Alnylam PharmaceuticalsALNY
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 594 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 26 from Q3 2024. 62 opened new positions and 61 sold out. The largest holders were Capital World Investors ($3.9B), FMR LLC ($3.2B) and Vanguard Group Inc. ($3.0B). 6 famous investors held it, including Cliff Asness (0.2% of AQR Capital Management's portfolio), David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.1% of Millennium Management's portfolio).
- Company
- Alnylam Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 02043Q107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 62 | $218.7M |
| Exits | 61 | $173.1M |
All 13F filers, Q3 2024 → Q4 2024: 8,045,977 shares bought and 8,840,820 shares sold, net −794,843 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 594 holders
| Capital World Investors | 0.59% | Add +0.6% | 16,600,525 | $3.9B |
| FMR LLC | 0.19% | Reduce -8.1% | 13,485,903 | $3.2B |
| Vanguard Group Inc. | 0.05% | Add +0.8% | 12,733,399 | $3.0B |
| BlackRock, Inc. | 0.05% | Add +1.8% | 9,885,257 | $2.3B |
| Capital Research Global Investors | 0.34% | Add +32.9% | 6,968,513 | $1.6B |
| Regeneron Pharmaceuticals, Inc. | 95.54% | — | 4,444,445 | $1.0B |
| T. Rowe Price Investment Management, Inc. | 0.64% | Add +39.7% | 4,384,449 | $1.0B |
| Wellington Management Group LLP | 0.18% | Reduce -15.3% | 4,196,623 | $987.5M |
| Baillie Gifford & Co. | 0.73% | Reduce -17.3% | 4,040,259 | $950.7M |
| Dodge & Cox | 0.49% | Reduce -2.3% | 3,540,262 | $833.1M |
| State Street Corp. | 0.03% | Reduce -1.3% | 3,422,877 | $805.5M |
| T. Rowe Price Associates Inc. | 0.09% | Reduce -3.8% | 3,319,385 | $781.1M |
| Norges Bank | 0.08% | Add +3.4% | 2,456,082 | $577.9M |
| JPMorgan Chase & Co. | 0.04% | Add +4.0% | 2,250,060 | $529.5M |
| Geode Capital Management, LLC | 0.04% | Add +2.8% | 2,206,800 | $518.4M |
| American Century Companies Inc. | 0.22% | Add +0.7% | 1,604,024 | $377.4M |
| Orbis Allan Gray Ltd | 1.86% | Add +16.1% | 1,472,802 | $346.6M |
| Capital International Investors | 0.06% | Reduce -64.3% | 1,418,602 | $333.8M |
| Winslow Capital Management, LLC | 0.85% | Add +6.1% | 1,020,567 | $240.1M |
| Northern Trust Corp. | 0.03% | Add +19.6% | 878,860 | $206.8M |
| Legal & General Group Plc | 0.05% | Add +4.7% | 828,917 | $195.1M |
| AQR Capital Management | 0.25% | Add +60.9% | 813,356 | $191.4M |
| Bellevue Group AG | 3.49% | Reduce -4.8% | 770,268 | $181.3M |
| Morgan Stanley | 0.01% | Add +17.6% | 727,224 | $171.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.04% | Add +0.6% | 710,598 | $167.2M |
| Invesco Ltd. | 0.02% | Reduce -19.7% | 558,490 | $131.4M |
| Deutsche Bank AG | 0.05% | Add +3.2% | 556,579 | $131.0M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +5.5% | 513,962 | $120.9M |
| Amundi | 0.04% | Reduce -16.4% | 496,301 | $119.4M |
| TD Asset Management Inc | 0.10% | Add +3.2% | 504,038 | $118.6M |
| Loomis Sayles & Co. L P | 0.15% | Reduce -4.2% | 503,045 | $118.4M |
| Qube Research & Technologies Ltd | 0.19% | Add +218.9% | 485,260 | $114.2M |
| Bank of New York Mellon Corp | 0.02% | Add +1.0% | 479,203 | $112.8M |
| Nuveen Asset Management, LLC | 0.03% | Add +1.8% | 448,881 | $105.6M |
| Pictet Asset Management Holding SA | 0.11% | Reduce -35.2% | 430,612 | $101.3M |
| Bank of America Corp. | 0.01% | Reduce -24.0% | 418,552 | $98.5M |
| Orbimed Advisors LLC | 2.03% | Add +66.0% | 415,600 | $97.8M |
| Franklin Resources Inc. | 0.03% | Add +8.1% | 414,139 | $97.5M |
| Marshall Wace, LLP | 0.11% | Add +496.6% | 378,649 | $89.1M |
| Gilder Gagnon Howe & Co. LLC | 0.93% | Reduce -4.8% | 365,463 | $86.0M |
| D. E. Shaw & Co. | 0.10% | Add +9.3% | 363,085 | $85.4M |
| Swiss National Bank | 0.06% | Reduce -3.4% | 362,600 | $85.3M |
| Dimensional Fund Advisors LP | 0.02% | Add +10.7% | 333,661 | $78.5M |
| Millennium Management | 0.07% | Add +32.9% | 333,442 | $78.5M |
| First Trust Advisors LP | 0.07% | Add +14.8% | 327,782 | $77.1M |
| Royal Bank of Canada | 0.02% | Reduce -24.5% | 310,187 | $73.0M |
| Polar Capital Holdings Plc | 0.41% | No change | 310,000 | $72.9M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -13.9% | 306,455 | $72.1M |
| UBS Group AG | 0.02% | Add +86.3% | 289,966 | $68.2M |
| Sumitomo Mitsui Trust Group, Inc. | 0.05% | Add +3.0% | 286,703 | $67.5M |
| Candriam S.C.A. | 0.39% | Reduce -19.7% | 282,407 | $66.5M |
| Royal London Asset Management Ltd. | 0.16% | Add +0.6% | 281,509 | $66.2M |
| Corient Private Wealth LP | 0.11% | Add +0.0% | 278,566 | $65.5M |
| Raymond James Financial Inc. | 0.02% | — | 277,486 | $65.3M |
| Wells Fargo & Company | 0.02% | Add +3.9% | 276,962 | $65.2M |
| Sei Investments Co. | 0.08% | Add +11.8% | 266,000 | $62.6M |
| Jennison Associates LLC | 0.04% | New | 259,913 | $61.2M |
| Rock Springs Capital Management LP | 2.30% | Add +2.5% | 256,200 | $60.3M |
| Federated Hermes, Inc. | 0.13% | Add +47.8% | 249,591 | $58.7M |
| Eventide Asset Management, LLC | 1.03% | Add +7.2% | 240,418 | $56.6M |
| Westfield Capital Management Co. LP | 0.22% | New | 216,126 | $50.9M |
| Janus Henderson Group PLC | 0.03% | Reduce -4.2% | 210,080 | $49.4M |
| CIBC Private Wealth Group LLC | 0.09% | Reduce -2.5% | 203,368 | $48.9M |
| California Public Employees Retirement System | 0.03% | Reduce -3.6% | 204,132 | $48.0M |
| California State Teachers Retirement System | 0.05% | Add +2.6% | 196,362 | $46.2M |
| Aberdeen Group plc | 0.08% | Reduce -4.6% | 190,841 | $45.2M |
| Rhumbline Advisers | 0.04% | Reduce -1.0% | 179,578 | $42.3M |
| Canada Pension Plan Investment Board | 0.04% | Reduce -49.5% | 174,021 | $40.9M |
| Jane Street Group, LLC | 0.06% | Add +17.9% | 160,637 | $37.8M |
| National Pension Service | 0.04% | Reduce -18.8% | 159,511 | $37.5M |
| Worldquant Millennium Advisors LLC | 0.23% | Add +156.7% | 150,191 | $35.3M |
| Deerfield Management Company, L.P. | 0.73% | Add +0.1% | 145,191 | $34.2M |
| Palo Alto Investors LP | 5.13% | No change | 140,681 | $33.1M |
| Casdin Capital, LLC | 2.20% | Reduce -17.6% | 140,000 | $32.9M |
| ANTIPODES PARTNERS Ltd | 1.09% | Reduce -4.0% | 133,759 | $31.5M |
| Ameriprise Financial Inc. | 0.01% | Reduce -7.1% | 128,073 | $30.1M |
| Squarepoint Ops LLC | 0.08% | Add +199.1% | 127,697 | $30.0M |
| Schonfeld Strategic Advisors LLC | 0.19% | Add +355.7% | 127,000 | $29.9M |
| Skandinaviska Enskilda Banken AB (publ) | 0.13% | Reduce -16.4% | 125,491 | $29.6M |
| State Board of Administration of Florida Retirement System | 0.06% | Reduce -3.2% | 125,240 | $29.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.06% | — | 124,360 | $29.3M |
| Mitsubishi UFJ Trust & Banking Corp | 0.06% | Reduce -3.0% | 116,686 | $27.5M |
| HighTower Advisors, LLC | 0.04% | Reduce -0.3% | 115,380 | $27.2M |
| Capital International Sarl | 0.63% | Reduce -14.8% | 115,142 | $27.1M |
| DekaBank Deutsche Girozentrale | 0.05% | No change | 113,193 | $26.5M |
| Sofinnova Investments, Inc. | 1.90% | New | 110,157 | $25.9M |
| Neuberger Berman Group LLC | 0.02% | Add +3.3% | 109,708 | $25.8M |
| Manufacturers Life Insurance Company, The | 0.02% | Reduce -43.0% | 109,102 | $25.7M |
| Allianz Asset Management GmbH | 0.04% | Add +306.1% | 108,871 | $25.6M |
| Two Sigma Investments, LP | 0.06% | Add +459.4% | 107,117 | $25.2M |
| Capital International, Inc. | 0.29% | Reduce -16.1% | 105,085 | $24.7M |
| Frontier Capital Management Co. LLC | 0.23% | Reduce -5.9% | 104,718 | $24.6M |
| Barclays PLC | 0.01% | Reduce -1.3% | 103,847 | $24.4M |
| Robeco Institutional Asset Management B.V. | 0.04% | Add +35.9% | 99,994 | $23.5M |
| AXA S.A. | 0.07% | Reduce -14.3% | 95,306 | $22.4M |
| Voya Investment Management LLC | 0.03% | Reduce -12.5% | 95,086 | $22.4M |
| Los Angeles Capital Management LLC | 0.09% | Reduce -30.8% | 94,822 | $22.3M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.02% | Add +11.0% | 94,698 | $22.2M |
| Korea Investment CORP | 0.05% | Reduce -13.2% | 93,603 | $22.0M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Reduce -19.8% | 93,056 | $21.9M |
"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.