Alnylam PharmaceuticalsALNY
13F holders, Q2 2025 (June 30)654holders +28
90new positions
62sold out
6famous investors
$326.06avg. 13F price*
At the end of Q2 2025, 654 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, up 28 from Q1 2025. 90 opened new positions and 62 sold out. The largest holders were Capital World Investors ($5.5B), FMR LLC ($5.2B) and Vanguard Group Inc. ($4.3B). 6 famous investors held it, including Ken Griffin (0.2% of Citadel Advisors's portfolio), Steve Cohen (0.2% of Point72 Asset Management's portfolio) and Cliff Asness (0.1% of AQR Capital Management's portfolio).
- Company
- Alnylam Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 02043Q107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 90 | $384.4M |
| Exits | 62 | $273.5M |
All 13F filers, Q1 2025 → Q2 2025: 9,205,253 shares bought and 6,502,589 shares sold, net +2,702,664 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 654 holders
| Capital World Investors | 0.80% | Add +0.3% | 16,805,007 | $5.5B |
| FMR LLC | 0.29% | Add +3.2% | 15,806,521 | $5.2B |
| Vanguard Group Inc. | 0.07% | Add +1.8% | 13,297,139 | $4.3B |
| BlackRock, Inc. | 0.06% | Add +4.4% | 9,980,163 | $3.3B |
| Capital Research Global Investors | 0.47% | Add +0.5% | 7,191,656 | $2.3B |
| Regeneron Pharmaceuticals, Inc. | 97.59% | No change | 4,444,445 | $1.4B |
| T. Rowe Price Investment Management, Inc. | 0.88% | Reduce -3.1% | 4,281,279 | $1.4B |
| Dodge & Cox | 0.59% | Reduce -4.6% | 3,197,096 | $1.0B |
| State Street Corp. | 0.04% | Reduce -5.8% | 3,173,105 | $1.0B |
| T. Rowe Price Associates Inc. | 0.12% | Reduce -10.3% | 3,145,006 | $1.0B |
| Baillie Gifford & Co. | 0.74% | Reduce -17.1% | 3,031,891 | $988.7M |
| Geode Capital Management, LLC | 0.05% | Add +3.3% | 2,398,770 | $779.9M |
| Orbis Allan Gray Ltd | 3.36% | Add +29.8% | 2,121,412 | $691.8M |
| Wellington Management Group LLP | 0.12% | Reduce -20.5% | 2,075,752 | $676.9M |
| JPMorgan Chase & Co. | 0.05% | Reduce -7.1% | 2,062,008 | $672.4M |
| Norges Bank | 0.08% | Reduce -4.8% | 2,032,680 | $662.8M |
| American Century Companies Inc. | 0.32% | Add +1.9% | 1,793,846 | $585.0M |
| Invesco Ltd. | 0.07% | Add +46.8% | 1,341,694 | $437.5M |
| Bank of America Corp. | 0.03% | Add +18.1% | 1,257,328 | $410.0M |
| Winslow Capital Management, LLC | 1.28% | Reduce -0.8% | 1,177,439 | $384.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.06% | Add +30.2% | 958,336 | $312.5M |
| Legal & General Group Plc | 0.07% | Reduce -0.9% | 872,771 | $284.6M |
| Northern Trust Corp. | 0.04% | Reduce -3.8% | 831,777 | $271.2M |
| Nuveen, LLC | 0.07% | Reduce -12.3% | 774,969 | $252.7M |
| Morgan Stanley | 0.02% | Add +20.1% | 770,968 | $251.4M |
| Bellevue Group AG | 4.86% | Reduce -11.9% | 676,367 | $220.6M |
| Deutsche Bank AG | 0.08% | Add +12.5% | 649,284 | $211.7M |
| Woodline Partners LP | 1.07% | Add +298.3% | 623,115 | $203.2M |
| Franklin Resources Inc. | 0.05% | Add +31.2% | 601,331 | $196.1M |
| Citadel Advisors | 0.17% | Add +14092.6% | 601,199 | $196.0M |
| Macquarie Group Ltd. | 0.24% | Add +726.7% | 600,111 | $195.7M |
| Holocene Advisors, LP | 0.48% | New | 596,816 | $194.6M |
| Charles Schwab Investment Management Inc. | 0.03% | Add +4.6% | 571,747 | $186.4M |
| Clearbridge Investments, LLC | 0.15% | Add +7063.4% | 557,099 | $181.7M |
| Goldman Sachs Group Inc. | 0.03% | Add +28.8% | 545,316 | $177.8M |
| UBS Group AG | 0.04% | Add +95.0% | 543,486 | $177.2M |
| Loomis Sayles & Co. L P | 0.20% | Reduce -2.0% | 487,328 | $158.9M |
| Pictet Asset Management Holding SA | 0.15% | Reduce -3.4% | 464,606 | $151.2M |
| TD Asset Management Inc | 0.12% | Reduce -9.3% | 441,177 | $143.9M |
| Royal Bank of Canada | 0.03% | Add +27.8% | 430,835 | $140.5M |
| Bank of New York Mellon Corp | 0.03% | Reduce -9.5% | 429,769 | $140.1M |
| Amundi | 0.05% | Reduce -13.4% | 394,179 | $130.0M |
| Swiss National Bank | 0.08% | Add +8.1% | 393,800 | $128.4M |
| Jennison Associates LLC | 0.07% | Add +13.2% | 350,070 | $114.2M |
| Two Sigma Investments, LP | 0.21% | Add +73.9% | 343,305 | $111.9M |
| Orbimed Advisors LLC | 2.80% | Reduce -1.2% | 341,900 | $111.5M |
| Gilder Gagnon Howe & Co. LLC | 1.17% | Reduce -2.5% | 337,088 | $109.9M |
| Federated Hermes, Inc. | 0.20% | Add +22.6% | 323,842 | $105.6M |
| Wells Fargo & Company | 0.02% | Add +7.3% | 321,824 | $104.9M |
| Sei Investments Co. | 0.12% | Add +11.3% | 308,619 | $100.6M |
| Allspring Global Investments Holdings, LLC | 0.17% | Add +15.2% | 312,216 | $100.6M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -1.4% | 305,563 | $99.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.06% | Add +0.7% | 293,542 | $95.7M |
| Raymond James Financial Inc. | 0.03% | Add +0.6% | 270,450 | $88.2M |
| Two Sigma Advisers, LP | 0.18% | Reduce -3.5% | 266,100 | $86.8M |
| Royal London Asset Management Ltd. | 0.19% | Reduce -9.7% | 259,071 | $84.5M |
| First Trust Advisors LP | 0.07% | Add +39.5% | 251,817 | $82.1M |
| Citigroup Inc. | 0.06% | Add +27.5% | 248,238 | $80.9M |
| Marshall Wace, LLP | 0.09% | Reduce -11.3% | 238,573 | $77.8M |
| Candriam S.C.A. | 0.45% | Reduce -4.7% | 238,084 | $77.6M |
| Polar Capital Holdings Plc | 0.41% | Reduce -15.2% | 237,500 | $77.4M |
| 1832 Asset Management L.P. | 0.13% | Add +55.0% | 223,345 | $72.8M |
| CIBC Private Wealth Group LLC | 0.13% | Add +6.2% | 218,329 | $71.2M |
| Aberdeen Group plc | 0.12% | Add +1.5% | 218,624 | $70.4M |
| California Public Employees Retirement System | 0.04% | Add +5.0% | 211,581 | $69.0M |
| Voya Investment Management LLC | 0.08% | Add +131.6% | 211,045 | $68.8M |
| Susquehanna International Group, LLP | 0.10% | Add +195.6% | 208,262 | $67.9M |
| Allianz Asset Management GmbH | 0.09% | Reduce -5.7% | 205,993 | $67.2M |
| Point72 Asset Management | 0.16% | Reduce -33.0% | 201,396 | $65.7M |
| Rhumbline Advisers | 0.06% | Add +10.5% | 200,485 | $65.4M |
| California State Teachers Retirement System | 0.07% | Add +0.9% | 199,316 | $65.0M |
| Ameriprise Financial Inc. | 0.02% | Add +77.4% | 193,649 | $63.1M |
| KBC Group NV | 0.17% | Add +902.2% | 193,550 | $63.1M |
| AQR Capital Management | 0.05% | Reduce -77.3% | 188,249 | $61.3M |
| Westfield Capital Management Co. LP | 0.26% | Reduce -2.7% | 186,905 | $60.9M |
| National Pension Service | 0.05% | Add +0.8% | 175,046 | $57.1M |
| SCS Capital Management LLC | 0.62% | Reduce -0.2% | 170,662 | $55.7M |
| Arrowstreet Capital, Limited Partnership | 0.04% | Add +4085.0% | 169,700 | $55.3M |
| Victory Capital Management Inc. | 0.03% | Add +315.1% | 156,294 | $51.0M |
| Handelsbanken Fonder AB | 0.18% | Add +33.1% | 155,362 | $50.7M |
| Janus Henderson Group PLC | 0.02% | Reduce -17.2% | 150,421 | $49.0M |
| FIL Ltd | 0.04% | Add +25.5% | 147,937 | $48.2M |
| Deerfield Management Company, L.P. | 0.96% | No change | 145,000 | $47.3M |
| BNP Paribas Financial Markets | 0.03% | Add +202.1% | 128,634 | $41.9M |
| Capital International Sarl | 0.80% | Add +5.9% | 128,286 | $41.8M |
| State Board of Administration of Florida Retirement System | 0.07% | Add +1.4% | 127,050 | $41.4M |
| Eventide Asset Management, LLC | 0.72% | Reduce -24.4% | 125,902 | $41.1M |
| ANTIPODES PARTNERS Ltd | 1.24% | Reduce -23.0% | 122,804 | $40.0M |
| Worldquant Millennium Advisors LLC | 0.19% | Reduce -38.6% | 117,373 | $38.3M |
| Balyasny Asset Management L.P. | 0.09% | Add +778.9% | 115,275 | $37.6M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.07% | Reduce -2.9% | 114,366 | $37.3M |
| DekaBank Deutsche Girozentrale | 0.07% | Add +0.1% | 113,193 | $36.5M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.03% | Add +5.6% | 111,785 | $36.5M |
| Korea Investment CORP | 0.08% | Add +4.8% | 110,855 | $36.1M |
| HighTower Advisors, LLC | 0.04% | Reduce -4.0% | 109,265 | $35.6M |
| D. E. Shaw & Co. | 0.04% | Reduce -62.6% | 108,276 | $35.3M |
| Soleus Capital Management, L.P. | 2.40% | New | 106,750 | $34.8M |
| Frontier Capital Management Co. LLC | 0.31% | Add +0.6% | 103,003 | $33.6M |
| Ensign Peak Advisors, Inc | 0.06% | Add +24.5% | 100,209 | $32.7M |
| Rock Springs Capital Management LP | 2.04% | Reduce -30.2% | 100,000 | $32.6M |
"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.