Alnylam PharmaceuticalsALNY
13F holders, Q1 2026 (March 31)793holders −59
92new positions
151sold out
7famous investors
$330.10avg. 13F price*
At the end of Q1 2026, 793 institutions reported holding Alnylam Pharmaceuticals Inc. (ALNY) in their 13F filings, down 59 from Q4 2025. 92 opened new positions and 151 sold out. The largest holders were FMR LLC ($4.8B), Capital World Investors ($3.6B) and BlackRock, Inc. ($3.5B). 7 famous investors held it, including David E. Shaw (0.3% of D. E. Shaw & Co.'s portfolio), Ray Dalio (0.2% of Bridgewater Associates's portfolio) and Cliff Asness (0.1% of AQR Capital Management's portfolio).
- Company
- Alnylam Pharmaceuticals Inc.
- Sector
- Health Care
- CUSIP
- 02043Q107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 92 | $191.0M |
| Exits | 151 | $932.1M |
All 13F filers, Q4 2025 → Q1 2026: 17,373,426 shares bought and 15,410,383 shares sold, net +1,963,043 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 793 holders
| FMR LLC | 0.25% | Reduce -8.3% | 14,579,166 | $4.8B |
| Capital World Investors | 0.49% | Reduce -33.7% | 10,802,348 | $3.6B |
| BlackRock, Inc. | 0.06% | Add +0.4% | 10,444,908 | $3.5B |
| Capital Research Global Investors | 0.49% | Add +39.7% | 9,471,181 | $3.1B |
| Vanguard Portfolio Management LLC | 0.11% | — | 6,491,280 | $2.1B |
| JPMorgan Chase & Co. | 0.14% | Add +34.0% | 6,323,752 | $2.0B |
| Vanguard Capital Management LLC | 0.05% | — | 5,946,706 | $2.0B |
| T. Rowe Price Investment Management, Inc. | 1.18% | Add +196.2% | 5,193,324 | $1.7B |
| Invesco Ltd. | 0.13% | Reduce -20.6% | 4,075,120 | $1.3B |
| State Street Corp. | 0.04% | Add +2.9% | 3,322,698 | $1.1B |
| Geode Capital Management, LLC | 0.06% | Add +0.4% | 2,660,385 | $884.6M |
| Baillie Gifford & Co. | 0.84% | Reduce -4.1% | 2,493,866 | $825.1M |
| Two Sigma Investments, LP | 0.57% | Add +223.4% | 1,992,577 | $659.3M |
| Wellington Management Group LLP | 0.12% | Add +18.9% | 1,935,925 | $640.5M |
| Dodge & Cox | 0.35% | Reduce -1.8% | 1,929,253 | $638.3M |
| American Century Companies Inc. | 0.31% | Add +21.4% | 1,802,363 | $596.3M |
| T. Rowe Price Associates Inc. | 0.05% | Reduce -15.9% | 1,432,748 | $474.1M |
| Clearbridge Investments, LLC | 0.39% | Add +127.1% | 1,356,036 | $448.7M |
| Orbis Allan Gray Ltd | 1.86% | Reduce -17.5% | 1,334,825 | $441.7M |
| Marshall Wace, LLP | 0.39% | Add +99.9% | 1,099,318 | $363.7M |
| D. E. Shaw & Co. | 0.30% | Add +138.3% | 1,059,062 | $350.4M |
| Morgan Stanley | 0.02% | Add +3.4% | 1,002,681 | $331.8M |
| Bank of America Corp. | 0.02% | Add +41.1% | 966,912 | $319.9M |
| Legal & General Group Plc | 0.07% | Reduce -2.8% | 934,881 | $309.3M |
| AQR Capital Management | 0.14% | Reduce -0.8% | 913,104 | $297.9M |
| Northern Trust Corp. | 0.04% | Add +0.0% | 858,120 | $283.9M |
| Vanguard Fiduciary Trust Co. | 0.07% | — | 840,888 | $278.2M |
| Qube Research & Technologies Ltd | 0.39% | Add +8.2% | 838,187 | $277.3M |
| Royal Bank of Canada | 0.05% | Add +33.8% | 791,515 | $261.9M |
| Deutsche Bank AG | 0.08% | Add +7.0% | 761,464 | $251.9M |
| Amundi | 0.07% | Add +22.8% | 747,544 | $247.3M |
| Federated Hermes, Inc. | 0.37% | Add +9.5% | 687,816 | $227.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.05% | Add +3.9% | 677,519 | $224.2M |
| Charles Schwab Investment Management Inc. | 0.03% | Add +3.9% | 673,356 | $222.8M |
| Manufacturers Life Insurance Company, The | 0.19% | Add +944.5% | 662,365 | $219.2M |
| Loomis Sayles & Co. L P | 0.23% | Add +4.8% | 512,097 | $169.4M |
| Massachusetts Financial Services Co. | 0.06% | Add +0.1% | 496,004 | $164.1M |
| Bank of New York Mellon Corp | 0.03% | Reduce -2.6% | 491,200 | $162.5M |
| Franklin Resources Inc. | 0.04% | Reduce -40.3% | 470,390 | $155.6M |
| Goldman Sachs Group Inc. | 0.02% | Add +25.1% | 469,388 | $155.3M |
| UBS Group AG | 0.03% | Reduce -44.4% | 458,870 | $151.8M |
| Millennium Management | 0.12% | Add +493.8% | 447,887 | $148.2M |
| Squarepoint Ops LLC | 0.30% | Add +21.6% | 426,723 | $141.2M |
| Raymond James Financial Inc. | 0.04% | Add +4.7% | 406,956 | $130.0M |
| Swiss National Bank | 0.07% | Add +7.9% | 387,720 | $128.3M |
| Dimensional Fund Advisors LP | 0.03% | Add +27.3% | 384,205 | $127.1M |
| First Trust Advisors LP | 0.09% | Add +48.9% | 382,701 | $126.6M |
| Wells Fargo & Company | 0.02% | Add +33.0% | 342,763 | $113.4M |
| Nuveen, LLC | 0.03% | Reduce -43.0% | 322,232 | $106.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.07% | Reduce -4.1% | 314,417 | $104.0M |
| Congress Asset Management Co. | 0.68% | Add +6.1% | 285,739 | $94.5M |
| TD Asset Management Inc | 0.08% | Add +4.7% | 281,848 | $93.3M |
| BNP Paribas Financial Markets | 0.06% | Reduce -27.9% | 280,965 | $93.0M |
| Gilder Gagnon Howe & Co. LLC | 1.11% | Reduce -12.3% | 280,092 | $92.7M |
| Allspring Global Investments Holdings, LLC | 0.16% | Add +1.1% | 281,793 | $92.6M |
| Pinebridge Investments LLC | 0.76% | Add +170.9% | 271,419 | $89.8M |
| Citigroup Inc. | 0.06% | Add +52.6% | 263,375 | $87.1M |
| Nomura Asset Management International Inc. | 0.15% | Reduce -16.9% | 258,905 | $85.7M |
| Polar Capital Holdings Plc | 0.37% | Add +7.1% | 257,674 | $85.3M |
| Westfield Capital Management Co. LP | 0.34% | Add +162.8% | 245,539 | $81.2M |
| Woodline Partners LP | 0.31% | Add +13764.9% | 243,883 | $80.7M |
| Ameriprise Financial Inc. | 0.02% | Add +32.5% | 239,941 | $79.4M |
| Bellevue Group AG | 1.85% | Reduce -47.4% | 234,543 | $77.6M |
| Pictet Asset Management Holding SA | 0.08% | Reduce -24.7% | 237,920 | $77.5M |
| Man Group plc | 0.16% | Add +61.1% | 232,369 | $76.9M |
| California Public Employees Retirement System | 0.05% | Reduce -3.8% | 227,997 | $75.4M |
| Candriam S.C.A. | 0.39% | No change | 224,330 | $74.2M |
| Barclays PLC | 0.03% | Reduce -0.9% | 220,623 | $73.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.06% | — | 219,235 | $72.5M |
| Royal London Asset Management Ltd. | 0.15% | Reduce -15.0% | 215,075 | $71.2M |
| Jacobs Levy Equity Management, Inc. | 0.30% | Reduce -47.1% | 212,204 | $70.2M |
| Canada Pension Plan Investment Board | 0.04% | Reduce -19.2% | 208,938 | $69.1M |
| Korea Investment CORP | 0.14% | Add +5.6% | 200,321 | $66.3M |
| California State Teachers Retirement System | 0.07% | Reduce -2.5% | 196,863 | $65.1M |
| Victory Capital Management Inc. | 0.04% | Reduce -11.3% | 195,937 | $64.8M |
| Rhumbline Advisers | 0.06% | Add +0.0% | 195,277 | $64.6M |
| Voloridge Investment Management, LLC | 0.25% | Add +17.8% | 189,217 | $62.6M |
| National Pension Service | 0.05% | Add +9.3% | 183,789 | $60.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.07% | Add +64.2% | 180,012 | $59.6M |
| Life Cycle Investment Partners Ltd | 0.37% | Add +101.6% | 177,541 | $58.7M |
| Susquehanna International Group, LLP | 0.07% | Reduce -9.2% | 174,268 | $57.7M |
| ProShare Advisors LLC | 0.09% | Reduce -17.6% | 174,013 | $57.6M |
| Envestnet Asset Management Inc. | 0.02% | Add +42.5% | 171,797 | $56.8M |
| CIBC Bancorp USA Inc. | 0.08% | — | 169,031 | $55.9M |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.03% | Add +9.7% | 152,197 | $50.4M |
| SCS Capital Management LLC | 0.52% | Reduce -0.0% | 149,547 | $49.5M |
| Voya Investment Management LLC | 0.06% | Reduce -25.2% | 148,488 | $49.1M |
| Janus Henderson Group PLC | 0.02% | Add +7.8% | 147,089 | $48.7M |
| Russell Investments Group, Ltd. | 0.05% | Reduce -11.0% | 147,533 | $48.5M |
| ANTIPODES PARTNERS Ltd | 0.93% | Add +203.4% | 145,310 | $48.1M |
| Capital Fund Management S.A. | 0.41% | Add +569.1% | 140,109 | $46.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.08% | Add +12.1% | 139,708 | $46.1M |
| Aberdeen Group plc | 0.07% | Add +4.1% | 138,331 | $45.8M |
| Handelsbanken Fonder AB | 0.15% | Add +0.2% | 136,462 | $45.2M |
| Brown Advisory Inc. | 0.07% | Add +438.9% | 133,953 | $44.3M |
| Soleus Capital Management, L.P. | 1.76% | Add +88.1% | 131,650 | $43.6M |
| Assenagon Asset Management S.A. | 0.07% | Add +403.7% | 128,896 | $42.6M |
| HRT Financial LP | 0.11% | New | 128,633 | $42.6M |
| Robeco Institutional Asset Management B.V. | 0.06% | Reduce -12.6% | 126,463 | $41.8M |
| Orbimed Advisors LLC | 0.89% | Reduce -58.8% | 119,000 | $39.4M |
"% of holder's portfolio" is ALNY's weight in each manager's 13F, not the share of Alnylam Pharmaceuticals Inc. the manager owns.