |
"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.