AnnexonANNX

13F holders, Q1 2026 (March 31)
217holders +49
58new positions
15sold out
6famous investors
$5.54avg. 13F price*

At the end of Q1 2026, 217 institutions reported holding Annexon Inc. (ANNX) in their 13F filings, up 49 from Q4 2025. 58 opened new positions and 15 sold out. The largest holders were Redmile Group, LLC ($80.6M), BlackRock, Inc. ($60.6M) and FMR LLC ($58.9M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Annexon Inc.
CUSIP
03589W102
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 127Q1 2024Q2 2024: 140Q2 2024Q3 2024: 142Q3 2024Q4 2024: 152Q4 2024Q1 2025: 147Q1 2025Q2 2025: 129Q2 2025Q3 2025: 144Q3 2025Q4 2025: 168Q4 2025Q1 2026: 217Q1 2026Q2 2026: 216Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions58$66.5M
Exits15$11.0M

All 13F filers, Q4 2025 → Q1 2026: 35,779,460 shares bought and 17,473,755 shares sold, net +18,305,705 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 217 holders

Redmile Group, LLC 5.34% Add +44.8% 14,549,768 $80.6M
BlackRock, Inc. 0.00% Add +22.1% 10,938,509 $60.6M
FMR LLC 0.00% Add +4.0% 10,635,648 $58.9M
BVF Inc. 1.54% Reduce -4.7% 8,698,173 $48.2M
State Street Corp. 0.00% Add +48.7% 6,919,255 $38.3M
Vanguard Capital Management LLC 0.00% — 5,956,589 $33.0M
Bain Capital Life Sciences Investors, LLC 2.61% Reduce -0.7% 5,212,674 $28.9M
Bellevue Group AG 0.68% No change 5,157,290 $28.6M
Mak Capital One LLC 4.33% Add +59.7% 4,724,043 $26.2M
Adage Capital Partners Gp, L.L.C. 0.04% Reduce -21.8% 4,300,000 $23.8M
Bank of America Corp. 0.00% Add +165.3% 4,259,995 $23.6M
Nuveen, LLC 0.01% Add +45.7% 4,246,330 $23.5M
Siren, L.L.C. 0.61% New 3,958,646 $21.9M
Balyasny Asset Management L.P. 0.04% Add +17.8% 3,886,909 $21.5M
Ameriprise Financial Inc. 0.00% Reduce -20.7% 3,449,121 $19.1M
Geode Capital Management, LLC 0.00% Add +16.4% 3,377,823 $18.7M
Qube Research & Technologies Ltd 0.02% Add +30.8% 3,114,314 $17.3M
Palo Alto Investors LP 2.50% Add +23.6% 2,948,090 $16.3M
Morgan Stanley 0.00% Reduce -4.2% 2,735,970 $15.2M
Great Point Partners LLC 3.39% New 2,500,000 $13.8M
Woodline Partners LP 0.05% Reduce -41.6% 2,337,137 $12.9M
Opaleye Management Inc. 1.70% Reduce -10.3% 2,331,761 $12.9M
Goldman Sachs Group Inc. 0.00% Add +21.7% 2,152,880 $11.9M
Point72 Asset Management 0.02% Add +404.3% 1,871,795 $10.4M
Vanguard Portfolio Management LLC 0.00% — 1,483,090 $8.2M
Y-Intercept (Hong Kong) Ltd 0.14% New 1,319,913 $7.3M
Tetragon Partners GP Ltd 1.41% Reduce -36.4% 1,292,455 $7.2M
UBS Group AG 0.00% Add +230.4% 1,245,941 $6.9M
Millennium Management 0.01% Reduce -56.3% 1,238,678 $6.9M
Charles Schwab Investment Management Inc. 0.00% Add +4.3% 1,102,445 $6.1M
Northern Trust Corp. 0.00% Add +37.2% 1,086,902 $6.0M
Dimensional Fund Advisors LP 0.00% Add +28.6% 924,078 $5.1M
Kennedy Capital Management LLC 0.11% Add +42.6% 912,323 $5.1M
Massachusetts Financial Services Co. 0.00% Reduce -0.0% 903,368 $5.0M
Vanguard Fiduciary Trust Co. 0.00% — 888,552 $4.9M
Marshall Wace, LLP 0.01% Add +65.3% 861,475 $4.8M
AQR Capital Management 0.00% Add +0.1% 777,253 $4.3M
Invesco Ltd. 0.00% Reduce -21.5% 763,005 $4.2M
Acadian Asset Management LLC 0.01% Reduce -12.0% 758,232 $4.2M
Russell Investments Group, Ltd. 0.00% Add +4.2% 711,380 $3.9M
D. E. Shaw & Co. 0.00% Reduce -32.8% 702,799 $3.9M
Wells Fargo & Company 0.00% Add +21.8% 698,739 $3.9M
Parkman Healthcare Partners LLC 0.39% Add +12.1% 674,013 $3.7M
Ensign Peak Advisors, Inc 0.01% New 625,097 $3.5M
Longaeva Partners L.P. 0.17% Reduce -80.0% 620,401 $3.4M
Citadel Advisors 0.00% Add +118.0% 600,135 $3.3M
Deerfield Management Company, L.P. 0.05% No change 583,913 $3.2M
Ikarian Capital, LLC 0.46% Add +152.0% 580,244 $3.2M
Sirios Capital Management L P 0.39% Reduce -19.0% 575,063 $3.2M
Deutsche Bank AG 0.00% Add +0.3% 562,181 $3.1M
Renaissance Technologies 0.00% Reduce -32.2% 544,300 $3.0M
Wellington Management Group LLP 0.00% Add +31.0% 521,379 $2.9M
Hennion & Walsh Asset Management, Inc. 0.10% Reduce -4.7% 509,689 $2.8M
Silverarc Capital Management, LLC 0.32% New 496,461 $2.8M
Board of Trustees of The Leland Stanford Junior University 0.32% No change 482,550 $2.7M
Two Sigma Investments, LP 0.00% Add +42.0% 471,391 $2.6M
Voloridge Investment Management, LLC 0.01% New 462,068 $2.6M
T. Rowe Price Associates Inc. 0.00% Reduce -3.7% 428,720 $2.4M
Mutual of America Capital Management LLC 0.03% Reduce -35.1% 416,698 $2.3M
Trexquant Investment LP 0.02% New 403,657 $2.2M
Bank of New York Mellon Corp 0.00% Add +9.2% 395,019 $2.2M
Susquehanna Portfolio Strategies, LLC 0.03% Add +1.0% 360,319 $2.0M
JPMorgan Chase & Co. 0.00% Add +502.8% 323,894 $1.6M
Cinctive Capital Management LP 0.10% Reduce -25.2% 268,640 $1.5M
BNP Paribas Financial Markets 0.00% Add +314.8% 255,371 $1.4M
Swiss National Bank 0.00% New 236,000 $1.3M
Rafferty Asset Management, LLC 0.00% Add +43.5% 203,269 $1.1M
Sei Investments Co. 0.00% Add +248.8% 203,236 $1.1M
Rosalind Advisors, Inc. 0.45% New 200,000 $1.1M
Ieq Capital, LLC 0.01% Add +7.0% 195,764 $1.1M
Ishara Investments LP 0.97% Reduce -76.8% 174,250 $965K
Engineers Gate Manager LP 0.01% New 174,141 $965K
J. Goldman & Co LP 0.04% Reduce -82.8% 170,817 $946K
Boothbay Fund Management, LLC 0.02% Add +159.3% 166,164 $921K
Rhumbline Advisers 0.00% Add +26.3% 159,670 $885K
Susquehanna International Group, LLP 0.00% Reduce -14.5% 158,640 $879K
Algert Global LLC 0.01% New 154,840 $858K
Jacobs Levy Equity Management, Inc. 0.00% Reduce -78.2% 148,941 $825K
Manufacturers Life Insurance Company, The 0.00% Add +3.6% 134,786 $747K
Diadema Partners LP 0.30% Reduce -62.0% 132,916 $736K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 130,647 $724K
Schonfeld Strategic Advisors LLC 0.01% Reduce -76.4% 123,282 $683K
DAFNA Capital Management LLC 0.15% Reduce -56.8% 117,812 $653K
Victory Capital Management Inc. 0.00% Add +682.9% 115,527 $640K
Man Group plc 0.00% New 109,222 $605K
Alliancebernstein L.P. 0.00% Reduce -15.4% 119,050 $598K
SCS Capital Management LLC 0.01% New 99,000 $548K
Bridgeway Capital Management, LLC 0.01% Reduce -29.0% 97,800 $542K
Connor, Clark & Lunn Investment Management Ltd. 0.00% New 92,707 $514K
Profund Advisors LLC 0.02% Add +71.6% 90,959 $504K
J. Safra Sarasin Holding AG 0.01% Reduce -23.2% 90,487 $501K
DNB Asset Management AS 0.00% Reduce -25.1% 88,617 $491K
XTX Topco Ltd 0.01% Reduce -66.9% 80,495 $446K
Legal & General Group Plc 0.00% Add +760.1% 80,046 $443K
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 79,486 $440K
Captrust Financial Advisors 0.00% Add +150.7% 79,173 $439K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +39.3% 76,257 $414K
MetLife Investment Management, LLC 0.00% Add +85.5% 72,444 $401K
Polen Capital Management LLC 0.00% New 70,152 $389K
Squarepoint Ops LLC 0.00% New 67,956 $376K
Los Angeles Capital Management LLC 0.00% New 62,073 $344K
Janus Henderson Group PLC 0.00% New 59,100 $328K
Brevan Howard Capital Management LP 0.00% Reduce -52.8% 58,433 $324K
Axq Capital, LP 0.04% Add +99.9% 58,185 $322K
China Universal Asset Management Co., Ltd. 0.02% Add +59.9% 57,683 $320K
STRS Ohio 0.00% New 55,500 $307K
ADAR1 Capital Management, LLC 0.02% Add +14.6% 55,000 $305K
Virtus Investment Advisers, LLC 0.08% Add +2.5% 54,866 $304K
DRW Securities, LLC 0.02% New 54,484 $302K
Vanguard Global Advisers, LLC 0.00% — 54,054 $299K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% New 53,867 $298K
Verdad Advisers, LP 0.33% New 53,277 $295K
Mariner, LLC 0.00% Add +69.9% 53,242 $295K
EntryPoint Capital, LLC 0.08% Add +20.2% 51,421 $285K
BIT Capital GmbH 0.02% New 50,000 $277K
State of Wisconsin Investment Board 0.00% New 49,746 $276K
Jane Street Group, LLC 0.00% Reduce -90.8% 47,120 $261K
Creative Planning 0.00% Add +91.3% 45,923 $254K
Allegheny Financial Group 0.03% No change 42,900 $238K
Canada Pension Plan Investment Board 0.00% Add +131.8% 40,800 $226K
State of New Jersey Common Pension Fund D 0.00% New 40,753 $226K
Cwm, LLC 0.00% Add +30.9% 39,652 $220K
Police & Firemen's Retirement System of New Jersey 0.00% Add +28.2% 36,028 $200K
Fifth Third Bancorp 0.00% New 35,398 $196K
Vanguard Investments Australia, Ltd. 0.00% — 35,034 $194K
Persistent Asset Partners Ltd 0.07% Reduce -64.1% 33,625 $186K
Arizona State Retirement System 0.00% New 32,753 $181K
Gsa Capital Partners LLP 0.01% New 31,694 $176K
Lido Advisors, LLC 0.00% Reduce -11.3% 31,000 $172K
Citigroup Inc. 0.00% Add +30.4% 30,817 $171K
Intech Investment Management LLC 0.00% Reduce -29.6% 29,929 $166K
New York State Common Retirement Fund 0.00% No change 29,568 $164K
Mirabella Financial Services LLP 0.02% New 28,739 $159K
Virtu Financial LLC 0.01% New 28,450 $158K
KLP Kapitalforvaltning As 0.00% New 26,300 $146K
ProShare Advisors LLC 0.00% Add +3.6% 25,595 $142K
E Fund Management Co., Ltd. 0.00% — 25,552 $142K
AlphaCentric Advisors LLC 0.14% New 24,518 $136K
Barclays PLC 0.00% Reduce -91.6% 24,291 $135K
WINTON GROUP Ltd 0.00% Reduce -54.9% 24,100 $134K
SBI Securities Co., Ltd. 0.00% Add +92800.0% 23,225 $129K
TD Asset Management Inc 0.00% Reduce -51.4% 22,760 $126K
Voya Investment Management LLC 0.00% Add +15.1% 22,227 $123K
Cygnus Capital Advisors, LLC 0.08% Add +85.0% 22,200 $123K
Prelude Capital Management, LLC 0.01% Add +85.0% 22,200 $123K
CANADA LIFE ASSURANCE Co 0.00% New 21,646 $121K
Wealth Enhancement Advisory Services, LLC 0.00% Add +12.2% 21,932 $121K
Landscape Capital Management, L.L.C. 0.01% Add +114.8% 21,512 $119K
Quarry LP 0.02% Reduce -71.7% 21,250 $118K
Prudential Financial Inc. 0.00% New 20,180 $112K
Corient Private Wealth LP 0.00% Add +0.1% 19,704 $109K
Raymond James Financial Inc. 0.00% Reduce -22.1% 19,369 $107K
Mercer Global Advisors Inc. 0.00% Add +80.2% 18,714 $104K
Cerity Partners LLC 0.00% Add +21.5% 17,979 $100K
Scientech Research LLC 0.08% Add +0.6% 17,316 $96K
Coastal Bridge Advisors, LLC 0.01% No change 17,000 $94K
Quadrature Capital Ltd 0.00% Reduce -65.2% 16,903 $94K
Pictet Asset Management Holding SA 0.00% New 16,701 $93K
Fox Run Management, L.L.C. 0.02% New 17,678 $88K
Teacher Retirement System of Texas 0.00% New 15,099 $84K
Balefire, LLC 0.02% No change 15,000 $83K
ExodusPoint Capital Management, LP 0.00% New 14,938 $83K
Vontobel Holding Ltd. 0.00% New 14,511 $80K
Forefront Analytics, LLC 0.07% Add +7.7% 14,240 $79K
Magnetar Financial LLC 0.00% New 14,205 $79K
LPL Financial LLC 0.00% New 13,214 $73K
Vanguard Personalized Indexing Management, LLC 0.00% Add +0.3% 12,936 $72K
Tower Research Capital LLC (TRC) 0.00% Add +544.8% 12,677 $70K
American Century Companies Inc. 0.00% Reduce -95.0% 12,463 $69K
nVerses Capital, LLC 0.06% New 11,897 $66K
Xponance LLC 0.00% New 11,206 $62K
Abel Hall, LLC 0.01% New 10,921 $61K
Ameritas Investment Partners, Inc. 0.00% Add +11.4% 10,790 $60K
Merit Financial Group, LLC 0.00% New 10,745 $60K
Mount Vernon Associates Inc. 0.04% No change 10,500 $58K
Integrated Wealth Concepts LLC 0.00% New 10,232 $57K
Cambridge Investment Research Advisors, Inc. 0.00% Reduce -5.5% 10,110 $56K
Harbor Advisors LLC 0.01% No change 10,000 $55K
Shay Capital LLC 0.01% New 10,000 $55K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +7.3% 7,549 $42K
Nisa Investment Advisors, LLC 0.00% Add +183.7% 7,413 $41K
California State Teachers Retirement System 0.00% Add +16.4% 7,173 $40K
Geneos Wealth Management Inc. 0.00% No change 6,000 $33K
Sterling Capital Management LLC 0.00% Reduce -26.8% 4,368 $24K
GF Fund Management Co. LTD. 0.00% Add +13.8% 3,234 $18K
Jones Financial Companies LLLP 0.00% Add +19.4% 3,565 $18K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% New 2,367 $13K
Larson Financial Group LLC 0.00% Add +0.8% 2,016 $11K
Rockefeller Capital Management L.P. 0.00% Add +397.6% 1,662 $9K
Farther Finance Advisors, LLC 0.00% Add +341.8% 1,365 $7K
Osaic Holdings, Inc. 0.00% Reduce -99.1% 1,269 $7K
PNC Financial Services Group, Inc. 0.00% No change 1,132 $6K
Optiver Holding B.V. 0.00% Add +111.7% 1,122 $6K
Essential Partners LLC 0.00% Add +0.5% 1,092 $6K
Royal Bank of Canada 0.00% Reduce -59.4% 1,160 $6K
Allworth Financial LP 0.00% Add +155.1% 1,061 $6K
Trask Adam Roland 0.01% — 1,000 $6K
Caitong International Asset Management Co., Ltd 0.00% Reduce -95.7% 835 $5K
MAI Capital Management 0.00% Add +1161.9% 795 $4K
Federated Hermes, Inc. 0.00% No change 753 $4K
IFP Advisors, Inc 0.00% Add +17.9% 645 $4K
EverSource Wealth Advisors, LLC 0.00% Add +9.7% 591 $3K
Arax Advisory Partners 0.00% Add +2994.7% 588 $3K
Rothschild Investment LLC 0.00% Add +85.2% 437 $2K
True Wealth Design, LLC 0.00% Add +52.6% 322 $2K
GAMMA Investing LLC 0.00% New 316 $2K
Quantbot Technologies LP 0.00% New 308 $2K
HighMark Wealth Management LLC 0.00% No change 300 $2K
Physician Wealth Advisors, Inc. 0.00% No change 269 $1K
Sunbelt Securities, Inc. 0.00% No change 110 $609
Root Financial Partners, LLC 0.00% New 94 $521
Fortitude Family Office, LLC 0.00% New 87 $482
US Bancorp \de 0.00% New 77 $427
Advisory Services Network, LLC 0.00% New 23 $127
Stone House Investment Management, LLC 0.00% New 20 $111
SJS Investment Consulting Inc. 0.00% New 17 $95
JPL Wealth Management, LLC 0.00% New 13 $73

"% of holder's portfolio" is ANNX's weight in each manager's 13F, not the share of Annexon Inc. the manager owns.