Apogee TherapeuticsAPGE

13F holders, Q1 2025 (March 31)
168holders +11
33new positions
21sold out
4famous investors
$37.43avg. 13F price*

At the end of Q1 2025, 168 institutions reported holding Apogee Therapeutics Inc. (APGE) in their 13F filings, up 11 from Q4 2024. 33 opened new positions and 21 sold out. The largest holders were Venrock Adviser, LLC ($317.3M), FMR LLC ($280.0M) and Wellington Management Group LLP ($204.9M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Apogee Therapeutics Inc.
CUSIP
03770N101
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 139Q1 2024Q2 2024: 139Q2 2024Q3 2024: 139Q3 2024Q4 2024: 157Q4 2024Q1 2025: 168Q1 2025Q2 2025: 182Q2 2025Q3 2025: 174Q3 2025Q4 2025: 207Q4 2025Q1 2026: 224Q1 2026Q2 2026: 288Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions33$29.7M
Exits21$38.2M

All 13F filers, Q4 2024 → Q1 2025: 6,919,562 shares bought and 3,272,591 shares sold, net +3,646,971 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 168 holders

Venrock Adviser, LLC 27.00% No change 8,493,321 $317.3M
FMR LLC 0.02% Reduce -0.1% 7,493,626 $280.0M
Wellington Management Group LLP 0.04% Add +21.4% 5,485,754 $204.9M
BlackRock, Inc. 0.00% Reduce -4.4% 2,910,829 $108.7M
RTW Investments, LP 1.55% No change 2,712,097 $101.3M
Driehaus Capital Management LLC 0.84% Reduce -10.2% 2,339,563 $87.4M
Vanguard Group Inc. 0.00% Reduce -0.7% 2,082,606 $77.8M
Fairmount Funds Management LLC 11.87% No change 2,048,647 $76.5M
Janus Henderson Group PLC 0.04% Add +58.0% 1,793,833 $71.3M
Mercer Global Advisors Inc. 0.14% Add +127.8% 1,640,180 $61.3M
Ra Capital Management, L.P. 0.98% No change 1,569,491 $58.6M
Braidwell LP 3.00% No change 1,540,362 $57.5M
State Street Corp. 0.00% Reduce -10.4% 1,313,750 $49.1M
Alliancebernstein L.P. 0.02% Reduce -5.5% 1,280,950 $47.9M
Affinity Asset Advisors, LLC 7.13% Add +23.6% 1,151,199 $43.0M
Perceptive Advisors LLC 1.49% Add +7.2% 1,122,767 $41.9M
Woodline Partners LP 0.26% Add +4.5% 1,061,053 $39.6M
JPMorgan Chase & Co. 0.00% Add +2483.9% 962,631 $36.0M
Paradigm Biocapital Advisors LP 1.65% Reduce -25.1% 961,707 $35.9M
Franklin Resources Inc. 0.01% Add +1.1% 876,076 $32.7M
Geode Capital Management, LLC 0.00% Add +2.4% 835,695 $31.2M
T. Rowe Price Associates Inc. 0.00% Reduce -21.9% 821,850 $30.7M
Adage Capital Partners Gp, L.L.C. 0.05% Add +202.7% 727,000 $27.2M
UBS Group AG 0.01% Add +29.7% 701,909 $26.2M
Siren, L.L.C. 1.25% Reduce -20.4% 594,994 $22.2M
Polar Capital Holdings Plc 0.13% New 550,000 $20.5M
Morgan Stanley 0.00% Add +148.1% 519,939 $19.4M
Barclays PLC 0.01% Add +4.6% 498,625 $18.6M
Bank of America Corp. 0.00% Add +303.5% 425,880 $15.9M
Jefferies Financial Group Inc. 0.28% Reduce -52.5% 421,796 $15.8M
Point72 Asset Management 0.04% Add +29.6% 392,488 $14.7M
Northern Trust Corp. 0.00% Reduce -3.9% 314,478 $11.7M
Jennison Associates LLC 0.01% Reduce -6.0% 293,757 $11.0M
Goldman Sachs Group Inc. 0.00% Reduce -28.8% 290,699 $10.9M
Commodore Capital LP 0.80% No change 290,000 $10.8M
Charles Schwab Investment Management Inc. 0.00% Reduce -2.0% 271,879 $10.2M
Millennium Management 0.01% Add +100.0% 260,335 $9.7M
Two Sigma Investments, LP 0.02% Reduce -5.4% 252,135 $9.4M
Victory Capital Management Inc. 0.01% Add +4.5% 232,983 $8.7M
First Turn Management, LLC 1.73% Reduce -9.1% 229,675 $8.6M
Bank of New York Mellon Corp 0.00% Add +93.3% 214,231 $8.0M
Tang Capital Management LLC 0.41% Add +100.0% 200,000 $7.5M
Capital World Investors 0.00% Reduce -5.5% 193,895 $7.2M
Blackstone Inc. 0.03% Add +129.7% 183,747 $6.9M
Voloridge Investment Management, LLC 0.02% Add +308.7% 167,991 $6.3M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% Reduce -11.6% 127,208 $4.8M
Balyasny Asset Management L.P. 0.01% New 112,730 $4.2M
Nuveen, LLC 0.00% — 110,855 $4.1M
Allostery Investments LP 5.93% Add +10.0% 110,000 $4.1M
ArrowMark Colorado Holdings LLC 0.07% No change 109,410 $4.1M
Frontier Capital Management Co. LLC 0.04% Reduce -37.0% 108,817 $4.1M
Granahan Investment Management, LLC 0.20% Add +16.7% 108,340 $4.0M
ADAR1 Capital Management, LLC 0.78% Add +154.0% 104,853 $3.9M
Schroder Investment Management Group 0.00% Add +65.9% 96,992 $3.9M
TD Asset Management Inc 0.00% Reduce -19.8% 101,388 $3.8M
Ameriprise Financial Inc. 0.00% Add +1587.0% 96,326 $3.6M
Platinum Investment Management Ltd. 0.21% No change 95,646 $3.6M
Manufacturers Life Insurance Company, The 0.00% Reduce -0.7% 87,347 $3.3M
Kennedy Capital Management LLC 0.07% Add +8.4% 78,397 $2.9M
Susquehanna International Group, LLP 0.00% Add +124.8% 70,338 $2.6M
Two Sigma Advisers, LP 0.01% Reduce -5.3% 67,700 $2.5M
Citadel Advisors 0.00% Reduce -9.0% 66,182 $2.5M
Citigroup Inc. 0.00% Add +9.4% 61,362 $2.3M
Rhumbline Advisers 0.00% Add +3.2% 54,385 $2.0M
Parkman Healthcare Partners LLC 0.21% Reduce -45.1% 46,663 $1.7M
Swiss National Bank 0.00% Reduce -1.6% 43,600 $1.6M
HighVista Strategies LLC 0.62% No change 43,190 $1.6M
Rafferty Asset Management, LLC 0.01% Reduce -25.4% 43,001 $1.6M
Diadema Partners LP 1.19% Reduce -21.0% 40,000 $1.5M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +10.7% 35,726 $1.3M
Alps Advisors Inc. 0.01% Reduce -9.1% 33,096 $1.2M
B Group, Inc. 0.97% Add +100.0% 30,000 $1.1M
Dark Forest Capital Management LP 0.05% New 29,871 $1.1M
Polymer Capital Management (HK) LTD 0.19% New 29,268 $1.1M
Deutsche Bank AG 0.00% Reduce -9.0% 28,869 $1.1M
Legal & General Group Plc 0.00% Reduce -0.3% 25,782 $963K
Erste Asset Management GmbH 0.01% No change 24,000 $953K
Prudential Financial Inc. 0.00% Add +1.5% 24,905 $930K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +2.9% 24,529 $921K
Invesco Ltd. 0.00% Add +14.4% 24,310 $908K
Twinbeech Capital LP 0.02% New 24,298 $908K
MetLife Investment Management, LLC 0.00% Reduce -1.6% 22,605 $845K
California State Teachers Retirement System 0.00% No change 22,178 $829K
Voya Investment Management LLC 0.00% Reduce -53.4% 21,427 $801K
Corebridge Financial, Inc. 0.00% Reduce -1.5% 18,563 $694K
Intech Investment Management LLC 0.01% Add +8.8% 18,417 $688K
Wells Fargo & Company 0.00% Add +2.3% 18,104 $676K
XTX Topco Ltd 0.03% Add +170.8% 17,188 $642K
Squarepoint Ops LLC 0.00% Reduce -55.3% 16,232 $606K
Soleus Capital Management, L.P. 0.05% Reduce -77.1% 16,000 $598K
Comerica Bank 0.00% Reduce -25.2% 15,360 $574K
Natixis Advisors, LLC 0.00% Add +1.6% 15,016 $561K
Jane Street Group, LLC 0.00% Add +146.8% 13,742 $513K
New York State Common Retirement Fund 0.00% No change 12,187 $455K
Teachers Retirement System of the State of Kentucky 0.00% No change 11,644 $435K
Marshall Wace, LLP 0.00% Reduce -84.7% 11,599 $433K
Jain Global LLC 0.01% New 11,586 $433K
ProShare Advisors LLC 0.00% Reduce -20.1% 10,235 $382K
State Board of Administration of Florida Retirement System 0.00% No change 9,350 $349K
Profund Advisors LLC 0.01% Reduce -19.4% 9,215 $344K
Persistent Asset Partners Ltd 0.30% Reduce -48.8% 9,178 $343K
China Universal Asset Management Co., Ltd. 0.03% Reduce -5.4% 9,032 $337K
D. E. Shaw & Co. 0.00% Reduce -10.6% 8,776 $328K
State of Wisconsin Investment Board 0.00% Reduce -36.6% 8,491 $317K
Cibc World Markets Corp. 0.00% New 8,408 $314K
Police & Firemen's Retirement System of New Jersey 0.00% No change 8,126 $304K
Birchview Capital, LP 0.26% New 8,000 $299K
Global Endowment Management, LP 0.04% No change 7,797 $291K
Handelsbanken Fonder AB 0.00% No change 7,500 $280K
Family Manage LLC 0.04% Reduce -2.2% 6,860 $256K
Commonwealth Equity Services, LLC 0.00% Add +32.5% 6,502 $243K
Arizona State Retirement System 0.00% Reduce -1.0% 6,452 $241K
Teacher Retirement System of Texas 0.00% Reduce -9.4% 6,060 $226K
Engineers Gate Manager LP 0.00% New 5,988 $224K
Glenmede Trust Co. NA 0.00% Reduce -0.1% 5,915 $221K
KLP Kapitalforvaltning As 0.00% No change 5,000 $187K
Ameritas Investment Partners, Inc. 0.00% No change 3,839 $143K
Virtus Investment Advisers, LLC 0.04% New 3,701 $138K
Wexford Capital LP 0.03% New 2,879 $108K
BNP Paribas Financial Markets 0.00% Reduce -43.9% 2,708 $101K
Point72 Asia (Singapore) Pte. Ltd. 0.03% New 2,584 $97K
Caption Management, LLC 0.00% New 2,415 $90K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +0.5% 1,507 $60K
Point72 (DIFC) Ltd 0.01% Reduce -92.9% 1,583 $59K
Amalgamated Bank 0.00% Add +4.9% 1,312 $49K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 1,207 $45K
GF Fund Management Co. LTD. 0.00% Add +22.0% 1,153 $43K
AlphaQuest LLC 0.00% New 1,141 $43K
Brooklyn Investment Group 0.01% New 1,134 $42K
Tower Research Capital LLC (TRC) 0.00% Reduce -84.3% 985 $37K
Aster Capital Management (DIFC) Ltd 0.01% Add +1066.7% 1,050 $33K
Group One Trading LLC 0.00% Reduce -39.2% 805 $30K
BI Asset Management Fondsmaeglerselskab A/S 0.00% New 681 $25K
ANTIPODES PARTNERS Ltd 0.00% New 542 $20K
Versant Capital Management, Inc 0.00% New 434 $16K
Nisa Investment Advisors, LLC 0.00% Reduce -9.8% 386 $14K
Russell Investments Group, Ltd. 0.00% Add +8.5% 204 $8K
Farther Finance Advisors, LLC 0.00% New 161 $6K
GAMMA Investing LLC 0.00% Reduce -2.0% 145 $5K
Daiwa Securities Group Inc. 0.00% Reduce -23.4% 131 $5K
Washington Trust Advisors, Inc. 0.00% No change 96 $4K
Red Tortoise LLC 0.00% No change 94 $4K
Rothschild Investment LLC 0.00% Add +240.0% 85 $3K
Leonteq Securities AG 0.00% New 73 $3K
Coldstream Capital Management Inc. 0.00% New 54 $2K
Lindbrook Capital, LLC 0.00% Add +390.9% 54 $2K
Royal Bank of Canada 0.00% Reduce -93.7% 49 $2K
US Bancorp \de 0.00% Add +880.0% 49 $2K
Sterling Capital Management LLC 0.00% No change 39 $1K
Bellevue Asset Management, LLC 0.00% No change 36 $1K
Amundi 0.00% Add +191.7% 35 $1K
Rise Advisors, LLC 0.00% New 31 $1K
Larson Financial Group LLC 0.00% New 30 $1K
PNC Financial Services Group, Inc. 0.00% New 27 $1K
Cwm, LLC 0.00% Reduce -15.8% 16 $1K
Arax Advisory Partners 0.00% New 26 $972
Sierra Ocean, LLC 0.00% New 25 $934
Signaturefd, LLC 0.00% New 25 $934
Stephens Consulting, LLC 0.00% New 10 $374
Parkside Financial Bank & Trust 0.00% New 10 $374
Federation des caisses Desjardins du Quebec 0.00% No change 10 $374
EverSource Wealth Advisors, LLC 0.00% Reduce -36.4% 7 $262
WealthTrak Capital Management LLC 0.00% New 5 $187
SouthState Bank Corp 0.00% New 5 $187
Quantbot Technologies LP 0.00% New 5 $187
Osaic Holdings, Inc. 0.00% Reduce -85.7% 2 $75
True Wealth Design, LLC 0.00% New 1 $38
Covestor Ltd 0.00% No change 3 $0

"% of holder's portfolio" is APGE's weight in each manager's 13F, not the share of Apogee Therapeutics Inc. the manager owns.