Compass TherapeuticsCMPX

13F holders, Q4 2025 (December 31)
173holders +48
53new positions
10sold out
4famous investors
$5.37avg. 13F price*

At the end of Q4 2025, 173 institutions reported holding Compass Therapeutics Inc. (CMPX) in their 13F filings, up 48 from Q3 2025. 53 opened new positions and 10 sold out. The largest holders were Tang Capital Management LLC ($90.2M), Orbimed Advisors LLC ($81.7M) and Montanova Capital, LLC ($76.2M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Compass Therapeutics Inc.
CUSIP
20454B104
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 78Q1 2024Q2 2024: 82Q2 2024Q3 2024: 79Q3 2024Q4 2024: 92Q4 2024Q1 2025: 108Q1 2025Q2 2025: 103Q2 2025Q3 2025: 125Q3 2025Q4 2025: 173Q4 2025Q1 2026: 201Q1 2026Q2 2026: 215Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions53$85.1M
Exits10$22.4M

All 13F filers, Q3 2025 → Q4 2025: 30,450,569 shares bought and 20,516,151 shares sold, net +9,934,418 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 173 holders

Tang Capital Management LLC 4.45% Reduce -0.1% 16,790,809 $90.2M
Orbimed Advisors LLC 1.67% No change 15,219,994 $81.7M
Montanova Capital, LLC 1.90% Add +0.6% 14,182,379 $76.2M
Vivo Capital, LLC 3.31% No change 9,545,466 $51.3M
BlackRock, Inc. 0.00% Add +27.4% 9,388,624 $50.4M
Vanguard Group Inc. 0.00% Add +13.9% 8,048,374 $43.2M
Enavate Sciences Gp, LLC 8.25% No change 7,788,150 $41.8M
BVF Inc. 1.40% Add +63.5% 7,764,842 $41.7M
Blackstone Inc. 0.14% Reduce -37.7% 6,126,182 $32.9M
State Street Corp. 0.00% Add +57.4% 4,890,525 $26.3M
Adage Capital Partners Gp, L.L.C. 0.04% Reduce -14.5% 4,436,500 $23.8M
Rock Springs Capital Management LP 1.09% Reduce -12.2% 3,927,202 $21.1M
Deerfield Management Company, L.P. 0.28% New 3,606,000 $19.4M
Geode Capital Management, LLC 0.00% Add +18.9% 3,502,526 $18.8M
Blue Owl Capital Holdings LP 5.80% Add +33.8% 3,466,525 $18.6M
Sofinnova Investments, Inc. 0.78% Add +65.9% 3,365,446 $18.1M
Millennium Management 0.01% Reduce -4.0% 3,109,286 $16.7M
Braidwell LP 0.57% New 2,786,778 $15.0M
FMR LLC 0.00% Reduce -37.6% 2,579,711 $13.9M
Palo Alto Investors LP 1.89% New 2,532,419 $13.6M
RTW Investments, LP 0.13% No change 2,500,000 $13.4M
Balyasny Asset Management L.P. 0.02% Reduce -43.6% 1,593,275 $8.6M
Birchview Capital, LP 5.01% Add +82.5% 1,592,938 $8.6M
Goldman Sachs Group Inc. 0.00% Add +46.0% 1,517,415 $8.1M
Trails Edge Capital Partners, LP 1.88% — 1,415,273 $7.6M
Marshall Wace, LLP 0.01% New 1,263,647 $6.8M
Logos Global Management LP 0.41% Reduce -43.9% 1,150,000 $6.2M
NEXTBio Capital Management LP 3.51% — 1,114,005 $6.0M
Acuta Capital Partners, LLC 3.99% Add +30.1% 1,093,300 $5.9M
Silverarc Capital Management, LLC 0.82% Reduce -62.9% 1,051,343 $5.6M
Monashee Investment Management LLC 3.17% Reduce -20.0% 1,000,000 $5.4M
Northern Trust Corp. 0.00% Add +12.9% 972,935 $5.2M
JPMorgan Chase & Co. 0.00% Reduce -56.5% 870,014 $4.7M
Ameriprise Financial Inc. 0.00% New 823,174 $4.4M
Ikarian Capital, LLC 0.56% New 800,000 $4.3M
Burkehill Global Management, LP 0.26% No change 700,000 $3.8M
Barclays PLC 0.00% Add +167.4% 594,776 $3.2M
Atle Fund Management AB 1.00% New 584,332 $3.1M
Seven Fleet Capital Management LP 2.07% — 568,747 $3.1M
Y-Intercept (Hong Kong) Ltd 0.06% New 462,166 $2.5M
Schonfeld Strategic Advisors LLC 0.01% Reduce -5.0% 452,442 $2.4M
Qube Research & Technologies Ltd 0.00% New 441,805 $2.4M
Charles Schwab Investment Management Inc. 0.00% Add +22.3% 410,157 $2.2M
Morgan Stanley 0.00% Add +95.4% 365,245 $2.0M
Dimensional Fund Advisors LP 0.00% Add +94.6% 341,596 $1.8M
Wellington Management Group LLP 0.00% Reduce -0.4% 316,849 $1.7M
Prudential Financial Inc. 0.00% New 314,750 $1.7M
Bank of New York Mellon Corp 0.00% Add +40.0% 312,480 $1.7M
Nuveen, LLC 0.00% Add +11.5% 288,924 $1.6M
Royce & Associates LP 0.02% New 285,988 $1.5M
Bank of America Corp. 0.00% Add +261.0% 266,434 $1.4M
Citigroup Inc. 0.00% Add +2358.7% 261,876 $1.4M
HighVista Strategies LLC 0.34% New 245,532 $1.3M
Arrowstreet Capital, Limited Partnership 0.00% New 210,249 $1.1M
Boothbay Fund Management, LLC 0.03% New 205,024 $1.1M
Connor, Clark & Lunn Investment Management Ltd. 0.00% New 191,724 $1.0M
State of Wisconsin Investment Board 0.00% Add +347.9% 185,423 $996K
UBS Group AG 0.00% Reduce -15.3% 167,856 $901K
AQR Capital Management 0.00% Add +162.4% 155,218 $834K
Rafferty Asset Management, LLC 0.00% Add +113.8% 151,743 $815K
Alps Advisors Inc. 0.00% Add +75.9% 146,040 $784K
Wells Fargo & Company 0.00% Add +112.4% 144,798 $778K
ADAR1 Capital Management, LLC 0.06% Add +178.0% 139,000 $746K
Rhumbline Advisers 0.00% Reduce -3.4% 134,605 $723K
Gsa Capital Partners LLP 0.06% New 133,810 $719K
Squarepoint Ops LLC 0.00% Add +43.6% 126,192 $678K
Brevan Howard Capital Management LP 0.01% Add +158.4% 118,528 $636K
XTX Topco Ltd 0.02% Add +582.2% 115,634 $621K
Deutsche Bank AG 0.00% Add +14.1% 109,273 $587K
Creative Planning 0.00% Add +77.5% 108,144 $581K
SG Americas Securities, LLC 0.00% Reduce -28.6% 106,533 $572K
Citadel Advisors 0.00% Reduce -54.7% 105,682 $568K
NEOS Investment Management LLC 0.00% New 101,676 $546K
Tema ETFs LLC 0.04% New 100,176 $538K
CM Management, LLC 0.45% Reduce -33.3% 100,000 $537K
Alliancebernstein L.P. 0.00% Reduce -19.4% 83,940 $451K
SummitTX Capital, L.P. 0.01% New 81,449 $437K
Raymond James Financial Inc. 0.00% New 80,142 $430K
Atom Investors LP 0.03% Reduce -27.6% 77,281 $415K
MetLife Investment Management, LLC 0.00% Add +26.8% 73,985 $397K
T. Rowe Price Associates Inc. 0.00% Add +24.6% 70,488 $379K
Jane Street Group, LLC 0.00% Add +121.2% 70,063 $376K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +39.6% 69,576 $374K
Franklin Resources Inc. 0.00% New 66,607 $358K
Invesco Ltd. 0.00% Add +5.3% 63,901 $343K
Persistent Asset Partners Ltd 0.15% New 57,253 $307K
Profund Advisors LLC 0.01% Add +247.6% 57,246 $307K
Graham Capital Management, L.P. 0.01% New 53,427 $287K
Virtus Investment Advisers, LLC 0.08% New 51,556 $277K
D. E. Shaw & Co. 0.00% New 51,482 $276K
Susquehanna International Group, LLP 0.00% Add +124.2% 44,742 $240K
LPL Financial LLC 0.00% Add +4.7% 44,470 $239K
Axq Capital, LP 0.05% New 41,378 $222K
American Century Companies Inc. 0.00% New 40,412 $217K
Manufacturers Life Insurance Company, The 0.00% Add +21.6% 40,325 $217K
Intech Investment Management LLC 0.00% No change 38,936 $209K
Police & Firemen's Retirement System of New Jersey 0.00% Add +25.3% 35,503 $191K
SmartHarvest Portfolios, LLC 0.06% — 34,715 $186K
Simplicity Wealth,LLC 0.01% Reduce -8.6% 33,869 $182K
New York State Common Retirement Fund 0.00% No change 30,407 $163K
Caxton Corp. 3.70% Reduce -44.9% 29,495 $158K
Avanza Fonder AB 0.00% New 27,347 $147K
Walleye Trading LLC 0.00% No change 25,000 $134K
Caitong International Asset Management Co., Ltd 0.03% New 24,579 $132K
DV Trading LLC 0.01% — 24,207 $130K
Stifel Financial Corp. 0.00% New 23,973 $129K
ProShare Advisors LLC 0.00% Add +41.0% 23,972 $129K
Abel Hall, LLC 0.03% New 22,882 $123K
Independent Financial Group, LLC 0.00% New 22,779 $122K
Voya Investment Management LLC 0.00% Add +31.5% 22,629 $122K
Captrust Financial Advisors 0.00% Add +1.6% 20,846 $112K
Welch & Forbes LLC 0.00% Add +26.7% 19,000 $102K
Focus Partners Wealth 0.00% Add +17.6% 18,595 $100K
Independent Advisor Alliance 0.00% No change 17,894 $96K
Sig Brokerage, LP 0.03% Reduce -35.2% 17,076 $92K
Sequoia Financial Advisors, LLC 0.00% Add +0.9% 15,894 $85K
BNP Paribas Financial Markets 0.00% Reduce -19.9% 15,645 $84K
Two Sigma Advisers, LP 0.00% New 15,200 $82K
Canada Pension Plan Investment Board 0.00% New 14,900 $80K
M&T Bank Corp 0.00% New 14,894 $80K
Victory Capital Management Inc. 0.00% Add +13.1% 14,311 $77K
Rovin Capital /Ut/ 0.02% No change 13,495 $72K
EntryPoint Capital, LLC 0.03% New 13,163 $71K
Neuberger Berman Group LLC 0.00% New 12,807 $69K
Legal & General Group Plc 0.00% Add +32.3% 12,753 $68K
North Star Investment Management Corp. 0.00% No change 12,500 $67K
Quadrature Capital Ltd 0.00% Reduce -74.1% 12,293 $66K
Strategic Wealth Partners, Ltd. 0.00% No change 12,100 $65K
Russell Investments Group, Ltd. 0.00% Add +48.5% 11,558 $62K
Ameritas Investment Partners, Inc. 0.00% Add +40.9% 10,621 $57K
Stonebrook Private Inc. 0.01% No change 10,230 $55K
Xponance LLC 0.00% New 10,201 $55K
Cygnus Capital Advisors, LLC 0.04% — 10,000 $54K
Prelude Capital Management, LLC 0.00% New 10,000 $54K
Simplex Trading, LLC 0.00% Add +117.7% 8,912 $48K
California State Teachers Retirement System 0.00% Add +8.9% 8,056 $43K
Flagship Harbor Advisors, LLC 0.00% New 6,000 $32K
MCF Advisors LLC 0.00% No change 5,540 $30K
Nisa Investment Advisors, LLC 0.00% No change 5,248 $28K
Group One Trading LLC 0.00% New 5,244 $28K
Acadian Asset Management LLC 0.00% New 4,867 $26K
Fortitude Family Office, LLC 0.01% Reduce -7.8% 4,591 $25K
EverSource Wealth Advisors, LLC 0.00% Reduce -29.8% 4,370 $23K
Amalgamated Bank 0.00% Add +33.6% 4,111 $22K
Royal Bank of Canada 0.00% Reduce -99.8% 3,821 $21K
Sterling Capital Management LLC 0.00% Add +14.8% 3,827 $21K
VSM Wealth Advisory, LLC 0.00% New 3,000 $16K
Cwm, LLC 0.00% Add +61.8% 3,059 $16K
Rockefeller Capital Management L.P. 0.00% New 2,042 $11K
Cape Investment Advisory, Inc. 0.00% Add +52.0% 2,002 $11K
Tower Research Capital LLC (TRC) 0.00% Reduce -71.9% 1,698 $9K
Optiver Holding B.V. 0.00% Reduce -33.3% 1,096 $6K
Farther Finance Advisors, LLC 0.00% Add +75.3% 680 $4K
Bessemer Group Inc. 0.00% No change 526 $3K
Federation des caisses Desjardins du Quebec 0.00% New 500 $3K
PNC Financial Services Group, Inc. 0.00% Reduce -92.9% 413 $2K
Quadrant Capital Group LLC 0.00% No change 405 $2K
National Bank of Canada 0.00% New 242 $1K
SBI Securities Co., Ltd. 0.00% Reduce -28.2% 237 $1K
Marshall & Sterling Wealth Advisors Inc. 0.00% No change 200 $1K
Rothschild Investment LLC 0.00% Add +36.7% 164 $881
Smartleaf Asset Management LLC 0.00% New 69 $371
Osaic Holdings, Inc. 0.00% New 57 $306
CIBC Private Wealth Group LLC 0.00% New 38 $204
GAMMA Investing LLC 0.00% New 29 $156
SJS Investment Consulting Inc. 0.00% New 27 $145
MAI Capital Management 0.00% New 24 $129
Allworth Financial LP 0.00% Add +400.0% 20 $108
Arax Advisory Partners 0.00% Reduce -92.0% 18 $97
Essential Partners LLC 0.00% Reduce -52.6% 9 $48
Sunbelt Securities, Inc. 0.00% No change 8 $43
IFP Advisors, Inc 0.00% No change 6 $32
Hughes Financial Services, LLC 0.00% New 1 $5

"% of holder's portfolio" is CMPX's weight in each manager's 13F, not the share of Compass Therapeutics Inc. the manager owns.