AnnexonANNX
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 217 institutions reported holding Annexon Inc. (ANNX) in their 13F filings, up 49 from Q4 2025. 58 opened new positions and 15 sold out. The largest holders were Redmile Group, LLC ($80.6M), BlackRock, Inc. ($60.6M) and FMR LLC ($58.9M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Annexon Inc.
- CUSIP
- 03589W102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 58 | $66.5M |
| Exits | 15 | $11.0M |
All 13F filers, Q4 2025 → Q1 2026: 35,779,460 shares bought and 17,473,755 shares sold, net +18,305,705 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 217 holders
| Redmile Group, LLC | 5.34% | Add +44.8% | 14,549,768 | $80.6M |
| BlackRock, Inc. | 0.00% | Add +22.1% | 10,938,509 | $60.6M |
| FMR LLC | 0.00% | Add +4.0% | 10,635,648 | $58.9M |
| BVF Inc. | 1.54% | Reduce -4.7% | 8,698,173 | $48.2M |
| State Street Corp. | 0.00% | Add +48.7% | 6,919,255 | $38.3M |
| Vanguard Capital Management LLC | 0.00% | — | 5,956,589 | $33.0M |
| Bain Capital Life Sciences Investors, LLC | 2.61% | Reduce -0.7% | 5,212,674 | $28.9M |
| Bellevue Group AG | 0.68% | No change | 5,157,290 | $28.6M |
| Mak Capital One LLC | 4.33% | Add +59.7% | 4,724,043 | $26.2M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Reduce -21.8% | 4,300,000 | $23.8M |
| Bank of America Corp. | 0.00% | Add +165.3% | 4,259,995 | $23.6M |
| Nuveen, LLC | 0.01% | Add +45.7% | 4,246,330 | $23.5M |
| Siren, L.L.C. | 0.61% | New | 3,958,646 | $21.9M |
| Balyasny Asset Management L.P. | 0.04% | Add +17.8% | 3,886,909 | $21.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -20.7% | 3,449,121 | $19.1M |
| Geode Capital Management, LLC | 0.00% | Add +16.4% | 3,377,823 | $18.7M |
| Qube Research & Technologies Ltd | 0.02% | Add +30.8% | 3,114,314 | $17.3M |
| Palo Alto Investors LP | 2.50% | Add +23.6% | 2,948,090 | $16.3M |
| Morgan Stanley | 0.00% | Reduce -4.2% | 2,735,970 | $15.2M |
| Great Point Partners LLC | 3.39% | New | 2,500,000 | $13.8M |
| Woodline Partners LP | 0.05% | Reduce -41.6% | 2,337,137 | $12.9M |
| Opaleye Management Inc. | 1.70% | Reduce -10.3% | 2,331,761 | $12.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +21.7% | 2,152,880 | $11.9M |
| Point72 Asset Management | 0.02% | Add +404.3% | 1,871,795 | $10.4M |
| Vanguard Portfolio Management LLC | 0.00% | — | 1,483,090 | $8.2M |
| Y-Intercept (Hong Kong) Ltd | 0.14% | New | 1,319,913 | $7.3M |
| Tetragon Partners GP Ltd | 1.41% | Reduce -36.4% | 1,292,455 | $7.2M |
| UBS Group AG | 0.00% | Add +230.4% | 1,245,941 | $6.9M |
| Millennium Management | 0.01% | Reduce -56.3% | 1,238,678 | $6.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.3% | 1,102,445 | $6.1M |
| Northern Trust Corp. | 0.00% | Add +37.2% | 1,086,902 | $6.0M |
| Dimensional Fund Advisors LP | 0.00% | Add +28.6% | 924,078 | $5.1M |
| Kennedy Capital Management LLC | 0.11% | Add +42.6% | 912,323 | $5.1M |
| Massachusetts Financial Services Co. | 0.00% | Reduce -0.0% | 903,368 | $5.0M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 888,552 | $4.9M |
| Marshall Wace, LLP | 0.01% | Add +65.3% | 861,475 | $4.8M |
| AQR Capital Management | 0.00% | Add +0.1% | 777,253 | $4.3M |
| Invesco Ltd. | 0.00% | Reduce -21.5% | 763,005 | $4.2M |
| Acadian Asset Management LLC | 0.01% | Reduce -12.0% | 758,232 | $4.2M |
| Russell Investments Group, Ltd. | 0.00% | Add +4.2% | 711,380 | $3.9M |
| D. E. Shaw & Co. | 0.00% | Reduce -32.8% | 702,799 | $3.9M |
| Wells Fargo & Company | 0.00% | Add +21.8% | 698,739 | $3.9M |
| Parkman Healthcare Partners LLC | 0.39% | Add +12.1% | 674,013 | $3.7M |
| Ensign Peak Advisors, Inc | 0.01% | New | 625,097 | $3.5M |
| Longaeva Partners L.P. | 0.17% | Reduce -80.0% | 620,401 | $3.4M |
| Citadel Advisors | 0.00% | Add +118.0% | 600,135 | $3.3M |
| Deerfield Management Company, L.P. | 0.05% | No change | 583,913 | $3.2M |
| Ikarian Capital, LLC | 0.46% | Add +152.0% | 580,244 | $3.2M |
| Sirios Capital Management L P | 0.39% | Reduce -19.0% | 575,063 | $3.2M |
| Deutsche Bank AG | 0.00% | Add +0.3% | 562,181 | $3.1M |
| Renaissance Technologies | 0.00% | Reduce -32.2% | 544,300 | $3.0M |
| Wellington Management Group LLP | 0.00% | Add +31.0% | 521,379 | $2.9M |
| Hennion & Walsh Asset Management, Inc. | 0.10% | Reduce -4.7% | 509,689 | $2.8M |
| Silverarc Capital Management, LLC | 0.32% | New | 496,461 | $2.8M |
| Board of Trustees of The Leland Stanford Junior University | 0.32% | No change | 482,550 | $2.7M |
| Two Sigma Investments, LP | 0.00% | Add +42.0% | 471,391 | $2.6M |
| Voloridge Investment Management, LLC | 0.01% | New | 462,068 | $2.6M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -3.7% | 428,720 | $2.4M |
| Mutual of America Capital Management LLC | 0.03% | Reduce -35.1% | 416,698 | $2.3M |
| Trexquant Investment LP | 0.02% | New | 403,657 | $2.2M |
| Bank of New York Mellon Corp | 0.00% | Add +9.2% | 395,019 | $2.2M |
| Susquehanna Portfolio Strategies, LLC | 0.03% | Add +1.0% | 360,319 | $2.0M |
| JPMorgan Chase & Co. | 0.00% | Add +502.8% | 323,894 | $1.6M |
| Cinctive Capital Management LP | 0.10% | Reduce -25.2% | 268,640 | $1.5M |
| BNP Paribas Financial Markets | 0.00% | Add +314.8% | 255,371 | $1.4M |
| Swiss National Bank | 0.00% | New | 236,000 | $1.3M |
| Rafferty Asset Management, LLC | 0.00% | Add +43.5% | 203,269 | $1.1M |
| Sei Investments Co. | 0.00% | Add +248.8% | 203,236 | $1.1M |
| Rosalind Advisors, Inc. | 0.45% | New | 200,000 | $1.1M |
| Ieq Capital, LLC | 0.01% | Add +7.0% | 195,764 | $1.1M |
| Ishara Investments LP | 0.97% | Reduce -76.8% | 174,250 | $965K |
| Engineers Gate Manager LP | 0.01% | New | 174,141 | $965K |
| J. Goldman & Co LP | 0.04% | Reduce -82.8% | 170,817 | $946K |
| Boothbay Fund Management, LLC | 0.02% | Add +159.3% | 166,164 | $921K |
| Rhumbline Advisers | 0.00% | Add +26.3% | 159,670 | $885K |
| Susquehanna International Group, LLP | 0.00% | Reduce -14.5% | 158,640 | $879K |
| Algert Global LLC | 0.01% | New | 154,840 | $858K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -78.2% | 148,941 | $825K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +3.6% | 134,786 | $747K |
| Diadema Partners LP | 0.30% | Reduce -62.0% | 132,916 | $736K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 130,647 | $724K |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -76.4% | 123,282 | $683K |
| DAFNA Capital Management LLC | 0.15% | Reduce -56.8% | 117,812 | $653K |
| Victory Capital Management Inc. | 0.00% | Add +682.9% | 115,527 | $640K |
| Man Group plc | 0.00% | New | 109,222 | $605K |
| Alliancebernstein L.P. | 0.00% | Reduce -15.4% | 119,050 | $598K |
| SCS Capital Management LLC | 0.01% | New | 99,000 | $548K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -29.0% | 97,800 | $542K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 92,707 | $514K |
| Profund Advisors LLC | 0.02% | Add +71.6% | 90,959 | $504K |
| J. Safra Sarasin Holding AG | 0.01% | Reduce -23.2% | 90,487 | $501K |
| DNB Asset Management AS | 0.00% | Reduce -25.1% | 88,617 | $491K |
| XTX Topco Ltd | 0.01% | Reduce -66.9% | 80,495 | $446K |
| Legal & General Group Plc | 0.00% | Add +760.1% | 80,046 | $443K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 79,486 | $440K |
| Captrust Financial Advisors | 0.00% | Add +150.7% | 79,173 | $439K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +39.3% | 76,257 | $414K |
| MetLife Investment Management, LLC | 0.00% | Add +85.5% | 72,444 | $401K |
| Polen Capital Management LLC | 0.00% | New | 70,152 | $389K |
| Squarepoint Ops LLC | 0.00% | New | 67,956 | $376K |
| Los Angeles Capital Management LLC | 0.00% | New | 62,073 | $344K |
| Janus Henderson Group PLC | 0.00% | New | 59,100 | $328K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -52.8% | 58,433 | $324K |
| Axq Capital, LP | 0.04% | Add +99.9% | 58,185 | $322K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +59.9% | 57,683 | $320K |
| STRS Ohio | 0.00% | New | 55,500 | $307K |
| ADAR1 Capital Management, LLC | 0.02% | Add +14.6% | 55,000 | $305K |
| Virtus Investment Advisers, LLC | 0.08% | Add +2.5% | 54,866 | $304K |
| DRW Securities, LLC | 0.02% | New | 54,484 | $302K |
| Vanguard Global Advisers, LLC | 0.00% | — | 54,054 | $299K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | New | 53,867 | $298K |
| Verdad Advisers, LP | 0.33% | New | 53,277 | $295K |
| Mariner, LLC | 0.00% | Add +69.9% | 53,242 | $295K |
| EntryPoint Capital, LLC | 0.08% | Add +20.2% | 51,421 | $285K |
| BIT Capital GmbH | 0.02% | New | 50,000 | $277K |
| State of Wisconsin Investment Board | 0.00% | New | 49,746 | $276K |
| Jane Street Group, LLC | 0.00% | Reduce -90.8% | 47,120 | $261K |
| Creative Planning | 0.00% | Add +91.3% | 45,923 | $254K |
| Allegheny Financial Group | 0.03% | No change | 42,900 | $238K |
| Canada Pension Plan Investment Board | 0.00% | Add +131.8% | 40,800 | $226K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 40,753 | $226K |
| Cwm, LLC | 0.00% | Add +30.9% | 39,652 | $220K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +28.2% | 36,028 | $200K |
| Fifth Third Bancorp | 0.00% | New | 35,398 | $196K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 35,034 | $194K |
| Persistent Asset Partners Ltd | 0.07% | Reduce -64.1% | 33,625 | $186K |
| Arizona State Retirement System | 0.00% | New | 32,753 | $181K |
| Gsa Capital Partners LLP | 0.01% | New | 31,694 | $176K |
| Lido Advisors, LLC | 0.00% | Reduce -11.3% | 31,000 | $172K |
| Citigroup Inc. | 0.00% | Add +30.4% | 30,817 | $171K |
| Intech Investment Management LLC | 0.00% | Reduce -29.6% | 29,929 | $166K |
| New York State Common Retirement Fund | 0.00% | No change | 29,568 | $164K |
| Mirabella Financial Services LLP | 0.02% | New | 28,739 | $159K |
| Virtu Financial LLC | 0.01% | New | 28,450 | $158K |
| KLP Kapitalforvaltning As | 0.00% | New | 26,300 | $146K |
| ProShare Advisors LLC | 0.00% | Add +3.6% | 25,595 | $142K |
| E Fund Management Co., Ltd. | 0.00% | — | 25,552 | $142K |
| AlphaCentric Advisors LLC | 0.14% | New | 24,518 | $136K |
| Barclays PLC | 0.00% | Reduce -91.6% | 24,291 | $135K |
| WINTON GROUP Ltd | 0.00% | Reduce -54.9% | 24,100 | $134K |
| SBI Securities Co., Ltd. | 0.00% | Add +92800.0% | 23,225 | $129K |
| TD Asset Management Inc | 0.00% | Reduce -51.4% | 22,760 | $126K |
| Voya Investment Management LLC | 0.00% | Add +15.1% | 22,227 | $123K |
| Cygnus Capital Advisors, LLC | 0.08% | Add +85.0% | 22,200 | $123K |
| Prelude Capital Management, LLC | 0.01% | Add +85.0% | 22,200 | $123K |
| CANADA LIFE ASSURANCE Co | 0.00% | New | 21,646 | $121K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +12.2% | 21,932 | $121K |
| Landscape Capital Management, L.L.C. | 0.01% | Add +114.8% | 21,512 | $119K |
| Quarry LP | 0.02% | Reduce -71.7% | 21,250 | $118K |
| Prudential Financial Inc. | 0.00% | New | 20,180 | $112K |
| Corient Private Wealth LP | 0.00% | Add +0.1% | 19,704 | $109K |
| Raymond James Financial Inc. | 0.00% | Reduce -22.1% | 19,369 | $107K |
| Mercer Global Advisors Inc. | 0.00% | Add +80.2% | 18,714 | $104K |
| Cerity Partners LLC | 0.00% | Add +21.5% | 17,979 | $100K |
| Scientech Research LLC | 0.08% | Add +0.6% | 17,316 | $96K |
| Coastal Bridge Advisors, LLC | 0.01% | No change | 17,000 | $94K |
| Quadrature Capital Ltd | 0.00% | Reduce -65.2% | 16,903 | $94K |
| Pictet Asset Management Holding SA | 0.00% | New | 16,701 | $93K |
| Fox Run Management, L.L.C. | 0.02% | New | 17,678 | $88K |
| Teacher Retirement System of Texas | 0.00% | New | 15,099 | $84K |
| Balefire, LLC | 0.02% | No change | 15,000 | $83K |
| ExodusPoint Capital Management, LP | 0.00% | New | 14,938 | $83K |
| Vontobel Holding Ltd. | 0.00% | New | 14,511 | $80K |
| Forefront Analytics, LLC | 0.07% | Add +7.7% | 14,240 | $79K |
| Magnetar Financial LLC | 0.00% | New | 14,205 | $79K |
| LPL Financial LLC | 0.00% | New | 13,214 | $73K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +0.3% | 12,936 | $72K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +544.8% | 12,677 | $70K |
| American Century Companies Inc. | 0.00% | Reduce -95.0% | 12,463 | $69K |
| nVerses Capital, LLC | 0.06% | New | 11,897 | $66K |
| Xponance LLC | 0.00% | New | 11,206 | $62K |
| Abel Hall, LLC | 0.01% | New | 10,921 | $61K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +11.4% | 10,790 | $60K |
| Merit Financial Group, LLC | 0.00% | New | 10,745 | $60K |
| Mount Vernon Associates Inc. | 0.04% | No change | 10,500 | $58K |
| Integrated Wealth Concepts LLC | 0.00% | New | 10,232 | $57K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -5.5% | 10,110 | $56K |
| Harbor Advisors LLC | 0.01% | No change | 10,000 | $55K |
| Shay Capital LLC | 0.01% | New | 10,000 | $55K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 7,549 | $42K |
| Nisa Investment Advisors, LLC | 0.00% | Add +183.7% | 7,413 | $41K |
| California State Teachers Retirement System | 0.00% | Add +16.4% | 7,173 | $40K |
| Geneos Wealth Management Inc. | 0.00% | No change | 6,000 | $33K |
| Sterling Capital Management LLC | 0.00% | Reduce -26.8% | 4,368 | $24K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.8% | 3,234 | $18K |
| Jones Financial Companies LLLP | 0.00% | Add +19.4% | 3,565 | $18K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 2,367 | $13K |
| Larson Financial Group LLC | 0.00% | Add +0.8% | 2,016 | $11K |
| Rockefeller Capital Management L.P. | 0.00% | Add +397.6% | 1,662 | $9K |
| Farther Finance Advisors, LLC | 0.00% | Add +341.8% | 1,365 | $7K |
| Osaic Holdings, Inc. | 0.00% | Reduce -99.1% | 1,269 | $7K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,132 | $6K |
| Optiver Holding B.V. | 0.00% | Add +111.7% | 1,122 | $6K |
| Essential Partners LLC | 0.00% | Add +0.5% | 1,092 | $6K |
| Royal Bank of Canada | 0.00% | Reduce -59.4% | 1,160 | $6K |
| Allworth Financial LP | 0.00% | Add +155.1% | 1,061 | $6K |
| Trask Adam Roland | 0.01% | — | 1,000 | $6K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -95.7% | 835 | $5K |
| MAI Capital Management | 0.00% | Add +1161.9% | 795 | $4K |
| Federated Hermes, Inc. | 0.00% | No change | 753 | $4K |
| IFP Advisors, Inc | 0.00% | Add +17.9% | 645 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +9.7% | 591 | $3K |
| Arax Advisory Partners | 0.00% | Add +2994.7% | 588 | $3K |
| Rothschild Investment LLC | 0.00% | Add +85.2% | 437 | $2K |
| True Wealth Design, LLC | 0.00% | Add +52.6% | 322 | $2K |
| GAMMA Investing LLC | 0.00% | New | 316 | $2K |
| Quantbot Technologies LP | 0.00% | New | 308 | $2K |
| HighMark Wealth Management LLC | 0.00% | No change | 300 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 269 | $1K |
| Sunbelt Securities, Inc. | 0.00% | No change | 110 | $609 |
| Root Financial Partners, LLC | 0.00% | New | 94 | $521 |
| Fortitude Family Office, LLC | 0.00% | New | 87 | $482 |
| US Bancorp \de | 0.00% | New | 77 | $427 |
| Advisory Services Network, LLC | 0.00% | New | 23 | $127 |
| Stone House Investment Management, LLC | 0.00% | New | 20 | $111 |
| SJS Investment Consulting Inc. | 0.00% | New | 17 | $95 |
| JPL Wealth Management, LLC | 0.00% | New | 13 | $73 |
"% of holder's portfolio" is ANNX's weight in each manager's 13F, not the share of Annexon Inc. the manager owns.