Alnylam PharmaceuticalsALNY

13F holders, Q4 2024 (December 31)
594holders +26
62new positions
61sold out
6famous investors
$235.24avg. 13F price*

At the end of Q4 2024, 594 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 26 from Q3 2024. 62 opened new positions and 61 sold out. The largest holders were Capital World Investors ($3.9B), FMR LLC ($3.2B) and Vanguard Group Inc. ($3.0B). 6 famous investors held it, including Cliff Asness (0.2% of AQR Capital Management's portfolio), David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.1% of Millennium Management's portfolio).

Company
Alnylam Pharmaceuticals Inc.
Sector
Health Care
CUSIP
02043Q107
Latest filing quarter
Q2 2026

History

Number of 13F holders

02004006008001,000 Q1 2024: 498Q1 2024Q2 2024: 523Q2 2024Q3 2024: 568Q3 2024Q4 2024: 594Q4 2024Q1 2025: 626Q1 2025Q2 2025: 654Q2 2025Q3 2025: 823Q3 2025Q4 2025: 852Q4 2025Q1 2026: 793Q1 2026Q2 2026: 793Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions62$218.7M
Exits61$173.1M

All 13F filers, Q3 2024 → Q4 2024: 8,045,977 shares bought and 8,840,820 shares sold, net −794,843 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 594 holders

Capital World Investors 0.59% Add +0.6% 16,600,525 $3.9B
FMR LLC 0.19% Reduce -8.1% 13,485,903 $3.2B
Vanguard Group Inc. 0.05% Add +0.8% 12,733,399 $3.0B
BlackRock, Inc. 0.05% Add +1.8% 9,885,257 $2.3B
Capital Research Global Investors 0.34% Add +32.9% 6,968,513 $1.6B
Regeneron Pharmaceuticals, Inc. 95.54% — 4,444,445 $1.0B
T. Rowe Price Investment Management, Inc. 0.64% Add +39.7% 4,384,449 $1.0B
Wellington Management Group LLP 0.18% Reduce -15.3% 4,196,623 $987.5M
Baillie Gifford & Co. 0.73% Reduce -17.3% 4,040,259 $950.7M
Dodge & Cox 0.49% Reduce -2.3% 3,540,262 $833.1M
State Street Corp. 0.03% Reduce -1.3% 3,422,877 $805.5M
T. Rowe Price Associates Inc. 0.09% Reduce -3.8% 3,319,385 $781.1M
Norges Bank 0.08% Add +3.4% 2,456,082 $577.9M
JPMorgan Chase & Co. 0.04% Add +4.0% 2,250,060 $529.5M
Geode Capital Management, LLC 0.04% Add +2.8% 2,206,800 $518.4M
American Century Companies Inc. 0.22% Add +0.7% 1,604,024 $377.4M
Orbis Allan Gray Ltd 1.86% Add +16.1% 1,472,802 $346.6M
Capital International Investors 0.06% Reduce -64.3% 1,418,602 $333.8M
Winslow Capital Management, LLC 0.85% Add +6.1% 1,020,567 $240.1M
Northern Trust Corp. 0.03% Add +19.6% 878,860 $206.8M
Legal & General Group Plc 0.05% Add +4.7% 828,917 $195.1M
AQR Capital Management 0.25% Add +60.9% 813,356 $191.4M
Bellevue Group AG 3.49% Reduce -4.8% 770,268 $181.3M
Morgan Stanley 0.01% Add +17.6% 727,224 $171.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.04% Add +0.6% 710,598 $167.2M
Invesco Ltd. 0.02% Reduce -19.7% 558,490 $131.4M
Deutsche Bank AG 0.05% Add +3.2% 556,579 $131.0M
Charles Schwab Investment Management Inc. 0.02% Add +5.5% 513,962 $120.9M
Amundi 0.04% Reduce -16.4% 496,301 $119.4M
TD Asset Management Inc 0.10% Add +3.2% 504,038 $118.6M
Loomis Sayles & Co. L P 0.15% Reduce -4.2% 503,045 $118.4M
Qube Research & Technologies Ltd 0.19% Add +218.9% 485,260 $114.2M
Bank of New York Mellon Corp 0.02% Add +1.0% 479,203 $112.8M
Nuveen Asset Management, LLC 0.03% Add +1.8% 448,881 $105.6M
Pictet Asset Management Holding SA 0.11% Reduce -35.2% 430,612 $101.3M
Bank of America Corp. 0.01% Reduce -24.0% 418,552 $98.5M
Orbimed Advisors LLC 2.03% Add +66.0% 415,600 $97.8M
Franklin Resources Inc. 0.03% Add +8.1% 414,139 $97.5M
Marshall Wace, LLP 0.11% Add +496.6% 378,649 $89.1M
Gilder Gagnon Howe & Co. LLC 0.93% Reduce -4.8% 365,463 $86.0M
D. E. Shaw & Co. 0.10% Add +9.3% 363,085 $85.4M
Swiss National Bank 0.06% Reduce -3.4% 362,600 $85.3M
Dimensional Fund Advisors LP 0.02% Add +10.7% 333,661 $78.5M
Millennium Management 0.07% Add +32.9% 333,442 $78.5M
First Trust Advisors LP 0.07% Add +14.8% 327,782 $77.1M
Royal Bank of Canada 0.02% Reduce -24.5% 310,187 $73.0M
Polar Capital Holdings Plc 0.41% No change 310,000 $72.9M
Goldman Sachs Group Inc. 0.01% Reduce -13.9% 306,455 $72.1M
UBS Group AG 0.02% Add +86.3% 289,966 $68.2M
Sumitomo Mitsui Trust Group, Inc. 0.05% Add +3.0% 286,703 $67.5M
Candriam S.C.A. 0.39% Reduce -19.7% 282,407 $66.5M
Royal London Asset Management Ltd. 0.16% Add +0.6% 281,509 $66.2M
Corient Private Wealth LP 0.11% Add +0.0% 278,566 $65.5M
Raymond James Financial Inc. 0.02% — 277,486 $65.3M
Wells Fargo & Company 0.02% Add +3.9% 276,962 $65.2M
Sei Investments Co. 0.08% Add +11.8% 266,000 $62.6M
Jennison Associates LLC 0.04% New 259,913 $61.2M
Rock Springs Capital Management LP 2.30% Add +2.5% 256,200 $60.3M
Federated Hermes, Inc. 0.13% Add +47.8% 249,591 $58.7M
Eventide Asset Management, LLC 1.03% Add +7.2% 240,418 $56.6M
Westfield Capital Management Co. LP 0.22% New 216,126 $50.9M
Janus Henderson Group PLC 0.03% Reduce -4.2% 210,080 $49.4M
CIBC Private Wealth Group LLC 0.09% Reduce -2.5% 203,368 $48.9M
California Public Employees Retirement System 0.03% Reduce -3.6% 204,132 $48.0M
California State Teachers Retirement System 0.05% Add +2.6% 196,362 $46.2M
Aberdeen Group plc 0.08% Reduce -4.6% 190,841 $45.2M
Rhumbline Advisers 0.04% Reduce -1.0% 179,578 $42.3M
Canada Pension Plan Investment Board 0.04% Reduce -49.5% 174,021 $40.9M
Jane Street Group, LLC 0.06% Add +17.9% 160,637 $37.8M
National Pension Service 0.04% Reduce -18.8% 159,511 $37.5M
Worldquant Millennium Advisors LLC 0.23% Add +156.7% 150,191 $35.3M
Deerfield Management Company, L.P. 0.73% Add +0.1% 145,191 $34.2M
Palo Alto Investors LP 5.13% No change 140,681 $33.1M
Casdin Capital, LLC 2.20% Reduce -17.6% 140,000 $32.9M
ANTIPODES PARTNERS Ltd 1.09% Reduce -4.0% 133,759 $31.5M
Ameriprise Financial Inc. 0.01% Reduce -7.1% 128,073 $30.1M
Squarepoint Ops LLC 0.08% Add +199.1% 127,697 $30.0M
Schonfeld Strategic Advisors LLC 0.19% Add +355.7% 127,000 $29.9M
Skandinaviska Enskilda Banken AB (publ) 0.13% Reduce -16.4% 125,491 $29.6M
State Board of Administration of Florida Retirement System 0.06% Reduce -3.2% 125,240 $29.5M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.06% — 124,360 $29.3M
Mitsubishi UFJ Trust & Banking Corp 0.06% Reduce -3.0% 116,686 $27.5M
HighTower Advisors, LLC 0.04% Reduce -0.3% 115,380 $27.2M
Capital International Sarl 0.63% Reduce -14.8% 115,142 $27.1M
DekaBank Deutsche Girozentrale 0.05% No change 113,193 $26.5M
Sofinnova Investments, Inc. 1.90% New 110,157 $25.9M
Neuberger Berman Group LLC 0.02% Add +3.3% 109,708 $25.8M
Manufacturers Life Insurance Company, The 0.02% Reduce -43.0% 109,102 $25.7M
Allianz Asset Management GmbH 0.04% Add +306.1% 108,871 $25.6M
Two Sigma Investments, LP 0.06% Add +459.4% 107,117 $25.2M
Capital International, Inc. 0.29% Reduce -16.1% 105,085 $24.7M
Frontier Capital Management Co. LLC 0.23% Reduce -5.9% 104,718 $24.6M
Barclays PLC 0.01% Reduce -1.3% 103,847 $24.4M
Robeco Institutional Asset Management B.V. 0.04% Add +35.9% 99,994 $23.5M
AXA S.A. 0.07% Reduce -14.3% 95,306 $22.4M
Voya Investment Management LLC 0.03% Reduce -12.5% 95,086 $22.4M
Los Angeles Capital Management LLC 0.09% Reduce -30.8% 94,822 $22.3M
Mitsubishi UFJ Asset Management Co., Ltd. 0.02% Add +11.0% 94,698 $22.2M
Korea Investment CORP 0.05% Reduce -13.2% 93,603 $22.0M
Adage Capital Partners Gp, L.L.C. 0.04% Reduce -19.8% 93,056 $21.9M

"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.

Show all 594 holders