Compass TherapeuticsCMPX
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 173 institutions reported holding Compass Therapeutics Inc. (CMPX) in their 13F filings, up 48 from Q3 2025. 53 opened new positions and 10 sold out. The largest holders were Tang Capital Management LLC ($90.2M), Orbimed Advisors LLC ($81.7M) and Montanova Capital, LLC ($76.2M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Compass Therapeutics Inc.
- CUSIP
- 20454B104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 53 | $85.1M |
| Exits | 10 | $22.4M |
All 13F filers, Q3 2025 → Q4 2025: 30,450,569 shares bought and 20,516,151 shares sold, net +9,934,418 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 173 holders
| Tang Capital Management LLC | 4.45% | Reduce -0.1% | 16,790,809 | $90.2M |
| Orbimed Advisors LLC | 1.67% | No change | 15,219,994 | $81.7M |
| Montanova Capital, LLC | 1.90% | Add +0.6% | 14,182,379 | $76.2M |
| Vivo Capital, LLC | 3.31% | No change | 9,545,466 | $51.3M |
| BlackRock, Inc. | 0.00% | Add +27.4% | 9,388,624 | $50.4M |
| Vanguard Group Inc. | 0.00% | Add +13.9% | 8,048,374 | $43.2M |
| Enavate Sciences Gp, LLC | 8.25% | No change | 7,788,150 | $41.8M |
| BVF Inc. | 1.40% | Add +63.5% | 7,764,842 | $41.7M |
| Blackstone Inc. | 0.14% | Reduce -37.7% | 6,126,182 | $32.9M |
| State Street Corp. | 0.00% | Add +57.4% | 4,890,525 | $26.3M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Reduce -14.5% | 4,436,500 | $23.8M |
| Rock Springs Capital Management LP | 1.09% | Reduce -12.2% | 3,927,202 | $21.1M |
| Deerfield Management Company, L.P. | 0.28% | New | 3,606,000 | $19.4M |
| Geode Capital Management, LLC | 0.00% | Add +18.9% | 3,502,526 | $18.8M |
| Blue Owl Capital Holdings LP | 5.80% | Add +33.8% | 3,466,525 | $18.6M |
| Sofinnova Investments, Inc. | 0.78% | Add +65.9% | 3,365,446 | $18.1M |
| Millennium Management | 0.01% | Reduce -4.0% | 3,109,286 | $16.7M |
| Braidwell LP | 0.57% | New | 2,786,778 | $15.0M |
| FMR LLC | 0.00% | Reduce -37.6% | 2,579,711 | $13.9M |
| Palo Alto Investors LP | 1.89% | New | 2,532,419 | $13.6M |
| RTW Investments, LP | 0.13% | No change | 2,500,000 | $13.4M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -43.6% | 1,593,275 | $8.6M |
| Birchview Capital, LP | 5.01% | Add +82.5% | 1,592,938 | $8.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +46.0% | 1,517,415 | $8.1M |
| Trails Edge Capital Partners, LP | 1.88% | — | 1,415,273 | $7.6M |
| Marshall Wace, LLP | 0.01% | New | 1,263,647 | $6.8M |
| Logos Global Management LP | 0.41% | Reduce -43.9% | 1,150,000 | $6.2M |
| NEXTBio Capital Management LP | 3.51% | — | 1,114,005 | $6.0M |
| Acuta Capital Partners, LLC | 3.99% | Add +30.1% | 1,093,300 | $5.9M |
| Silverarc Capital Management, LLC | 0.82% | Reduce -62.9% | 1,051,343 | $5.6M |
| Monashee Investment Management LLC | 3.17% | Reduce -20.0% | 1,000,000 | $5.4M |
| Northern Trust Corp. | 0.00% | Add +12.9% | 972,935 | $5.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -56.5% | 870,014 | $4.7M |
| Ameriprise Financial Inc. | 0.00% | New | 823,174 | $4.4M |
| Ikarian Capital, LLC | 0.56% | New | 800,000 | $4.3M |
| Burkehill Global Management, LP | 0.26% | No change | 700,000 | $3.8M |
| Barclays PLC | 0.00% | Add +167.4% | 594,776 | $3.2M |
| Atle Fund Management AB | 1.00% | New | 584,332 | $3.1M |
| Seven Fleet Capital Management LP | 2.07% | — | 568,747 | $3.1M |
| Y-Intercept (Hong Kong) Ltd | 0.06% | New | 462,166 | $2.5M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -5.0% | 452,442 | $2.4M |
| Qube Research & Technologies Ltd | 0.00% | New | 441,805 | $2.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +22.3% | 410,157 | $2.2M |
| Morgan Stanley | 0.00% | Add +95.4% | 365,245 | $2.0M |
| Dimensional Fund Advisors LP | 0.00% | Add +94.6% | 341,596 | $1.8M |
| Wellington Management Group LLP | 0.00% | Reduce -0.4% | 316,849 | $1.7M |
| Prudential Financial Inc. | 0.00% | New | 314,750 | $1.7M |
| Bank of New York Mellon Corp | 0.00% | Add +40.0% | 312,480 | $1.7M |
| Nuveen, LLC | 0.00% | Add +11.5% | 288,924 | $1.6M |
| Royce & Associates LP | 0.02% | New | 285,988 | $1.5M |
| Bank of America Corp. | 0.00% | Add +261.0% | 266,434 | $1.4M |
| Citigroup Inc. | 0.00% | Add +2358.7% | 261,876 | $1.4M |
| HighVista Strategies LLC | 0.34% | New | 245,532 | $1.3M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 210,249 | $1.1M |
| Boothbay Fund Management, LLC | 0.03% | New | 205,024 | $1.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 191,724 | $1.0M |
| State of Wisconsin Investment Board | 0.00% | Add +347.9% | 185,423 | $996K |
| UBS Group AG | 0.00% | Reduce -15.3% | 167,856 | $901K |
| AQR Capital Management | 0.00% | Add +162.4% | 155,218 | $834K |
| Rafferty Asset Management, LLC | 0.00% | Add +113.8% | 151,743 | $815K |
| Alps Advisors Inc. | 0.00% | Add +75.9% | 146,040 | $784K |
| Wells Fargo & Company | 0.00% | Add +112.4% | 144,798 | $778K |
| ADAR1 Capital Management, LLC | 0.06% | Add +178.0% | 139,000 | $746K |
| Rhumbline Advisers | 0.00% | Reduce -3.4% | 134,605 | $723K |
| Gsa Capital Partners LLP | 0.06% | New | 133,810 | $719K |
| Squarepoint Ops LLC | 0.00% | Add +43.6% | 126,192 | $678K |
| Brevan Howard Capital Management LP | 0.01% | Add +158.4% | 118,528 | $636K |
| XTX Topco Ltd | 0.02% | Add +582.2% | 115,634 | $621K |
| Deutsche Bank AG | 0.00% | Add +14.1% | 109,273 | $587K |
| Creative Planning | 0.00% | Add +77.5% | 108,144 | $581K |
| SG Americas Securities, LLC | 0.00% | Reduce -28.6% | 106,533 | $572K |
| Citadel Advisors | 0.00% | Reduce -54.7% | 105,682 | $568K |
| NEOS Investment Management LLC | 0.00% | New | 101,676 | $546K |
| Tema ETFs LLC | 0.04% | New | 100,176 | $538K |
| CM Management, LLC | 0.45% | Reduce -33.3% | 100,000 | $537K |
| Alliancebernstein L.P. | 0.00% | Reduce -19.4% | 83,940 | $451K |
| SummitTX Capital, L.P. | 0.01% | New | 81,449 | $437K |
| Raymond James Financial Inc. | 0.00% | New | 80,142 | $430K |
| Atom Investors LP | 0.03% | Reduce -27.6% | 77,281 | $415K |
| MetLife Investment Management, LLC | 0.00% | Add +26.8% | 73,985 | $397K |
| T. Rowe Price Associates Inc. | 0.00% | Add +24.6% | 70,488 | $379K |
| Jane Street Group, LLC | 0.00% | Add +121.2% | 70,063 | $376K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +39.6% | 69,576 | $374K |
| Franklin Resources Inc. | 0.00% | New | 66,607 | $358K |
| Invesco Ltd. | 0.00% | Add +5.3% | 63,901 | $343K |
| Persistent Asset Partners Ltd | 0.15% | New | 57,253 | $307K |
| Profund Advisors LLC | 0.01% | Add +247.6% | 57,246 | $307K |
| Graham Capital Management, L.P. | 0.01% | New | 53,427 | $287K |
| Virtus Investment Advisers, LLC | 0.08% | New | 51,556 | $277K |
| D. E. Shaw & Co. | 0.00% | New | 51,482 | $276K |
| Susquehanna International Group, LLP | 0.00% | Add +124.2% | 44,742 | $240K |
| LPL Financial LLC | 0.00% | Add +4.7% | 44,470 | $239K |
| Axq Capital, LP | 0.05% | New | 41,378 | $222K |
| American Century Companies Inc. | 0.00% | New | 40,412 | $217K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +21.6% | 40,325 | $217K |
| Intech Investment Management LLC | 0.00% | No change | 38,936 | $209K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +25.3% | 35,503 | $191K |
| SmartHarvest Portfolios, LLC | 0.06% | — | 34,715 | $186K |
| Simplicity Wealth,LLC | 0.01% | Reduce -8.6% | 33,869 | $182K |
| New York State Common Retirement Fund | 0.00% | No change | 30,407 | $163K |
| Caxton Corp. | 3.70% | Reduce -44.9% | 29,495 | $158K |
| Avanza Fonder AB | 0.00% | New | 27,347 | $147K |
| Walleye Trading LLC | 0.00% | No change | 25,000 | $134K |
| Caitong International Asset Management Co., Ltd | 0.03% | New | 24,579 | $132K |
| DV Trading LLC | 0.01% | — | 24,207 | $130K |
| Stifel Financial Corp. | 0.00% | New | 23,973 | $129K |
| ProShare Advisors LLC | 0.00% | Add +41.0% | 23,972 | $129K |
| Abel Hall, LLC | 0.03% | New | 22,882 | $123K |
| Independent Financial Group, LLC | 0.00% | New | 22,779 | $122K |
| Voya Investment Management LLC | 0.00% | Add +31.5% | 22,629 | $122K |
| Captrust Financial Advisors | 0.00% | Add +1.6% | 20,846 | $112K |
| Welch & Forbes LLC | 0.00% | Add +26.7% | 19,000 | $102K |
| Focus Partners Wealth | 0.00% | Add +17.6% | 18,595 | $100K |
| Independent Advisor Alliance | 0.00% | No change | 17,894 | $96K |
| Sig Brokerage, LP | 0.03% | Reduce -35.2% | 17,076 | $92K |
| Sequoia Financial Advisors, LLC | 0.00% | Add +0.9% | 15,894 | $85K |
| BNP Paribas Financial Markets | 0.00% | Reduce -19.9% | 15,645 | $84K |
| Two Sigma Advisers, LP | 0.00% | New | 15,200 | $82K |
| Canada Pension Plan Investment Board | 0.00% | New | 14,900 | $80K |
| M&T Bank Corp | 0.00% | New | 14,894 | $80K |
| Victory Capital Management Inc. | 0.00% | Add +13.1% | 14,311 | $77K |
| Rovin Capital /Ut/ | 0.02% | No change | 13,495 | $72K |
| EntryPoint Capital, LLC | 0.03% | New | 13,163 | $71K |
| Neuberger Berman Group LLC | 0.00% | New | 12,807 | $69K |
| Legal & General Group Plc | 0.00% | Add +32.3% | 12,753 | $68K |
| North Star Investment Management Corp. | 0.00% | No change | 12,500 | $67K |
| Quadrature Capital Ltd | 0.00% | Reduce -74.1% | 12,293 | $66K |
| Strategic Wealth Partners, Ltd. | 0.00% | No change | 12,100 | $65K |
| Russell Investments Group, Ltd. | 0.00% | Add +48.5% | 11,558 | $62K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +40.9% | 10,621 | $57K |
| Stonebrook Private Inc. | 0.01% | No change | 10,230 | $55K |
| Xponance LLC | 0.00% | New | 10,201 | $55K |
| Cygnus Capital Advisors, LLC | 0.04% | — | 10,000 | $54K |
| Prelude Capital Management, LLC | 0.00% | New | 10,000 | $54K |
| Simplex Trading, LLC | 0.00% | Add +117.7% | 8,912 | $48K |
| California State Teachers Retirement System | 0.00% | Add +8.9% | 8,056 | $43K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 6,000 | $32K |
| MCF Advisors LLC | 0.00% | No change | 5,540 | $30K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 5,248 | $28K |
| Group One Trading LLC | 0.00% | New | 5,244 | $28K |
| Acadian Asset Management LLC | 0.00% | New | 4,867 | $26K |
| Fortitude Family Office, LLC | 0.01% | Reduce -7.8% | 4,591 | $25K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -29.8% | 4,370 | $23K |
| Amalgamated Bank | 0.00% | Add +33.6% | 4,111 | $22K |
| Royal Bank of Canada | 0.00% | Reduce -99.8% | 3,821 | $21K |
| Sterling Capital Management LLC | 0.00% | Add +14.8% | 3,827 | $21K |
| VSM Wealth Advisory, LLC | 0.00% | New | 3,000 | $16K |
| Cwm, LLC | 0.00% | Add +61.8% | 3,059 | $16K |
| Rockefeller Capital Management L.P. | 0.00% | New | 2,042 | $11K |
| Cape Investment Advisory, Inc. | 0.00% | Add +52.0% | 2,002 | $11K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -71.9% | 1,698 | $9K |
| Optiver Holding B.V. | 0.00% | Reduce -33.3% | 1,096 | $6K |
| Farther Finance Advisors, LLC | 0.00% | Add +75.3% | 680 | $4K |
| Bessemer Group Inc. | 0.00% | No change | 526 | $3K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 500 | $3K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -92.9% | 413 | $2K |
| Quadrant Capital Group LLC | 0.00% | No change | 405 | $2K |
| National Bank of Canada | 0.00% | New | 242 | $1K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -28.2% | 237 | $1K |
| Marshall & Sterling Wealth Advisors Inc. | 0.00% | No change | 200 | $1K |
| Rothschild Investment LLC | 0.00% | Add +36.7% | 164 | $881 |
| Smartleaf Asset Management LLC | 0.00% | New | 69 | $371 |
| Osaic Holdings, Inc. | 0.00% | New | 57 | $306 |
| CIBC Private Wealth Group LLC | 0.00% | New | 38 | $204 |
| GAMMA Investing LLC | 0.00% | New | 29 | $156 |
| SJS Investment Consulting Inc. | 0.00% | New | 27 | $145 |
| MAI Capital Management | 0.00% | New | 24 | $129 |
| Allworth Financial LP | 0.00% | Add +400.0% | 20 | $108 |
| Arax Advisory Partners | 0.00% | Reduce -92.0% | 18 | $97 |
| Essential Partners LLC | 0.00% | Reduce -52.6% | 9 | $48 |
| Sunbelt Securities, Inc. | 0.00% | No change | 8 | $43 |
| IFP Advisors, Inc | 0.00% | No change | 6 | $32 |
| Hughes Financial Services, LLC | 0.00% | New | 1 | $5 |
"% of holder's portfolio" is CMPX's weight in each manager's 13F, not the share of Compass Therapeutics Inc. the manager owns.